Eburcoic acid (BioDeep_00000395578)

Main id: BioDeep_00000009936

 

PANOMIX_OTCML-2023


代谢物信息卡片


(r)-2-((3s,5r,10s,13r,14r,17r)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl)-6-methyl-5-methyleneheptanoic acid

化学式: C31H50O3 (470.37597500000004)
中文名称: 齿孔菌酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)C(=C)CCC(C1CCC2(C1(CCC3=C2CCC4C3(CCC(C4(C)C)O)C)C)C)C(=O)O
InChI: InChI=1S/C31H50O3/c1-19(2)20(3)9-10-21(27(33)34)22-13-17-31(8)24-11-12-25-28(4,5)26(32)15-16-29(25,6)23(24)14-18-30(22,31)7/h19,21-22,25-26,32H,3,9-18H2,1-2,4-8H3,(H,33,34)/t21-,22-,25+,26+,29-,30-,31+/m1/s1

描述信息

Eburicoic acid is a natural product found in Porotheleum, Taiwanofungus camphoratus, and other organisms with data available.
Eburicoic acid protects the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms[1]. And Eburicoic acid has antidiabetic and antihyperlipidemic effects[2].
Eburicoic acid protects the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms[1]. And Eburicoic acid has antidiabetic and antihyperlipidemic effects[2].

同义名列表

8 个代谢物同义名

(r)-2-((3s,5r,10s,13r,14r,17r)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl)-6-methyl-5-methyleneheptanoic acid; (2R)-2-[(3S,5S,10S,13R,14R,17R)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3 ,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-m ethyl-5-methylidene-heptanoic acid; Lanost-8-en-21-oic acid, 3-hydroxy-24-methylene-, (3beta)-; 3beta-Hydroxy-24-methylene-8-lanostene-21-oic acid; UNII-FE37KG6A7Q; Eburicoic acid; Eburcoic acid; FE37KG6A7Q



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Cheng-Hsiu Lin, Yueh-Hsiung Kuo, Chun-Ching Shih. Eburicoic Acid, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects in Palmitate-Treated C2C12 Myotubes and in High-Fat Diet-Fed Mice. International journal of molecular sciences. 2017 Nov; 18(11):. doi: 10.3390/ijms18112314. [PMID: 29099085]
  • Guan-Jhong Huang, Jeng-Shyan Deng, Shyh-Shyun Huang, Chao-Ying Lee, Wen-Chi Hou, Sheng-Yang Wang, Ping-Jyun Sung, Yueh-Hsiung Kuo. Hepatoprotective effects of eburicoic acid and dehydroeburicoic acid from Antrodia camphorata in a mouse model of acute hepatic injury. Food chemistry. 2013 Dec; 141(3):3020-7. doi: 10.1016/j.foodchem.2013.03.061. [PMID: 23871054]
  • Jeng-Shyan Deng, Shyh-Shyun Huang, Tsung-Hui Lin, Min-Min Lee, Ching-Chuan Kuo, Ping-Jyun Sung, Wen-Chi Hou, Guan-Jhong Huang, Yueh-Hsiung Kuo. Analgesic and anti-inflammatory bioactivities of eburicoic acid and dehydroeburicoic acid isolated from Antrodia camphorata on the inflammatory mediator expression in mice. Journal of agricultural and food chemistry. 2013 May; 61(21):5064-71. doi: 10.1021/jf303820k. [PMID: 23495748]
  • Bing-Ji Ma, Yuan Ruan. Trametes versatillis, a fungus highly producing eburicoic acid. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2007 Nov; 62(11-12):909-10. doi: 10.1515/znc-2007-11-1221. [PMID: 18274297]
  • Xueliang Fang, Lei Shao, Hui Zhang, Shaomeng Wang. CHMIS-C: a comprehensive herbal medicine information system for cancer. Journal of medicinal chemistry. 2005 Mar; 48(5):1481-8. doi: 10.1021/jm049838d. [PMID: 15743190]