Cholesteryl formate (BioDeep_00000354332)
代谢物信息卡片
Cholesteryl formate
化学式: C28H46O2 (414.34976159999997)
中文名称: 甲酸胆固醇酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC=O)C)C
InChI: InChI=1S/C28H46O2/c1-19(2)7-6-8-20(3)24-11-12-25-23-10-9-21-17-22(30-18-29)13-15-27(21,4)26(23)14-16-28(24,25)5/h9,18-20,22-26H,6-8,10-17H2,1-5H3/t20-,22+,23+,24-,25+,26+,27+,28-/m1/s1
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:191866
- ChEBI: CHEBI:191868
- ChEBI: CHEBI:191869
- ChEBI: CHEBI:191864
- ChEBI: CHEBI:191863
- ChEBI: CHEBI:191861
- ChEBI: CHEBI:191862
- ChEBI: CHEBI:191865
- ChEBI: CHEBI:191867
- ChEBI: CHEBI:191860
- PubChem: 165217
- PubChem: 521143
- CAS: 4351-55-7
- PMhub: MS000162299
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hanjun Zhao, Lu Lu, Zheng Peng, Lin-Lei Chen, Xinjin Meng, Chuyuan Zhang, Jonathan Daniel Ip, Wan-Mui Chan, Allen Wing-Ho Chu, Kwok-Hung Chan, Dong-Yan Jin, Honglin Chen, Kwok-Yung Yuen, Kelvin Kai-Wang To. SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells.
Emerging microbes & infections.
2022 Dec; 11(1):277-283. doi:
10.1080/22221751.2021.2023329. [PMID: 34951565] - Hygor M R de Souza, Jéssica S Guedes, Rosana H C N Freitas, Luis G V Gelves, Harold H Fokoue, Carlos Mauricio R Sant'Anna, Eliezer J Barreiro, Lidia M Lima. Comparative chemical and biological hydrolytic stability of homologous esters and isosteres.
Journal of enzyme inhibition and medicinal chemistry.
2022 Dec; 37(1):718-727. doi:
10.1080/14756366.2022.2027933. [PMID: 35156494] - Siyao Zhang, Bijia Zhou, Like Zhou, Hui Zhou, Fengping Chen, Shuling Yang, Chaolan Chen, Xun Tuo. Alterations in the conformation and function of human serum albumin induced by the binding of methyl hydrogen phthalate.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2022 Oct; 278(?):121335. doi:
10.1016/j.saa.2022.121335. [PMID: 35526438] - Ruxianguli Aimuzi, Senyuan Huang, Kai Luo, Shengtao Ma, Xiaona Huo, Guiying Li, Ying Tian, Jun Zhang, Yingxin Yu. Levels and health risks of urinary phthalate metabolites and the association between phthalate exposure and unexplained recurrent spontaneous abortion: a large case-control study from China.
Environmental research.
2022 09; 212(Pt C):113393. doi:
10.1016/j.envres.2022.113393. [PMID: 35504341] - Lydia M Louis, Lesliam Quirós-Alcalá, Jordan R Kuiper, Gregory Diette, Nadia N Hansel, Meredith C McCormack, John D Meeker, Jessie P Buckley. Variability and predictors of urinary organophosphate ester concentrations among school-aged children.
Environmental research.
2022 Sep; 212(Pt A):113192. doi:
10.1016/j.envres.2022.113192. [PMID: 35346652] - Stephanie C Hammel, Shila Nordone, Sharon Zhang, Amelia M Lorenzo, Brian Eichner, M Anthony Moody, Lynn Harrington, Joyce Gandee, Liz Schmidt, Stephanie Smith, Heather M Stapleton, Kate Hoffman. Infants' diminished response to DTaP vaccine is associated with exposure to organophosphate esters.
The Science of the total environment.
2022 Sep; 837(?):155782. doi:
10.1016/j.scitotenv.2022.155782. [PMID: 35533854] - Bernhard H Monien, Klaus Abraham. Levels of 2,3-dihydroxypropyl mercapturic acid (DHPMA) in human urine do not reflect the exposure to 3-chloro-1,2-propanediol (3-MCPD) or glycidol.
Environmental research.
