scriptaid (BioDeep_00000391209)
代谢物信息卡片
化学式: C18H18N2O4 (326.12665080000005)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCCCCC(=O)NO
InChI: InChI=1S/C18H18N2O4/c21-15(19-24)10-2-1-3-11-20-17(22)13-8-4-6-12-7-5-9-14(16(12)13)18(20)23/h4-9,24H,1-3,10-11H2,(H,19,21)
描述信息
D004791 - Enzyme Inhibitors > D056572 - Histone Deacetylase Inhibitors
同义名列表
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:92401
- PubChem: 5186
- Metlin: METLIN64766
- ChEMBL: CHEMBL96051
- CAS: 287383-59-9
- PMhub: MS000241396
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Rayan Awada, Dorothée Verdier, Solène Froger, Eric Brulard, Simone de Faria Maraschin, Hervé Etienne, David Breton. An innovative automated active compound screening system allows high-throughput optimization of somatic embryogenesis in Coffea arabica.
Scientific reports.
2020 01; 10(1):810. doi:
10.1038/s41598-020-57800-6. [PMID: 31965007] - Peng Hua, Barbara Kronsteiner, Mark van der Garde, Neil Ashley, Diana Hernandez, Marina Tarunina, Lilian Hook, Yen Choo, Irene Roberts, Adam Mead, Suzanne M Watt. Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion.
Scientific reports.
2019 03; 9(1):5300. doi:
10.1038/s41598-019-41803-z. [PMID: 30923342] - Ruosi Yao, Danyang Han, Xiaoyang Sun, Yu Xie, Qingyun Wu, Chunling Fu, Yao Yao, Hujun Li, Zhenyu Li, Kailin Xu. Scriptaid inhibits cell survival, cell cycle, and promotes apoptosis in multiple myeloma via epigenetic regulation of p21.
Experimental hematology.
2018 04; 60(?):63-72. doi:
10.1016/j.exphem.2017.12.012. [PMID: 29305109] - Vidhi Gaur, Timothy Connor, Kylie Venardos, Darren C Henstridge, Sheree D Martin, Courtney Swinton, Shona Morrison, Kathryn Aston-Mourney, Stefan M Gehrig, Roelof van Ewijk, Gordon S Lynch, Mark A Febbraio, Gregory R Steinberg, Mark Hargreaves, Ken R Walder, Sean L McGee. Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice.
Diabetes, obesity & metabolism.
2017 07; 19(7):936-943. doi:
10.1111/dom.12896. [PMID: 28155245] - Vidhi Gaur, Timothy Connor, Andrew Sanigorski, Sheree D Martin, Clinton R Bruce, Darren C Henstridge, Simon T Bond, Kevin A McEwen, Lyndal Kerr-Bayles, Trent D Ashton, Cassandra Fleming, Min Wu, Lisa S Pike Winer, Denise Chen, Gregg M Hudson, John W R Schwabe, Keith Baar, Mark A Febbraio, Paul Gregorevic, Frederick M Pfeffer, Ken R Walder, Mark Hargreaves, Sean L McGee. Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation.
Cell reports.
2016 09; 16(11):2802-2810. doi:
10.1016/j.celrep.2016.08.005. [PMID: 27626651] - Renfang Song, Thomas Van Buren, Ihor V Yosypiv. Histone deacetylases are critical regulators of the renin-angiotensin system during ureteric bud branching morphogenesis.
Pediatric research.
2010 Jun; 67(6):573-8. doi:
10.1203/pdr.0b013e3181da477c. [PMID: 20496471]