ubiquinol-9 (BioDeep_00000359150)
代谢物信息卡片
ubiquinol-9
化学式: C54H84O4 (796.6369264)
中文名称:
谱图信息:
最多检出来源 Viridiplantae(plant) 49.05%
分子结构信息
SMILES: CC1=C(C(=C(C(=C1O)OC)OC)O)CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C
InChI: InChI=1S/C54H84O4/c1-40(2)22-14-23-41(3)24-15-25-42(4)26-16-27-43(5)28-17-29-44(6)30-18-31-45(7)32-19-33-46(8)34-20-35-47(9)36-21-37-48(10)38-39-50-49(11)51(55)53(57-12)54(58-13)52(50)56/h22,24,26,28,30,32,34,36,38,55-56H,14-21,23,25,27,29,31,33,35,37,39H2,1-13H3/b41-24+,42-26+,43-28+,44-30+,45-32+,46-34+,47-36+,48-38+
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:84424
- PubChem: 45281170
- PubChem: 75110389
- MetaCyc: CPD-9957
- CAS: 5677-54-3
- PMhub: MS000172978
- MetaboLights: MTBLC84424
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
代谢反应
144 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(144)
- trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
9,9'-di-cis-ζ-carotene + an electron-transfer quinone ⟶ 7,9,9'-cis-neurosporene + an electron-transfer quinol - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
prolycopene ⟶ all-trans-lycopene - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
prolycopene ⟶ all-trans-lycopene - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
prolycopene ⟶ all-trans-lycopene - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
prolycopene ⟶ all-trans-lycopene - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
prolycopene ⟶ all-trans-lycopene - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
prolycopene ⟶ all-trans-lycopene - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
prolycopene ⟶ all-trans-lycopene - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
prolycopene ⟶ all-trans-lycopene - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
prolycopene ⟶ all-trans-lycopene - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
prolycopene ⟶ all-trans-lycopene - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
prolycopene ⟶ all-trans-lycopene - superpathway of carotenoid biosynthesis in plants:
β-carotene + H+ + O2 + a reduced ferredoxin [iron-sulfur] cluster ⟶ β-cryptoxanthin + H2O + an oxidized ferredoxin [iron-sulfur] cluster - superpathway of carotenoid biosynthesis in plants:
β-cryptoxanthin + H+ + O2 + a reduced ferredoxin [iron-sulfur] cluster ⟶ H2O + an oxidized ferredoxin [iron-sulfur] cluster + zeaxanthin - superpathway of carotenoid biosynthesis in plants:
β-carotene + H+ + O2 + a reduced ferredoxin [iron-sulfur] cluster ⟶ β-cryptoxanthin + H2O + an oxidized ferredoxin [iron-sulfur] cluster - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
prolycopene ⟶ all-trans-lycopene - superpathway of carotenoid biosynthesis in plants:
β-carotene + H+ + O2 + a reduced ferredoxin [iron-sulfur] cluster ⟶ β-cryptoxanthin + H2O + an oxidized ferredoxin [iron-sulfur] cluster - superpathway of carotenoid biosynthesis in plants:
β-carotene + H+ + O2 + a reduced ferredoxin [iron-sulfur] cluster ⟶ β-cryptoxanthin + H2O + an oxidized ferredoxin [iron-sulfur] cluster - trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria):
9,9'-di-cis-ζ-carotene + an electron-transfer quinone ⟶ 7,9,9'-cis-neurosporene + an electron-transfer quinol - superpathway of carotenoid biosynthesis in plants:
γ-carotene ⟶ β-carotene - superpathway of carotenoid biosynthesis in plants:
