DAF-2 (BioDeep_00000392324)
代谢物信息卡片
化学式: C20H14N2O5 (362.0902674)
中文名称: 4,5-二氨基荧光黄
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC2=C(C=C1O)OC3=C(C24C5=CC(=C(C=C5C(=O)O4)N)N)C=CC(=C3)O
InChI: InChI=1S/C20H14N2O5/c21-15-7-11-14(8-16(15)22)20(27-19(11)25)12-3-1-9(23)5-17(12)26-18-6-10(24)2-4-13(18)20/h1-8,23-24H,21-22H2
描述信息
D004396 - Coloring Agents > D005456 - Fluorescent Dyes > D005452 - Fluoresceins
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Capilla Mata-Pérez, Beatriz Sánchez-Calvo, Juan C Begara-Morales, Alfonso Carreras, María N Padilla, Manuel Melguizo, Raquel Valderrama, Francisco J Corpas, Juan B Barroso. Nitro-linolenic acid is a nitric oxide donor.
Nitric oxide : biology and chemistry.
2016 07; 57(?):57-63. doi:
10.1016/j.niox.2016.05.003. [PMID: 27164295] - Adelaide Del Viscovo, Agnese Secondo, Alba Esposito, Fernando Goglia, Maria Moreno, Lorella M T Canzoniero. Intracellular and plasma membrane-initiated pathways involved in the [Ca2+]i elevations induced by iodothyronines (T3 and T2) in pituitary GH3 cells.
American journal of physiology. Endocrinology and metabolism.
2012 Jun; 302(11):E1419-30. doi:
10.1152/ajpendo.00389.2011. [PMID: 22414808] - Klaus Uhlenhut, Petra Högger. Pitfalls and limitations in using 4,5-diaminofluorescein for evaluating the influence of polyphenols on nitric oxide release from endothelial cells.
Free radical biology & medicine.
2012 Jun; 52(11-12):2266-75. doi:
10.1016/j.freeradbiomed.2012.03.006. [PMID: 22565032] - Emilia Bramanti, Valeria Angeli, Maria Franzini, Cecilia Vecoli, Riccardo Baldassini, Aldo Paolicchi, Renata Barsacchi, Alfonso Pompella. Exogenous vs. endogenous gamma-glutamyltransferase activity: Implications for the specific determination of S-nitrosoglutathione in biological samples.
Archives of biochemistry and biophysics.
2009 Jul; 487(2):146-52. doi:
10.1016/j.abb.2009.05.012. [PMID: 19467221] - Ruisheng Liu, Oscar A Carretero, YiLin Ren, Jeffrey L Garvin. Increased intracellular pH at the macula densa activates nNOS during tubuloglomerular feedback.
Kidney international.
2005 May; 67(5):1837-43. doi:
10.1111/j.1523-1755.2005.00282.x. [PMID: 15840031] - Eita Sasaki, Hirotatsu Kojima, Hiroaki Nishimatsu, Yasuteru Urano, Kazuya Kikuchi, Yasunobu Hirata, Tetsuo Nagano. Highly sensitive near-infrared fluorescent probes for nitric oxide and their application to isolated organs.
Journal of the American Chemical Society.
2005 Mar; 127(11):3684-5. doi:
10.1021/ja042967z. [PMID: 15771488] - Shaoyou Chu, H Glenn Bohlen. High concentration of glucose inhibits glomerular endothelial eNOS through a PKC mechanism.
American journal of physiology. Renal physiology.
2004 Sep; 287(3):F384-92. doi:
10.1152/ajprenal.00006.2004. [PMID: 15140758] - Peter Lorenz, Sanjoy Roychowdhury, Mario Engelmann, Gerald Wolf, Thomas F W Horn. Oxyresveratrol and resveratrol are potent antioxidants and free radical scavengers: effect on nitrosative and oxidative stress derived from microglial cells.
Nitric oxide : biology and chemistry.
2003 Sep; 9(2):64-76. doi:
10.1016/j.niox.2003.09.005. [PMID: 14623172] - Sergey V Brodsky, Shujuan Gao, Hong Li, Michael S Goligorsky. Hyperglycemic switch from mitochondrial nitric oxide to superoxide production in endothelial cells.
American journal of physiology. Heart and circulatory physiology.
2002 Nov; 283(5):H2130-9. doi:
10.1152/ajpheart.00196.2002. [PMID: 12384491] - K L Rhinehart, T L Pallone. Nitric oxide generation by isolated descending vasa recta.
American journal of physiology. Heart and circulatory physiology.
2001 Jul; 281(1):H316-24. doi:
10.1152/ajpheart.2001.281.1.h316. [PMID: 11406499] - M Broillet, O Randin, J Chatton. Photoactivation and calcium sensitivity of the fluorescent NO indicator 4,5-diaminofluorescein (DAF-2): implications for cellular NO imaging.
FEBS letters.
2001 Mar; 491(3):227-32. doi:
10.1016/s0014-5793(01)02206-2. [PMID: 11240132]