2022 08; 211(?):112977. doi:
10.1016/j.envres.2022.112977. [PMID: 35248561] - Yacong Bo, Yongjian Zhu. Organophosphate esters exposure in relation to glucose homeostasis and type 2 diabetes in adults: A national cross-sectional study from the national health and nutrition survey.
Chemosphere.
2022 Aug; 301(?):134669. doi:
10.1016/j.chemosphere.2022.134669. [PMID: 35460677] - Radhiahtul Raehan Mustafa, Rashidah Sukor, Siti Mariam Mohd Nor, Nazamid Saari. Methyl ester and aromatic ether modification of mitragynine for generation of mitragynine-specific polyclonal antibodies.
Journal of immunological methods.
2022 Aug; 507(?):113291. doi:
10.1016/j.jim.2022.113291. [PMID: 35640723] - Xiaoying Li, Lei Wang, Yu Wang, Yiming Yao, Peng Zhang, Hongzhi Zhao, Hongwen Sun. Occupational exposure to organophosphate esters in e-waste dismantling workers: Risk assessment and influencing factors screening.
Ecotoxicology and environmental safety.
2022 Jul; 240(?):113707. doi:
10.1016/j.ecoenv.2022.113707. [PMID: 35653973] - Zhaoqing Lyu, Kouji H Harada, Sungmin Kim, Tomoko Fujitani, Yang Cao, Toshiaki Hitomi, Yukiko Fujii, Younglim Kho, Kyungho Choi. Exposure to phthalate esters in Japanese females in Kyoto, Japan from 1993 to 2016: Temporal trends and associated health risks.
Environment international.
2022 07; 165(?):107288. doi:
10.1016/j.envint.2022.107288. [PMID: 35588674] - Elias Abedelnour, Stephanie Ognier, Mengxue Zhang, Laurent Schio, Olivier Venier, Janine Cossy, Michael Tatoulian. Plasma flow chemistry for direct N-acylation of amines by esters.
Chemical communications (Cambridge, England).
2022 Jun; 58(52):7281-7284. doi:
10.1039/d2cc01940j. [PMID: 35678143] - Yingxu Wu, Xiaojing Deng, Lan Ye, Wei Zhang, Hu Xu, Boyu Zhang. A TCF-Based Carbon Monoxide NIR-Probe without the Interference of BSA and Its Application in Living Cells.
Molecules (Basel, Switzerland).
2022 Jun; 27(13):. doi:
10.3390/molecules27134155. [PMID: 35807401] - Priyanka Matin, Umme Hanee, Muhammad Shaiful Alam, Jae Eon Jeong, Mohammed Mahbubul Matin, Md Rezaur Rahman, Shafi Mahmud, Mohammed Merae Alshahrani, Bonglee Kim. Novel Galactopyranoside Esters: Synthesis, Mechanism, In Vitro Antimicrobial Evaluation and Molecular Docking Studies.
Molecules (Basel, Switzerland).
2022 Jun; 27(13):. doi:
10.3390/molecules27134125. [PMID: 35807371] - Ruben Weckx, Chloë Goossens, Sarah Derde, Lies Pauwels, Sarah Vander Perre, Greet Van den Berghe, Lies Langouche. Efficacy and safety of ketone ester infusion to prevent muscle weakness in a mouse model of sepsis-induced critical illness.
Scientific reports.
2022 Jun; 12(1):10591. doi:
10.1038/s41598-022-14961-w. [PMID: 35732826] - Xiaojie Li, Liangxiong Xu, Zhencheng Lv, Fengming Li, Jinghua Xue, Yonghong Peng, Xiaoyi Wei, Ling Li. Antifungal Mechanism of MTE-1, a Novel Oligosaccharide Ester, against Ustilaginoidea virens.
Journal of agricultural and food chemistry.
2022 Jun; 70(24):7441-7446. doi:
10.1021/acs.jafc.2c02380. [PMID: 35671376] - Nicholas A Lentini, Xueting Huang, Megan A Schladetsch, Chia-Hung Christine Hsiao, David F Wiemer, Andrew J Wiemer. Efficiency of bis-amidate phosphonate prodrugs.
Bioorganic & medicinal chemistry letters.