γ-carotene ⟶ β-carotene - superpathway of carotenoid biosynthesis in plants:
β-carotene + H+ + O2 + a reduced ferredoxin [iron-sulfur] cluster ⟶ β-cryptoxanthin + H2O + an oxidized ferredoxin [iron-sulfur] cluster - superpathway of carotenoid biosynthesis in plants:
β-carotene + H+ + O2 + a reduced ferredoxin [iron-sulfur] cluster ⟶ β-cryptoxanthin + H2O + an oxidized ferredoxin [iron-sulfur] cluster - superpathway of carotenoid biosynthesis in plants:
β-carotene + H+ + O2 + a reduced ferredoxin [iron-sulfur] cluster ⟶ β-cryptoxanthin + H2O + an oxidized ferredoxin [iron-sulfur] cluster - superpathway of carotenoid biosynthesis in plants:
β-cryptoxanthin + H+ + O2 + a reduced ferredoxin [iron-sulfur] cluster ⟶ H2O + an oxidized ferredoxin [iron-sulfur] cluster + zeaxanthin - superpathway of carotenoid biosynthesis in plants:
β-carotene + H+ + O2 + a reduced ferredoxin [iron-sulfur] cluster ⟶ β-cryptoxanthin + H2O + an oxidized ferredoxin [iron-sulfur] cluster - aerobic respiration III (alternative oxidase pathway):
UQ + succinate ⟶ UQH2 + fumarate - aerobic respiration I (cytochrome c):
UQ + succinate ⟶ UQH2 + fumarate - NAD(P)/NADPH interconversion:
H2O + NADP+ ⟶ NAD+ + phosphate - glucose and glucose-1-phosphate degradation:
D-glucopyranose + UQ ⟶ D-glucono-1,5-lactone + UQH2 - aerobic respiration III (alternative oxidase pathway):
UQ + succinate ⟶ UQH2 + fumarate - glucose and glucose-1-phosphate degradation:
ATP + D-glucopyranose ⟶ ADP + D-glucopyranose 6-phosphate + H+ - NAD/NADH phosphorylation and dephosphorylation:
NAD+ + NADPH ⟶ NADH + NADP+ - aerobic respiration I (cytochrome c):
UQ + succinate ⟶ UQH2 + fumarate - glucose and glucose-1-phosphate degradation:
α-D-glucopyranose 1-phosphate + H2O ⟶ D-glucopyranose + phosphate - aerobic respiration III (alternative oxidase pathway):
UQ + succinate ⟶ UQH2 + fumarate - NAD/NADH phosphorylation and dephosphorylation:
NAD+ + NADPH ⟶ NADH + NADP+ - L-proline degradation:
H2O + L-glutamate-5-semialdehyde + NAD+ ⟶ H+ + NADH + glu - glycerol-3-phosphate shuttle:
sn-glycerol 3-phosphate + NAD+ ⟶ DHAP + H+ + NADH - L-Nδ-acetylornithine biosynthesis:
2-oxoglutarate + L-ornithine ⟶ L-glutamate-5-semialdehyde + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - glycerol degradation I:
ATP + glycerol ⟶ sn-glycerol 3-phosphate + ADP + H+ - aerobic respiration I (cytochrome c):
UQ + succinate ⟶ UQH2 + fumarate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - NAD/NADH phosphorylation and dephosphorylation:
NAD+ + NADPH ⟶ NADH + NADP+ - aerobic respiration III (alternative oxidase pathway):
UQ + succinate ⟶ UQH2 + fumarate - aerobic respiration I (cytochrome c):
UQ + succinate ⟶ UQH2 + fumarate - glucose and glucose-1-phosphate degradation:
D-glucopyranose + UQ ⟶ D-glucono-1,5-lactone + UQH2 - aerobic respiration III (alternative oxidase pathway):
UQ + succinate ⟶ UQH2 + fumarate - aerobic respiration I (cytochrome c):
UQ + succinate ⟶ UQH2 + fumarate - NAD/NADH phosphorylation and dephosphorylation:
H2O + NADP+ ⟶ NAD+ + phosphate - glucose and glucose-1-phosphate degradation:
α-D-glucopyranose 1-phosphate + H2O ⟶ D-glucopyranose + phosphate - NAD/NADH phosphorylation and dephosphorylation:
ATP + NAD+ ⟶ ADP + H+ + NADP+ - aerobic respiration III (alternative oxidase pathway):
UQ + succinate ⟶ UQH2 + fumarate - glucose and glucose-1-phosphate degradation:
