ciglitazone (BioDeep_00000389338)

   


代谢物信息卡片


5-[[4-[(1-methylcyclohexyl)methoxy]phenyl]methyl]-2,4-thiazolidinedione

化学式: C18H23NO3S (333.1398568)
中文名称: 酪里达唑
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1(CCCCC1)COC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
InChI: InChI=1S/C18H23NO3S/c1-18(9-3-2-4-10-18)12-22-14-7-5-13(6-8-14)11-15-16(20)19-17(21)23-15/h5-8,15H,2-4,9-12H2,1H3,(H,19,20,21)

描述信息

C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C98241 - Thiazolidinedione Antidiabetic Agent
D007004 - Hypoglycemic Agents

同义名列表

2 个代谢物同义名

ciglitazone; 5-[[4-[(1-methylcyclohexyl)methoxy]phenyl]methyl]-2,4-thiazolidinedione



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Xiang Z Li, Yan Yan, Jun F Zhang, Jian F Sun, Bin Sun, Chang G Yan, Seong H Choi, Bradley J Johnson, Jong K Kim, Stephen B Smith. Oleic acid in the absence of a PPARγ agonist increases adipogenic gene expression in bovine muscle satellite cells1. Journal of animal science. 2019 Oct; 97(10):4114-4123. doi: 10.1093/jas/skz269. [PMID: 31424542]
  • Camila Muñoz-Gutiérrez, Cesar Sepúlveda, Julio Caballero, Iván Palomo, Eduardo Fuentes. Study of the interactions between Edaglitazone and Ciglitazone with PPARγ and their antiplatelet profile. Life sciences. 2017 Oct; 186(?):59-65. doi: 10.1016/j.lfs.2017.07.031. [PMID: 28757415]
  • Beverly R Wuertz, Lindsay Darrah, Justin Wudel, Frank G Ondrey. Thiazolidinediones abrogate cervical cancer growth. Experimental cell research. 2017 04; 353(2):63-71. doi: 10.1016/j.yexcr.2017.02.020. [PMID: 28219679]
  • Simon K Wright, Beverly R Wuertz, George Harris, Raed Abu Ghazallah, Wendy A Miller, Patrick M Gaffney, Frank G Ondrey. Functional activation of PPARγ in human upper aerodigestive cancer cell lines. Molecular carcinogenesis. 2017 01; 56(1):149-162. doi: 10.1002/mc.22479. [PMID: 26999671]
  • Tomoyo Yoshinaga, Kenichiro Uwabe, Shoichi Naito, Kenichi Higashino, Toru Nakano, Yoshito Numata, Akio Kihara. AM251 Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells. PloS one. 2016; 11(12):e0167848. doi: 10.1371/journal.pone.0167848. [PMID: 27936102]
  • Leonie Wallmeyer, Dominika Lehnen, Natascha Eger, Michaela Sochorová, Lukáš Opálka, Andrej Kováčik, Kateřina Vávrová, Sarah Hedtrich. Stimulation of PPARα normalizes the skin lipid ratio and improves the skin barrier of normal and filaggrin deficient reconstructed skin. Journal of dermatological science. 2015 Nov; 80(2):102-10. doi: 10.1016/j.jdermsci.2015.09.012. [PMID: 26472199]
  • Kun He, Yue Li, Kang Yang, Jian-Ping Gong, Pei-Zhi Li. Effect of peroxisome proliferator-activated receptor γ on the cholesterol efflux of peritoneal macrophages in inflammation. Molecular medicine reports. 2014 Jul; 10(1):373-8. doi: 10.3892/mmr.2014.2200. [PMID: 24788275]
  • Swei Sunny Hann, Qing Tang, Fang Zheng, Shunyu Zhao, Jianping Chen, ZhiYu Wang. Repression of phosphoinositide-dependent protein kinase 1 expression by ciglitazone via Egr-1 represents a new approach for inhibition of lung cancer cell growth. Molecular cancer. 2014 Jun; 13(?):149. doi: 10.1186/1476-4598-13-149. [PMID: 24925061]
  • Mohammad Newaz, Zivar Yousefipour. PPARγ and NAD(P)H oxidase system interaction in glycerol-induced acute renal failure: role of gp91phox subunit of NAD(P)H oxidase. Renal failure. 2014 May; 36(4):567-74. doi: 10.3109/0886022x.2014.880323. [PMID: 24479849]
