3'-O-Methylcatechin (BioDeep_00000036362)

   

human metabolite blood metabolite


代谢物信息卡片


(2R,3S)-2-(3,4-dihydroxyphenyl)-3-methoxy-3,4-dihydro-2H-1-benzopyran-5,7-diol

化学式: C16H16O6 (304.0946836)
中文名称: 美西达醇
谱图信息: 最多检出来源 Homo sapiens(blood) 97.83%

分子结构信息

SMILES: COC1=C(O)C=CC(=C1)[C@H]1OC2=C(C[C@@H]1O)C(O)=CC(O)=C2
InChI: InChI=1S/C16H16O6/c1-21-15-7-10-12(19)5-9(17)6-14(10)22-16(15)8-2-3-11(18)13(20)4-8/h2-6,15-20H,7H2,1H3/t15-,16+/m0/s1

描述信息

3-O-Methylcatechin is a constituent of Pinus sylvestris (Scotch pine). 3-O-Methylcatechin is a flavonoid metabolite.
C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent
D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents
Constituent of Pinus sylvestris (Scotch pine)
D004791 - Enzyme Inhibitors

同义名列表

12 个代谢物同义名

(2R,3S)-2-(3,4-dihydroxyphenyl)-3-methoxy-3,4-dihydro-2H-1-benzopyran-5,7-diol; (2R,5S)-2-TRICHLOROMETHYL-3-OXA-1-AZABICYCLO[3.3.0]OCTAN-4-ONE; 3-O-Methylcatechin, (2R-trans)-isomer; 3,4,5,7-Tetrahydroxy-3-methoxyflavan; 2-Methoxy-5,7,3,4-tetrahydroxyflavan; 3-O-Methyl-(+)-catechin; 3’-O-methylcatechin; 3-O-Methylcatechin; 3-O-methylcatechin; 3-Methylcatechin; Meciadanol; 3-Mthf



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • J L Donovan, J R Bell, S Kasim-Karakas, J B German, R L Walzem, R J Hansen, A L Waterhouse. Catechin is present as metabolites in human plasma after consumption of red wine. The Journal of nutrition. 1999 Sep; 129(9):1662-8. doi: 10.1093/jn/129.9.1662. [PMID: 10460201]
  • D M Gott, L A Griffiths. Effects of antibiotic pretreatments on the metabolism and excretion of [U14C](+)-catechin [( U14C](+)-cyanidanol-3) and its metabolite, 3'-0-methyl-(+)-catechin. Xenobiotica; the fate of foreign compounds in biological systems. 1987 Apr; 17(4):423-34. doi: 10.3109/00498258709043949. [PMID: 3604252]
  • R J Gryglewski, R Korbut, J Robak, J Swies. On the mechanism of antithrombotic action of flavonoids. Biochemical pharmacology. 1987 Feb; 36(3):317-22. doi: 10.1016/0006-2952(87)90288-7. [PMID: 3101704]
  • A M Hackett, L A Griffiths, M Wermeille. The quantitative disposition of 3-O-methyl-(+)-[U-14C]catechin in man following oral administration. Xenobiotica; the fate of foreign compounds in biological systems. 1985 Nov; 15(11):907-14. doi: 10.3109/00498258509045044. [PMID: 4082631]
  • A M Hackett, L A Griffiths. The effects of an experimental hepatitis on the metabolic disposition of 3-o-(+)-[14C]methylcatechin in the rat. Drug metabolism and disposition: the biological fate of chemicals. 1983 Nov; 11(6):602-6. doi: NULL. [PMID: 6140147]
  • A M Hackett, L A Griffiths. The disposition of 3-O-methyl-(+)-catechin in the rat and the marmoset following oral administration. European journal of drug metabolism and pharmacokinetics. 1983; 8(1):35-42. doi: 10.1007/bf03189579. [PMID: 6407839]
  • M Wermeille, E Turin, L A Griffiths. Identification of the major urinary metabolites of (+)-catechin and 3-O-methyl-(+)-catechin in man. European journal of drug metabolism and pharmacokinetics. 1983; 8(1):77-84. doi: 10.1007/bf03189584. [PMID: 6861797]
  • A M Hackett, L A Griffiths. The metabolism and excretion of 3-O-methyl-(+)-catechin in the rat, mouse, and marmoset. Drug metabolism and disposition: the biological fate of chemicals. 1981 Jan; 9(1):54-9. doi: NULL. [PMID: 6111433]