α-D-glucopyranose 1-phosphate + H2O ⟶ D-glucopyranose + phosphate - aerobic respiration I (cytochrome c):
UQ + succinate ⟶ UQH2 + fumarate - methylglyoxal degradation I:
(R)-lactate + UQ ⟶ UQH2 + pyruvate - aerobic respiration III (alternative oxidase pathway):
UQ + succinate ⟶ UQH2 + fumarate - glucose and glucose-1-phosphate degradation:
ATP + D-glucopyranose ⟶ ADP + D-glucopyranose 6-phosphate + H+ - aerobic respiration I (cytochrome c):
UQ + succinate ⟶ UQH2 + fumarate - NAD(P)/NADPH interconversion:
NAD+ + NADPH ⟶ NADH + NADP+ - aerobic respiration I (cytochrome c):
UQ + succinate ⟶ UQH2 + fumarate - NAD/NADH phosphorylation and dephosphorylation:
ATP + NAD+ ⟶ ADP + H+ + NADP+ - glucose and glucose-1-phosphate degradation:
D-glucono-1,5-lactone + H2O ⟶ D-gluconate + H+ - aerobic respiration III (alternative oxidase pathway):
UQ + succinate ⟶ UQH2 + fumarate - NAD/NADH phosphorylation and dephosphorylation:
H2O + NADP+ ⟶ NAD+ + phosphate - glucose and glucose-1-phosphate degradation:
D-glucono-1,5-lactone + H2O ⟶ D-gluconate + H+ - aerobic respiration III (alternative oxidase pathway):
UQ + succinate ⟶ UQH2 + fumarate - aerobic respiration I (cytochrome c):
UQ + succinate ⟶ UQH2 + fumarate - methylglyoxal degradation I:
(R)-lactate + UQ ⟶ UQH2 + pyruvate - NAD(P)/NADPH interconversion:
NAD+ + NADPH ⟶ NADH + NADP+ - glucose and glucose-1-phosphate degradation:
D-glucono-1,5-lactone + H2O ⟶ D-gluconate + H+ - aerobic respiration III (alternative oxidase pathway):
UQ + succinate ⟶ UQH2 + fumarate - aerobic respiration I (cytochrome c):
UQ + succinate ⟶ UQH2 + fumarate - NAD/NADH phosphorylation and dephosphorylation:
NAD+ + NADPH ⟶ NADH + NADP+ - glucose and glucose-1-phosphate degradation:
D-glucono-1,5-lactone + H2O ⟶ D-gluconate + H+ - aerobic respiration III (alternative oxidase pathway):
H+ + NADH + UQ ⟶ H+ + NAD+ + UQH2 - aerobic respiration I (cytochrome c):
H+ + NADH + UQ ⟶ H+ + NAD+ + UQH2 - aerobic respiration I (cytochrome c):
UQH2 + an oxidized c-type cytochrome ⟶ H+ + UQ + a reduced c-type cytochrome - glucose and glucose-1-phosphate degradation:
D-glucopyranose + UQ ⟶ D-glucono-1,5-lactone + UQH2 - aerobic respiration III (alternative oxidase pathway):
UQ + succinate ⟶ UQH2 + fumarate - NAD/NADH phosphorylation and dephosphorylation:
H+ + NADH + UQ ⟶ H+ + NAD+ + UQH2 - L-Nδ-acetylornithine biosynthesis:
(S)-1-pyrroline-5-carboxylate + H+ + H2O ⟶ L-glutamate-5-semialdehyde - L-citrulline biosynthesis:
(S)-1-pyrroline-5-carboxylate + H+ + H2O ⟶ L-glutamate-5-semialdehyde - L-proline degradation:
(S)-1-pyrroline-5-carboxylate + H+ + H2O ⟶ L-glutamate-5-semialdehyde - L-Nδ-acetylornithine biosynthesis:
2-oxoglutarate + L-ornithine ⟶ L-glutamate-5-semialdehyde + glu - L-proline degradation I:
H2O + L-glutamate-5-semialdehyde + NAD+ ⟶ H+ + NADH + glu - L-proline degradation:
H2O + L-glutamate-5-semialdehyde + NAD+ ⟶ H+ + NADH + glu - L-Nδ-acetylornithine biosynthesis:
2-oxoglutarate + L-ornithine ⟶ L-glutamate-5-semialdehyde + glu - L-proline degradation:
H2O + L-glutamate-5-semialdehyde + NAD+ ⟶ H+ + NADH + glu - L-Nδ-acetylornithine biosynthesis:
2-oxoglutarate + L-ornithine ⟶ L-glutamate-5-semialdehyde + glu - L-proline degradation:
H2O + L-glutamate-5-semialdehyde + NAD+ ⟶ H+ + NADH + glu - L-Nδ-acetylornithine biosynthesis:
