Carboxyatractyloside (BioDeep_00000396458)

   

PANOMIX_OTCML-2023


代谢物信息卡片


dipotassium;(1R,4S,7S,9S,10S,13R,15S)-15-hydroxy-7-[(2R,3R,4R,5R,6R)-6-(hydroxymethyl)-3-(3-methylbutanoyloxy)-4,5-disulfooxyoxan-2-yl]oxy-9-methyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5,5-dicarboxylate

化学式: C31H44K2O18S2 (846.1243124)
中文名称: 胶苍术甙
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 10.53%

分子结构信息

SMILES: C=C([C@H](CC1)C2)[C@H](O)[C@@]32CC[C@]4([H])C(C(O)=O)(C(O)=O)C[C@@H](O[C@H]5[C@@H]([C@H]([C@@H]([C@@H](CO)O5)OS(=O)(O[K])=O)OS(=O)(O[K])=O)OC(CC(C)C)=O)C[C@@]4(C)[C@@]31[H]
InChI: /q

描述信息

Carboxyatractyloside dipotassium is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport[1].
Carboxyatractyloside dipotassium is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport[1].

同义名列表

15 个代谢物同义名

dipotassium;(1R,4S,7S,9S,10S,13R,15S)-15-hydroxy-7-[(2R,3R,4R,5R,6R)-6-(hydroxymethyl)-3-(3-methylbutanoyloxy)-4,5-disulfooxyoxan-2-yl]oxy-9-methyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5,5-dicarboxylate; Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-((2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl)oxy)-, dipotassium salt, (2-beta,15-alpha)-; kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-((2-o-(3-methyl-1-oxobutyl)-3,4-di-o-sulfo-beta-D-glucopyranosyl)oxy)-, dipotassium salt, (2beta,15alpha)-; Carboxyatractyloside dipotassium salt; Carboxyatractyloside dipotassium; dipotassium carboxyatractyloside; potassium carboxyatractyloside; CAT dipotassium salt; Carboxyatractyloside; carboxyatractylate; UNII-SNP1XL23E6; SNP1XL23E6; gummiferin; Gummiferin (dipotassium); Carboxyatractyloside (dipotassium)