2022 06; 66(?):128724. doi:
10.1016/j.bmcl.2022.128724. [PMID: 35405283] - Olga I Yarovaya, Dmitriy N Shcherbakov, Sophia S Borisevich, Anastasiya S Sokolova, Maxim A Gureev, Edward M Khamitov, Nadezda B Rudometova, Anastasiya V Zybkina, Ekaterina D Mordvinova, Anna V Zaykovskaya, Artem D Rogachev, Oleg V Pyankov, Rinat A Maksyutov, Nariman F Salakhutdinov. Borneol Ester Derivatives as Entry Inhibitors of a Wide Spectrum of SARS-CoV-2 Viruses.
Viruses.
2022 06; 14(6):. doi:
10.3390/v14061295. [PMID: 35746766] - Yin-Peng Bai, Cheng-Jie Yang, Nan Deng, Mi Zhang, Zhi-Jun Zhang, Lei Li, Yong Zhou, Xiong-Fei Luo, Chuan-Rui Xu, Bao-Qi Zhang, Yue Ma, Ying-Qian Liu. Design and synthesis of novel 7-ethyl-10-fluoro-20-O-(cinnamic acid ester)-camptothecin derivatives as potential high selectivity and low toxicity topoisomerase I inhibitors for hepatocellular carcinoma.
Biochemical pharmacology.
2022 06; 200(?):115049. doi:
10.1016/j.bcp.2022.115049. [PMID: 35469784] - Vijeta Rai, Sunil Venkanna Pogu, Rajat Bhatnagar, Pranish Bomzan, Ankita Dutta, Amitava Mandal, Mahendra Nath Roy, Anoop Kumar, Shilpi Ghosh. Biological evaluation of a natural steroid ester, Stigmasta-5(6), 22(23)-dien-3-beta-yl acetate isolated from the Himalayan herb Astilbe rivularis as potential antitumor agent.
Chemico-biological interactions.
2022 Jun; 360(?):109935. doi:
10.1016/j.cbi.2022.109935. [PMID: 35427567] - Meng Yu, Xiang Li, Bingqing Liu, Yaping Li, Ling Liu, Limei Wang, Lulu Song, Youjie Wang, Liqin Hu, Surong Mei. Organophosphate esters in children and adolescents in Liuzhou city, China: concentrations, exposure assessment, and predictors.
Environmental science and pollution research international.
2022 Jun; 29(26):39310-39322. doi:
10.1007/s11356-021-18334-0. [PMID: 35098472] - S Songül Yalçin, İzzet Erdal, Semra Çetinkaya, Berna Oğuz. Urinary levels of phthalate esters and heavy metals in adolescents with thyroid colloid cysts.
International journal of environmental health research.
2022 Jun; 32(6):1359-1372. doi:
10.1080/09603123.2021.1883554. [PMID: 33555204] - Tong Wu, Seyed A Rabi, William A Michaud, David Becerra, Sarah E Gilpin, Mari Mino-Kenudson, Harald C Ott. Protease inhibitor Camostat Mesyalte blocks wild type SARS-CoV-2 and D614G viral entry in human engineered miniature lungs.
Biomaterials.
2022 06; 285(?):121509. doi:
10.1016/j.biomaterials.2022.121509. [PMID: 35533440] - Hesham Shamshoum, Kyle D Medak, Greg L McKie, Margaret K Hahn, David C Wright. Fasting or the short-term consumption of a ketogenic diet protects against antipsychotic-induced hyperglycaemia in mice.
The Journal of physiology.
2022 06; 600(11):2713-2728. doi:
10.1113/jp282922. [PMID: 35507699] - Ajay Kumar, Sandeep Kaur, Sukhvinder Dhiman, Prithvi Pal Singh, Gaurav Bhatia, Sharad Thakur, Hardeep Singh Tuli, Upendra Sharma, Subodh Kumar, Abdulmajeed G Almutary, Abdullah M Alnuqaydan, Arif Hussain, Shafiul Haque, Kuldeep Dhama, Satwinderjeet Kaur. Targeting Akt/NF-κB/p53 Pathway and Apoptosis Inducing Potential of 1,2-Benzenedicarboxylic Acid, Bis (2-Methyl Propyl) Ester Isolated from Onosma bracteata Wall. against Human Osteosarcoma (MG-63) Cells.