2-oxoglutarate + L-ornithine ⟶ L-glutamate-5-semialdehyde + glu - L-proline degradation:
H2O + L-glutamate-5-semialdehyde + NAD+ ⟶ H+ + NADH + glu - L-Nδ-acetylornithine biosynthesis:
H2O + arg ⟶ L-ornithine + urea - L-proline degradation I:
H2O + L-glutamate-5-semialdehyde + NAD+ ⟶ H+ + NADH + glu - L-Nδ-acetylornithine biosynthesis:
H2O + arg ⟶ L-ornithine + urea - L-Nδ-acetylornithine biosynthesis:
H2O + arg ⟶ L-ornithine + urea - L-proline degradation:
H2O + L-glutamate-5-semialdehyde + NAD+ ⟶ H+ + NADH + glu - L-proline degradation:
H2O + L-glutamate-5-semialdehyde + NAD+ ⟶ H+ + NADH + glu - L-Nδ-acetylornithine biosynthesis:
H2O + arg ⟶ L-ornithine + urea - L-Nδ-acetylornithine biosynthesis:
H2O + arg ⟶ L-ornithine + urea - L-proline degradation:
H2O + L-glutamate-5-semialdehyde + NAD+ ⟶ H+ + NADH + glu - L-Nδ-acetylornithine biosynthesis:
H2O + arg ⟶ L-ornithine + urea - L-proline degradation I:
H2O + L-glutamate-5-semialdehyde + NAD+ ⟶ H+ + NADH + glu - L-citrulline biosynthesis:
H2O + arg ⟶ L-ornithine + urea - L-citrulline biosynthesis:
H2O + arg ⟶ L-ornithine + urea - L-proline degradation:
H2O + L-glutamate-5-semialdehyde + NAD+ ⟶ H+ + NADH + glu - L-citrulline biosynthesis:
H2O + arg ⟶ L-ornithine + urea - L-Nδ-acetylornithine biosynthesis:
H2O + arg ⟶ L-ornithine + urea - L-citrulline biosynthesis:
an electron-transfer quinone + pro ⟶ (S)-1-pyrroline-5-carboxylate + H+ + an electron-transfer quinol - L-proline degradation:
an electron-transfer quinone + pro ⟶ (S)-1-pyrroline-5-carboxylate + H+ + an electron-transfer quinol - L-Nδ-acetylornithine biosynthesis:
an electron-transfer quinone + pro ⟶ (S)-1-pyrroline-5-carboxylate + H+ + an electron-transfer quinol - superpathway of L-citrulline metabolism:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + phosphate - L-citrulline biosynthesis:
H2O + arg ⟶ L-ornithine + urea - L-citrulline biosynthesis:
H2O + arg ⟶ L-ornithine + urea - L-citrulline biosynthesis:
H2O + gln ⟶ H+ + ammonia + glu - L-citrulline biosynthesis:
H2O + gln ⟶ H+ + ammonia + glu - glucose and glucose-1-phosphate degradation:
α-D-glucopyranose 1-phosphate + H2O ⟶ D-glucopyranose + phosphate - glucose and glucose-1-phosphate degradation:
D-glucono-1,5-lactone + H2O ⟶ D-gluconate + H+ - glycerophosphodiester degradation:
H2O + a glycerophosphodiester ⟶ sn-glycerol 3-phosphate + H+ + an alcohol - glycerol degradation I:
ATP + glycerol ⟶ sn-glycerol 3-phosphate + ADP + H+ - UMP biosynthesis I:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - NAD/NADH phosphorylation and dephosphorylation:
H+ + NADH + UQ ⟶ H+ + NAD+ + UQH2 - aerobic respiration I (cytochrome c):
UQH2 + an oxidized c-type cytochrome ⟶ H+ + UQ + a reduced c-type cytochrome - methylglyoxal degradation I:
(R)-S-lactoylglutathione ⟶ glutathione + methylglyoxal - L-lysine degradation I:
5-aminopentanal + H2O + NAD+ ⟶ 5-aminopentanoate + H+ + NADH - glycerol-3-phosphate shuttle:
sn-glycerol 3-phosphate + an electron-transfer quinone ⟶ DHAP + an electron-transfer quinol - aerobic respiration III (alternative oxidase pathway):
O2 + UQH2 ⟶ H2O + UQ - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - superpathway of glyoxylate cycle and fatty acid degradation:
O2 + a 2,3,4-saturated fatty acyl CoA ⟶ a (2E)-2-enoyl-CoA + hydrogen peroxide - NAD/NADH phosphorylation and dephosphorylation:
NAD+ + NADPH ⟶ NADH + NADP+ - glycerol degradation I:
