N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenamide (BioDeep_00000388888)
代谢物信息卡片
N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenamide
化学式: C26H33NO2 (391.25111580000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(=O)Nc1ccc(O)cc1
InChI:
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
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Plant Reactome(0)
INOH(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
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Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Benjamin T Bikman, Yuguang Guan, Guanghou Shui, M Mobin Siddique, William L Holland, Ji Yun Kim, Gemma Fabriàs, Markus R Wenk, Scott A Summers. Fenretinide prevents lipid-induced insulin resistance by blocking ceramide biosynthesis.
The Journal of biological chemistry.
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Biochemistry and cell biology = Biochimie et biologie cellulaire.
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British journal of cancer.
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Biological & pharmaceutical bulletin.
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Neuroscience letters.
2011 Sep; 502(1):24-9. doi:
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Molecular pharmacology.
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Anticancer research.
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British journal of pharmacology.
2011 Feb; 162(4):989-99. doi:
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Journal of lipids.
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Journal of lipids.
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The Journal of biological chemistry.
2010 Dec; 285(49):38568-79. doi:
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Cancer chemotherapy and pharmacology.
2010 Oct; 66(5):993-8. doi:
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Journal of lipid research.
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Free radical biology & medicine.
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The Journal of neuroscience : the official journal of the Society for Neuroscience.
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British journal of cancer.
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Investigational new drugs.
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Molecular cancer therapeutics.
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American journal of physiology. Endocrinology and metabolism.
2009 Dec; 297(6):E1420-9. doi:
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Cancer letters.
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PLoS pathogens.
2009 Oct; 5(10):e1000623. doi:
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Neuroscience.
2009 Sep; 163(1):286-95. doi:
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Analytical biochemistry.
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Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
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American journal of respiratory cell and molecular biology.
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Analytical biochemistry.
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Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
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Diabetes.
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Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.
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Investigative ophthalmology & visual science.
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American journal of respiratory cell and molecular biology.
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Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2007 Jul; 25(19):2685-90. doi:
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Investigational new drugs.
2007 Jun; 25(3):197-203. doi:
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Clinical cancer research : an official journal of the American Association for Cancer Research.
2007 May; 13(10):3079-86. doi:
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PLoS medicine.
2007 Mar; 4(3):e103. doi:
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Neoplasia (New York, N.Y.).
2007 Mar; 9(3):246-53. doi:
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British journal of cancer.
2007 Feb; 96(3):424-31. doi:
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Carcinogenesis.
2007 Feb; 28(2):378-89. doi:
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Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.
2007; 174(?):91-100. doi:
10.1007/978-3-540-37696-5_9. [PMID: 17302189] - Sherimay Ablan, Satinder S Rawat, Mathias Viard, Ji Ming Wang, Anu Puri, Robert Blumenthal. The role of cholesterol and sphingolipids in chemokine receptor function and HIV-1 envelope glycoprotein-mediated fusion.
Virology journal.
2006 Dec; 3(?):104. doi:
10.1186/1743-422x-3-104. [PMID: 17187670] - Ann B Goodman. Retinoid receptors, transporters, and metabolizers as therapeutic targets in late onset Alzheimer disease.
Journal of cellular physiology.
2006 Dec; 209(3):598-603. doi:
10.1002/jcp.20784. [PMID: 17001693] - Morris Pollard, Mark A Suckow. Dietary prevention of hormone refractory prostate cancer in Lobund-Wistar rats: a review of studies in a relevant animal model.
Comparative medicine.
2006 Dec; 56(6):461-7. doi:
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Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2006 Oct; 15(10):1914-9. doi:
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Bioorganic & medicinal chemistry.
2006 Sep; 14(17):6089-96. doi:
10.1016/j.bmc.2006.05.013. [PMID: 16725328] - Judith G Villablanca, Mark D Krailo, Matthew M Ames, Joel M Reid, Gregory H Reaman, C Patrick Reynolds, Patrick C Reynolds. Phase I trial of oral fenretinide in children with high-risk solid tumors: a report from the Children's Oncology Group (CCG 09709).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2006 Jul; 24(21):3423-30. doi:
10.1200/jco.2005.03.9271. [PMID: 16849757] - Masami Suganuma, Miki Kurusu, Kaori Suzuki, Emi Tasaki, Hirota Fujiki. Green tea polyphenol stimulates cancer preventive effects of celecoxib in human lung cancer cells by upregulation of GADD153 gene.
International journal of cancer.