Molecules (Basel, Switzerland).
2022 May; 27(11):. doi:
10.3390/molecules27113478. [PMID: 35684419] - Jiayin Zhang, Kwan-Kit Jason Chan, Wan Chan. Synergistic Interaction of Polycyclic Aromatic Hydrocarbons, Phthalate Esters, or Phenol on DNA Adduct Formation by Aristolochic Acid I: Insights into the Etiology of Balkan Endemic Nephropathy.
Chemical research in toxicology.
2022 05; 35(5):849-857. doi:
10.1021/acs.chemrestox.2c00026. [PMID: 35471859] - Ao Li, Lingyi Kang, Runjie Li, Sijing Wu, Ke Liu, Xinke Wang. Modeling di (2-ethylhexyl) Phthalate (DEHP) and Its Metabolism in a Body's Organs and Tissues through Different Intake Pathways into Human Body.
International journal of environmental research and public health.
2022 05; 19(9):. doi:
10.3390/ijerph19095742. [PMID: 35565138] - Weili Yang, Joseph M Braun, Ann M Vuong, Zana Percy, Yingying Xu, Changchun Xie, Ranjan Deka, Antonia M Calafat, Maria Ospina, Erika Werner, Kimberly Yolton, Kim M Cecil, Bruce P Lanphear, Aimin Chen. Maternal urinary OPE metabolite concentrations and blood pressure during pregnancy: The HOME study.
Environmental research.
2022 05; 207(?):112220. doi:
10.1016/j.envres.2021.112220. [PMID: 34656632] - Nicoline Løkken, Jesper H Storgaard, Karoline L Revsbech, Nicol C Voermans, Gerrit Van Hall, John Vissing, Mette C Ørngreen. No effect of oral ketone ester supplementation on exercise capacity in patients with McArdle disease and healthy controls: A randomized placebo-controlled cross-over study.
Journal of inherited metabolic disease.
2022 05; 45(3):502-516. doi:
10.1002/jimd.12484. [PMID: 35150142] - Ze Zhang, Pengwei Sun, Jiahui Zhao, Hongyuan Zhang, Xinyao Wang, Linshan Li, Lixia Xiong, Na Yang, Yuxin Li, Zhiguang Yuchi, Zhengming Li. Design, synthesis and biological activity of diamide compounds based on 3-substituent of the pyrazole ring†.
Pest management science.
2022 May; 78(5):2022-2033. doi:
10.1002/ps.6826. [PMID: 35122377] - Mohammed Mahbubul Matin, Monir Uzzaman, Shagir Ahammad Chowdhury, Md Mosharef Hossain Bhuiyan. In vitro antimicrobial, physicochemical, pharmacokinetics and molecular docking studies of benzoyl uridine esters against SARS-CoV-2 main protease.
Journal of biomolecular structure & dynamics.
2022 05; 40(8):3668-3680. doi:
10.1080/07391102.2020.1850358. [PMID: 33297848] - Sahabjada Siddiqui, Rumana Ahmad, Mohammed Alaidarous, Qamar Zia, Shabir Ahmad Mir, Bader Alshehri, Aditi Srivastava, Anchal Trivedi. Phytoconstituents from Moringa oleifera fruits target ACE2 and open spike glycoprotein to combat SARS-CoV-2: An integrative phytochemical and computational approach.
Journal of food biochemistry.
2022 05; 46(5):e14062. doi:
10.1111/jfbc.14062. [PMID: 35043973] - Chao Li, Yucheng Jin, Shen Xu, Huan He. A Pilot Study: Nails as a Non-invasive Biospecimen of Human Exposure to Phthalate Esters.
Bulletin of environmental contamination and toxicology.
2022 May; 108(5):963-968. doi:
10.1007/s00128-021-03424-z. [PMID: 35039885] - Alisa B Nelson, Lisa S Chow, Curtis C Hughey, Peter A Crawford, Patrycja Puchalska. Artifactual FA dimers mimic FAHFA signals in untargeted metabolomics pipelines.
Journal of lipid research.
