drimane (BioDeep_00000376088)
代谢物信息卡片
drimane
化学式: C15H28 (208.2190888)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CCC2C(C)(C)CCCC2(C)C1C
InChI: InChI=1S/C15H28/c1-11-7-8-13-14(3,4)9-6-10-15(13,5)12(11)2/h11-13H,6-10H2,1-5H3/t11-,12-,13-,15+/m0/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jing-Wen Wang, Dong-Yun Liu, Hou-Ze Zhang, Zhen Tan, Cai-Juan Zheng, Guang-Ying Chen, Xu-Hua Nong. Drimane-type sesquiterpenoids and their anti-inflammatory evaluation from Pyrrhoderma noxium HNNU0524.
Natural product research.
2024 May; 38(10):1711-1718. doi:
10.1080/14786419.2023.2218008. [PMID: 37259794] - Meng Zhang, Huan Zhao, Jing-Wen Kong, Mei-Gu Chen, Qing Yang, Wei Xu, Dan Hu, Liang-Dong Guo, Guo-Dong Chen, Hao Gao. New sesquiterpenoids from Biscogniauxia sp.
Journal of Asian natural products research.
2024 Feb; 26(2):214-227. doi:
10.1080/10286020.2024.2314188. [PMID: 38353486] - Shengxin Sun, Xia Wang, René Csuk, Shengkun Li. Practical Synthesis and Antifungal Investigation of Drimane Meroterpenoids Enabled by Nickel-Catalyzed Decarboxylative Coupling.
Journal of natural products.
2023 06; 86(6):1420-1427. doi:
10.1021/acs.jnatprod.3c00100. [PMID: 37226456] - Hong-Liang Wang, Ran Li, Min Zhao, Zeng-Yiyi Wang, Hua Tang, Zheng-Yu Cao, Gui-Liang Zheng, Wen Zhang. A Drimane Meroterpenoid Borate as a Synchronous Ca+ Oscillation Inhibitor from the Coral-Associated Fungus Alternaria sp. ZH-15.
Journal of natural products.
2023 Feb; 86(2):429-433. doi:
10.1021/acs.jnatprod.2c01028. [PMID: 36729068] - Xiaoshuang Gou, Danmei Tian, Jihua Wei, Yihan Ma, Yixue Zhang, Mei Chen, Wenjuan Ding, Bin Wu, Jinshan Tang. New Drimane Sesquiterpenes and Polyketides from Marine-Derived Fungus Penicillium sp. TW58-16 and Their Anti-Inflammatory and α-Glucosidase Inhibitory Effects.
Marine drugs.
2021 Jul; 19(8):. doi:
10.3390/md19080416. [PMID: 34436259] - Cristian Paz, Sharon Viscardi, Andres Iturra, Victor Marin, Felipe Miranda, Patricio Javier Barra, Isabel Mendez, Paola Duran. Antifungal Effects of Drimane Sesquiterpenoids Isolated from Drimys winteri against Gaeumannomyces graminis var. tritici.
Applied and environmental microbiology.
2020 11; 86(24):. doi:
10.1128/aem.01834-20. [PMID: 33036992] - Sahla Belhadj, Henda Keskes, Cécile Apel, Fanny Roussi, Marc Litaudon, Olfa Hentati, Noureddine Allouche. Anti-diabetic and lipid-lowering effects of drimane sesquiterpenoids isolated from Zygogynum pancheri.
Chemico-biological interactions.
2020 Oct; 330(?):109167. doi:
10.1016/j.cbi.2020.109167. [PMID: 32603660] - Hong-Liang Wang, Ran Li, Jiao Li, Jing He, Zheng-Yu Cao, Tibor Kurtán, Attila Mándi, Gui-Liang Zheng, Wen Zhang. Alternarin A, a Drimane Meroterpenoid, Suppresses Neuronal Excitability from the Coral-Associated Fungi Alternaria sp. ZH-15.
Organic letters.
2020 04; 22(8):2995-2998. doi:
10.1021/acs.orglett.0c00746. [PMID: 32237750] - Li-Hua Zhang, Gang Chen, Yi Sun, Hai-Feng Wang, Jiao Bai, Hui-Ming Hua, Yue-Hu Pei. Seven new Drimane-Type Sesquiterpenoids from a Marine-Derived Fungus Paraconiothyrium sporulosum YK-03.
Molecules (Basel, Switzerland).
