6,6-Bieckol (BioDeep_00000377287)
Marine Natural Products
代谢物信息卡片
化学式: C36H22O18 (742.0806112)
中文名称: 6,6’-双鹅掌菜酚
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=C(C=C(C=C1O)OC2=C(C=C(C3=C2OC4=C(C=C(C(=C4O3)C5=C6C(=C(C=C5O)O)OC7=C(O6)C(=CC(=C7OC8=CC(=CC(=C8)O)O)O)O)O)O)O)O)O
InChI: InChI=1S/C36H22O18/c37-11-1-12(38)4-15(3-11)49-29-21(45)9-23(47)31-35(29)53-27-19(43)7-17(41)25(33(27)51-31)26-18(42)8-20(44)28-34(26)52-32-24(48)10-22(46)30(36(32)54-28)50-16-5-13(39)2-14(40)6-16/h1-10,37-48H
描述信息
A phlorotanin that is 1,1-bioxanthrene substituted by 3,5-dihydroxyphenoxy groups at position 6 and 6 and hydroxy groups at positions 2, 2, 4, 4, 7, 7, 9 and 9 respectively. It is isolated from an edible marine brown alga Ecklonia cava and exhibits antioxidant activity.
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:65496
- PubChem: 137388
- ChEMBL: CHEMBL502202
- CAS: 88095-81-2
- PMhub: MS000214706
- MetaboLights: MTBLC65496
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Myeongjoo Son, Seyeon Oh, Hye Sun Lee, Dong-Min Chung, Ji Tae Jang, You-Jin Jeon, Chang Hu Choi, Kook Yang Park, Kuk Hui Son, Kyunghee Byun. Ecklonia Cava Extract Attenuates Endothelial Cell Dysfunction by Modulation of Inflammation and Brown Adipocyte Function in Perivascular Fat Tissue.
Nutrients.
2019 Nov; 11(11):. doi:
10.3390/nu11112795
. [PMID: 31731817] - Junwon Choi, Seyeon Oh, Myeongjoo Son, Kyunghee Byun. Pyrogallol-Phloroglucinol-6,6-Bieckol Alleviates Obesity and Systemic Inflammation in a Mouse Model by Reducing Expression of RAGE and RAGE Ligands.
Marine drugs.
2019 Oct; 17(11):. doi:
10.3390/md17110612
. [PMID: 31661887] - Myeongjoo Son, Seyeon Oh, Chang Hu Choi, Kook Yang Park, Kuk Hui Son, Kyunghee Byun. Pyrogallol-Phloroglucinol-6,6-Bieckol from Ecklonia cava Attenuates Tubular Epithelial Cell (TCMK-1) Death in Hypoxia/Reoxygenation Injury.
Marine drugs.
2019 Oct; 17(11):. doi:
10.3390/md17110602
. [PMID: 31652920] - Myeongjoo Son, Seyeon Oh, Hye Sun Lee, BoMi Ryu, Yunfei Jiang, Ji Tae Jang, You-Jin Jeon, Kyunghee Byun. Pyrogallol-Phloroglucinol-6,6'-Bieckol from Ecklonia cava Improved Blood Circulation in Diet-Induced Obese and Diet-Induced Hypertension Mouse Models.
Marine drugs.
2019 May; 17(5):. doi:
10.3390/md17050272
. [PMID: 31071969] - Seyeon Oh, Myeongjoo Son, Hye Sun Lee, Hyun-Soo Kim, You-Jin Jeon, Kyunghee Byun. Protective Effect of Pyrogallol-Phloroglucinol-6,6-Bieckol from Ecklonia cava on Monocyte-Associated Vascular Dysfunction.
Marine drugs.
2018 Nov; 16(11):. doi:
10.3390/md16110441
. [PMID: 30423960] - Mi-Hwa Park, Soo-Jin Heo, Kil-Nam Kim, Ginnae Ahn, Pyo-Jam Park, Sang-Ho Moon, Byong-Tae Jeon, Seung-Hong Lee. 6,6'-Bieckol protects insulinoma cells against high glucose-induced glucotoxicity by reducing oxidative stress and apoptosis.
Fitoterapia.
2015 Oct; 106(?):135-40. doi:
10.1016/j.fitote.2015.08.014
. [PMID: 26343533] - Tae-Hyung Kwon, Yong-Xiang Wu, Jong-Shik Kim, Jung-Hee Woo, Kyu Tae Park, O Jun Kwon, Hyun-Ju Seo, Taewan Kim, Nyun-Ho Park. 6,6'-Bieckol inhibits adipocyte differentiation through downregulation of adipogenesis and lipogenesis in 3T3-L1 cells.
Journal of the science of food and agriculture.
2015 Jul; 95(9):1830-7. doi:
10.1002/jsfa.6881
. [PMID: 25142414] - Eun-Ji Joung, Min-Sup Lee, Ji-Woong Choi, Jong-Soon Kim, Taisun Shin, Bok-Mi Jung, Na Young Yoon, Chi-Won Lim, Jae-Il Kim, Hyeung-Rak Kim. Anti-inflammatory effect of ethanolic extract from Myagropsis myagroides on murine macrophages and mouse ear edema.
BMC complementary and alternative medicine.
2012 Oct; 12(?):171. doi:
10.1186/1472-6882-12-171
. [PMID: 23031211]