Thioridazine 5-Sulfoxide (BioDeep_00000391704)
代谢物信息卡片
化学式: C21H26N2OS2 (386.1486466)
中文名称:
谱图信息:
最多检出来源 Viridiplantae(plant) 95.24%
分子结构信息
SMILES: CN1CCCCC1CCN2C3=CC=CC=C3S(=O)C4=C2C=C(C=C4)SC
InChI: InChI=1S/C21H26N2OS2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)26(24)21-11-10-17(25-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3
数据库引用编号
5 个数据库交叉引用编号
- PubChem: 24494
- Metlin: METLIN2836
- ChEMBL: CHEMBL3544852
- CAS: 7776-05-8
- PMhub: MS000241926
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Cristiane Masetto de Gaitani, Alexandre Souto Martinez, Pierina Sueli Bonato. Study on thioridazine 5-sulfoxide epimerization and degradation by capillary electrophoresis.
Electrophoresis.
2003 Aug; 24(15):2723-30. doi:
10.1002/elps.200305480
. [PMID: 12900889] - W A Daniel, M Syrek, A Mach, J Wójcikowski, J Boksa. Pharmacokinetics of thioridazine and its metabolites in blood plasma and the brain of rats after acute and chronic treatment.
Polish journal of pharmacology.
1997 Nov; 49(6):439-52. doi:
NULL
. [PMID: 9566048] - C B Eap, T W Guentert, M Schãublin-Loidl, M Stabl, L Koeb, K Powell, P Baumann. Plasma levels of the enantiomers of thioridazine, thioridazine 2-sulfoxide, thioridazine 2-sulfone, and thioridazine 5-sulfoxide in poor and extensive metabolizers of dextromethorphan and mephenytoin.
Clinical pharmacology and therapeutics.
1996 Mar; 59(3):322-31. doi:
10.1016/s0009-9236(96)80010-5
. [PMID: 8653995] - C B Eap, A Souche, L Koeb, P Baumann. Light-induced racemization: artifacts in the analysis of the diastereoisomeric pairs of thioridazine 5-sulfoxide in the plasma and urine of patients treated with thioridazine.
Therapeutic drug monitoring.
1991 Jul; 13(4):356-62. doi:
. [PMID: 1780970]
- P W Hale, A Poklis. The biotransformation of thioridazine to thioridazine 5-sulfoxide stereoisomers in phenobarbital induced rats.
European journal of drug metabolism and pharmacokinetics.
1986 Oct; 11(4):283-9. doi:
10.1007/bf03189113
. [PMID: 3582423] - P W Hale, S Melethil, A Poklis. The disposition and elimination of stereoisomeric pairs of thioridazine 5-sulfoxide in the rat.
European journal of drug metabolism and pharmacokinetics.
1985 Oct; 10(4):333-41. doi:
10.1007/bf03189762
. [PMID: 3830721] - P W Hale, A Poklis. Thioridazine 5-sulfoxide diastereoisomers in serum and urine from rats and man after chronic thioridazine administration.
Journal of analytical toxicology.
1985 Sep; 9(5):197-201. doi:
10.1093/jat/9.5.197
. [PMID: 4057956] - A Heath, C Svensson, E Mårtensson. Thioridazine toxicity--an experimental cardiovascular study of thioridazine and its major metabolites in overdose.
Veterinary and human toxicology.
1985 Apr; 27(2):100-5. doi:
NULL
. [PMID: 3992882]