Solanine (BioDeep_00000396787)

   

PANOMIX_OTCML-2023 Toxin natural product


代谢物信息卡片


(2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-2-[[(1S,2S,7S,10R,11S,14S,15R,16S,17R,20S,23S)-10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracos-4-en-7-yl]oxy]-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol

化学式: C45H73NO15 (867.498)
中文名称: α-茄碱, A-茄碱
谱图信息: 最多检出来源 Viridiplantae(plant) 97.66%

分子结构信息

SMILES: CC1CCC2C(C3C(N2C1)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)O)OC8C(C(C(C(O8)CO)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C
InChI: InChI=1S/C45H73NO15/c1-19-6-9-27-20(2)31-28(46(27)16-19)15-26-24-8-7-22-14-23(10-12-44(22,4)25(24)11-13-45(26,31)5)57-43-40(61-41-37(54)35(52)32(49)21(3)56-41)39(34(51)30(18-48)59-43)60-42-38(55)36(53)33(50)29(17-47)58-42/h7,19-21,23-43,47-55H,6,8-18H2,1-5H3/t19-,20+,21-,23-,24+,25-,26-,27+,28-,29+,30+,31-,32-,33+,34-,35+,36-,37+,38+,39-,40+,41-,42-,43+,44-,45-/m0/s1

描述信息

A glycoalkaloid poison found in species of the nightshade family (Solanaceae), such as the potato (Solanum tuberosum). It is a trisccharide derivative of solanidine [(22beta)-solanid-5-en-3beta-ol].
Solanine is a glycoalkaloid poison found in species of the nightshade family (Solanaceae), such as the potato (Solanum tuberosum). It is a trisccharide derivative of solanidine [(22beta)-solanid-5-en-3beta-ol]. It has a role as a phytotoxin, an antineoplastic agent, an apoptosis inducer and a plant metabolite. It is a steroid saponin, a trisaccharide derivative, an organic heterohexacyclic compound and a glycoalkaloid. It is functionally related to a solanidine.
(2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-2-[[(1S,2S,7S,10R,11S,14S,15R,16S,17R,20S,23S)-10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracos-4-en-7-yl]oxy]-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol is a natural product found in Capsicum annuum, Solanum tuberosum, and Bos taurus with data available.
A mixture of alpha-chaconine and alpha-solanine, found in SOLANACEAE plants.
α-solanine, a bioactive component and one of the major steroidal glycoalkaloids in Solanum nigrum, has been observed to inhibit growth and induce apoptosis in cancer cells[1].
α-solanine, a bioactive component and one of the major steroidal glycoalkaloids in Solanum nigrum, has been observed to inhibit growth and induce apoptosis in cancer cells[1].

同义名列表

17 个代谢物同义名

Solanine; (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-2-[[(1S,2S,7S,10R,11S,14S,15R,16S,17R,20S,23S)-10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracos-4-en-7-yl]oxy]-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol; beta-D-Galactopyranoside, (3beta)-solanid-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->3)]-; solanid-5-en-3beta-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)]-beta-D-galactopyranoside; alpha-Solanine, from potato sprouts, >=95\\%; alpha-Solanine with HPLC; Prestwick3_000640; alpha -Solanine; UNII-3FYV8328OK; alpha-Solanine; BPBio1_000704; alpha-Solanin; 3FYV8328OK; α-Solanine; -Solanine; Solanin; Solanine



