1S862DJ73F (BioDeep_00000396727)

   

PANOMIX_OTCML-2023


代谢物信息卡片


(3.BETA.,16.BETA.,17.ALPHA.,23R)-20-HYDROXY-16,23:16,30-DIEPOXYDAMMAR-24-EN-3-YL .ALPHA.-L-ARABINOFURANOSYL-(1->2)-(.BETA.-D-GLUCOPYRANOSYL-(1->3))-.BETA.-D-GLUCOPYRANOSIDE

化学式: C47H76O18 (928.5031)
中文名称: 白花猪母菜甙 A3, 假马齿苋皂素A3, 苦艾素A3
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=CC1CC(C2C3CCC4C5(CCC(C(C5CCC4(C36CC2(O1)OC6)C)(C)C)OC7C(C(C(C(O7)CO)O)OC8C(C(C(C(O8)CO)O)O)O)OC9C(C(C(O9)CO)O)O)C)(C)O)C
InChI: InChI=1S/C47H76O18/c1-21(2)14-22-15-45(7,57)38-23-8-9-28-43(5)12-11-29(42(3,4)27(43)10-13-44(28,6)46(23)19-47(38,65-22)58-20-46)62-41-37(64-39-34(55)31(52)25(17-49)60-39)36(32(53)26(18-50)61-41)63-40-35(56)33(54)30(51)24(16-48)59-40/h14,22-41,48-57H,8-13,15-20H2,1-7H3/t22-,23+,24+,25-,26+,27-,28+,29-,30+,31-,32+,33-,34+,35+,36-,37+,38-,39-,40-,41-,43-,44+,45-,46-,47-/m0/s1

描述信息

Bacoside a3 is a triterpenoid.
Bacoside A3 is a natural product found in Bacopa monnieri with data available.
Bacoside A3, a triterpenoid saponin, is one of the major active constituents in Bacopa monnieri. Bacoside A3 has neuroprotective activity[1].

同义名列表

12 个代谢物同义名

(3.BETA.,16.BETA.,17.ALPHA.,23R)-20-HYDROXY-16,23:16,30-DIEPOXYDAMMAR-24-EN-3-YL .ALPHA.-L-ARABINOFURANOSYL-(1->2)-(.BETA.-D-GLUCOPYRANOSYL-(1->3))-.BETA.-D-GLUCOPYRANOSIDE; beta-D-Glucopyranoside, (3beta,16beta,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-yl O-alpha-L-arabinofuranosyl-(1-2)-O-(beta-D-glucopyranosyl-(1-3))-; (3beta,16beta,23R)-16,23:16,30-Diepoxy-20-hydroxydammar-24-en-3-yl O-alpha-L-arabinofuranosyl-(1-2)-O-(beta-D-glucopyranosyl-(1-3))-beta-D-Glucopyranoside; 3-beta-((O-beta-D-glucopyranosyl(1-3)-O-(alpha-L-arabinofuranosyl(1-2))-O-beta-D-glucopyranosyl)oxy)jujubogenin; Bacoside A3, United States Pharmacopeia (USP) Reference Standard; BACOSIDE A3 (CONSTITUENT OF BACOPA) [DSC]; Bacoside A3, analytical standard; BACOSIDE A3 [USP-RS]; UNII-1S862DJ73F; Bacoside a3(p); Bacoside A3; 1S862DJ73F



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Qing-Ke Bai, Zhen-Guo Zhao. Isolation and neuronal apoptosis inhibitory property of bacoside-A3 via downregulation of β-amyloid induced inflammatory response. Biotechnology and applied biochemistry. 2022 Apr; 69(2):726-734. doi: 10.1002/bab.2147. [PMID: 33687113]
  • Vini C Sekhar, Gayathri Viswanathan, Sabulal Baby. Insights Into the Molecular Aspects of Neuroprotective Bacoside A and Bacopaside I. Current neuropharmacology. 2019; 17(5):438-446. doi: 10.2174/1570159x16666180419123022. [PMID: 29676230]
  • Rajbir Singh, Ramakrishna Rachumallu, Manisha Bhateria, Jagadeesh Panduri, Rabi Sankar Bhatta. In vitro effects of standardized extract of Bacopa monniera and its five individual active constituents on human P-glycoprotein activity. Xenobiotica; the fate of foreign compounds in biological systems. 2015; 45(8):741-9. doi: 10.3109/00498254.2015.1017752. [PMID: 25869246]
  • Khalid Rauf, Fazal Subhan, Muzaffar Abbas, Syed Mobasher Ali, Gowhar Ali, Muhammad Ashfaq, Ghulam Abbas. Inhibitory effect of bacopasides on spontaneous morphine withdrawal induced depression in mice. Phytotherapy research : PTR. 2014 Jun; 28(6):937-9. doi: 10.1002/ptr.5081. [PMID: 24243728]
  • Mundkinajeddu Deepak, Agarwal Amit. 'Bacoside B'--the need remains for establishing identity. Fitoterapia. 2013 Jun; 87(?):7-10. doi: 10.1016/j.fitote.2013.03.011. [PMID: 23506783]
  • Sukanya Majumdar, Saraswati Garai, Sumita Jha. Use of the cryptogein gene to stimulate the accumulation of Bacopa saponins in transgenic Bacopa monnieri plants. Plant cell reports. 2012 Oct; 31(10):1899-909. doi: 10.1007/s00299-012-1303-3. [PMID: 22733208]
  • Khalid Rauf, Fazal Subhan, Robert D E Sewell. A Bacoside containing Bacopa monnieri extract reduces both morphine hyperactivity plus the elevated striatal dopamine and serotonin turnover. Phytotherapy research : PTR. 2012 May; 26(5):758-63. doi: 10.1002/ptr.3631. [PMID: 22105846]
  • Charinrat Tothiam, Watoo Phrompittayarat, Waraporn Putalun, Hiroyuki Tanaka, Seiichi Sakamoto, Ikhlas A Khan, Kornkanok Ingkaninan. An enzyme-linked immunosorbant assay using monoclonal antibody against bacoside A₃ for determination of jujubogenin glycosides in Bacopa monnieri (L.) Wettst. Phytochemical analysis : PCA. 2011 Sep; 22(5):385-91. doi: 10.1002/pca.1293. [PMID: 21413093]
  • Khalid Rauf, Fazal Subhan, Muzaffar Abbas, Amir Badshah, Ihsan Ullah, Sami Ullah. Effect of Bacopasides on acquisition and expression of morphine tolerance. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2011 Jul; 18(10):836-42. doi: 10.1016/j.phymed.2011.01.023. [PMID: 21377853]
  • K Sairam, C V Rao, M D Babu, R K Goel. Prophylactic and curative effects of Bacopa monniera in gastric ulcer models. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2001 Nov; 8(6):423-30. doi: 10.1078/s0944-7113(04)70060-4. [PMID: 11824516]
  • R Pawar, C Gopalakrishnan, K K Bhutani. Dammarane triterpene saponin from Bacopa monniera as the superoxide inhibitor in polymorphonuclear cells. Planta medica. 2001 Nov; 67(8):752-4. doi: 10.1055/s-2001-18351. [PMID: 11731921]