  • Ming Shan, Ran You, Xiaoyi Yuan, Michael V Frazier, Paul Porter, Alexander Seryshev, Jeong-Soo Hong, Li-zhen Song, Yiqun Zhang, Susan Hilsenbeck, Lawrence Whitehead, Nazanin Zarinkamar, Sarah Perusich, David B Corry, Farrah Kheradmand. Agonistic induction of PPARγ reverses cigarette smoke-induced emphysema. The Journal of clinical investigation. 2014 Mar; 124(3):1371-81. doi: 10.1172/jci70587. [PMID: 24569375]
  • Marlon R Schneider, Anastazia Samborski, Stefan Bauersachs, Christos C Zouboulis. Differentially regulated microRNAs during human sebaceous lipogenesis. Journal of dermatological science. 2013 May; 70(2):88-93. doi: 10.1016/j.jdermsci.2013.01.009. [PMID: 23452545]
  • Verena Paulitschke, Silke Gruber, Elisabeth Hofstätter, Verena Haudek-Prinz, Philipp Klepeisz, Nikolaus Schicher, Constanze Jonak, Peter Petzelbauer, Hubert Pehamberger, Christopher Gerner, Rainer Kunstfeld. Proteome analysis identified the PPARγ ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction. PloS one. 2012; 7(9):e46103. doi: 10.1371/journal.pone.0046103. [PMID: 23049949]
  • P R Tuinman, M C Gerards, G Jongsma, A P Vlaar, L Boon, N P Juffermans. Lack of evidence of CD40 ligand involvement in transfusion-related acute lung injury. Clinical and experimental immunology. 2011 Aug; 165(2):278-84. doi: 10.1111/j.1365-2249.2011.04422.x. [PMID: 21605114]
  • Radda Rusinova, Karl F Herold, R Lea Sanford, Denise V Greathouse, Hugh C Hemmings, Olaf S Andersen. Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery. The Journal of general physiology. 2011 Aug; 138(2):249-70. doi: 10.1085/jgp.201010529. [PMID: 21788612]
  • Zuzana Tobiasova, Lufeng Zhang, Tai Yi, Linfeng Qin, Thomas D Manes, Sanjay Kulkarni, Marc I Lorber, Frederick C Rodriguez, Je-Min Choi, George Tellides, Jordan S Pober, Ivana Kawikova, Alfred L M Bothwell. Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells. Circulation. 2011 Jul; 124(2):196-205. doi: 10.1161/circulationaha.110.015396. [PMID: 21690493]
  • Jun-Jie Wang, Oi-Tong Mak. Induction of apoptosis by 15d-PGJ2 via ROS formation: an alternative pathway without PPARγ activation in non-small cell lung carcinoma A549 cells. Prostaglandins & other lipid mediators. 2011 Apr; 94(3-4):104-11. doi: 10.1016/j.prostaglandins.2011.01.004. [PMID: 21396480]
  • Paras K Mishra, Neetu Tyagi, Utpal Sen, Irving G Joshua, Suresh C Tyagi. Synergism in hyperhomocysteinemia and diabetes: role of PPAR gamma and tempol. Cardiovascular diabetology. 2010 Sep; 9(?):49. doi: 10.1186/1475-2840-9-49. [PMID: 20828387]
  • Wei Su, Aijun Sun, Danling Xu, Hongqi Zhang, Lin Yang, Lingyan Yuan, Jianguo Jia, Yunzeng Zou, Yiling Wu, Keqiang Wang, Junbo Ge. Tongxinluo inhibits oxidized low-density lipoprotein-induced maturation of human dendritic cells via activating peroxisome proliferator-activated receptor gamma pathway. Journal of cardiovascular pharmacology. 2010 Aug; 56(2):177-83. doi: 10.1097/fjc.0b013e3181e5f0f8. [PMID: 20489656]
  • E Lord, E Bergeron, H Senta, H Park, N Faucheux. Effect of BMP-9 and its derived peptide on the differentiation of human white preadipocytes. Growth factors (Chur, Switzerland). 2010 Jun; 28(3):149-56. doi: 10.3109/08977190903512610. [PMID: 20102315]