2019 May; 24(9):. doi:
10.3390/molecules24091817. [PMID: 31083454] - Zoxolo N Nyaba, Pretty Murambiwa, Andy R Opoku, Samson Mukaratirwa, Francis O Shode, Mthokozisi B C Simelane. Isolation, characterization, and biological evaluation of a potent anti-malarial drimane sesquiterpene from Warburgia salutaris stem bark.
Malaria journal.
2018 Aug; 17(1):296. doi:
10.1186/s12936-018-2439-6. [PMID: 30111328] - Eduarda Fratoni, Amanda Ellen de Athayde, Marina da Silva Machado, Tailyn Zermiani, Ivonilce Venturi, Matheus Corrêa Dos Santos, Fabiane Lobato, Valdir Cechinel Filho, Gilberto Carlos Franchi, Alexandre Eduardo Nowill, José Roberto Santin, Angela Malheiros. Antiproliferative and toxicological properties of drimanes obtained from Drimys brasiliensis stem barks.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Jul; 103(?):1498-1506. doi:
10.1016/j.biopha.2018.04.103. [PMID: 29864935] - Miaofeng Ma, Jili Feng, Dezhi Wang, Shu-Wei Chen, Hui Xu. Synthesis and Antifungal Activities of Drimane-Amide Derivatives from Sclareol.
Combinatorial chemistry & high throughput screening.
2018; 21(7):501-509. doi:
10.2174/1386207321666180925164358. [PMID: 30255746] - Dangdang Li, Shasha Zhang, Zehua Song, Wei Li, Feng Zhu, Jiwen Zhang, Shengkun Li. Synthesis and bio-inspired optimization of drimenal: Discovery of chiral drimane fused oxazinones as promising antifungal and antibacterial candidates.
European journal of medicinal chemistry.
2018 Jan; 143(?):558-567. doi:
10.1016/j.ejmech.2017.11.051. [PMID: 29207338] - Shasha Zhang, Dangdang Li, Zehua Song, Chuanli Zang, Lu Zhang, Xiushi Song, Shengkun Li. 'Carbon Assimilation' Inspired Design and Divergent Synthesis of Drimane Meroterpenoid Mimics as Novel Fungicidal Leads.
Journal of agricultural and food chemistry.
2017 Oct; 65(41):9013-9021. doi:
10.1021/acs.jafc.7b03126. [PMID: 28949528] - Yang Hu, Lijun Tao, Hui Tan, Mian Zhang, Kuniyoshi Shimizu, Fei Zhang, Chaofeng Zhang. An Active Drimane-Type Lactone from Polygonum jucundum Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Mice Through TLR4-MAPKs Signaling Pathway.
Inflammation.
2017 Aug; 40(4):1204-1213. doi:
10.1007/s10753-017-0563-z. [PMID: 28455603] - Klaus Mathie, Johanna Lainer, Stefan Spreng, Corinna Dawid, David A Andersson, Stuart Bevan, Thomas Hofmann. Structure-Pungency Relationships and TRP Channel Activation of Drimane Sesquiterpenes in Tasmanian Pepper (Tasmannia lanceolata).
Journal of agricultural and food chemistry.
2017 Jul; 65(28):5700-5712. doi:
10.1021/acs.jafc.7b02356. [PMID: 28657737] - Jun-Chi Wang, Guang-Zhi Li, Na Lv, Lian-Gang Shen, Lei-Ling Shi, Jian-Yong Si. Cryptoporic acid S, a new drimane-type sesquiterpene ether of isocitric acid from the fruiting bodies of Cryptoporus volvatus.
Journal of Asian natural products research.
2017 Jul; 19(7):719-724. doi:
10.1080/10286020.2016.1240170. [PMID: 27756154] - Maurice G L Henquet, Neli Prota, Justin J J van der Hooft, Marina Varbanova-Herde, Raymond J M Hulzink, Martin de Vos, Marcel Prins, Michiel T J de Both, Maurice C R Franssen, Harro Bouwmeester, Maarten Jongsma. Identification of a drimenol synthase and drimenol oxidase from Persicaria hydropiper, involved in the biosynthesis of insect deterrent drimanes.
The Plant journal : for cell and molecular biology.
2017 Jun; 90(6):1052-1063. doi:
10.1111/tpj.13527. [PMID: 28258968] - Dahai He, Carla Slebodnick, L Harinantenaina Rakotondraibe. Bioactive drimane sesquiterpenoids and aromatic glycosides from Cinnamosma fragrans.
Bioorganic & medicinal chemistry letters.