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Andrzej M Woyda-Ploszczyca. Direct and indirect targets of carboxyatractyloside, including overlooked toxicity toward nucleoside diphosphate kinase (NDPK) and mitochondrial H+ leak. Pharmaceutical biology. 2023 Dec; 61(1):372-390. doi: 10.1080/13880209.2023.2168704. [PMID: 36799406]
  • Hong Pan, Feng Yang, Daiyuan Xiang, Fuguo Shi. Simultaneous quantification of atractyloside and carboxyatractyloside in rat plasma by LC-MS/MS: Application to a pharmacokinetic study after oral administration of Xanthii Fructus extract. Journal of separation science. 2020 Feb; 43(3):590-597. doi: 10.1002/jssc.201900888. [PMID: 31701660]
  • Hai Jiang, Liu Yang, Xudong Xing, Meiling Yan, Xinyue Guo, Bingyou Yang, Qiu-Hong Wang, Hai-Xue Kuang. Chemometrics coupled with UPLC-MS/MS for simultaneous analysis of markers in the raw and processed Fructus Xanthii, and application to optimization of processing method by BBD design. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2019 Apr; 57(?):191-202. doi: 10.1016/j.phymed.2018.12.020. [PMID: 30776590]
  • Kelly C S Godoy, Paula V Leal, Marcelo A Araújo, Alda I Souza, Arnildo Pott, Stephen T Lee, Claudio S L Barros, Ricardo A A de Lemos. Experimental poisoning by Vernonia rubricaulis in sheep. Toxicon : official journal of the International Society on Toxinology. 2018 Jan; 141(?):9-14. doi: 10.1016/j.toxicon.2017.11.002. [PMID: 29128544]
  • Joonseok Cho, Yujian Zhang, Shi-Young Park, Anna-Maria Joseph, Chul Han, Hyo-Jin Park, Srilaxmi Kalavalapalli, Sung-Kook Chun, Drake Morgan, Jae-Sung Kim, Shinichi Someya, Clayton E Mathews, Young Jae Lee, Stephanie E Wohlgemuth, Nishanth E Sunny, Hui-Young Lee, Cheol Soo Choi, Takayuki Shiratsuchi, S Paul Oh, Naohiro Terada. Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance. Nature communications. 2017 02; 8(?):14477. doi: 10.1038/ncomms14477. [PMID: 28205519]
  • Stefanie Nikles, Heidi Heuberger, Eberhard Hilsdorf, Robert Schmücker, Rebecca Seidenberger, Rudolf Bauer. Influence of Processing on the Content of Toxic Carboxyatractyloside and Atractyloside and the Microbiological Status of Xanthium sibiricum Fruits (Cang'erzi). Planta medica. 2015 Aug; 81(12-13):1213-20. doi: 10.1055/s-0035-1546207. [PMID: 26287695]
  • Jérémy Carlier, Ludovic Romeuf, Jérôme Guitton, Cédric Priez-Barallon, Fabien Bévalot, Laurent Fanton, Yvan Gaillard. A validated method for quantifying atractyloside and carboxyatractyloside in blood by HPLC-HRMS/MS, a non-fatal case of intoxication with Atractylis gummifera L. Journal of analytical toxicology. 2014 Nov; 38(9):619-27. doi: 10.1093/jat/bku078. [PMID: 24990875]
  • Christo J Botha, Dries Lessing, Magda Rösemann, Erna van Wilpe, June H Williams. Analytical confirmation of Xanthium strumarium poisoning in cattle. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 2014 Sep; 26(5):640-5. doi: 10.1177/1040638714542867. [PMID: 25012081]
  • Ching-Hsueh Cheng, Han-Chen Lin, I-Rue Lai, Hong-Shiee Lai. Ischemic postconditioning attenuate reperfusion injury of small intestine: impact of mitochondrial permeability transition. Transplantation. 2013 Feb; 95(4):559-65. doi: 10.1097/tp.0b013e31827e6b02. [PMID: 23423267]
  • Yang Wang, Ting Han, Li-Ming Xue, Ping Han, Qiao-Yan Zhang, Bao-Kang Huang, Hong Zhang, Qian-Liang Ming, Wei Peng, Lu-Ping Qin. Hepatotoxicity of kaurene glycosides from Xanthium strumarium L. fruits in mice. Die Pharmazie. 2011 Jun; 66(6):445-9. doi: NULL. [PMID: 21699085]
  • Enara Aguirre, Susana Cadenas. GDP and carboxyatractylate inhibit 4-hydroxynonenal-activated proton conductance to differing degrees in mitochondria from skeletal muscle and heart. Biochimica et biophysica acta. 2010 Oct; 1797(10):1716-26. doi: 10.1016/j.bbabio.2010.06.009. [PMID: 20599679]