  • Justine Y Lau, Brian G Oliver, Lyn M Moir, Judith L Black, Janette K Burgess. Differential expression of peroxisome proliferator activated receptor gamma and cyclin D1 does not affect proliferation of asthma- and non-asthma-derived airway smooth muscle cells. Respirology (Carlton, Vic.). 2010 Feb; 15(2):303-12. doi: 10.1111/j.1440-1843.2009.01683.x. [PMID: 20070588]
  • Basilia Zingarelli, Ranjit Chima, Michael O'Connor, Giovanna Piraino, Alvin Denenberg, Paul W Hake. Liver apoptosis is age dependent and is reduced by activation of peroxisome proliferator-activated receptor-gamma in hemorrhagic shock. American journal of physiology. Gastrointestinal and liver physiology. 2010 Jan; 298(1):G133-41. doi: 10.1152/ajpgi.00262.2009. [PMID: 19926821]
  • K Y Chung, B J Johnson. Melengestrol acetate enhances adipogenic gene expression in cultured muscle-derived cells. Journal of animal science. 2009 Dec; 87(12):3897-904. doi: 10.2527/jas.2008-1645. [PMID: 19684257]
  • B Chopra, N T Georgopoulos, A Nicholl, J Hinley, M B Oleksiewicz, J Southgate. Structurally diverse peroxisome proliferator-activated receptor agonists induce apoptosis in human uro-epithelial cells by a receptor-independent mechanism involving store-operated calcium channels. Cell proliferation. 2009 Oct; 42(5):688-700. doi: 10.1111/j.1365-2184.2009.00628.x. [PMID: 19614673]
  • Kyeongjin Kim, Kook Hwan Kim, Eunsin Ha, Jin Young Park, Naoya Sakamoto, Jaehun Cheong. Hepatitis C virus NS5A protein increases hepatic lipid accumulation via induction of activation and expression of PPARgamma. FEBS letters. 2009 Sep; 583(17):2720-6. doi: 10.1016/j.febslet.2009.07.034. [PMID: 19631645]
  • Marianne Demerjian, Eung-Ho Choi, Mao-Qiang Man, Sandra Chang, Peter M Elias, Kenneth R Feingold. Activators of PPARs and LXR decrease the adverse effects of exogenous glucocorticoids on the epidermis. Experimental dermatology. 2009 Jul; 18(7):643-9. doi: 10.1111/j.1600-0625.2009.00841.x. [PMID: 19236478]
  • Renata Grozovsky, Scott Ribich, Matthew L Rosene, Michelle A Mulcahey, Stephen A Huang, Mary Elizabeth Patti, Antonio C Bianco, Brian W Kim. Type 2 deiodinase expression is induced by peroxisomal proliferator-activated receptor-gamma agonists in skeletal myocytes. Endocrinology. 2009 Apr; 150(4):1976-83. doi: 10.1210/en.2008-0938. [PMID: 19036883]
  • Sophie S Y Chan, Lynette J Schedlich, Stephen M Twigg, Robert C Baxter. Inhibition of adipocyte differentiation by insulin-like growth factor-binding protein-3. American journal of physiology. Endocrinology and metabolism. 2009 Apr; 296(4):E654-63. doi: 10.1152/ajpendo.90846.2008. [PMID: 19141684]
  • Chae Hwa Kwon, Ji Yeon Park, Thae Hyun Kim, Jae Suk Woo, Yong Keun Kim. Ciglitazone induces apoptosis via activation of p38 MAPK and AIF nuclear translocation mediated by reactive oxygen species and Ca(2+) in opossum kidney cells. Toxicology. 2009 Mar; 257(1-2):1-9. doi: 10.1016/j.tox.2008.11.019. [PMID: 19110029]
  • Michiel E Stegenga, Sandrine Florquin, Alex F de Vos, Tom van der Poll. The thiazolidinedione ciglitazone reduces bacterial outgrowth and early inflammation during Streptococcus pneumoniae pneumonia in mice. Critical care medicine. 2009 Feb; 37(2):614-8. doi: 10.1097/ccm.0b013e31819599b6. [PMID: 19114898]
