Lycoramin (BioDeep_00000396793)

 

Secondary id: BioDeep_00000009190

PANOMIX_OTCML-2023


代谢物信息卡片


6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,7,8,9,10,11,12-octahydro-3-methoxy-11-methyl-, (4aS,6S,8aR)-

化学式: C17H23NO3 (289.1677848)
中文名称: 二氢加兰他敏, 谷氨酰胺
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 31.25%

分子结构信息

SMILES: C1N(CC[C@]23c4c1ccc(c4O[C@H]2C[C@H](CC3)O)OC)C
InChI: InChI=1S/C17H23NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-4,12,14,19H,5-10H2,1-2H3/t12-,14-,17-/m0/s1

描述信息

Lycoramine is a benzazepine.
Lycoramine is a natural product found in Lycoris sanguinea, Hymenocallis rotata, and other organisms with data available.
Lycoramine, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor[1][2].
Lycoramine, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor[1][2].

同义名列表

21 个代谢物同义名

6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,7,8,9,10,11,12-octahydro-3-methoxy-11-methyl-, (4aS,6S,8aR)-; 6H-BENZOFURO(3A,3,2-EF)(2)BENZAZEPIN-6-OL, 4A,5,7,8,9,10,11,12-OCTAHYDRO-3-METHOXY-11-METHYL-, (4AS,6S,8AR)-; (4AS,6S,8AR)-3-METHOXY-11-METHYL-5,6,7,8,9,10,11,12-OCTAHYDRO-4AH-(1)BENZOFURO(3A,3,2-EF)(2)BENZAZEPIN-6-OL; (4aS,6S,8aR)-3-methoxy-11-methyl-4a,5,7,8,9,10,11,12-octahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-ol; (1R,12S,14S)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0?,??.0?,??]heptadeca-6(17),7,9-trien-14-ol; (1R,12S,14S)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9-trien-14-ol; GALANTAMINE HYDROBROMIDE IMPURITY C [EP IMPURITY]; GALANTHAMINE, 1,2-DIHYDRO-; 1,2-Dihydrogalanthamine; GALANTHAMINE, DIHYDRO-; Lycoramine free base; Dihydrogalanthamine; Dihydro Galantamine; (+-)-lycoramine; LYCORAMINE [MI]; UNII-TAG8LU84K2; (-)-lycoramine; TAG8LU84K2; Lycoramine; Lycoramin; AC1L9F2N



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Eman Shawky, Samah M El Sohafy, Jean Paulo de Andrade, Warley de Souza Borges. Profiling of acetylcholinesterase inhibitory alkaloids from some Crinum, Habranthus and Zephyranthes species by GC-MS combined with multivariate analyses and in silico studies. Natural product research. 2021 Mar; 35(5):807-814. doi: 10.1080/14786419.2019.1598989. [PMID: 30990078]
  • Guanqun Zhan, Junfei Zhou, Rong Liu, Tingting Liu, Guoli Guo, Jianping Wang, Ming Xiang, Yongbo Xue, Zengwei Luo, Yonghui Zhang, Guangmin Yao. Galanthamine, Plicamine, and Secoplicamine Alkaloids from Zephyranthes candida and Their Anti-acetylcholinesterase and Anti-inflammatory Activities. Journal of natural products. 2016 Apr; 79(4):760-6. doi: 10.1021/acs.jnatprod.5b00681. [PMID: 26913788]
  • Yuqiong Zhang, Yong Li, Jianhui Zhou, Na Chen, Meifang Wang, Zhaorong Dong, Cuiyun Gao, Yanlong Zhong. [Effect of precursor on growth and accumulation of alkaloids of Lycoris radiata suspension cells]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 2014 Feb; 30(2):247-54. doi: ". [PMID: 24945053]
  • Deepali Katoch, Shiv Kumar, Neeraj Kumar, Bikram Singh. Simultaneous quantification of Amaryllidaceae alkaloids from Zephyranthes grandiflora by UPLC-DAD/ESI-MS/MS. Journal of pharmaceutical and biomedical analysis. 2012 Dec; 71(?):187-92. doi: 10.1016/j.jpba.2012.08.001. [PMID: 22939505]
  • Hong-Mei Mu, Ren Wang, Xiao-Dan Li, Yu-Mei Jiang, Feng Peng, Bing Xia. Alkaloid accumulation in different parts and ages of Lycoris chinensis. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2010 Jul; 65(7-8):458-62. doi: 10.1515/znc-2010-7-807. [PMID: 20737914]