  • Noemí García, Cecilia Zazueta, Mohammed El-Hafidi, Natalia Pavón, Eduardo Martínez-Abundis, Luz Hernández-Esquivel, Edmundo Chávez. Cyclosporin A inhibits UV-radiation-induced membrane damage but is unable to inhibit carboxyatractyloside-induced permeability transition. Radiation research. 2009 Nov; 172(5):575-83. doi: 10.1667/rr1799.1. [PMID: 19883225]
  • Martin Jastroch, Kerry W Withers, Sigrid Stoehr, Martin Klingenspor. Mitochondrial proton conductance in skeletal muscle of a cold-exposed marsupial, Antechinus flavipes, is unlikely to be involved in adaptive nonshivering thermogenesis but displays increased sensitivity toward carbon-centered radicals. Physiological and biochemical zoology : PBZ. 2009 Sep; 82(5):447-54. doi: 10.1086/603631. [PMID: 19614545]
  • Cláudia V Pereira, Nuno G Machado, Paulo J Oliveira. Mechanisms of berberine (natural yellow 18)-induced mitochondrial dysfunction: interaction with the adenine nucleotide translocator. Toxicological sciences : an official journal of the Society of Toxicology. 2008 Oct; 105(2):408-17. doi: 10.1093/toxsci/kfn131. [PMID: 18599498]
  • Jennifer M Johnston, Syma Khalid, Mark S P Sansom. Conformational dynamics of the mitochondrial ADP/ATP carrier: a simulation study. Molecular membrane biology. 2008 Sep; 25(6-7):506-17. doi: 10.1080/09687680802459271. [PMID: 18988066]
  • V N Samartsev, O V Kozhina. Oxidative stress as regulatory factor for fatty-acid-induced uncoupling involving liver mitochondrial ADP/ATP and aspartate/glutamate antiporters of old rats. Biochemistry. Biokhimiia. 2008 Jul; 73(7):783-90. doi: 10.1134/s0006297908070067. [PMID: 18707586]
  • Nadeene Parker, Charles Affourtit, Antonio Vidal-Puig, Martin D Brand. Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria. The Biochemical journal. 2008 May; 412(1):131-9. doi: 10.1042/bj20080006. [PMID: 18251717]
  • Lubica Malekova, Viera Kominkova, Miroslav Ferko, Peter Stefanik, Olga Krizanova, Attila Ziegelhöffer, Adam Szewczyk, Karol Ondrias. Bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart. Biochimica et biophysica acta. 2007 Jan; 1767(1):31-44. doi: 10.1016/j.bbabio.2006.10.004. [PMID: 17123460]
  • Lyudmila S Khailova, Elena A Prikhodko, Vera I Dedukhova, Elena N Mokhova, Vasily N Popov, Vladimir P Skulachev. Participation of ATP/ADP antiporter in oleate- and oleate hydroperoxide-induced uncoupling suppressed by GDP and carboxyatractylate. Biochimica et biophysica acta. 2006 Sep; 1757(9-10):1324-9. doi: 10.1016/j.bbabio.2006.04.024. [PMID: 16765906]
  • Noemí García, Eduardo Martínez-Abundis, Natalia Pavón, Edmundo Chávez. Sodium inhibits permeability transition by decreasing potassium matrix content in rat kidney mitochondria. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2006 Aug; 144(4):442-50. doi: 10.1016/j.cbpb.2006.04.002. [PMID: 16762575]
  • Daniela Trono, Mario Soccio, Anna M Mastrangelo, Vanessa De Simone, Natale Di Fonzo, Donato Pastore. The transcript levels of two plant mitochondrial uncoupling protein (pUCP)-related genes are not affected by hyperosmotic stress in durum wheat seedlings showing an increased level of pUCP activity. Bioscience reports. 2006 Jun; 26(3):251-61. doi: 10.1007/s10540-006-9020-1. [PMID: 16855867]
  • Tatiana Brustovetsky, Natalia Shalbuyeva, Nickolay Brustovetsky. Lack of manifestations of diazoxide/5-hydroxydecanoate-sensitive KATP channel in rat brain nonsynaptosomal mitochondria. The Journal of physiology. 2005 Oct; 568(Pt 1):47-59. doi: 10.1113/jphysiol.2005.091199. [PMID: 16051627]
