CLQ52DLW7V (BioDeep_00000396769)

Main id: BioDeep_00000018778

 

PANOMIX_OTCML-2023


代谢物信息卡片


(6R)-6-[(5R,10S,12S,13R,14R,17R)-12-acetyloxy-4,4,10,13,14-pentamethyl-3,7,11,15-tetraoxo-2,5,6,12,16,17-hexahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid

化学式: C32H42O9 (570.2828682)
中文名称: 灵芝酸F
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)([C@](C1)2[H])C(CC[C@]2(C)C3=C([C@@]4(C(C[C@@H]([C@]4([C@H](OC(C)=O)C3=O)C)[C@H](C)CC(CC(C)C(O)=O)=O)=O)C)C1=O)=O
InChI: InChI=1S/C32H42O9/c1-15(11-18(34)12-16(2)28(39)40)19-13-23(37)32(8)24-20(35)14-21-29(4,5)22(36)9-10-30(21,6)25(24)26(38)27(31(19,32)7)41-17(3)33/h15-16,19,21,27H,9-14H2,1-8H3,(H,39,40)/t15-,16?,19-,21+,27-,30+,31+,32+/m1/s1

描述信息

Ganoderic acid F is a triterpenoid.
ganoderic acid F is a natural product found in Ganoderma lucidum with data available.
Ganoderic acid F is a ganoderic acid. Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium signaling, and endoplasmic reticulum stress[1][2].
Ganoderic acid F is a ganoderic acid. Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium signaling, and endoplasmic reticulum stress[1][2].

同义名列表

9 个代谢物同义名

(6R)-6-[(5R,10S,12S,13R,14R,17R)-12-acetyloxy-4,4,10,13,14-pentamethyl-3,7,11,15-tetraoxo-2,5,6,12,16,17-hexahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid; (6R)-6-((5R,10S,12S,13R,14R,17R)-12-Acetoxy-4,4,10,13,14-pentamethyl-3,7,11,15-tetraoxo-2,5,6,12,16,17-hexahydro-1H-cyclopenta(a)phenanthren-17-yl)-2-methyl-4-oxo-heptanoic acid; LANOST-8-EN-26-OIC ACID, 12-(ACETYLOXY)-3,7,11,15,23-PENTAOXO-, (12.BETA.)-; Lanost-8-en-26-oic acid, 12-(acetyloxy)-3,7,11,15,23-pentaoxo-, (12beta)-; (12.BETA.)-12-(ACETYLOXY)-3,7,11,15,23-PENTAOXOLANOST-8-EN-26-OIC ACID; (12beta)-12-(acetyloxy)-3,7,11,15,23-pentaoxolanost-8-en-26-oic acid; Ganoderic acid F; UNII-CLQ52DLW7V; CLQ52DLW7V



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Feiya Sheng, Lele Zhang, Songsong Wang, Lele Yang, Peng Li. Deacetyl Ganoderic Acid F Inhibits LPS-Induced Neural Inflammation via NF-κB Pathway Both In Vitro and In Vivo. Nutrients. 2019 Dec; 12(1):. doi: 10.3390/nu12010085. [PMID: 31892211]
  • Liwu Chen, Jian Du, Qiwen Dai, Hongcheng Zhang, Wensheng Pang, Juan Hu. Prediction of anti-tumor chemical probes of a traditional Chinese medicine formula by HPLC fingerprinting combined with molecular docking. European journal of medicinal chemistry. 2014 Aug; 83(?):294-306. doi: 10.1016/j.ejmech.2014.06.037. [PMID: 24974349]
  • Jiri Adamec, Amber Jannasch, Shailesh Dudhgaonkar, Andrej Jedinak, Miroslav Sedlak, Daniel Sliva. Development of a new method for improved identification and relative quantification of unknown metabolites in complex samples: determination of a triterpenoid metabolic fingerprint for the in situ characterization of Ganoderma bioactive compounds. Journal of separation science. 2009 Dec; 32(23-24):4052-8. doi: 10.1002/jssc.200900496. [PMID: 19937965]
  • Anita Thyagarajan, Jiahua Jiang, Amber Hopf, Jiri Adamec, Daniel Sliva. Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion. International journal of molecular medicine. 2006 Oct; 18(4):657-64. doi: 10.3892/ijmm.18.4.657. [PMID: 16964420]
  • K Koyama, T Imaizumi, M Akiba, K Kinoshita, K Takahashi, A Suzuki, S Yano, S Horie, K Watanabe, Y Naoi. Antinociceptive components of Ganoderma lucidum. Planta medica. 1997 Jun; 63(3):224-7. doi: 10.1055/s-2006-957658. [PMID: 9225603]