TRIPARANOL (BioDeep_00000388899)
代谢物信息卡片
TRIPARANOL
化学式: C27H32ClNO2 (437.2121442)
中文名称: 曲帕拉醇
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN(CC)CCOC1=CC=C(C=C1)C(CC2=CC=C(C=C2)Cl)(C3=CC=C(C=C3)C)O
InChI: InChI=1S/C27H32ClNO2/c1-4-29(5-2)18-19-31-26-16-12-24(13-17-26)27(30,23-10-6-21(3)7-11-23)20-22-8-14-25(28)15-9-22/h6-17,30H,4-5,18-20H2,1-3H3
描述信息
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent
D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents
D009676 - Noxae > D000963 - Antimetabolites
同义名列表
1 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:135714
- PubChem: 6536
- Metlin: METLIN6203
- ChEMBL: CHEMBL187709
- MeSH: Triparanol
- CAS: 78-41-1
- PMhub: MS000238926
- RefMet: Triparanol
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Cell reports.
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Molecular pharmacology.
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1965 Nov; 5(6):580-91. doi:
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1965 Sep; 116(?):366-72. doi:
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1965 Apr; 118(?):1140-5. doi:
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The British journal of dermatology.
1965 Mar; 77(?):115-29. doi:
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1965 Feb; 260(?):2289-92. doi:
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1965 Jan; 6(?):37-42. doi:
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1964 Dec; 84(?):739-48. doi:
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Acta medica Scandinavica.
1964 Dec; 176(?):657-63. doi:
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Acta medicinae Okayama.
1963; 17(?):273-8. doi:
NULL. [PMID: 14168971] - H ENGELBERG. Effects of triparanol on serum low-density lipoproteins and cholesterol.
Geriatrics.
1962 Aug; 17(?):528-31. doi:
NULL. [PMID: 13890232] - A KONTTINEN. The effect of triparanol on the serum lipid pattern in hypercholesteremic patients.
Acta medica Scandinavica.
1962 Jun; 171(?):753-7. doi:
10.1111/j.0954-6820.1962.tb04241.x. [PMID: 14458285] - G MARCHESE. [Action of triparanol on blood lipid changes].
Giornale di gerontologia.
1962 May; 10(?):449-61. doi:
". [PMID: 14469633] - K CRAMER. Serum beta-lipoprotein lipids and protein during administration of Triparanol.
Acta medica Scandinavica.
1962 Apr; 171(?):435-9. doi:
NULL. [PMID: 13882000] - E M GOYETTE, A SAAD. The use of triparanol and sodium dextrothyroxine to lower serum cholesterol.
Angiology.
1962 Feb; 13(?):88-93. doi:
NULL. [PMID: 13900898] - D Berkowitz, M W Croll, W Likoff. The effects of sitosterol, nicotinic acid and triparanol on fat tolerance.
The American journal of clinical nutrition.
1962 02; 10(?):107-10. doi:
10.1093/ajcn/10.2.107. [PMID: 13867897] - M HODARA. [The hypocholesterolemic action of triparanol].
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris.
1962 Jan; 38(?):267-8. doi:
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Journal of atherosclerosis research.
1962 Jan; 2(?):96-103. doi:
10.1016/s0368-1319(62)80057-x. [PMID: 14007156] - B A Sachs, L Wolfman. Studies of serum desmosterol levels in hypercholesteremic subjects treated with triparanol (MER-29).
The American journal of clinical nutrition.
1961 Nov; 9(?):760-3. doi:
10.1093/ajcn/9.6.760. [PMID: 14495832] - W A OILLE. Serum cholesterol with triparanol (Mer/29) administration.
Applied therapeutics.
1961 Apr; 3(?):251-5. doi:
NULL. [PMID: 13939711] - J AVIGAN, D STEINBERG, H E VROMAN, M J THOMPSON, E MOSETTIG. Studies of cholesterol biosynthesis. I. The identification of desmosterol in serum and tissues of animals and man treated with MER-29.
The Journal of biological chemistry.
1960 Nov; 235(?):3123-6. doi:
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American heart journal.
1960 Oct; 60(?):536-8. doi:
10.1016/0002-8703(60)90431-2. [PMID: 13707585] - P E WAIBEL, R E BURGER, R A BALL, J H SAUTTER, I E LIENER, B S POMEROY. Effect of triparanol on beta-aminopropionitrile-induced dissecting aneurysm and blood lipid levels in the turkey.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1960 Aug; 104(?):673-6. doi:
10.3181/00379727-104-25948. [PMID: 13782555] - A RUSKIN, B RUSKIN. Effect of MER-29 (triparanol) on serum cholesterol, cholesterol esters and liver enzymes.
Progress in cardiovascular diseases.
1960 May; 2(?):624-30. doi:
10.1016/s0033-0620(60)80045-x. [PMID: 14440267] - D STEINBERG, J AVIGAN, E B FEIGELSON. Identification of 24-dehydrocholesterol in the serum of patients treated with MER-29.
Progress in cardiovascular diseases.
1960 May; 2(?):586-92. doi:
10.1016/s0033-0620(60)80038-2. [PMID: 13834161] - R V FORD. The effect of MER-29, a cholesterol synthesis inhibitor, on adrenal function, blood clotting mechanisms, and serum lipids, before and after simulated stress in man.
Progress in cardiovascular diseases.
1960 May; 2(?):548-52. doi:
10.1016/s0033-0620(60)80030-8. [PMID: 13823923] - R H ROSENMAN, M FRIEDMAN. Observations on the effect of triparanol (MER-29) on the serum cholesterol of selected human subjects.
Progress in cardiovascular diseases.
1960 May; 2(?):605-11. doi:
10.1016/s0033-0620(60)80041-2. [PMID: 14439028] - M E TODD. Effect of MER-29 on serum cholesterol and blood clotting mechanisms: a plan of study and preliminary findings. II.
Progress in cardiovascular diseases.
1960 May; 2(?):555-62. doi:
10.1016/s0033-0620(60)80032-1. [PMID: 13838620] - T R BLOHM, T KARIYA, M W LAUGHLIN. Effects of MER-29, a cholesterol synthesis inhibitor, on mammalian tissue lipides.
Archives of biochemistry and biophysics.
1959 Nov; 85(?):250-63. doi:
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