  • Edmundo Chávez, José S Rodríguez, Gerardo García, Noemí García, Francisco Correa. Oligomycin strengthens the effect of cyclosporin A on mitochondrial permeability transition by inducing phosphate uptake. Cell biology international. 2005 Jul; 29(7):551-8. doi: 10.1016/j.cellbi.2005.03.009. [PMID: 15979905]
  • Mehmet Turgut, Cafer Cumhur Alhan, Metin Gürgöze, Abdullah Kurt, Yaşar Doğan, Muhittin Tekatli, Nusret Akpolat, A Denizmen Aygün. Carboxyatractyloside poisoning in humans. Annals of tropical paediatrics. 2005 Jun; 25(2):125-34. doi: 10.1179/146532805x45728. [PMID: 15949201]
  • C Daniele, S Dahamna, O Firuzi, N Sekfali, L Saso, G Mazzanti. Atractylis gummifera L. poisoning: an ethnopharmacological review. Journal of ethnopharmacology. 2005 Feb; 97(2):175-81. doi: 10.1016/j.jep.2004.11.025. [PMID: 15707749]
  • Luciane C Alberici, Helena C F Oliveira, Eliete J B Bighetti, Eliana C de Faria, Giovana R Degaspari, Claudio T Souza, Anibal E Vercesi. Hypertriglyceridemia increases mitochondrial resting respiration and susceptibility to permeability transition. Journal of bioenergetics and biomembranes. 2003 Oct; 35(5):451-7. doi: 10.1023/a:1027343915452. [PMID: 14740893]
  • Karim S Echtay, Telma C Esteves, Julian L Pakay, Mika B Jekabsons, Adrian J Lambert, Manuel Portero-Otín, Reinald Pamplona, Antonio J Vidal-Puig, Steven Wang, Stephen J Roebuck, Martin D Brand. A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling. The EMBO journal. 2003 Aug; 22(16):4103-10. doi: 10.1093/emboj/cdg412. [PMID: 12912909]
  • Susanna Iossa, Maria Pia Mollica, Lillà Lionetti, Raffaella Crescenzo, Monica Botta, Giovanna Liverini. Metabolic efficiency of liver mitochondria in rats with decreased thermogenesis. FEBS letters. 2003 Jun; 544(1-3):133-7. doi: 10.1016/s0014-5793(03)00490-3. [PMID: 12782303]
  • Edmundo Chávez, Cecilia Zazueta, Francisco Correa, Noemí García, César Avilés, Sandra G Robles, César D Rodríguez. Modulation by substrates of the protective effect of cyclosporin A on mitochondrial damage. Life sciences. 2002 Apr; 70(20):2413-20. doi: 10.1016/s0024-3205(02)01486-8. [PMID: 12150205]
  • V N Popov, O V Markova, E N Mokhova, V P Skulachev. Effects of cold exposure in vivo and uncouplers and recouplers in vitro on potato tuber mitochondria. Biochimica et biophysica acta. 2002 Feb; 1553(3):232-7. doi: 10.1016/s0005-2728(01)00244-4. [PMID: 11997132]
  • V A Lórenz, J Villaverde, V Trézéguet, G J Lauquin, G Brandolin, E Padrós. The secondary structure of the inhibited mitochondrial ADP/ATP transporter from yeast analyzed by FTIR spectroscopy. Biochemistry. 2001 Jul; 40(30):8821-33. doi: 10.1021/bi010091s. [PMID: 11467943]
  • N García, C Zazueta, R Carrillo, F Correa, E Chávez. Copper sensitizes the mitochondrial permeability transition to carboxytractyloside and oleate. Molecular and cellular biochemistry. 2000 Jun; 209(1-2):119-23. doi: 10.1023/a:1007151511817. [PMID: 10942209]
  • V Casolo, E Braidot, E Chiandussi, F Macrì, A Vianello. The role of mild uncoupling and non-coupled respiration in the regulation of hydrogen peroxide generation by plant mitochondria. FEBS letters. 2000 May; 474(1):53-7. doi: 10.1016/s0014-5793(00)01576-3. [PMID: 10828450]
  • M Bof, G Brandolin, M Satre, G Klein. The mitochondrial adenine nucleotide translocator from Dictyostelium discoideum. Functional characterization and DNA sequencing. European journal of biochemistry. 1999 Feb; 259(3):795-800. doi: 10.1046/j.1432-1327.1999.00088.x. [PMID: 10092866]
  • R A Simonyan, V P Skulachev. Thermoregulatory uncoupling in heart muscle mitochondria: involvement of the ATP/ADP antiporter and uncoupling protein. FEBS letters. 1998 Sep; 436(1):81-4. doi: 10.1016/s0014-5793(98)01106-5. [PMID: 9771898]
  • E E Saviani, I S Martins. Fatty acid-mediated uncoupling of potato tuber mitochondria. Biochemistry and molecular biology international. 1998 Apr; 44(4):833-9. doi: 10.1080/15216549800201882. [PMID: 9584997]