  • Ulf Panzer, Gunther Zahner, Ulrike Wienberg, Oliver M Steinmetz, Anett Peters, Jan-Eric Turner, Hans-Joachim Paust, Gunter Wolf, Rolf A K Stahl, André Schneider. 15-deoxy-Delta12,14-prostaglandin J2 inhibits INF-gamma-induced JAK/STAT1 signalling pathway activation and IP-10/CXCL10 expression in mesangial cells. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2008 Dec; 23(12):3776-85. doi: 10.1093/ndt/gfn361. [PMID: 18596134]
  • Utpal Sen, Walter E Rodriguez, Neetu Tyagi, Munish Kumar, Soumi Kundu, Suresh C Tyagi. Ciglitazone, a PPARgamma agonist, ameliorates diabetic nephropathy in part through homocysteine clearance. American journal of physiology. Endocrinology and metabolism. 2008 Nov; 295(5):E1205-12. doi: 10.1152/ajpendo.90534.2008. [PMID: 18780770]
  • Ranjit S Chima, Paul W Hake, Giovanna Piraino, Prajakta Mangeshkar, Alvin Denenberg, Basilia Zingarelli. Ciglitazone ameliorates lung inflammation by modulating the inhibitor kappaB protein kinase/nuclear factor-kappaB pathway after hemorrhagic shock. Critical care medicine. 2008 Oct; 36(10):2849-57. doi: 10.1097/ccm.0b013e318187810e. [PMID: 18828195]
  • Duygu Ozel Demiralp, Huseyin Aktas, Nejat Akar. The effect of plasminogen activator inhibitor-1 -675 4G/5G polymorphism on PAI-1 gene expression and adipocyte differentiation. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 2008 Oct; 14(4):438-46. doi: 10.1177/1076029607305081. [PMID: 18160587]
  • Walter E Rodriguez, Utpal Sen, Neetu Tyagi, Munish Kumar, Gene Carneal, Deep Aggrawal, Justin Newsome, Suresh C Tyagi. PPAR gamma agonist normalizes glomerular filtration rate, tissue levels of homocysteine, and attenuates endothelial-myocyte uncoupling in alloxan induced diabetic mice. International journal of biological sciences. 2008 Aug; 4(4):236-44. doi: 10.7150/ijbs.4.236. [PMID: 18690293]
  • Chae Hwa Kwon, Chang Soo Yoon, Yong Keun Kim. Ciglitazone induces caspase-independent apoptosis via p38-dependent AIF nuclear translocation in renal epithelial cells. Toxicology. 2008 Feb; 244(1):13-24. doi: 10.1016/j.tox.2007.10.019. [PMID: 18082925]
  • Yan J Jiang, Biao Lu, Peggy Kim, Gyorgy Paragh, Gerd Schmitz, Peter M Elias, Kenneth R Feingold. PPAR and LXR activators regulate ABCA12 expression in human keratinocytes. The Journal of investigative dermatology. 2008 Jan; 128(1):104-9. doi: 10.1038/sj.jid.5700944. [PMID: 17611579]
  • Jean-Yves Jouzeau, David Moulin, Meriem Koufany, Sylvie Sebillaud, Arnaud Bianchi, Patrick Netter. [Pathophysiological relevance of peroxisome proliferators activated receptors (PPAR) to joint diseases - the pro and con of agonists]. Journal de la Societe de biologie. 2008; 202(4):289-312. doi: 10.1051/jbio:2008034. [PMID: 19094928]
  • Woo Jae Kim, Joon Hyun Kim, Sung Key Jang. Anti-inflammatory lipid mediator 15d-PGJ2 inhibits translation through inactivation of eIF4A. The EMBO journal. 2007 Dec; 26(24):5020-32. doi: 10.1038/sj.emboj.7601920. [PMID: 18034160]
  • Sandra Brunelleschi, Claudio Bardelli, Angela Amoruso, Gabriele Gunella, Francesca Ieri, Annalisa Romani, Walter Malorni, Flavia Franconi. Minor polar compounds extra-virgin olive oil extract (MPC-OOE) inhibits NF-kappa B translocation in human monocyte/macrophages. Pharmacological research. 2007 Dec; 56(6):542-9. doi: 10.1016/j.phrs.2007.10.001. [PMID: 17997324]
  • Corinne Pellieux, Christophe Montessuit, Irène Papageorgiou, René Lerch. Inactivation of peroxisome proliferator-activated receptor isoforms alpha, beta/delta, and gamma mediate distinct facets of hypertrophic transformation of adult cardiac myocytes. Pflugers Archiv : European journal of physiology. 2007 Dec; 455(3):443-54. doi: 10.1007/s00424-007-0297-0. [PMID: 17643263]