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(2)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Jinyi Zhou, Jinting Wu, Fangda Fu, Sai Yao, Wenbiao Zheng, Weibin Du, Huan Luo, Hongting Jin, Peijian Tong, Chengliang Wu, Hongfeng Ruan. α-Solanine attenuates chondrocyte pyroptosis to improve osteoarthritis via suppressing NF-κB pathway. Journal of cellular and molecular medicine. 2024 Feb; 28(4):e18132. doi: 10.1111/jcmm.18132. [PMID: 38345195]
  • Xudong Ma, Yijun Li, Daoming Liang, Fan Jiang, Lu Zhang, Wanhong Song, Baosheng Wan, Chuqi Xia, Qiyu Lu. Solanine induces ferroptosis in colorectal cancer cells through ALOX12B/ADCY4 molecular axis. The Journal of pharmacy and pharmacology. 2024 Jan; ?(?):. doi: 10.1093/jpp/rgad122. [PMID: 38244223]
  • Xiaolong Tang, YingYing Guo, Sijia Zhang, Xin Wang, Yuhao Teng, Qingjiang Jin, Qinglei Jin, Wei Shen, Ruiping Wang. Solanine Represses Gastric Cancer Growth by Mediating Autophagy Through AAMDC/MYC/ATF4/Sesn2 Signaling Pathway. Drug design, development and therapy. 2023; 17(?):389-402. doi: 10.2147/dddt.s389764. [PMID: 36789094]
  • Przemysław Łukasz Kowalczewski, Anna Olejnik, Martyna Natalia Wieczorek, Joanna Zembrzuska, Katarzyna Kowalska, Jacek Lewandowicz, Grażyna Lewandowicz. Bioactive Substances of Potato Juice Reveal Synergy in Cytotoxic Activity against Cancer Cells of Digestive System Studied In Vitro. Nutrients. 2022 Dec; 15(1):. doi: 10.3390/nu15010114. [PMID: 36615771]
  • Sebastian Baur, Nicole Bellé, Hans Hausladen, Sebastian Wurzer, Laura Brehm, Timo D Stark, Ralph Hücklhoven, Thomas Hofmann, Corinna Dawid. Quantitation of Toxic Steroidal Glycoalkaloids and Newly Identified Saponins in Post-Harvest Light-Stressed Potato (Solanum tuberosum L.) Varieties. Journal of agricultural and food chemistry. 2022 Jul; 70(27):8300-8308. doi: 10.1021/acs.jafc.2c02578. [PMID: 35775364]
  • Shaimaa A Gouhar, Mahmoud T Abo-Elfadl, Amira M Gamal-Eldeen, Sherien M El-Daly. Involvement of miRNAs in response to oxidative stress induced by the steroidal glycoalkaloid α-solanine in hepatocellular carcinoma cells. Environmental toxicology. 2022 Feb; 37(2):212-223. doi: 10.1002/tox.23390. [PMID: 34655286]
  • Libin Wan, Haidong Gao, Huoliang Gao, Rui Du, Fayun Wang, Yong Wang, Mantang Chen. Selective extraction and determination of steroidal glycoalkaloids in potato tissues by electromembrane extraction combined with LC-MS/MS. Food chemistry. 2022 Jan; 367(?):130724. doi: 10.1016/j.foodchem.2021.130724. [PMID: 34352691]
  • Sebastian Baur, Oliver Frank, Hans Hausladen, Ralph Hückelhoven, Thomas Hofmann, Wolfgang Eisenreich, Corinna Dawid. Biosynthesis of α-solanine and α-chaconine in potato leaves (Solanum tuberosum L.) - A 13CO2 study. Food chemistry. 2021 Dec; 365(?):130461. doi: 10.1016/j.foodchem.2021.130461. [PMID: 34229992]
  • Ekta Bhattacharya, Suparna Mandal Biswas, Panchanan Pramanik. Maleic and L-tartaric acids as new anti-sprouting agents for potatoes during storage in comparison to other efficient sprout suppressants. Scientific reports. 2021 10; 11(1):20029. doi: 10.1038/s41598-021-99187-y. [PMID: 34625595]
  • Masaru Nakayasu, Naoyuki Umemoto, Ryota Akiyama, Kiyoshi Ohyama, Hyoung J Lee, Haruka Miyachi, Bunta Watanabe, Toshiya Muranaka, Kazuki Saito, Yukihiro Sugimoto, Masaharu Mizutani. Characterization of C-26 aminotransferase, indispensable for steroidal glycoalkaloid biosynthesis. The Plant journal : for cell and molecular biology. 2021 10; 108(1):81-92. doi: 10.1111/tpj.15426. [PMID: 34273198]