ATP + glycerol ⟶ sn-glycerol 3-phosphate + ADP + H+ - glycerol-3-phosphate shuttle:
sn-glycerol 3-phosphate + NAD+ ⟶ DHAP + H+ + NADH - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - aerobic respiration I (cytochrome c):
UQ + succinate ⟶ UQH2 + fumarate - superpathway of glyoxylate cycle and fatty acid degradation:
O2 + a 2,3,4-saturated fatty acyl CoA ⟶ a trans-2-enoyl-CoA + hydrogen peroxide - methylglyoxal degradation I:
(R)-lactate + UQ ⟶ UQH2 + pyruvate - aerobic respiration III (alternative oxidase pathway):
UQ + succinate ⟶ UQH2 + fumarate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - glycerophosphodiester degradation:
H2O + a glycerophosphodiester ⟶ sn-glycerol 3-phosphate + H+ + an alcohol
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Youssef W Naguib, Sanjib Saha, Jessica M Skeie, Timothy Acri, Kareem Ebeid, Somaya Abdel-Rahman, Sandeep Kesh, Gregory A Schmidt, Darryl Y Nishimura, Jeffrey A Banas, Min Zhu, Mark A Greiner, Aliasger K Salem. Solubilized ubiquinol for preserving corneal function.
Biomaterials.
2021 08; 275(?):120842. doi:
10.1016/j.biomaterials.2021.120842. [PMID: 34087583] - Mathias J Holmberg, Lars W Andersen, Ari Moskowitz, Katherine M Berg, Michael N Cocchi, Maureen Chase, Xiaowen Liu, Duncan M Kuhn, Anne V Grossestreuer, Anne Kirstine Hoeyer-Nielsen, Hans Kirkegaard, Michael W Donnino. Ubiquinol (reduced coenzyme Q10) as a metabolic resuscitator in post-cardiac arrest: A randomized, double-blind, placebo-controlled trial.
Resuscitation.
2021 05; 162(?):388-395. doi:
10.1016/j.resuscitation.2021.01.041. [PMID: 33577964] - Agustin J Ruiz, Ahmed Tibary, Robert A Heaton, Iain P Hargreaves, Desmond P Leadon, Warwick M Bayly. Effects of Feeding Coenzyme Q10-Ubiquinol on Plasma Coenzyme Q10 Concentrations and Semen Quality in Stallions.
Journal of equine veterinary science.
2021 01; 96(?):103303. doi:
10.1016/j.jevs.2020.103303. [PMID: 33349408] - Francesca Cateni, Marina Zacchigna, Giuseppe Procida. Synthesis and controlled drug delivery studies of a novel Ubiquinol-Polyethylene glycol-Vitamin E adduct.
Bioorganic chemistry.
2020 12; 105(?):104329. doi:
10.1016/j.bioorg.2020.104329. [PMID: 33068813] - Patrick Orlando, Jacopo Sabbatinelli, Sonia Silvestri, Fabio Marcheggiani, Ilenia Cirilli, Phiwayinkosi Vusi Dludla, Alberto Molardi, Francesco Nicolini, Luca Tiano. Ubiquinol supplementation in elderly patients undergoing aortic valve replacement: biochemical and clinical aspects.
Aging.
2020 07; 12(15):15514-15531. doi:
10.18632/aging.103742. [PMID: 32741773] - Louise Injarabian, Marc Scherlinger, Anne Devin, Stéphane Ransac, Jens Lykkesfeldt, Benoit S Marteyn. Ascorbate maintains a low plasma oxygen level.
Scientific reports.
2020 06; 10(1):10659. doi:
10.1038/s41598-020-67778-w. [PMID: 32606354] - Kei Mizuno, Akihiro T Sasaki, Kyosuke Watanabe, Yasuyoshi Watanabe. Ubiquinol-10 Intake Is Effective in Relieving Mild Fatigue in Healthy Individuals.
Nutrients.
2020 Jun; 12(6):. doi:
10.3390/nu12061640. [PMID: 32498248] - Jacopo Sabbatinelli, Patrick Orlando, Roberta Galeazzi, Sonia Silvestri, Ilenia Cirilli, Fabio Marcheggiani, Phiwayinkosi V Dludla, Angelica Giuliani, Anna Rita Bonfigli, Laura Mazzanti, Fabiola Olivieri, Roberto Antonicelli, Luca Tiano. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
Nutrients.