  • N Broustovetsky, E Bamberg, T Gropp, M Klingenberg. Biochemical and physical parameters of the electrical currents measured with the ADP/ATP carrier by photolysis of caged ADP and ATP. Biochemistry. 1997 Nov; 36(45):13865-72. doi: 10.1021/bi971578x. [PMID: 9374864]
  • C Bravo, E Chávez, J S Rodríguez, R Moreno-Sánchez. The mitochondrial membrane permeability transition induced by inorganic phosphate or inorganic arsenate. A comparative study. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 1997 May; 117(1):93-9. doi: 10.1016/s0305-0491(96)00257-x. [PMID: 9180017]
  • M R Wieckowski, L Wojtczak. Involvement of the dicarboxylate carrier in the protonophoric action of long-chain fatty acids in mitochondria. Biochemical and biophysical research communications. 1997 Mar; 232(2):414-7. doi: 10.1006/bbrc.1997.6298. [PMID: 9125192]
  • H E Neuhaus, E Thom, T Möhlmann, M Steup, K Kampfenkel. Characterization of a novel eukaryotic ATP/ADP translocator located in the plastid envelope of Arabidopsis thaliana L. The Plant journal : for cell and molecular biology. 1997 Jan; 11(1):73-82. doi: 10.1046/j.1365-313x.1997.11010073.x. [PMID: 9025303]
  • J Girón-Calle, H H Schmid. Peroxidative modification of a membrane protein. Conformation-dependent chemical modification of adenine nucleotide translocase in Cu2+/tert-butyl hydroperoxide treated mitochondria. Biochemistry. 1996 Dec; 35(48):15440-6. doi: 10.1021/bi960840j. [PMID: 8952497]
  • F Beauseigneur, M Goubern, M F Chapey, J Gresti, C Vergely, M Tsoko, J Demarquoy, L Rochette, P Clouet. F1F0-ATPase, early target of the radical initiator 2,2'-azobis-(2-amidinopropane) dihydrochloride in rat liver mitochondria in vitro. The Biochemical journal. 1996 Dec; 320 ( Pt 2)(?):571-6. doi: 10.1042/bj3200571. [PMID: 8973568]
  • F Macri, A Vianello, E Braidot, E Petrussa, E N Mokhova. Zearalenone-induced uncoupling in plant mitochondria is sensitive to 6-ketocholestanol. Biochemistry and molecular biology international. 1996 Aug; 39(5):1001-6. doi: 10.1080/15216549600201152. [PMID: 8866017]
  • T A Lohret, R C Murphy, T Drgoñ, K W Kinnally. Activity of the mitochondrial multiple conductance channel is independent of the adenine nucleotide translocator. The Journal of biological chemistry. 1996 Mar; 271(9):4846-9. doi: 10.1074/jbc.271.9.4846. [PMID: 8617754]
  • E Chávez, R Moreno-Sánchez, C Zazueta, A Cuéllar, J Ramirez, H Reyes-Vivas, C Bravo, S Rodríguez-Enríquez. On the mechanism by which 6-ketocholestanol protects mitochondria against uncoupling-induced Ca2+ efflux. FEBS letters. 1996 Feb; 379(3):305-8. doi: 10.1016/0014-5793(95)01533-7. [PMID: 8603712]
  • E Chávez, R Moreno-Sánchez, M E Torres-Marquez, C Zazueta, C Bravo, S Rodríquez-Enríquez, C García, J S Rodriguez, F Martinez. Modulation of matrix Ca2+ content by the ADP/ATP carrier in brown adipose tissue mitochondria. Influence of membrane lipid composition. Journal of bioenergetics and biomembranes. 1996 Feb; 28(1):69-76. doi: 10.1007/bf02150680. [PMID: 8786240]
  • N Brustovetsky, A Becker, M Klingenberg, E Bamberg. Electrical currents associated with nucleotide transport by the reconstituted mitochondrial ADP/ATP carrier. Proceedings of the National Academy of Sciences of the United States of America. 1996 Jan; 93(2):664-8. doi: 10.1073/pnas.93.2.664. [PMID: 8570612]
  • F Macri, A Vianello, E Petrussa, E Mokhova. Effect of carboxyatractylate on transmembrane electrical potential of plant mitochondria in different metabolic states. Biochemistry and molecular biology international. 1994 Sep; 34(2):217-24. doi: ". [PMID: 7849631]