  • Ryota Akiyama, Bunta Watanabe, Masaru Nakayasu, Hyoung Jae Lee, Junpei Kato, Naoyuki Umemoto, Toshiya Muranaka, Kazuki Saito, Yukihiro Sugimoto, Masaharu Mizutani. The biosynthetic pathway of potato solanidanes diverged from that of spirosolanes due to evolution of a dioxygenase. Nature communications. 2021 02; 12(1):1300. doi: 10.1038/s41467-021-21546-0. [PMID: 33637735]
  • Miia J Rainio, Aigi Margus, Valtteri Virtanen, Leena Lindström, Juha-Pekka Salminen, Kari Saikkonen, Marjo Helander. Glyphosate-based herbicide has soil-mediated effects on potato glycoalkaloids and oxidative status of a potato pest. Chemosphere. 2020 Nov; 258(?):127254. doi: 10.1016/j.chemosphere.2020.127254. [PMID: 32559492]
  • Xia Yan, Miao Li, Lei Chen, Xiao Peng, Zu-Jun Que, Hong-Mei An, Ke-Ping Shen, Bing Hu. α‑Solanine inhibits growth and metastatic potential of human colorectal cancer cells. Oncology reports. 2020 05; 43(5):1387-1396. doi: 10.3892/or.2020.7519. [PMID: 32323807]
  • Rosanna C Hennessy, Søren D Nielsen, Mathias Greve-Poulsen, Lotte Bach Larsen, Ole Bandsholm Sørensen, Peter Stougaard. Discovery of a Bacterial Gene Cluster for Deglycosylation of Toxic Potato Steroidal Glycoalkaloids α-Chaconine and α-Solanine. Journal of agricultural and food chemistry. 2020 Feb; 68(5):1390-1396. doi: 10.1021/acs.jafc.9b07632. [PMID: 31935098]
  • Liang-Tzung Lin, Chen-Yen Choong, Chen-Jei Tai. Solanine Attenuated Hepatocarcinoma Migration and Invasion Induced by Acetylcholine. Integrative cancer therapies. 2020 Jan; 19(?):1534735420909895. doi: 10.1177/1534735420909895. [PMID: 32975458]
  • Weina Zhang, Cunwu Zuo, Zhongjian Chen, Yichen Kang, Shuhao Qin. RNA Sequencing Reveals That Both Abiotic and Biotic Stress-Responsive Genes are Induced during Expression of Steroidal Glycoalkaloid in Potato Tuber Subjected to Light Exposure. Genes. 2019 11; 10(11):. doi: 10.3390/genes10110920. [PMID: 31718041]
  • Bin Jia, Lixing Xu, Wenqiang Guan, Qiong Lin, Charles Brennan, Ruixiang Yan, Hui Zhao. Effect of citronella essential oil fumigation on sprout suppression and quality of potato tubers during storage. Food chemistry. 2019 Jun; 284(?):254-258. doi: 10.1016/j.foodchem.2019.01.119. [PMID: 30744854]
  • Rémi Beaulieu, Eric Grand, Imane Stasik, Jacques Attoumbré, Quentin Chesnais, Virginie Gobert, Arnaud Ameline, Philippe Giordanengo, José Kovensky. Synthesis and insecticidal activities of novel solanidine derivatives. Pest management science. 2019 Mar; 75(3):793-800. doi: 10.1002/ps.5180. [PMID: 30136365]
  • Masaru Nakayasu, Ryota Akiyama, Hyoung Jae Lee, Keishi Osakabe, Yuriko Osakabe, Bunta Watanabe, Yukihiro Sugimoto, Naoyuki Umemoto, Kazuki Saito, Toshiya Muranaka, Masaharu Mizutani. Generation of α-solanine-free hairy roots of potato by CRISPR/Cas9 mediated genome editing of the St16DOX gene. Plant physiology and biochemistry : PPB. 2018 Oct; 131(?):70-77. doi: 10.1016/j.plaphy.2018.04.026. [PMID: 29735370]
  • Xiaofen Ni, Jiajun Chen, Fengying Lu, Zhengzhong Yuan, Xiaofeng Xu, Zhen Hu, Lei Jiang. Anti-Cancer Effect of α-Solanine by Down-Regulating S100P Expression in Colorectal Cancer Cells. Recent patents on anti-cancer drug discovery. 2018; 13(2):240-247. doi: 10.2174/1574892813666180329163945. [PMID: 29600769]