2006 Jul; 119(1):33-40. doi:
10.1002/ijc.21809. [PMID: 16463383] - Weihong Yin, Satish Cheepala, Jennifer N Roberts, Keith Syson-Chan, John DiGiovanni, John L Clifford. Active Stat3 is required for survival of human squamous cell carcinoma cells in serum-free conditions.
Molecular cancer.
2006 Apr; 5(?):15. doi:
10.1186/1476-4598-5-15. [PMID: 16603078] - Morando Soffritti, Fiorella Belpoggi, Davide Degli Esposti, Luca Lambertini, Eva Tibaldi, Anna Rigano. First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats.
Environmental health perspectives.
2006 Mar; 114(3):379-85. doi:
10.1289/ehp.8711. [PMID: 16507461] - Catherine M Finnegan, Robert Blumenthal. Fenretinide inhibits HIV infection by promoting viral endocytosis.
Antiviral research.
2006 Feb; 69(2):116-23. doi:
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Bioorganic & medicinal chemistry.
2006 Jan; 14(2):409-17. doi:
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Investigative ophthalmology & visual science.
2005 Dec; 46(12):4393-401. doi:
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Investigational new drugs.
2005 Oct; 23(5):417-28. doi:
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Nutrition journal.
2005 Sep; 4(?):25. doi:
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Nature.
2005 Jul; 436(7049):356-62. doi:
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Investigational new drugs.
2005 Mar; 23(2):179-85. doi:
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Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2004 Nov; 22(21):4282-9. doi:
10.1200/jco.2004.09.096. [PMID: 15514370] - Maria Grazia Villani, Valentina Appierto, Elena Cavadini, Manuela Valsecchi, Sandro Sonnino, Robert W Curley, Franca Formelli. Identification of the fenretinide metabolite 4-oxo-fenretinide present in human plasma and formed in human ovarian carcinoma cells through induction of cytochrome P450 26A1.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2004 Sep; 10(18 Pt 1):6265-75. doi:
10.1158/1078-0432.ccr-04-0655. [PMID: 15448016] - Penny E Lovat, Federica Di Sano, Marco Corazzari, Barbara Fazi, Raffaele Perrone Donnorso, Andy D J Pearson, Andrew G Hall, Christopher P F Redfern, Mauro Piacentini. Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide.
Journal of the National Cancer Institute.
2004 Sep; 96(17):1288-99. doi:
10.1093/jnci/djh254. [PMID: 15339967] - Hye-Sook Han, Youn-Ja Kwon, Si-Ho Park, Eun-Joo Kim, Young-Soy Rho, Hong-Sig Sin, Soo-Jong Um. Potent effect of 5-HPBR, a butanoate derivative of 4-HPR, on cell growth and apoptosis in cancer cells.
International journal of cancer.
2004 Mar; 109(1):58-64. doi:
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Archives of biochemistry and biophysics.
2003 Nov; 419(2):234-43. doi:
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The Journal of dairy research.
2003 Nov; 70(4):367-72. doi:
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Clinical cancer research : an official journal of the American Association for Cancer Research.
2003 Oct; 9(13):4722-9. doi:
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Biological & pharmaceutical bulletin.
2003 Oct; 26(10):1412-7. doi:
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Clinical cancer research : an official journal of the American Association for Cancer Research.
2003 Jul; 9(7):2400-5. doi:
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Clinical cancer research : an official journal of the American Association for Cancer Research.
2003 Jun; 9(6):2032-9. doi:
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Journal of the National Cancer Institute.
2003 Feb; 95(4):291-302. doi:
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Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2003 Jan; 12(1):34-41. doi:
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The Journal of biological chemistry.
2002 Dec; 277(51):49531-7. doi:
10.1074/jbc.m209962200. [PMID: 12388538] - Noriko Takahashi, Toshihiro Ohba, Shin-ichi Togashi, Tetsuya Fukui. Biological activity of p-methylaminophenol, an essential structural component of N-(4-hydroxyphenyl)retinamide, fenretinide.
Journal of biochemistry.
2002 Nov; 132(5):767-74. doi:
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Molecular cancer therapeutics.
2002 Jul; 1(9):719-26. doi:
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British journal of cancer.
2002 Jun; 86(12):1951-6. doi:
10.1038/sj.bjc.6600356. [PMID: 12085192] - Amanda H Prowse, Lisa Vanderveer, Simon W F Milling, Zhong-Zong Pan, Roland L Dunbrack, Xiang-Xi Xu, Andrew K Godwin. OVCA2 is downregulated and degraded during retinoid-induced apoptosis.
International journal of cancer.
2002 May; 99(2):185-92. doi:
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Nutrition and cancer.
2002; 43(1):67-75. doi:
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