3-Galloylgallocatechin (BioDeep_00000036380)
human metabolite PANOMIX_OTCML-2023
代谢物信息卡片
(2R,3S)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoic acid
化学式: C22H18O11 (458.0849078)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
InChI: InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21+/m0/s1
描述信息
Gallocatechin gallate (GCG) is the ester of gallocatechin and gallic acid and a type of catechin. It is an epimer of epigallocatechin gallate (EGCG). [Wikipedia]. Gallocatechin 3-gallate is found in many foods, some of which are common walnut, peanut, almond, and common hazelnut.
3-Galloylgallocatechin is found in almond. Gallocatechin gallate (GCG) is the ester of gallocatechin and gallic acid and a type of catechin. It is an epimer of epigallocatechin gallate (EGCG). (Wikipedia).
同义名列表
14 个代谢物同义名
(2R,3S)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoic acid; (2R,3S)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate; (+)-Gallocatechin-3-O-gallic acid; Gallocatechin 3-O-gallic acid; (+)-Gallocatechin 3-O-gallate; (+)-Gallocatechin-3-O-gallate; (+)-Gallocatechol gallic acid; Gallocatechin 3-gallic acid; Gallocatechin 3-O-gallate; (+)-Gallocatechol gallate; Gallocatechin 3-gallate; Gallocatechin-3-gallate; 3-Galloylgallocatechin; Gallocatechin gallate
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:156284
- PubChem: 5276890
- HMDB: HMDB0041598
- ChEMBL: CHEMBL126079
- KNApSAcK: C00008882
- foodb: FDB021740
- chemspider: 4440832
- CAS: 5127-64-0
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
37 个相关的物种来源信息
- 32201 Carya illinoinensis: 10.1021/JF061478A
- 171929 Anacardium occidentale: 10.1021/JF061478A
- 55513 Pistacia vera: 10.1021/JF061478A
- 3435 Persea americana: 10.1021/JF061478A
- 3818 Arachis hypogaea: 10.1021/JF061478A
- 3755 Prunus dulcis: 10.1021/JF061478A
- 3645 Bertholletia excelsa: 10.1021/JF061478A
- 51240 Juglans regia: 10.1021/JF061478A
- 13450 Corylus: 10.1021/JF061478A
- 4640 Musa: 10.1021/JF061478A
- 3625 Actinidia chinensis: 10.1021/JF061478A
- 4329 Macadamia: 10.1021/JF061478A
- 4615 Ananas comosus: 10.1021/JF061478A
- 3337 Pinus: 10.1021/JF061478A
- 4442 Camellia sinensis:
- 98504 Matricaria chamomilla: 10.1111/J.1365-2621.2005.TB08304.X
- 3498 Morus alba: 10.1016/J.FOODCHEM.2014.08.101
- 29760 Vitis vinifera: 10.1021/JF000316Q
- 32201 Carya illinoinensis: 10.1021/JF061478A
- 171929 Anacardium occidentale: 10.1021/JF061478A
- 55513 Pistacia vera: 10.1021/JF061478A
- 3435 Persea americana: 10.1021/JF061478A
- 3818 Arachis hypogaea: 10.1021/JF061478A
- 3755 Prunus dulcis: 10.1021/JF061478A
- 3645 Bertholletia excelsa: 10.1021/JF061478A
- 51240 Juglans regia: 10.1021/JF061478A
- 13450 Corylus: 10.1021/JF061478A
- 4640 Musa: 10.1021/JF061478A
- 3625 Actinidia chinensis: 10.1021/JF061478A
- 4329 Macadamia: 10.1021/JF061478A
- 4615 Ananas comosus: 10.1021/JF061478A
- 3337 Pinus: 10.1021/JF061478A
- 4442 Camellia sinensis:
- 98504 Matricaria chamomilla: 10.1111/J.1365-2621.2005.TB08304.X
- 3498 Morus alba: 10.1016/J.FOODCHEM.2014.08.101
- 29760 Vitis vinifera: 10.1021/JF000316Q
- 9606 Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ziqiong Zhou, Yan Li, Fangyuan Wang, Guanghao Zhu, Shenglan Qi, Haonan Wang, Yuhe Ma, Rong Zhu, Yuejuan Zheng, Guangbo Ge, Ping Wang. Bioactive components and mechanisms of Pu-erh tea in improving levodopa metabolism in rats through COMT inhibition.
Food & function.
2024 May; 15(10):5287-5299. doi:
10.1039/d4fo00538d. [PMID: 38639730] - Ting Xiao, Mengqi Cui, Caijuan Zheng, Peipei Zhang, Shanfa Ren, Jiali Bao, Dandi Gao, Ronghao Sun, Ming Wang, Jianping Lin, Liang Zhang, Mingjiang Li, Dongmei Li, Honggang Zhou, Cheng Yang. Both Baicalein and Gallocatechin Gallate Effectively Inhibit SARS-CoV-2 Replication by Targeting Mpro and Sepsis in Mice.
Inflammation.
2022 Jun; 45(3):1076-1088. doi:
10.1007/s10753-021-01602-z. [PMID: 34822072] - Kanane Sato, Shunya Saito, Kohsuke Endo, Masaru Kono, Taishin Kakei, Haruka Taketa, Megumi Kato, Shin Hamamoto, Matteo Grenzi, Alex Costa, Shintaro Munemasa, Yoshiyuki Murata, Yasuhiro Ishimaru, Nobuyuki Uozumi. Green Tea Catechins, (-)-Catechin Gallate, and (-)-Gallocatechin Gallate are Potent Inhibitors of ABA-Induced Stomatal Closure.