  • Basilia Zingarelli, Paul W Hake, Prajakta Mangeshkar, Michael O'Connor, Timothy J Burroughs, Giovanna Piraino, Alvin Denenberg, Hector R Wong. Diverse cardioprotective signaling mechanisms of peroxisome proliferator-activated receptor-gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone, in reperfusion injury: role of nuclear factor-kappaB, heat shock factor 1, and Akt. Shock (Augusta, Ga.). 2007 Nov; 28(5):554-63. doi: 10.1097/shk.0b013e31804f56b9. [PMID: 17589386]
  • Cai-Yan Zhao, Jun-Ying Zhou, Liu Yang, Ya-Dong Wang. [Molecular mechanism of ciglitazone inhibiting the expression of extracellular matrix in human hepatic stellate cells]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. 2007 Nov; 15(11):840-4. doi: ". [PMID: 18073068]
  • Masaaki Niino. Peroxisome proliferator-activated receptor agonists as potential therapeutic agents in multiple sclerosis. Mini reviews in medicinal chemistry. 2007 Nov; 7(11):1129-35. doi: 10.2174/138955707782331687. [PMID: 18045216]
  • Sai Wang Seto, Tsz Yan Lam, George P H Leung, Alice L S Au, Sai Ming Ngai, Shun Wan Chan, Yiu Wa Kwan. Comparison of vascular relaxation, lipolysis and glucose uptake by peroxisome proliferator-activated receptor-gamma activation in +db/+m and +db/+db mice. European journal of pharmacology. 2007 Oct; 572(1):40-8. doi: 10.1016/j.ejphar.2007.05.070. [PMID: 17603034]
  • Tzu-Hung Lin, Rong-Sen Yang, Chih-Hsin Tang, Chih-Peng Lin, Wen-Mei Fu. PPARgamma inhibits osteogenesis via the down-regulation of the expression of COX-2 and iNOS in rats. Bone. 2007 Oct; 41(4):562-74. doi: 10.1016/j.bone.2007.06.017. [PMID: 17669705]
  • Patrizia Risé, Silvia Ghezzi, Romina Carissimi, Francesca Mastromauro, Anna Petroni, Claudio Galli. Delta5 desaturase mRNA levels are increased by simvastatin via SREBP-1 at early stages, not via PPARalpha, in THP-1 cells. European journal of pharmacology. 2007 Oct; 571(2-3):97-105. doi: 10.1016/j.ejphar.2007.06.021. [PMID: 17655842]
  • Héctor Giral, Ricardo Villa-Bellosta, Julia Catalán, Víctor Sorribas. Cytotoxicity of peroxisome proliferator-activated receptor alpha and gamma agonists in renal proximal tubular cell lines. Toxicology in vitro : an international journal published in association with BIBRA. 2007 Sep; 21(6):1066-76. doi: 10.1016/j.tiv.2007.03.021. [PMID: 17521863]
  • Zivar Yousefipour, Hantz Hercule, Luan Truong, Adebayo Oyekan, Mohammad Newaz. Ciglitazone, a peroxisome proliferator-activated receptor gamma inducer, ameliorates renal preglomerular production and activity of angiotensin II and thromboxane A2 in glycerol-induced acute renal failure. The Journal of pharmacology and experimental therapeutics. 2007 Aug; 322(2):461-8. doi: 10.1124/jpet.107.122473. [PMID: 17494862]
  • Roberto Scatena, Patrizia Bottoni, Giuseppe E Martorana, Federica Vincenzoni, Giorgia Botta, Paola Pastore, Bruno Giardina. Mitochondria, ciglitazone and liver: a neglected interaction in biochemical pharmacology. European journal of pharmacology. 2007 Jul; 567(1-2):50-8. doi: 10.1016/j.ejphar.2007.04.017. [PMID: 17499714]