2020 Apr; 12(4):. doi:
10.3390/nu12041098. [PMID: 32326664] - Enyong Dai, Wenlong Zhang, Dan Cong, Rui Kang, Jing Wang, Daolin Tang. AIFM2 blocks ferroptosis independent of ubiquinol metabolism.
Biochemical and biophysical research communications.
2020 03; 523(4):966-971. doi:
10.1016/j.bbrc.2020.01.066. [PMID: 31964528] - T N Fedorova, V S Gusakov, A A Devyatov, O A Muzichuk, A V Lopachev, M A Belousova, S L Stvolinskii, O V Povarova, M V Gulyaev, O S Medvedev, V A Tutelyan. [Neuroprotective mechanisms of the ubiquinol action in experimental focal ischemia].
Biomeditsinskaia khimiia.
2020 Feb; 66(2):145-150. doi:
10.18097/pbmc20206602145. [PMID: 32420895] - Anna Gvozdjáková, Jarmila Kucharská, Branislav Kura, Ol'ga Vančová, Zuzana Rausová, Zuzana Sumbalová, Ol'ga Uličná, Ján Slezák. A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats.
Canadian journal of physiology and pharmacology.
2020 Jan; 98(1):29-34. doi:
10.1139/cjpp-2019-0281. [PMID: 31536712] - Huan-Chieh Chen, Chi-Chang Huang, Tien-Jen Lin, Mei-Chich Hsu, Yi-Ju Hsu. Ubiquinol Supplementation Alters Exercise Induced Fatigue by Increasing Lipid Utilization in Mice.
Nutrients.
2019 Oct; 11(11):. doi:
10.3390/nu11112550. [PMID: 31652711] - Guillermo López-Lluch, Jesús Del Pozo-Cruz, Ana Sánchez-Cuesta, Ana Belén Cortés-Rodríguez, Plácido Navas. Bioavailability of coenzyme Q10 supplements depends on carrier lipids and solubilization.
Nutrition (Burbank, Los Angeles County, Calif.).
2019 01; 57(?):133-140. doi:
10.1016/j.nut.2018.05.020. [PMID: 30153575] - Sho Suzuki, Takuji Gotoda, Chika Kusano, Hisatomo Ikehara, Yo Miyakoshi, Kenji Fujii. Effect of Ubiquinol Intake on Defecation Frequency and Stool Form: A Prospective, Double-Blinded, Randomized Control Study.
Journal of medicinal food.
2019 Jan; 22(1):81-86. doi:
10.1089/jmf.2018.4233. [PMID: 30192695] - Patrick Orlando, Sonia Silvestri, Roberta Galeazzi, Roberto Antonicelli, Fabio Marcheggiani, Ilenia Cirilli, Tiziana Bacchetti, Luca Tiano. Effect of ubiquinol supplementation on biochemical and oxidative stress indexes after intense exercise in young athletes.
Redox report : communications in free radical research.
2018 Dec; 23(1):136-145. doi:
10.1080/13510002.2018.1472924. [PMID: 29734881] - Ying Zhang, Jin Liu, Xiao-Qiang Chen, C-Y Oliver Chen. Ubiquinol is superior to ubiquinone to enhance Coenzyme Q10 status in older men.
Food & function.
2018 Nov; 9(11):5653-5659. doi:
10.1039/c8fo00971f. [PMID: 30302465] - Fong-Lin Chen, Po-Sheng Chang, Yi-Chin Lin, Ping-Ting Lin. A Pilot Clinical Study of Liquid Ubiquinol Supplementation on Cardiac Function in Pediatric Dilated Cardiomyopathy.
Nutrients.
2018 Nov; 10(11):. doi:
10.3390/nu10111697. [PMID: 30405022] - Javier Frontiñán-Rubio, Francisco J Sancho-Bielsa, Juan R Peinado, Frank M LaFerla, Lydia Giménez-Llort, Mario Durán-Prado, Francisco J Alcain. Sex-dependent co-occurrence of hypoxia and β-amyloid plaques in hippocampus and entorhinal cortex is reversed by long-term treatment with ubiquinol and ascorbic acid in the 3 × Tg-AD mouse model of Alzheimer's disease.
Molecular and cellular neurosciences.