Advanced science (Weinheim, Baden-Wurttemberg, Germany).
2022 May; ?(?):e2201403. doi:
10.1002/advs.202201403. [PMID: 35524639] - Sunanta Wangkarn, Kate Grudpan, Chartchai Khanongnuch, Thanawat Pattananandecha, Sutasinee Apichai, Chalermpong Saenjum. Development of HPLC Method for Catechins and Related Compounds Determination and Standardization in Miang (Traditional Lanna Fermented Tea Leaf in Northern Thailand).
Molecules (Basel, Switzerland).
2021 Oct; 26(19):. doi:
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Molecules (Basel, Switzerland).
2021 Jun; 26(13):. doi:
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Journal of food science.
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Nature communications.
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Scientific reports.
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Biomolecules.
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Food chemistry.
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Food chemistry.
2018 Sep; 261(?):246-252. doi:
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Food & function.
2018 Sep; 9(9):4858-4864. doi:
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Food chemistry.
2018 Mar; 242(?):527-532. doi:
10.1016/j.foodchem.2017.09.094. [PMID: 29037724] - Xiong Gao, Xiaorong Lin, Xiaofei Li, Yuanyuan Zhang, Zhongzheng Chen, Bin Li. Cellular antioxidant, methylglyoxal trapping, and anti-inflammatory activities of cocoa tea (Camellia ptilophylla Chang).
Food & function.
2017 Aug; 8(8):2836-2846. doi:
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Scientific reports.
2017 07; 7(1):6947. doi:
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Food chemistry.
2017 Apr; 220(?):517-526. doi:
10.1016/j.foodchem.2016.09.047. [PMID: 27855934] - Milica M Pantelić, Dragana Č Dabić Zagorac, Sonja M Davidović, Slavica R Todić, Zoran S Bešlić, Uroš M Gašić, Živoslav Lj Tešić, Maja M Natić. Identification and quantification of phenolic compounds in berry skin, pulp, and seeds in 13 grapevine varieties grown in Serbia.
Food chemistry.
2016 Nov; 211(?):243-52. doi:
10.1016/j.foodchem.2016.05.051. [PMID: 27283628] - Xian Hui, Hui Liu, Fang-Lin Tian, Fei-Fei Li, Heng Li, Wen-Yun Gao. Inhibition of green tea and the catechins against 1-deoxy-d-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway.
Fitoterapia.
2016 Sep; 113(?):80-4. doi:
10.1016/j.fitote.2016.07.009. [PMID: 27439219] - Iva Boušová, Petra Matoušková, Hana Bártíková, Barbora Szotáková, Veronika Hanušová, Veronika Tománková, Eva Anzenbacherová, Barbora Lišková, Pavel Anzenbacher, Lenka Skálová. Influence of diet supplementation with green tea extract on drug-metabolizing enzymes in a mouse model of monosodium glutamate-induced obesity.
European journal of nutrition.
2016 Feb; 55(1):361-71. doi:
10.1007/s00394-015-0856-7. [PMID: 25663641] - Kaikai Li, Xuelin Zhou, Cheuk-Lun Liu, Xiaorong Yang, Xiaoqiang Han, Xianggang Shi, Xiaohong Song, Chuangxing Ye, Chun-hay Ko. Preparative separation of gallocatechin gallate from Camellia ptilophylla using macroporous resins followed by sephadex LH-20 column chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2016 Feb; 1011(?):6-13. doi:
10.1016/j.jchromb.2015.12.039. [PMID: 26744789] - Namrita Lall, Navneet Kishore, Saeideh Momtaz, Ahmed Hussein, Sanushka Naidoo, Mabatho Nqephe, Bridget Crampton. Extract from Ceratonia siliqua Exhibits Depigmentation Properties.
Phytotherapy research : PTR.
2015 Nov; 29(11):1729-36. doi:
10.1002/ptr.5420. [PMID: 26201055] - Yuan-Ting Zhu, Xiao-Yun Ren, Li Yuan, Yi-Ming Liu, Jian Liang, Xun Liao. Fast identification of lipase inhibitors in oolong tea by using lipase functionalised Fe3O4 magnetic nanoparticles coupled with UPLC-MS/MS.
Food chemistry.
2015 Apr; 173(?):521-6. doi:
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Molecules (Basel, Switzerland).
2013 Oct; 18(11):13530-45. doi:
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Journal of food science.
2012 Mar; 77(3):C298-302. doi:
10.1111/j.1750-3841.2011.02583.x. [PMID: 22329921] - Manar M Salem, Frederick H Davidorf, Mohamed H Abdel-Rahman. In vitro anti-uveal melanoma activity of phenolic compounds from the Egyptian medicinal plant Acacia nilotica.
Fitoterapia.
2011 Dec; 82(8):1279-84. doi:
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Food & function.
2011 Jan; 2(1):28-38. doi:
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Archives of oral biology.
2011 Jan; 56(1):48-53. doi:
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Journal of neurochemistry.
2008 Oct; 107(1):218-29. doi:
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Lipids.
2008 May; 43(5):419-29. doi:
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Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2007 Feb; 23(2):157-63. doi:
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Oral microbiology and immunology.
2004 Apr; 19(2):118-20. doi:
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Pharmacology & toxicology.
2003 May; 92(5):234-41. doi:
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Journal of immunology (Baltimore, Md. : 1950).
2003 Apr; 170(8):4335-41. doi:
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Journal of agricultural and food chemistry.
2002 Apr; 50(8):2418-22. doi:
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Archives of pharmacal research.
2001 Aug; 24(4):292-6. doi:
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Nutrition and cancer.
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Analytical biochemistry.
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