  • Cynthia Lee Richard, Jonathan Blay. Thiazolidinedione drugs down-regulate CXCR4 expression on human colorectal cancer cells in a peroxisome proliferator activated receptor gamma-dependent manner. International journal of oncology. 2007 May; 30(5):1215-22. doi: . [PMID: 17390024]
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  • Takehiko Maeda, Norikazu Kiguchi, Yohji Fukazawa, Akihiro Yamamoto, Masanobu Ozaki, Shiroh Kishioka. Peroxisome proliferator-activated receptor gamma activation relieves expression of behavioral sensitization to methamphetamine in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2007 May; 32(5):1133-40. doi: 10.1038/sj.npp.1301213. [PMID: 17019405]
  • S Mandard, R Stienstra, P Escher, N S Tan, I Kim, F J Gonzalez, W Wahli, B Desvergne, M Müller, S Kersten. Glycogen synthase 2 is a novel target gene of peroxisome proliferator-activated receptors. Cellular and molecular life sciences : CMLS. 2007 May; 64(9):1145-57. doi: 10.1007/s00018-007-7006-1. [PMID: 17437057]
  • Sakiko Ohga, Kenichi Shikata, Kosuke Yozai, Shinichi Okada, Daisuke Ogawa, Hitomi Usui, Jun Wada, Yasushi Shikata, Hirofumi Makino. Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation. American journal of physiology. Renal physiology. 2007 Apr; 292(4):F1141-50. doi: 10.1152/ajprenal.00288.2005. [PMID: 17190910]
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  • Biao Lu, Arthur H Moser, Judy K Shigenaga, Kenneth R Feingold, Carl Grunfeld. Type II nuclear hormone receptors, coactivator, and target gene repression in adipose tissue in the acute-phase response. Journal of lipid research. 2006 Oct; 47(10):2179-90. doi: 10.1194/jlr.m500540-jlr200. [PMID: 16847310]
  • Sara Vignati, Veronica Albertini, Andrea Rinaldi, Ivo Kwee, Cristina Riva, Rita Oldrini, Carlo Capella, Francesco Bertoni, Giuseppina M Carbone, Carlo V Catapano. Cellular and molecular consequences of peroxisome proliferator-activated receptor-gamma activation in ovarian cancer cells. Neoplasia (New York, N.Y.). 2006 Oct; 8(10):851-61. doi: 10.1593/neo.06433. [PMID: 17032502]
  • Mohammad Newaz, Zivar Yousefipour, Adebayo Oyekan. Role of PPAR-gamma on the pathogenesis and vascular changes in glycerol-induced acute renal failure. Pharmacological research. 2006 Sep; 54(3):234-40. doi: 10.1016/j.phrs.2006.03.023. [PMID: 16820301]
  • Sik Lee, Won Kim, Sang-Ok Moon, Mi Jeong Sung, Duk Hoon Kim, Kyung Pyo Kang, Yong Bum Jang, Jung Eun Lee, Kyu Yun Jang, Sung Kwang Park. Rosiglitazone ameliorates cisplatin-induced renal injury in mice. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2006 Aug; 21(8):2096-105. doi: 10.1093/ndt/gfl194. [PMID: 16728429]
  • S P Poulos, G J Hausman. A comparison of thiazolidinedione-induced adipogenesis and myogenesis in stromal-vascular cells from subcutaneous adipose tissue or semitendinosus muscle of postnatal pigs. Journal of animal science. 2006 May; 84(5):1076-82. doi: 10.2527/2006.8451076x. [PMID: 16612009]
  • Wei-ming Wang, Feng Liu, Nan Chen. [Effects of peroxisome proliferators-activated receptor gamma agonists on transforming growth factor-beta1 and Smads signal pathway: experiment with rat renal fibroblasts]. Zhonghua yi xue za zhi. 2006 Mar; 86(11):740-4. doi: NULL. [PMID: 16681946]
  • Ravinder S Chana, Nigel J Brunskill. Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma. American journal of nephrology. 2006; 26(1):67-74. doi: 10.1159/000091807. [PMID: 16508249]
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