Tea polyphenol (BioDeep_00000396374)

   

PANOMIX_OTCML-2023


代谢物信息卡片


5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate

化学式: C22H18O11 (458.0849078)
中文名称: 茶多酚
谱图信息: 最多检出来源 Astragalus membranaceus(otcml) 66.67%

分子结构信息

SMILES: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
InChI: InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2

描述信息

D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents
D020011 - Protective Agents > D016588 - Anticarcinogenic Agents
D020011 - Protective Agents > D016587 - Antimutagenic Agents
D020011 - Protective Agents > D000975 - Antioxidants
D000970 - Antineoplastic Agents

同义名列表

2 个代谢物同义名

5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate; Tea polyphenol



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ting Xiao, Mengqi Cui, Caijuan Zheng, Peipei Zhang, Shanfa Ren, Jiali Bao, Dandi Gao, Ronghao Sun, Ming Wang, Jianping Lin, Liang Zhang, Mingjiang Li, Dongmei Li, Honggang Zhou, Cheng Yang. Both Baicalein and Gallocatechin Gallate Effectively Inhibit SARS-CoV-2 Replication by Targeting Mpro and Sepsis in Mice. Inflammation. 2022 Jun; 45(3):1076-1088. doi: 10.1007/s10753-021-01602-z. [PMID: 34822072]
  • Ying-Qi Wang, Qing-Sheng Li, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang. Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19. Molecules (Basel, Switzerland). 2021 Jun; 26(13):. doi: 10.3390/molecules26133962. [PMID: 34209485]
  • Ming Zhao, Yu Yu, Li-Ming Sun, Jia-Qing Xing, Tingting Li, Yunkai Zhu, Miao Wang, Yin Yu, Wen Xue, Tian Xia, Hong Cai, Qiu-Ying Han, Xiaoyao Yin, Wei-Hua Li, Ai-Ling Li, Jiuwei Cui, Zhenghong Yuan, Rong Zhang, Tao Zhou, Xue-Min Zhang, Tao Li. GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein. Nature communications. 2021 04; 12(1):2114. doi: 10.1038/s41467-021-22297-8. [PMID: 33837182]
  • Navneet Kishore, Pradeep Kumar, Karuna Shanker, Akhilesh Kumar Verma. Human disorders associated with inflammation and the evolving role of natural products to overcome. European journal of medicinal chemistry. 2019 Oct; 179(?):272-309. doi: 10.1016/j.ejmech.2019.06.034. [PMID: 31255927]
  • Bihui Liu, Jing Zhang, Peng Sun, Ruokun Yi, Xiaoyan Han, Xin Zhao. Raw Bowl Tea (Tuocha) Polyphenol Prevention of Nonalcoholic Fatty Liver Disease by Regulating Intestinal Function in Mice. Biomolecules. 2019 09; 9(9):. doi: 10.3390/biom9090435. [PMID: 31480575]
  • Bo Chen, Jie Zhou, Qilu Meng, Yang Zhang, Shihua Zhang, Liang Zhang. Comparative analysis of fecal phenolic content between normal and obese rats after oral administration of tea polyphenols. Food & function. 2018 Sep; 9(9):4858-4864. doi: 10.1039/c8fo00609a. [PMID: 30156246]
  • Yunru Peng, Qilu Meng, Jie Zhou, Bo Chen, Junjun Xi, Piaopiao Long, Liang Zhang, Ruyan Hou. Nanoemulsion delivery system of tea polyphenols enhanced the bioavailability of catechins in rats. Food chemistry. 2018 Mar; 242(?):527-532. doi: 10.1016/j.foodchem.2017.09.094. [PMID: 29037724]
  • Cecília Rocha da Silva, João Batista de Andrade Neto, Rosana de Sousa Campos, Narjara Silvestre Figueiredo, Letícia Serpa Sampaio, Hemerson Iury Ferreira Magalhães, Bruno Coêlho Cavalcanti, Danielle Macêdo Gaspar, Geanne Matos de Andrade, Iri Sandro Pampolha Lima, Glauce Socorro de Barros Viana, Manoel Odorico de Moraes, Marina Duarte Pinto Lobo, Thalles Barbosa Grangeiro, Hélio Vitoriano Nobre Júnior. Synergistic effect of the flavonoid catechin, quercetin, or epigallocatechin gallate with fluconazole induces apoptosis in Candida tropicalis resistant to fluconazole. Antimicrobial agents and chemotherapy. 2014; 58(3):1468-78. doi: 10.1128/aac.00651-13. [PMID: 24366745]
  • Angelika S Rambold, Margit Miesbauer, Diana Olschewski, Ralf Seidel, Constanze Riemer, Lindsay Smale, Lisa Brumm, Michal Levy, Ehud Gazit, Dieter Oesterhelt, Michael Baier, Christian F W Becker, Martin Engelhard, Konstanze F Winklhofer, Jörg Tatzelt. Green tea extracts interfere with the stress-protective activity of PrP and the formation of PrP. Journal of neurochemistry. 2008 Oct; 107(1):218-29. doi: 10.1111/j.1471-4159.2008.05611.x. [PMID: 18691383]
  • Sang Min Lee, Chae Wook Kim, Jung Kee Kim, Hyun Jung Shin, Joo Hyun Baik. GCG-rich tea catechins are effective in lowering cholesterol and triglyceride concentrations in hyperlipidemic rats. Lipids. 2008 May; 43(5):419-29. doi: 10.1007/s11745-008-3167-4. [PMID: 18365267]
  • Akira Kotani, Kouji Takahashi, Hideki Hakamata, Satoshi Kojima, Fumiyo Kusu. Attomole catechins determination by capillary liquid chromatography with electrochemical detection. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2007 Feb; 23(2):157-63. doi: 10.2116/analsci.23.157. [PMID: 17297226]
  • B Yang, K Arai, F Kusu. Determination of catechins in human urine subsequent to tea ingestion by high-performance liquid chromatography with electrochemical detection. Analytical biochemistry. 2000 Jul; 283(1):77-82. doi: 10.1006/abio.2000.4624. [PMID: 10929811]