5-Hydroxyoxindole (BioDeep_00000394640)

 

Secondary id: BioDeep_00000174719, BioDeep_00000860845

PANOMIX_OTCML-2023


代谢物信息卡片


2H-Indol-2-one, 1,3-dihydro-5-hydroxy-

化学式: C8H7NO2 (149.0476762)
中文名称: 5-羟基羟吲哚, 2-甲基-6-喹啉甲酸
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 8.16%

分子结构信息

SMILES: c1(ccc2c(c1)CC(=O)N2)O
InChI: InChI=1S/C8H7NO2/c10-6-1-2-7-5(3-6)4-8(11)9-7/h1-3,10H,4H2,(H,9,11)

描述信息

5-Hydroxyoxindole is a natural product found in Isatis tinctoria with data available.
5-Hydroxyoxindole is a structural analog of uric acid. 5-Hydroxyoxindole has DPPH radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders[1].
5-Hydroxyoxindole is a structural analog of uric acid. 5-Hydroxyoxindole has DPPH radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders[1].

同义名列表

16 个代谢物同义名

2H-Indol-2-one, 1,3-dihydro-5-hydroxy-; 5-Hydroxy-1,3-dihydro-2H-indol-2-one #; 5-Hydroxy-1,3-dihydro-2H-indol-2-one; 5-hydroxy-2,3-dihydro-1H-indol-2-one; 5-Hydroxy-1,3-dihydro-indol-2-one; 5-hydroxy-1,3-dihydroindol-2-one; 2,3-Dihydro-5-hydroxyindol-2-one; 5-hydroxyoxindole, AldrichCPR; 2-Indolinone, 5-hydroxy-; 5-Hydroxy-2-indolinone; 5-hydroxyindolin-2-one; 5-HYDROXY-2-OXYINDOLE; 5-Hydroxy-2-oxindole; 5-hydroxyindolinone; 5-hydroxy-oxindole; 5-Hydroxyoxindole



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Maninder Kaur, Manjinder Singh, Navriti Chadha, Om Silakari. Oxindole: A chemical prism carrying plethora of therapeutic benefits. European journal of medicinal chemistry. 2016 Nov; 123(?):858-894. doi: 10.1016/j.ejmech.2016.08.011. [PMID: 27543880]
  • Daisuke Yasuda, Kyoko Takahashi, Tomoyuki Ohe, Shigeo Nakamura, Tadahiko Mashino. Antioxidant activities of 5-hydroxyoxindole and its 3-hydroxy-3-phenacyl derivatives: the suppression of lipid peroxidation and intracellular oxidative stress. Bioorganic & medicinal chemistry. 2013 Dec; 21(24):7709-14. doi: 10.1016/j.bmc.2013.10.021. [PMID: 24216095]
  • Michèle Crumeyrolle-Arias, Marie-Claude Tournaire, Sylvie Rabot, Benoît Malpaux, Jean-Claude Thiéry. 5-hydroxyoxindole, an indole metabolite, is present at high concentrations in brain. Journal of neuroscience research. 2008 Jan; 86(1):202-7. doi: 10.1002/jnr.21475. [PMID: 17722070]