  • Akhilesh Kumar, Edna Fogelman, Mira Weissberg, Zachariah Tanami, Richard E Veilleux, Idit Ginzberg. Lanosterol synthase-like is involved with differential accumulation of steroidal glycoalkaloids in potato. Planta. 2017 Dec; 246(6):1189-1202. doi: 10.1007/s00425-017-2763-z. [PMID: 28828630]
  • Anders Glynn, Annachiara Malin Igra, Salomon Sand, Nils Gunnar Ilbäck, Karl Erik Hellenäs, Johan Rosén, Bitte Aspenström-Fagerlund. Are additive effects of dietary surfactants on intestinal tight junction integrity an overlooked human health risk? - A mixture study on Caco-2 monolayers. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2017 Aug; 106(Pt A):314-323. doi: 10.1016/j.fct.2017.05.068. [PMID: 28576466]
  • Paul Dahlin, Marion C Müller, Sophia Ekengren, Lauren S McKee, Vincent Bulone. The Impact of Steroidal Glycoalkaloids on the Physiology of Phytophthora infestans, the Causative Agent of Potato Late Blight. Molecular plant-microbe interactions : MPMI. 2017 07; 30(7):531-542. doi: 10.1094/mpmi-09-16-0186-r. [PMID: 28510502]
  • Naoyuki Umemoto, Masaru Nakayasu, Kiyoshi Ohyama, Mari Yotsu-Yamashita, Masaharu Mizutani, Hikaru Seki, Kazuki Saito, Toshiya Muranaka. Two Cytochrome P450 Monooxygenases Catalyze Early Hydroxylation Steps in the Potato Steroid Glycoalkaloid Biosynthetic Pathway. Plant physiology. 2016 08; 171(4):2458-67. doi: 10.1104/pp.16.00137. [PMID: 27307258]
  • Louise Vida Traill Shepherd, Christine Anne Hackett, Colin James Alexander, James William McNicol, Julia Anne Sungurtas, Diane McRae, Kent Frank McCue, William Richardson Belknap, Howard Vivian Davies. Impact of light-exposure on the metabolite balance of transgenic potato tubers with modified glycoalkaloid biosynthesis. Food chemistry. 2016 Jun; 200(?):263-73. doi: 10.1016/j.foodchem.2015.12.095. [PMID: 26830588]
  • A F Sánchez-Maldonado, A Schieber, M G Gänzle. Antifungal activity of secondary plant metabolites from potatoes (Solanum tuberosum L.): Glycoalkaloids and phenolic acids show synergistic effects. Journal of applied microbiology. 2016 Apr; 120(4):955-65. doi: 10.1111/jam.13056. [PMID: 26786886]
  • Mohammad B Hossain, Nigel P Brunton, Dilip K Rai. Effect of Drying Methods on the Steroidal Alkaloid Content of Potato Peels, Shoots and Berries. Molecules (Basel, Switzerland). 2016 Mar; 21(4):403. doi: 10.3390/molecules21040403. [PMID: 27023503]
  • Roberta Fogliatto Mariot, Luisa Abruzzi de Oliveira, Marleen M Voorhuijzen, Martijn Staats, Ronald C B Hutten, Jeroen P van Dijk, Esther J Kok, Jeverson Frazzon. Characterization and Transcriptional Profile of Genes Involved in Glycoalkaloid Biosynthesis in New Varieties of Solanum tuberosum L. Journal of agricultural and food chemistry. 2016 Feb; 64(4):988-96. doi: 10.1021/acs.jafc.5b05519. [PMID: 26768994]
  • Emanuela Ventrella, Zbigniew Adamski, Ewa Chudzińska, Mariola Miądowicz-Kobielska, Paweł Marciniak, Ender Büyükgüzel, Kemal Büyükgüzel, Meltem Erdem, Patrizia Falabella, Laura Scrano, Sabino Aurelio Bufo. Solanum tuberosum and Lycopersicon esculentum Leaf Extracts and Single Metabolites Affect Development and Reproduction of Drosophila melanogaster. PloS one. 2016; 11(5):e0155958. doi: 10.1371/journal.pone.0155958. [PMID: 27213896]
  • Mendel Friedman. Chemistry and anticarcinogenic mechanisms of glycoalkaloids produced by eggplants, potatoes, and tomatoes. Journal of agricultural and food chemistry. 2015 Apr; 63(13):3323-37. doi: 10.1021/acs.jafc.5b00818. [PMID: 25821990]