2018 10; 92(?):67-81. doi:
10.1016/j.mcn.2018.06.005. [PMID: 29953929] - Chi-Hua Yen, Ying-Ju Chu, Bor-Jen Lee, Yi-Chin Lin, Ping-Ting Lin. Effect of liquid ubiquinol supplementation on glucose, lipids and antioxidant capacity in type 2 diabetes patients: a double-blind, randomised, placebo-controlled trial.
The British journal of nutrition.
2018 07; 120(1):57-63. doi:
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Biomeditsinskaia khimiia.
2018 Mar; 64(2):188-194. doi:
10.18097/pbmc20186402188. [PMID: 29723149] - Jun Mitsui, Ken Koguchi, Toshimitsu Momose, Miwako Takahashi, Takashi Matsukawa, Tsutomu Yasuda, Shin-Ichi Tokushige, Hiroyuki Ishiura, Jun Goto, Shigeaki Nakazaki, Tomoyoshi Kondo, Hidefumi Ito, Yorihiro Yamamoto, Shoji Tsuji. Three-Year Follow-Up of High-Dose Ubiquinol Supplementation in a Case of Familial Multiple System Atrophy with Compound Heterozygous COQ2 Mutations.
Cerebellum (London, England).
2017 06; 16(3):664-672. doi:
10.1007/s12311-017-0846-9. [PMID: 28150130] - Xiehuang Sheng, Chao Shan, Jianbiao Liu, Jintong Yang, Bin Sun, Dezhan Chen. Theoretical insights into the mechanism of ferroptosis suppression via inactivation of a lipid peroxide radical by liproxstatin-1.
Physical chemistry chemical physics : PCCP.
2017 May; 19(20):13153-13159. doi:
10.1039/c7cp00804j. [PMID: 28489094] - Alvaro Sarmiento, Javier Diaz-Castro, Mario Pulido-Moran, Jorge Moreno-Fernandez, Naroa Kajarabille, Ignacio Chirosa, Isabel M Guisado, Luis Javier Chirosa, Rafael Guisado, Julio J Ochoa. Short-term ubiquinol supplementation reduces oxidative stress associated with strenuous exercise in healthy adults: A randomized trial.
BioFactors (Oxford, England).
2016 Nov; 42(6):612-622. doi:
10.1002/biof.1297. [PMID: 27193497] - Alexandra Fischer, Simone Onur, Petra Niklowitz, Thomas Menke, Matthias Laudes, Frank Döring. Coenzyme Q10 redox state predicts the concentration of c-reactive protein in a large caucasian cohort.
BioFactors (Oxford, England).
2016 May; 42(3):268-76. doi:
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Critical care (London, England).
2015 Jul; 19(?):275. doi:
10.1186/s13054-015-0989-3. [PMID: 26130237] - Yvonne Y Clark, Loren E Wold, Laura A Szalacha, Donna O McCarthy. Ubiquinol reduces muscle wasting but not fatigue in tumor-bearing mice.
Biological research for nursing.
2015 May; 17(3):321-9. doi:
10.1177/1099800414543822. [PMID: 25230747] - Simone Onur, Petra Niklowitz, Gunnar Jacobs, Wolfgang Lieb, Thomas Menke, Frank Döring. Association between serum level of ubiquinol and NT-proBNP, a marker for chronic heart failure, in healthy elderly subjects.
BioFactors (Oxford, England).
2015 Jan; 41(1):35-43. doi:
10.1002/biof.1198. [PMID: 25728634] - Simone Onur, Petra Niklowitz, Gunnar Jacobs, Ute Nöthlings, Wolfgang Lieb, Thomas Menke, Frank Döring. Ubiquinol reduces gamma glutamyltransferase as a marker of oxidative stress in humans.
BMC research notes.
2014 Jul; 7(?):427. doi:
10.1186/1756-0500-7-427. [PMID: 24996614] - Paul Bennetts, Qiuhua Shen, Amanda R Thimmesch, Francisco J Diaz, Richard L Clancy, Janet D Pierce. Effects of ubiquinol with fluid resuscitation following haemorrhagic shock on rat lungs, diaphragm, heart and kidneys.
Experimental physiology.
2014 Jul; 99(7):1007-15. doi:
10.1113/expphysiol.2014.078600. [PMID: 24860150] - W Peerapanyasut, K Thamprasert, O Wongmekiat. Ubiquinol supplementation protects against renal ischemia and reperfusion injury in rats.
Free radical research.