2017 04; 27(8):1754-1759. doi:
10.1016/j.bmcl.2017.02.067. [PMID: 28274626] - Eduarda Fratoni, Vanessa Duarte Claudino, Rosendo Augusto Yunes, Gilberto C Franchi, Alexandre E Nowill, Valdir Cechinel Filho, Franco Delle Monache, Angela Malheiros. Further drimane sesquiterpenes from Drimys brasiliensis stem barks with cytotoxic potential.
Naunyn-Schmiedeberg's archives of pharmacology.
2016 Jul; 389(7):791-7. doi:
10.1007/s00210-016-1241-7. [PMID: 27095358] - Jiang-Bo He, Jian Tao, Xi-Song Miao, Wei Bu, Shen Zhang, Ze-Jun Dong, Zheng-Hui Li, Tao Feng, Ji-Kai Liu. Seven new drimane-type sesquiterpenoids from cultures of fungus Laetiporus sulphureus.
Fitoterapia.
2015 Apr; 102(?):1-6. doi:
10.1016/j.fitote.2015.01.022. [PMID: 25665943] - Wei Feng, Jun-Shan Yang. A new drimane sesquiterpenoid and a new triterpene lactone from fungus of Fomes officinalis.
Journal of Asian natural products research.
2015; 17(11):1065-72. doi:
10.1080/10286020.2015.1054378. [PMID: 26123159] - Yuya Nomoto, Liva Harinantenaina, Sachiko Sugimoto, Katsuyoshi Matsunami, Hideaki Otsuka. 3,4-seco-24-homo-28-nor-Cycloartane and drimane-type sesquiterpenes and their lactams from the EtOAc-soluble fraction of a leaf extract of Cinnamosma fragrans and their biological activity.
Journal of natural medicines.
2014 Jul; 68(3):513-20. doi:
10.1007/s11418-014-0828-x. [PMID: 24633883] - He-Ping Chen, Wen-Bin Dong, Tao Feng, Xia Yin, Zheng-Hui Li, Ze-Jun Dong, Yan Li, Ji-Kai Liu. Four new sesquiterpenoids from fruiting bodies of the fungus Inonotus rickii.
Journal of Asian natural products research.
2014; 16(6):581-6. doi:
10.1080/10286020.2014.925451. [PMID: 24974836] - Patrick Louis Cahill, David Burritt, Kevin Heasman, Andrew Jeffs, Jeanne Kuhajek. Screening for antioxidant and detoxification responses in Perna canaliculus Gmelin exposed to an antifouling bioactive intended for use in aquaculture.
Chemosphere.
2013 Oct; 93(6):931-8. doi:
10.1016/j.chemosphere.2013.05.058. [PMID: 23830117] - Ivan Montenegro, Luis Pino, Enrique Werner, Alejandro Madrid, Luis Espinoza, Luis Moreno, Joan Villena, Mauricio Cuellar. Comparative study on the larvicidal activity of drimane sesquiterpenes and nordrimane compounds against Drosophila melanogaster til-til.
Molecules (Basel, Switzerland).
2013 Apr; 18(4):4192-208. doi:
10.3390/molecules18044192. [PMID: 23612472] - Vanessa Duarte Claudino, Kesia Caroline da Silva, Valdir Cechinel Filho, Rosendo Augusto Yunes, Franco Delle Monache, Alberto Giménez, Efrain Salamanca, David Gutierrez-Yapu, Angela Malheiros. Drimanes from Drimys brasiliensis with leishmanicidal and antimalarial activity.
Memorias do Instituto Oswaldo Cruz.
2013 Apr; 108(2):140-4. doi:
10.1590/0074-0276108022013002. [PMID: 23579790] - Johannes C Liermann, Eckhard Thines, Till Opatz, Heidrun Anke. Drimane sesquiterpenoids from Marasmius sp. inhibiting the conidial germination of plant-pathogenic fungi.
Journal of natural products.
2012 Nov; 75(11):1983-6. doi:
10.1021/np300337w. [PMID: 23088156] - Yoshinori Asakawa, Agnieszka Ludwiczuk, Liva Harinantenaina, Masao Toyota, Mayumi Nishiki, Alicia Bardon, Kaeko Nii. Distribution of drimane sesquiterpenoids and tocopherols in liverworts, ferns and higher plants: Polygonaceae, Canellaceae and Winteraceae species.
Natural product communications.