  • E Roeder, T Bourauel, U Meier, H Wiedenfeld. Diterpene glycosides from Iphiona aucheri. Phytochemistry. 1994 Sep; 37(2):353-5. doi: 10.1016/0031-9422(94)85060-7. [PMID: 7765618]
  • A Vianello, E Petrussa, F Macrì. ATP/ADP antiporter is involved in uncoupling of plant mitochondria induced by low concentrations of palmitate. FEBS letters. 1994 Aug; 349(3):407-10. doi: 10.1016/0014-5793(94)00712-8. [PMID: 8050605]
  • G Paradies, F M Ruggiero, G Petrosillo, M N Gadaleta, E Quagliariello. The effect of aging and acetyl-L-carnitine on the function and on the lipid composition of rat heart mitochondria. Annals of the New York Academy of Sciences. 1994 Jun; 717(?):233-43. doi: 10.1111/j.1749-6632.1994.tb12093.x. [PMID: 8030840]
  • A Vianello, E Petrussa, F Macrì. ATP/ADP antiporter is involved in uncoupling of plant mitochondria induced by low concentrations of palmitate. FEBS letters. 1994 Jun; 347(2-3):239-42. doi: 10.1016/0014-5793(94)00540-0. [PMID: 7986263]
  • D V de Macedo, M E Nepomuceno, L Pereira-da-Silva. Involvement of the ADP/ATP carrier in permeabilization processes of the inner mitochondrial membrane. European journal of biochemistry. 1993 Aug; 215(3):595-600. doi: 10.1111/j.1432-1033.1993.tb18070.x. [PMID: 8354266]
  • T Hagen, J L Joyal, W Henke, J R Aprille. Net adenine nucleotide transport in rat kidney mitochondria. Archives of biochemistry and biophysics. 1993 Jun; 303(2):195-207. doi: 10.1006/abbi.1993.1273. [PMID: 8512308]
  • J Streicher-Scott, R Lapidus, P M Sokolove. Use of carboxyatractylate and tight-binding inhibitor theory to determine the concentration of functional mitochondrial adenine nucleotide translocators in a reconstituted system. Analytical biochemistry. 1993 Apr; 210(1):69-76. doi: 10.1006/abio.1993.1152. [PMID: 8489026]
  • N N Brustovetsky, M V Egorova, Gnutov DYu, V G Gogvadze, E N Mokhova, V P Skulachev. Thermoregulatory, carboxyatractylate-sensitive uncoupling in heart and skeletal muscle mitochondria of the ground squirrel correlates with the level of free fatty acids. FEBS letters. 1992 Jun; 305(1):15-7. doi: 10.1016/0014-5793(92)80645-w. [PMID: 1633854]
  • R B Gregory, M N Berry. Stimulation by thyroid hormone of coupled respiration and of respiration apparently not coupled to the synthesis of ATP in rat hepatocytes. The Journal of biological chemistry. 1992 May; 267(13):8903-8. doi: 10.1016/s0021-9258(19)50365-9. [PMID: 1577728]
  • C W Zwizinski, H H Schmid. Peroxidative damage to cardiac mitochondria: identification and purification of modified adenine nucleotide translocase. Archives of biochemistry and biophysics. 1992 Apr; 294(1):178-83. doi: 10.1016/0003-9861(92)90154-o. [PMID: 1550344]
  • M E Krejci, D A Koechel. Acute effects of carboxyatractyloside and stevioside, inhibitors of mitochondrial ADP/ATP translocation, on renal function and ultrastructure in pentobarbital-anesthetized dogs. Toxicology. 1992; 72(3):299-313. doi: 10.1016/0300-483x(92)90181-d. [PMID: 1585384]
  • E Chávez, R Moreno-Sánchez, C Zazueta, H Reyes-Vivas, D Arteaga. Intramitochondrial K+ as activator of carboxyatractyloside-induced Ca2+ release. Biochimica et biophysica acta. 1991 Dec; 1070(2):461-6. doi: 10.1016/0005-2736(91)90087-o. [PMID: 1764458]
  • N N Brustovetskiĭ, Z G Amerkhanov, M V Egorova, E N Mokhova, V P Skulachev. [Participation of the ATP/ADP antiporter and fatty acids in oxidative phosphorylation uncoupling in squirrel liver mitochondria during winter hibernation and awakening]. Biokhimiia (Moscow, Russia). 1991 May; 56(5):947-53. doi: NULL. [PMID: 1747420]
  • K Bücheler, V Adams, D Brdiczka. Localization of the ATP/ADP translocator in the inner membrane and regulation of contact sites between mitochondrial envelope membranes by ADP. A study on freeze-fractured isolated liver mitochondria. Biochimica et biophysica acta. 1991 Feb; 1056(3):233-42. doi: 10.1016/s0005-2728(05)80054-4. [PMID: 1825787]
