7-Azaindole (BioDeep_00000362834)

   


代谢物信息卡片


7-Azaindole

化学式: C7H6N2 (118.0531)
中文名称: 7-氮杂吲哚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC2=C(NC=C2)N=C1
InChI: InChI=1S/C7H6N2/c1-2-6-3-5-9-7(6)8-4-1/h1-5H,(H,8,9)

描述信息

COVID info from PDB, Protein Data Bank
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

2 个代谢物同义名

7-Azaindole; 7-Azaindole



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Johannes Pilakowski, Georg Baumann, Yung-Hsin Shih, Tobias Meckel, Boris Schmidt. Design, synthesis and biological evaluation of novel aminopyrazole- and 7-azaindole-based Nek1 inhibitors and their effects on zebrafish kidney development. Bioorganic & medicinal chemistry letters. 2021 12; 53(?):128418. doi: 10.1016/j.bmcl.2021.128418. [PMID: 34715306]
  • Adrian A Doerr, Frederike Nordmeier, Nadja Walle, Matthias W Laschke, Michael D Menger, Peter H Schmidt, Nadine Schaefer, Markus R Meyer. Can a Recently Developed Pig Model Be Used for In Vivo Metabolism Studies of 7-Azaindole-Derived Synthetic Cannabinoids? A Study Using 5F-MDMB-P7AICA. Journal of analytical toxicology. 2021 Jul; 45(6):593-604. doi: 10.1093/jat/bkaa122. [PMID: 32886783]
  • Nadja Walle, Frederike Nordmeier, Adrian A Doerr, Benjamin Peters, Matthias W Laschke, Michael D Menger, Peter H Schmidt, Markus R Meyer, Nadine Schaefer. Comparison of in vitro and in vivo models for the elucidation of metabolic patterns of 7-azaindole-derived synthetic cannabinoids exemplified using cumyl-5F-P7AICA. Drug testing and analysis. 2021 Jan; 13(1):74-90. doi: 10.1002/dta.2899. [PMID: 32678962]
  • Arianna Giorgetti, Lukas Mogler, Belal Haschimi, Sebastian Halter, Florian Franz, Folker Westphal, Svenja Fischmann, Jan Riedel, Michael Pütz, Volker Auwärter. Detection and phase I metabolism of the 7-azaindole-derived synthetic cannabinoid 5F-AB-P7AICA including a preliminary pharmacokinetic evaluation. Drug testing and analysis. 2020 Jan; 12(1):78-91. doi: 10.1002/dta.2692. [PMID: 31476105]
  • Jian Wu, Shenghong Kang, Baoan Song, Deyu Hu, Ming He, Linhong Jin, Song Yang. Synthesis and antibacterial activity against ralstonia solanacearum for novel hydrazone derivatives containing a pyridine moiety. Chemistry Central journal. 2012 Apr; 6(?):28. doi: 10.1186/1752-153x-6-28. [PMID: 22483270]
  • Paul Bamborough, Murray J Brown, John A Christopher, Chun-wa Chung, Geoff W Mellor. Selectivity of kinase inhibitor fragments. Journal of medicinal chemistry. 2011 Jul; 54(14):5131-43. doi: 10.1021/jm200349b. [PMID: 21699136]
  • Alexander Kyrychenko, Jacek Waluk. Distribution and favorable binding sites of pyrroloquinoline and its analogues in a lipid bilayer studied by molecular dynamics simulations. Biophysical chemistry. 2008 Aug; 136(2-3):128-35. doi: 10.1016/j.bpc.2008.05.006. [PMID: 18556112]
  • Jérome Guillard, Maÿlis Decrop, Nathalie Gallay, Claire Espanel, Elodie Boissier, Olivier Herault, Marie-Claude Viaud-Massuard. Synthesis and biological evaluation of 7-azaindole derivatives, synthetic cytokinin analogues. Bioorganic & medicinal chemistry letters. 2007 Apr; 17(7):1934-7. doi: 10.1016/j.bmcl.2007.01.033. [PMID: 17300934]
  • Moustafa M Ghorab, Eman Noaman, Magda M F Ismail, Helmy I Heiba, Yousry A Ammar, Marwa Y Sayed. Novel antitumor and radioprotective sulfonamides containing pyrrolo [2,3-d]pyrimidines. Arzneimittel-Forschung. 2006; 56(6):405-13. doi: 10.1055/s-0031-1296742. [PMID: 16889123]
  • Brian Dyck, Dimitri E Grigoriadis, Raymond S Gross, Zhiqiang Guo, Mustapha Haddach, Dragan Marinkovic, James R McCarthy, Manisha Moorjani, Collin F Regan, John Saunders, Michael K Schwaebe, Tomas Szabo, John P Williams, Xiaohu Zhang, Haig Bozigian, Ta Kung Chen. Potent, orally active corticotropin-releasing factor receptor-1 antagonists containing a tricyclic pyrrolopyridine or pyrazolopyridine core. Journal of medicinal chemistry. 2005 Jun; 48(12):4100-10. doi: 10.1021/jm050070m. [PMID: 15943483]