  • Alessandra Tata, Consuelo J Perez, Tanam S Hamid, Mark A Bayfield, Demian R Ifa. Analysis of metabolic changes in plant pathosystems by imprint imaging DESI-MS. Journal of the American Society for Mass Spectrometry. 2015 Apr; 26(4):641-8. doi: 10.1007/s13361-014-1039-0. [PMID: 25510927]
  • R Xu, F Ali-Rachedi, N M Xavier, S Chambert, F Ferkous, Y Queneau, S J Cowling, E J Davis, J W Goodby. Self-organizing behaviour of glycosteroidal bolaphiles: insights into lipidic microsegregation. Organic & biomolecular chemistry. 2015 Jan; 13(3):783-92. doi: 10.1039/c4ob02191f. [PMID: 25388281]
  • Helen H Tai, Kraig Worrall, Yvan Pelletier, David De Koeyer, Larry A Calhoun. Comparative metabolite profiling of Solanum tuberosum against six wild Solanum species with Colorado potato beetle resistance. Journal of agricultural and food chemistry. 2014 Sep; 62(36):9043-55. doi: 10.1021/jf502508y. [PMID: 25144460]
  • Zbigniew Adamski, Zbigniew Adamski, Pawel Marciniak, Kazimierz Ziemnicki, Ender Büyükgüzel, Meltem Erdem, Kemal Büyükgüzel, Emanuela Ventrella, Patrizia Falabella, Massimo Cristallo, Rosanna Salvia, Sabino Aurelio Bufo, Laura Scrano. Potato leaf extract and its component, α-solanine, exert similar impacts on development and oxidative stress in Galleria mellonella L. Archives of insect biochemistry and physiology. 2014 Sep; 87(1):26-39. doi: 10.1002/arch.21177. [PMID: 25041927]
  • Xiuyao Zhang, Xinxin Cai, Xiaoyi Zhang. [Determination of alpha-solanine, alpha-chaconine and solanidine in plasma and urine by ultra-performance liquid chromatography-triple quadrupole mass spectrometry]. Se pu = Chinese journal of chromatography. 2014 Jun; 32(6):586-90. doi: 10.3724/sp.j.1123.2014.03001. [PMID: 25269255]
  • Jesus Valcarcel, Kim Reilly, Michael Gaffney, Nora O'Brien. Effect of genotype and environment on the glycoalkaloid content of rare, heritage, and commercial potato varieties. Journal of food science. 2014 May; 79(5):T1039-48. doi: 10.1111/1750-3841.12443. [PMID: 24697731]
  • Marcela Manrique-Moreno, Julián Londoño-Londoño, Małgorzata Jemioła-Rzemińska, Kazimierz Strzałka, Fernando Villena, Marcia Avello, Mario Suwalsky. Structural effects of the Solanum steroids solasodine, diosgenin and solanine on human erythrocytes and molecular models of eukaryotic membranes. Biochimica et biophysica acta. 2014 Jan; 1838(1 Pt B):266-77. doi: 10.1016/j.bbamem.2013.08.003. [PMID: 23954587]
  • Shiro Yamashoji, Takako Matsuda. Synergistic cytotoxicity induced by α-solanine and α-chaconine. Food chemistry. 2013 Nov; 141(2):669-74. doi: 10.1016/j.foodchem.2013.03.104. [PMID: 23790833]
  • Jacques Attoumbré, Philippe Giordanengo, Sylvie Baltora-Rosset. Solanidine isolation from Solanum tuberosum by centrifugal partition chromatography. Journal of separation science. 2013 Jul; 36(14):2379-85. doi: 10.1002/jssc.201300188. [PMID: 23640901]
  • Erik V Petersson, Usman Arif, Vera Schulzova, Veronika Krtková, Jana Hajšlová, Johan Meijer, Hans Christer Andersson, Lisbeth Jonsson, Folke Sitbon. Glycoalkaloid and calystegine levels in table potato cultivars subjected to wounding, light, and heat treatments. Journal of agricultural and food chemistry. 2013 Jun; 61(24):5893-902. doi: 10.1021/jf400318p. [PMID: 23692427]