  • N N Brustovetsky, Z G Amerkanov, M E Yegorova, E N Mokhova, V P Skulachev. Carboxyatractylate-sensitive uncoupling in liver mitochondria from ground squirrels during hibernation and arousal. FEBS letters. 1990 Oct; 272(1-2):190-2. doi: 10.1016/0014-5793(90)80481-w. [PMID: 2226831]
  • S T Witte, G D Osweiler, H M Stahr, G Mobley. Cocklebur toxicosis in cattle associated with the consumption of mature Xanthium strumarium. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 1990 Oct; 2(4):263-7. doi: 10.1177/104063879000200402. [PMID: 2095279]
  • P Schönfeld. Does the function of adenine nucleotide translocase in fatty acid uncoupling depend on the type of mitochondria?. FEBS letters. 1990 May; 264(2):246-8. doi: 10.1016/0014-5793(90)80259-l. [PMID: 2162786]
  • P Schönfeld, L Schild, W Kunz. Long-chain fatty acids act as protonophoric uncouplers of oxidative phosphorylation in rat liver mitochondria. Biochimica et biophysica acta. 1989 Dec; 977(3):266-72. doi: 10.1016/s0005-2728(89)80080-5. [PMID: 2556180]
  • L I Horváth, A Munding, K Beyer, M Klingenberg, D Marsh. Rotational diffusion of mitochondrial ADP/ATP carrier studied by saturation-transfer electron spin resonance. Biochemistry. 1989 Jan; 28(1):407-14. doi: 10.1021/bi00427a056. [PMID: 2539863]
  • M Ziegler, W Dubiel, W Henke, K Jung, A M Pimenov, Tikhonov YuV, R T Togusov, G Gerber. The adenine nucleotide catabolism in nonphosphorylating mitochondria of different tissues. Biomedica biochimica acta. 1989; 48(2-3):S48-52. doi: NULL. [PMID: 2730629]
  • L S Tisa, J C Ensign. Evidence for adenylate nucleotide transport (ATP-ADP translocation) in vesicles of Frankia sp. strain EAN1pec. Journal of bacteriology. 1988 Jul; 170(7):3053-7. doi: 10.1128/jb.170.7.3053-3057.1988. [PMID: 3164310]
  • T Martin, E L Stair, L Dawson. Cocklebur poisoning in cattle. Journal of the American Veterinary Medical Association. 1986 Sep; 189(5):562-3. doi: ". [PMID: 3759629]
  • M E Martens, C H Chang, C P Lee. Reye's syndrome: mitochondrial swelling and Ca2+ release induced by Reye's plasma, allantoin, and salicylate. Archives of biochemistry and biophysics. 1986 Feb; 244(2):773-86. doi: 10.1016/0003-9861(86)90646-6. [PMID: 3080954]
  • G Woldegiorgis, S Voss, E Shrago, M Werner-Washburne, K Keegstra. Adenine nucleotide translocase-dependent anion transport in pea chloroplasts. Biochimica et biophysica acta. 1985 Dec; 810(3):340-5. doi: 10.1016/0005-2728(85)90219-1. [PMID: 2998460]
  • R C Hatch, A V Jain, R Weiss, J D Clark. Toxicologic study of carboxyatractyloside (active principle in cocklebur--Xanthium strumarium) in rats treated with enzyme inducers and inhibitors and glutathione precursor and depletor. American journal of veterinary research. 1982 Jan; 43(1):111-6. doi: NULL. [PMID: 7091806]
  • B P Stuart, R J Cole, H S Gosser. Cocklebur (Xanthium strumarium, L. var. strumarium) intoxication in swine: review and redefinition of the toxic principle. Veterinary pathology. 1981 May; 18(3):368-83. doi: 10.1177/030098588101800310. [PMID: 7257080]
  • G Brandolin, J Doussiere, A Gulik, T Gulik-Krzywicki, G J Lauquin, P V Vignais. Kinetic, binding and ultrastructural properties of the beef heart adenine nucleotide carrier protein after incorporation into phospholipid vesicles. Biochimica et biophysica acta. 1980 Oct; 592(3):592-614. doi: 10.1016/0005-2728(80)90103-6. [PMID: 6251872]
  • P V Vignais, P M Vignais, G Defaye. Adenosine diphosphate translocation in mitochondria. Nature of the receptor site for carboxyatractyloside (gummiferin). Biochemistry. 1973 Apr; 12(8):1508-19. doi: 10.1021/bi00732a007. [PMID: 4699983]