MK2IXH6AUE (BioDeep_00000396377)

 

Secondary id: BioDeep_00000249190

PANOMIX_OTCML-2023


代谢物信息卡片


9,10-Anthracenedione, 3-hydroxy-1-methoxy-2-methyl-

化学式: C16H12O4 (268.0735552)
中文名称: 甲基异茜草素-1-甲醚, 3-羟基-1-甲氧基-2-甲基蒽醌
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(C=C2C(=C1OC)C(=O)C3=CC=CC=C3C2=O)O
InChI: InChI=1S/C16H12O4/c1-8-12(17)7-11-13(16(8)20-2)15(19)10-6-4-3-5-9(10)14(11)18/h3-7,17H,1-2H3

描述信息

Rubiadin 1-methyl ether is a natural product found in Prismatomeris tetrandra, Coprosma areolata, and other organisms with data available.
Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65[1].
Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65[1].

同义名列表

13 个代谢物同义名

9,10-Anthracenedione, 3-hydroxy-1-methoxy-2-methyl-; 3-hydroxy-1-methoxy-2-methyl-anthracene-9,10-dione; 3-hydroxy-1-methoxy-2-methylanthracene-9,10-dione; 3-HYDROXY-1-METHOXY-2-METHYL-9,10-ANTHRACENEDIONE; ANTHRAQUINONE, 3-HYDROXY-1-METHOXY-2-METHYL-; 3-Hydroxy-1-methoxy-2-methyl-anthraquinone; 1-Methoxy-2-methyl-3-hydroxy-anthrachinon; 3-Hydroxy-1-methoxy-2-methylanthraquinone; Rubiadin-1-methyl ether; Rubiadin 1-methyl ether; UNII-MK2IXH6AUE; NCIOpen2_002551; MK2IXH6AUE



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Phi-Hung Nguyen, Hong Seok Choi, Thi Kim Quy Ha, Ji Yeon Seo, Jun-Li Yang, Da-Woon Jung, Darren R Williams, Won-Keun Oh. Anthraquinones from Morinda longissima and their insulin mimetic activities via AMP-activated protein kinase (AMPK) activation. Bioorganic & medicinal chemistry letters. 2017 01; 27(1):40-44. doi: 10.1016/j.bmcl.2016.11.034. [PMID: 27887844]
  • Negera Abdissa, Fangfang Pan, Amra Gruhonjic, Jürgen Gräfenstein, Paul A Fitzpatrick, Göran Landberg, Kari Rissanen, Abiy Yenesew, Máté Erdélyi. Naphthalene Derivatives from the Roots of Pentas parvifolia and Pentas bussei. Journal of natural products. 2016 09; 79(9):2181-7. doi: 10.1021/acs.jnatprod.6b00178. [PMID: 27518587]
  • Che Puteh Osman, Nor Hadiani Ismail, Rohaya Ahmad, Norizan Ahmat, Khalijah Awang, Faridahanim Mohd Jaafar. Anthraquinones with antiplasmodial activity from the roots of Rennellia elliptica Korth. (Rubiaceae). Molecules (Basel, Switzerland). 2010 Oct; 15(10):7218-26. doi: 10.3390/molecules15107218. [PMID: 20966871]
  • Pittaya Tuntiwachwuttikul, Yuttapon Butsuri, Piyanut Sukkoet, Uma Prawat, Walter Charles Taylor. Anthraquinones from the roots of Prismatomeris malayana. Natural product research. 2008; 22(11):962-8. doi: 10.1080/14786410701650261. [PMID: 18629711]
  • Jian-shuang Jiang, Zi-ming Feng, Pei-cheng Zhang. [Chemical constituents from root of Prismatomeris tetrandra]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2005 Nov; 30(22):1751-3. doi: . [PMID: 16468371]