  • Ender Büyükgüzel, Kemal Büyükgüzel, Meltem Erdem, Zbigniew Adamski, Zbigniew Adamski, Pawel Marciniak, Kazimierz Ziemnicki, Emanuela Ventrella, Laura Scrano, Sabino Aurelio Bufo. The influence of dietary α-solanine on the waxmoth Galleria mellonella L. Archives of insect biochemistry and physiology. 2013 May; 83(1):15-24. doi: 10.1002/arch.21089. [PMID: 23494897]
  • Mendel Friedman, Reuven Rasooly. Review of the inhibition of biological activities of food-related selected toxins by natural compounds. Toxins. 2013 Apr; 5(4):743-75. doi: 10.3390/toxins5040743. [PMID: 23612750]
  • Olivia M Kenny, Catherine M McCarthy, Nigel P Brunton, Mohammad B Hossain, Dilip K Rai, Stuart G Collins, Peter W Jones, Anita R Maguire, Nora M O'Brien. Anti-inflammatory properties of potato glycoalkaloids in stimulated Jurkat and Raw 264.7 mouse macrophages. Life sciences. 2013 Apr; 92(13):775-82. doi: 10.1016/j.lfs.2013.02.006. [PMID: 23454444]
  • Anupam Maurya, N Manika, Ram Kishore Verma, Subhash C Singh, Santosh Kumar Srivastava. Simple and reliable methods for the determination of three steroidal glycosides in the eight species of Solanum by reversed-phase HPLC coupled with diode array detection. Phytochemical analysis : PCA. 2013 Jan; 24(1):87-92. doi: 10.1002/pca.2387. [PMID: 22786841]
  • Miriam Frida Karlsson, Göran Birgersson, Peter Witzgall, Jonas Duus Stevens Lekfeldt, P A Nimal Punyasiri, Marie Bengtsson. Guatemalan potato moth Tecia solanivora distinguish odour profiles from qualitatively different potatoes Solanum tuberosum L. Phytochemistry. 2013 Jan; 85(?):72-81. doi: 10.1016/j.phytochem.2012.09.015. [PMID: 23122773]
  • Hannah Deusser, Cédric Guignard, Lucien Hoffmann, Danièle Evers. Polyphenol and glycoalkaloid contents in potato cultivars grown in Luxembourg. Food chemistry. 2012 Dec; 135(4):2814-24. doi: 10.1016/j.foodchem.2012.07.028. [PMID: 22980877]
  • Jacques Attoumbré, David Lesur, Philippe Giordanengo, Sylvie Baltora-Rosset. Preparative separation of glycoalkaloids α-solanine and α-chaconine by centrifugal partition chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Nov; 908(?):150-4. doi: 10.1016/j.jchromb.2012.09.025. [PMID: 23040988]
  • Søren Langkilde, Malene Schrøder, Thomas Frank, Louise V T Shepherd, Sean Conner, Howard V Davies, Otto Meyer, Jürgen Danier, Michael Rychlik, William R Belknap, Kent F McCue, Karl-Heinz Engel, Derek Stewart, Ib Knudsen, Morten Poulsen. Compositional and toxicological analysis of a GM potato line with reduced α-solanine content--a 90-day feeding study in the Syrian Golden hamster. Regulatory toxicology and pharmacology : RTP. 2012 Oct; 64(1):177-85. doi: 10.1016/j.yrtph.2012.06.018. [PMID: 22796474]
  • Chung-Io Kuo, Chi-Hsein Chao, Mei-Kuang Lu. Effects of auxins on the production of steroidal alkaloids in rapidly proliferating tissue and cell cultures of Solanum lyratum. Phytochemical analysis : PCA. 2012 Jul; 23(4):400-4. doi: 10.1002/pca.1371. [PMID: 22009634]
  • Idit Ginzberg, Muddarangappa Thippeswamy, Edna Fogelman, Ufuk Demirel, Alice M Mweetwa, James Tokuhisa, Richard E Veilleux. Induction of potato steroidal glycoalkaloid biosynthetic pathway by overexpression of cDNA encoding primary metabolism HMG-CoA reductase and squalene synthase. Planta. 2012 Jun; 235(6):1341-53. doi: 10.1007/s00425-011-1578-6. [PMID: 22205426]
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