dracorhodin (BioDeep_00000395859)

   

PANOMIX_OTCML-2023


代谢物信息卡片


7-hydroxy-5-methoxy-6-methyl-2-phenyl-1-benzopyrylium, monoperchlorate

化学式: C17H15ClO7 (366.05062699999996)
中文名称: 血竭素高氯酸盐
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(C2=C(C=C1O)[O+]=C(C=C2)C3=CC=CC=C3)OC.[O-]Cl(=O)(=O)=O
InChI: (H,2,3,4,5)

描述信息

Dracorhodin perchlorate (Dracohodin perochlorate) is a natural product extracted from a natural medicine Dragon's blood. Dracorhodin perchlorate inhibits cell proliferation and induces cell cycle arrest and apoptosis[1][2].
Dracorhodin perchlorate (Dracohodin perochlorate) is a natural product extracted from a natural medicine Dragon's blood. Dracorhodin perchlorate inhibits cell proliferation and induces cell cycle arrest and apoptosis[1][2].

同义名列表

8 个代谢物同义名

7-hydroxy-5-methoxy-6-methyl-2-phenyl-1-benzopyrylium, monoperchlorate; 7-hydroxy-5-methoxy-6-methyl-2-phenylchromenylium perchlorate; 5-methoxy-6-methyl-2-phenylchromenylium-7-ol;perchlorate; 5-methoxy-6-methyl-2-phenyl-7H-1-benzopyran-7-one; Dracorhodin perochlorate; Dracohodin perochlorate; Dracorhodin perchlorate; dracorhodin



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Wendan Zhang, Honghong Jiang, Pengli Huang, Gaosong Wu, Qun Wang, Xin Luan, Hongwei Zhang, Dianping Yu, Hongru Wang, Dong Lu, Haonan Wang, Huazhang An, Sanhong Liu, Weidong Zhang. Dracorhodin targeting CMPK2 attenuates inflammation: A novel approach to sepsis therapy. Clinical and translational medicine. 2023 10; 13(10):e1449. doi: 10.1002/ctm2.1449. [PMID: 37859535]
  • Preethi Krishnaraj, Yu Chang, Tsung-Jung Ho, Nai-Chen Lu, Ming-Der Lin, Hao-Ping Chen. In vivo pro-angiogenic effects of dracorhodin perchlorate in zebrafish embryos: A novel bioactivity evaluation platform for commercial dragon blood samples. Journal of food and drug analysis. 2019 01; 27(1):259-265. doi: 10.1016/j.jfda.2018.08.005. [PMID: 30648579]
  • Xiaowen Jiang, Lin Liu, Lu Qiao, Binqing Zhang, Xuewei Wang, Yuwen Han, Wenhui Yu. Dracorhodin perchlorate regulates fibroblast proliferation to promote rat's wound healing. Journal of pharmacological sciences. 2018 Feb; 136(2):66-72. doi: 10.1016/j.jphs.2017.12.003. [PMID: 29428295]
  • Peihua Zhang, Jin Li, Xudong Tang, Junlei Zhang, Jie Liang, Guofang Zeng. Dracorhodin perchlorate induces apoptosis in primary fibroblasts from human skin hypertrophic scars via participation of caspase-3. European journal of pharmacology. 2014 Apr; 728(?):82-92. doi: 10.1016/j.ejphar.2014.01.068. [PMID: 24525335]
  • Qin Hu, E Sun, Feng-Juan Xu, Zhen-Hai Zhang, Xiao-Bin Jia. [Simultaneous content determination of notoginsenoside R1, ginsenoside Rg1, Re, Rb1 and dracorhodin in ZJHX rubber paste by double wavelength HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2013 Sep; 38(17):2793-7. doi: . [PMID: 24380300]
  • Yifeng Xie, Quansheng Wang, Jianguo Liu, Jiwen Xie, Kaming Xue, Qing Tang. [Dracorhodin perchlorate inhibit high glucose induce serum and glucocorticoid induced protein kinase 1 and fibronectin expression in human mesangial cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2010 Aug; 35(15):1996-2000. doi: 10.4268/cjcmm20101518. [PMID: 20931854]
  • Jianmei Shi, Ruilin Hu, Yanbin Lu, Cuirong Sun, Tianxing Wu. Single-step purification of dracorhodin from dragon's blood resin of Daemonorops draco using high-speed counter-current chromatography combined with pH modulation. Journal of separation science. 2009 Dec; 32(23-24):4040-7. doi: 10.1002/jssc.200900392. [PMID: 19877147]
  • M I Maguregui, R M Alonso, M Barandiaran, R M Jimenez, N García. Micellar electrokinetic chromatography method for the determination of several natural red dyestuff and lake pigments used in art work. Journal of chromatography. A. 2007 Jun; 1154(1-2):429-36. doi: 10.1016/j.chroma.2007.03.089. [PMID: 17452040]
  • S Liu, Z Li, G Qian. [Quantitative determination of dracorhodin in Daemonorops draco B1. and traditional Chinese medicines containing Daemonorops draco B1. by HPLC]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao. 1997 Dec; 28(4):450-3. doi: ". [PMID: 10683968]