2012 Jun; 7(6):685-92. doi:
. [PMID: 22816285] - Rajia Sultana, Rashadul Hossain, Achyut Adhikari, Zulfiqar Ali, Sammar Yousuf, Muhammad Iqbal Choudhary, Muhammad Yusuff Ali, Muhammad Shahed Zaman. Drimane-type sesquiterpenes from Polygonum hydropiper.
Planta medica.
2011 Nov; 77(16):1848-51. doi:
10.1055/s-0030-1271178. [PMID: 21674440] - Abraham Abebe Wube, Franz Bucar, Simon Gibbons, Kaleab Asres, Lauren Rattray, Simon L Croft. Antiprotozoal activity of drimane and coloratane sesquiterpenes towards Trypanosoma brucei rhodesiense and Plasmodium falciparum in vitro.
Phytotherapy research : PTR.
2010 Oct; 24(10):1468-72. doi:
10.1002/ptr.3126. [PMID: 20878696] - Min Xu, Marc Litaudon, Sabrina Krief, Marie-Thérèse Martin, John Kasenene, Bernard Kiremire, Vincent Dumontet, Françoise Guéritte. Ugandenial A, a new drimane-type sesquiterpenoid from Warburgia ugandensis.
Molecules (Basel, Switzerland).
2009 Sep; 14(10):3844-50. doi:
10.3390/molecules14103844. [PMID: 19924033] - Haixue Kuang, Chao Sun, Yanli Zhang, Yanlong Zhang, Dong Chen, Bingyou Yang, Yonggang Xia. Three drimane sesquiterpene glucoside from the aerial parts of Dryopteris fragrans (L.) schot.
Fitoterapia.
2009 Mar; 80(2):134-7. doi:
10.1016/j.fitote.2008.12.004. [PMID: 19167469] - Cailean Clarkson, Eliya V Madikane, Steen Honoré Hansen, Peter J Smith, Jerzy W Jaroszewski. HPLC-SPE-NMR characterization of sesquiterpenes in an antimycobacterial fraction from Warburgia salutaris.
Planta medica.
2007 Jun; 73(6):578-84. doi:
10.1055/s-2007-967187. [PMID: 17486536] - Liva Harinantenaina, Shigeru Takaoka. Cinnafragrins A-C, dimeric and trimeric drimane sesquiterpenoids from Cinnamosma fragrans, and structure revision of capsicodendrin.
Journal of natural products.
2006 Aug; 69(8):1193-7. doi:
10.1021/np0601298. [PMID: 16933874] - Abraham Abebe Wube, Simon Gibbons, Kaleab Asres, Bernhard Streit, Michael Adams, Rudolf Bauer, Franz Bucar. In vitro 12(S)-HETE and leukotriene metabolism inhibitory activity of sesquiterpenes of Warburgia ugandensis.
Planta medica.
2006 Jun; 72(8):754-6. doi:
10.1055/s-2006-931596. [PMID: 16732527] - Christian Starkenmann, Ludmila Luca, Yvan Niclass, Eric Praz, Didier Roguet. Comparison of volatile constituents of Persicaria odorata(Lour.) Soják (Polygonum odoratum Lour.) and Persicaria hydropiper L. Spach (Polygonum hydropiper L.).
Journal of agricultural and food chemistry.
2006 Apr; 54(8):3067-71. doi:
10.1021/jf0531611. [PMID: 16608232] - Angela Malheiros, Valdir Cechinel Filho, Clarisse B Schmitt, Rosendo A Yunes, Andrea Escalante, Laurq Svetaz, Susana Zacchino, Franco Delle Monache. Antifungal activity of drimane sesquiterpenes from Drimys brasiliensis using bioassay-guided fractionation.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
2005 Aug; 8(2):335-9. doi:
". [PMID: 16124945] - Benjamín Rodríguez, Nelson Zapata, Pilar Medina, Elisa Viñuela. A complete 1H and 13C NMR data assignment for four drimane sesquiterpenoids isolated from Drimys winterii.
Magnetic resonance in chemistry : MRC.
2005 Jan; 43(1):82-4. doi:
10.1002/mrc.1500. [PMID: 15468277] - Lawrence O Arot Manguro, Ivar Ugi, Rudolf Hermann, Peter Lemmen. Flavonol and drimane-type sesquiterpene glycosides of Warburgia stuhlmannii leaves.
Phytochemistry.
2003 Jun; 63(4):497-502. doi:
10.1016/s0031-9422(03)00105-5. [PMID: 12770606]