2014 Feb; 48(2):180-9. doi:
10.3109/10715762.2013.858148. [PMID: 24151980] - Anna Gvozdjáková, Jarmila Kucharská, Daniela Ostatníková, Katarína Babinská, Dalibor Nakládal, Fred L Crane. Ubiquinol improves symptoms in children with autism.
Oxidative medicine and cellular longevity.
2014; 2014(?):798957. doi:
10.1155/2014/798957. [PMID: 24707344] - Jinfeng Qu, Li Ma, Junhua Zhang, Steffen Jockusch, Ilyas Washington. Dietary chlorophyll metabolites catalyze the photoreduction of plasma ubiquinone.
Photochemistry and photobiology.
2013 Mar; 89(2):310-3. doi:
10.1111/j.1751-1097.2012.01230.x. [PMID: 22928808] - Jacopo Lucchetti, Marianna Marino, Simonetta Papa, Massimo Tortarolo, Giovanna Guiso, Silvia Pozzi, Valentina Bonetto, Silvio Caccia, Ettore Beghi, Caterina Bendotti, Marco Gobbi. A mouse model of familial ALS has increased CNS levels of endogenous ubiquinol9/10 and does not benefit from exogenous administration of ubiquinol10.
PloS one.
2013; 8(7):e69540. doi:
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The Journal of urology.
2012 Aug; 188(2):526-31. doi:
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International braz j urol : official journal of the Brazilian Society of Urology.
2012 Mar; 38(2):230-4; discussion 234. doi:
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Atherosclerosis.
2011 Jul; 217(1):158-64. doi:
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Clinical and experimental nephrology.
2011 Feb; 15(1):30-3. doi:
10.1007/s10157-010-0350-8. [PMID: 20878200] - Constance Schmelzer, Petra Niklowitz, Jürgen G Okun, Dorothea Haas, Thomas Menke, Frank Döring. Ubiquinol-induced gene expression signatures are translated into altered parameters of erythropoiesis and reduced low density lipoprotein cholesterol levels in humans.
IUBMB life.
2011 Jan; 63(1):42-8. doi:
10.1002/iub.413. [PMID: 21280176] - Masayo Matsuzaki, Megumi Haruna, Yoko Hasumi, Kyouichi Sekine, Takashi Tanizaki, Etsuko Watanabe, Sachiyo Murashima. Ubiquinol-10 and ubiquinone-10 levels in umbilical cord blood of healthy foetuses and the venous blood of their mothers.
Free radical research.
2010 Nov; 44(11):1338-44. doi:
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Nature chemical biology.
2010 Jul; 6(7):515-7. doi:
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Biochimica et biophysica acta.
2010 Apr; 1797(4):443-50. doi:
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Journal of endocrinological investigation.
2009 Jul; 32(7):626-32. doi:
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Biomedical chromatography : BMC.
2008 Dec; 22(12):1403-8. doi:
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Journal of chromatographic science.
2008 Sep; 46(8):717-21. doi:
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International journal of toxicology.
2008 Mar; 27(2):189-215. doi:
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BioFactors (Oxford, England).
2008; 32(1-4):49-58. doi:
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BioFactors (Oxford, England).
2008; 32(1-4):119-28. doi:
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Journal of lipid research.
2007 Sep; 48(9):2079-85. doi:
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Acta cardiologica.
2007 Aug; 62(4):349-54. doi:
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Mitochondrion.
2007 Jun; 7 Suppl(?):S78-88. doi:
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Regulatory toxicology and pharmacology : RTP.
2007 Feb; 47(1):19-28. doi:
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Bioscience, biotechnology, and biochemistry.
2006 Jul; 70(7):1584-91. doi:
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Toxicology and applied pharmacology.
2005 Oct; 208(1):87-97. doi:
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Clinica chimica acta; international journal of clinical chemistry.
2004 Jun; 344(1-2):173-9. doi:
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Neurobiology of disease.
2004 Feb; 15(1):160-70. doi:
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Protoplasma.
2003 May; 221(1-2):109-16. doi:
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BioFactors (Oxford, England).
2003; 18(1-4):245-54. doi:
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Annals of clinical biochemistry.
2003 Jan; 40(Pt 1):100-1. doi:
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BioFactors (Oxford, England).
2003; 18(1-4):113-24. doi:
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Biochemical and biophysical research communications.
2002 Sep; 297(3):581-6. doi:
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Current problems in dermatology.
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