(+/-)-XYLOKETAL B (BioDeep_00000370961)
代谢物信息卡片
化学式: C20H26O5 (346.17801460000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1COC2(C)Oc3cc(O)c4c(c3CC12)OC1(C)OCC(C)C1C4
InChI: InChI=1S/C20H26O5/c1-10-9-23-20(4)14(10)5-12-16(21)7-17-13(18(12)25-20)6-15-11(2)8-22-19(15,3)24-17/h7,10-11,14-15,21H,5-6,8-9H2,1-4H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yichen Tong, Wentao Zhu, Tianzhi Wen, Zere Mukhamejanova, Fang Xu, Qi Xiang, Jiyan Pang. Xyloketal B Reverses Nutritional Hepatic Steatosis, Steatohepatitis, and Liver Fibrosis through Activation of the PPARα/PGC1α Signaling Pathway.
Journal of natural products.
2022 07; 85(7):1738-1750. doi:
10.1021/acs.jnatprod.2c00259. [PMID: 35749236] - Haifan Gong, Julia Bandura, Guan-Lei Wang, Zhong-Ping Feng, Hong-Shuo Sun. Xyloketal B: A marine compound with medicinal potential.
Pharmacology & therapeutics.
2022 02; 230(?):107963. doi:
10.1016/j.pharmthera.2021.107963. [PMID: 34375691] - Li-Yan Zhao, Jie Li, Xiong-Qing Huang, Guo-Hao Wang, Xiao-Fei Lv, Wei-Feng Meng, Wen-Liang Chen, Ji-Yan Pang, Yong-Cheng Lin, Hong-Shuo Sun, Guan-Lei Wang, Yao-Min Du. Xyloketal B exerts antihypertensive effect in renovascular hypertensive rats via the NO-sGC-cGMP pathway and calcium signaling.
Acta pharmacologica Sinica.
2018 May; 39(5):875-884. doi:
10.1038/aps.2018.12. [PMID: 29595193] - Jie-Bin Zhou, Ying-Lin Zheng, Yi-Xuan Zeng, Jia-Wei Wang, Zhong Pei, Ji-Yan Pang. Marine derived xyloketal derivatives exhibit anti-stress and anti-ageing effects through HSF pathway in Caenorhabditis elegans.
European journal of medicinal chemistry.
2018 Mar; 148(?):63-72. doi:
10.1016/j.ejmech.2018.02.028. [PMID: 29454917] - Youying Zhang, Tian Meng, Ling Zuo, Yu Bei, Qihao Zhang, Zhijian Su, Yadong Huang, Jiyan Pang, Qi Xiang, Hongtu Yang. Xyloketal B Attenuates Fatty Acid-Induced Lipid Accumulation via the SREBP-1c Pathway in NAFLD Models.
Marine drugs.
2017 Jun; 15(6):. doi:
10.3390/md15060163. [PMID: 28587208] - Li-Yan Zhao, Jie Li, Feng Yuan, Mei Li, Quan Zhang, Yun-Ying Huang, Ji-Yan Pang, Bin Zhang, Fang-Yun Sun, Hong-Shuo Sun, Qian Li, Lu Cao, Yu Xie, Yong-Cheng Lin, Jie Liu, Hong-Mei Tan, Guan-Lei Wang. Xyloketal B attenuates atherosclerotic plaque formation and endothelial dysfunction in apolipoprotein e deficient mice.
Marine drugs.
2015 Apr; 13(4):2306-26. doi:
10.3390/md13042306. [PMID: 25874925] - Junhui Su, Cui Chang, Qi Xiang, Zhi-Wei Zhou, Rong Luo, Lun Yang, Zhi-Xu He, Hongtu Yang, Jianan Li, Yu Bei, Jinmei Xu, Minjing Zhang, Qihao Zhang, Zhijian Su, Yadong Huang, Jiyan Pang, Shu-Feng Zhou. Xyloketal B, a marine compound, acts on a network of molecular proteins and regulates the activity and expression of rat cytochrome P450 3a: a bioinformatic and animal study.
Drug design, development and therapy.
2014; 8(?):2555-602. doi:
10.2147/dddt.s73476. [PMID: 25548518] - Wei Zhang, Yan Liu, Hongtu Yang, Zongyi Li, Yadong Huang, Zhongliang Xu, Yongcheng Lin, Qi Xiang, Jiyan Pang. A validated high-performance liquid chromatographic method with diode-array detection for the estimation of xyloketal B in rat plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2012 Feb; 885-886(?):24-9. doi:
10.1016/j.jchromb.2011.12.005. [PMID: 22222627]