hamamelitanin (BioDeep_00000396661)

Main id: BioDeep_00000019932

 

PANOMIX_OTCML-2023


代谢物信息卡片


[(2S,3S,4S)-3,4,5-trihydroxy-4-[(3,4,5-trihydroxybenzoyl)oxymethyl]oxolan-2-yl]methyl 3,4,5-trihydroxybenzoate

化学式: C20H20O14 (484.085302)
中文名称: 金缕梅单宁, 金缕梅素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=C(C=C(C(=C1O)O)O)C(=O)OCC2C(C(C(O2)O)(COC(=O)C3=CC(=C(C(=C3)O)O)O)O)O
InChI: InChI=1S/C20H20O14/c21-9-1-7(2-10(22)14(9)25)17(28)32-5-13-16(27)20(31,19(30)34-13)6-33-18(29)8-3-11(23)15(26)12(24)4-8/h1-4,13,16,19,21-27,30-31H,5-6H2/t13-,16-,19?,20-/m0/s1

描述信息

Hamamelitannin is a gallate ester.
Hamamelofuranose 25-digallate is a natural product found in Hamamelis virginiana and Liquidambar formosana with data available.

同义名列表

9 个代谢物同义名

[(2S,3S,4S)-3,4,5-trihydroxy-4-[(3,4,5-trihydroxybenzoyl)oxymethyl]oxolan-2-yl]methyl 3,4,5-trihydroxybenzoate; ((2S,3S,4S)-3,4,5-trihydroxytetrahydrofuran-2,4-diyl)bis(methylene) bis(3,4,5-trihydroxybenzoate); 2,5-Digalloylhamamelofuranose; Hamamelofuranose2,5-digallate; Hamamelofuranose 25-digallate; 2,5-di-O-galloyl hamamelose; digalloylhamamelose; Hamamelitannin; hamamelitanin



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Praveen Kumar Issac, Ajay Guru, Sri Snehaa Chandrakumar, Christy Lite, N T Saraswathi, Mariadhas Valan Arasu, Naif Abdullah Al-Dhabi, Aziz Arshad, Jesu Arockiaraj. Molecular process of glucose uptake and glycogen storage due to hamamelitannin via insulin signalling cascade in glucose metabolism. Molecular biology reports. 2020 Sep; 47(9):6727-6740. doi: 10.1007/s11033-020-05728-5. [PMID: 32809102]
  • Susana Sánchez-Tena, María L Fernández-Cachón, Anna Carreras, M Luisa Mateos-Martín, Noelia Costoya, Mary P Moyer, María J Nuñez, Josep L Torres, Marta Cascante. Hamamelitannin from witch hazel (Hamamelis virginiana) displays specific cytotoxic activity against colon cancer cells. Journal of natural products. 2012 Jan; 75(1):26-33. doi: 10.1021/np200426k. [PMID: 22216935]
  • Huafu Wang, Gordon J Provan, Keith Helliwell. Determination of hamamelitannin, catechins and gallic acid in witch hazel bark, twig and leaf by HPLC. Journal of pharmaceutical and biomedical analysis. 2003 Nov; 33(4):539-44. doi: 10.1016/s0731-7085(03)00303-0. [PMID: 14623578]
  • Andreas Dauer, Andreas Hensel, Evelyne Lhoste, Siegfried Knasmüller, Volker Mersch-Sundermann. Genotoxic and antigenotoxic effects of catechin and tannins from the bark of Hamamelis virginiana L. in metabolically competent, human hepatoma cells (Hep G2) using single cell gel electrophoresis. Phytochemistry. 2003 May; 63(2):199-207. doi: 10.1016/s0031-9422(03)00104-3. [PMID: 12711142]
  • Hye Rhi Choi, Jae Sue Choi, Yong Nam Han, Song Ja Bae, Hae Young Chung. Peroxynitrite scavenging activity of herb extracts. Phytotherapy research : PTR. 2002 Jun; 16(4):364-7. doi: 10.1002/ptr.904. [PMID: 12112294]
  • Solomon Habtemariam. Hamamelitannin from Hamamelis virginiana inhibits the tumour necrosis factor-alpha (TNF)-induced endothelial cell death in vitro. Toxicon : official journal of the International Society on Toxinology. 2002 Jan; 40(1):83-8. doi: 10.1016/s0041-0101(01)00195-7. [PMID: 11602283]
  • H Masaki, T Atsumi, H Sakurai. Peroxyl radical scavenging activities of hamamelitannin in chemical and biological systems. Free radical research. 1995 May; 22(5):419-30. doi: 10.3109/10715769509147550. [PMID: 7633570]