8FEU38L6GD (BioDeep_00000396791)

 

Secondary id: BioDeep_00000007868, BioDeep_00000393889

PANOMIX_OTCML-2023


代谢物信息卡片


1,3,5-Trihydroxy-8-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-9H-xanthen-9-one

化学式: C19H18O11 (422.0849078)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=C2C(=C1O)OC3=CC(=CC(=C3C2=O)O)O)OC4C(C(C(C(O4)CO)O)O)O
InChI: InChI=1S/C19H18O11/c20-5-11-14(24)16(26)17(27)19(30-11)29-9-2-1-7(22)18-13(9)15(25)12-8(23)3-6(21)4-10(12)28-18/h1-4,11,14,16-17,19-24,26-27H,5H2/t11-,14-,16+,17-,19-/m1/s1

描述信息

Norswertianolin is a beta-D-glucoside that is bellidin in which a beta-D-glucopyranosyl residue is attached at position O-8. A natural product found particularly in Gentiana campestris and Gentiana germanica. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor and a metabolite. It is a member of xanthones and a beta-D-glucoside. It is functionally related to a bellidin.
Norswertianolin is a natural product found in Gentianella amarella, Swertia macrosperma, and other organisms with data available.
A beta-D-glucoside that is bellidin in which a beta-D-glucopyranosyl residue is attached at position O-8. A natural product found particularly in Gentiana campestris and Gentiana germanica.
Norswertianolin acts as a CSE activator and is isolated from G. acuta. Norswertianolin may be a potential agent for cardiovascular diseases[1][2].

同义名列表

15 个代谢物同义名

1,3,5-Trihydroxy-8-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-9H-xanthen-9-one; 1,3,5-trihydroxy-8-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-9H-xanthen-9-one; 1,3,5-trihydroxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyxanthen-9-one; 9H-Xanthen-9-one, 8-(beta-D-glucopyranosyloxy)-1,3,5-trihydroxy-; 8-(beta-D-Glucopyranosyloxy)-1,3,5-trihydroxy-9H-xanthen-9-one; 4,6,8-trihydroxy-9-oxo-9H-xanthen-1-yl beta-D-glucopyranoside; 1,3,5-Trihydroxyxanthone 8-O-beta-D-glucopyranoside; 3-O-Demethylbellidifolin 8-O-beta-D-glucopyranoside; 1,3,5,8-Tetrahydroxyxanthen-9-one 8-glucoside; 3,5,8-Trihydroxyxanthone-1-O-glucoside; bellidin-8-O-beta-D-glucopyranoside; Demethylbellidifolin-8-O-glucoside; 8-O-Glucosyldesmethylbellidifolin; Norswertianolin; 8FEU38L6GD



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Kai Ren, He Su, Li-Juan Lv, Le-Tai Yi, Xue Gong, Lian-Sheng Dang, Rui-Fen Zhang, Min-Hui Li. Effects of Four Compounds from Gentianella acuta (Michx.) Hulten on Hydrogen Peroxide-Induced Injury in H9c2 Cells. BioMed research international. 2019; 2019(?):2692970. doi: 10.1155/2019/2692970. [PMID: 30800665]
  • Gordana Tovilovic-Kovacevic, Dijana Krstic-Milosevic, Branka Vinterhalter, Mina Toljic, Vladimir Perovic, Vladimir Trajkovic, Ljubica Harhaji-Trajkovic, Nevena Zogovic. Xanthone-rich extract from Gentiana dinarica transformed roots and its active component norswertianin induce autophagy and ROS-dependent differentiation of human glioblastoma cell line. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2018 Aug; 47(?):151-160. doi: 10.1016/j.phymed.2018.03.052. [PMID: 30166100]
  • Yun Chen, Guo-Kai Wang, Can Wu, Min-Jian Qin. [Chemical constituents of Gentiana rhodantha]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2013 Feb; 38(3):362-5. doi: ". [PMID: 23668010]
  • Shi-Sheng Wang, Xiu-Wen Han, Qing Xu, Hong-Bin Xiao, Xiu-Mei Liu, Yu-Guang Du, Xin-Miao Liang. Xanthone glycosides from Swertia franchetiana. Journal of Asian natural products research. 2005 Apr; 7(2):175-9. doi: 10.1080/10286020310001625111. [PMID: 15621623]
  • Guang-yao Zeng, Gui-shan Tan, Kang-ping Xu, Xiao-ping Xu, Fu-shuang Li, Jian-bing Tan, Gao-yun Hu. [Water-soluble chemical constituents of Swertia davidi Franch]. Yao xue xue bao = Acta pharmaceutica Sinica. 2004 May; 39(5):351-3. doi: . [PMID: 15338877]