2022 05; 63(5):100201. doi:
10.1016/j.jlr.2022.100201. [PMID: 35315332] - Yuri Kosinsky, Kirill Peskov, Donald R Stanski, Diana Wetmore, Joseph Vinetz. Semi-Mechanistic Pharmacokinetic-Pharmacodynamic Model of Camostat Mesylate-Predicted Efficacy against SARS-CoV-2 in COVID-19.
Microbiology spectrum.
2022 04; 10(2):e0216721. doi:
10.1128/spectrum.02167-21. [PMID: 35412356] - Daisuke Watase, Shuichi Setoguchi, Nami Nagata-Akaho, Shotaro Goto, Hirofumi Yamakawa, Ayano Yamada, Mitsuhisa Koga, Yoshiharu Karube, Kazuhisa Matsunaga, Jiro Takata. Cationic N,N-Dimethylglycine Ester Prodrug of 2R-α-Tocotrienol Promotes Intestinal Absorption via Efficient Self-Micellization with Intrinsic Bile Acid Anion.
Molecules (Basel, Switzerland).
2022 Apr; 27(9):. doi:
10.3390/molecules27092727. [PMID: 35566078] - Shiyang Qin, Guobin Xin, Juanna Wei, Genye He, Zengping Yuan, Hua Liu, Xu Zhang, Yuanfeng Wang, Wenfang Zhang, Jianghai Lu. Metabolic Profiles of 5F-MDMB-PICA in Human Urine, Serum and Hair Samples Using LC-Q Exactive HF-MS.
Journal of analytical toxicology.
2022 Apr; 46(4):408-420. doi:
10.1093/jat/bkab034. [PMID: 33860792] - Jogchum Plat, Lieve van Brakel, Ronald P Mensink. Plant stanol esters might optimise the immune response and improve the SARS-CoV-2/COVID-19 vaccine efficacy in overweight and obese subjects.
The British journal of nutrition.
2022 04; 127(7):1117-1118. doi:
10.1017/s0007114521001781. [PMID: 34044900] - Svetlana Baskal, Alexander Bollenbach, Catharina Mels, Ruan Kruger, Dimitrios Tsikas. Development, validation of a GC-MS method for the simultaneous measurement of amino acids, their PTM metabolites and AGEs in human urine, and application to the bi-ethnic ASOS study with special emphasis to lysine.
Amino acids.
2022 Apr; 54(4):615-641. doi:
10.1007/s00726-021-03031-6. [PMID: 34251524] - Jing-Fang Hsu, William Chih-Wei Chang, Wen-Ying Ho, Pao-Chi Liao. Exploration of long-term exposure markers for phthalate esters in human hair using liquid chromatography-tandem mass spectrometry.
Analytica chimica acta.
2022 Apr; 1200(?):339610. doi:
10.1016/j.aca.2022.339610. [PMID: 35256140] - Michael Kraemer, Sebastian Broecker, Theresa Kueting, Burkhard Madea, Alexandra Maas. Fatty acid esters as novel metabolites of γ-hydroxybutyric acid: A preliminary investigation.
Drug testing and analysis.
2022 Apr; 14(4):690-700. doi:
10.1002/dta.3213. [PMID: 34983082] - Wenrui Guo, Linsey M Porter, Thomas Wm Crozier, Matthew Coates, Akhilesh Jha, Mikel McKie, James A Nathan, Paul J Lehner, Edward Jd Greenwood, Frank McCaughan. Topical TMPRSS2 inhibition prevents SARS-CoV-2 infection in differentiated human airway cultures.
Life science alliance.
2022 04; 5(4):. doi:
10.26508/lsa.202101116. [PMID: 35110354] - Md R Amin, Farhana Yasmin, Sujan Dey, Shafi Mahmud, Md A Saleh, Talha B Emran, Imtiaj Hasan, Sultana Rajia, Yukiko Ogawa, Yuki Fujii, Masao Yamada, Yasuhiro Ozeki, Sarkar M A Kawsar. Methyl β-D-galactopyranoside esters as potential inhibitors for SARS-CoV-2 protease enzyme: synthesis, antimicrobial, PASS, molecular docking, molecular dynamics simulations and quantum computations.
Glycoconjugate journal.
2022 04; 39(2):261-290. doi:
10.1007/s10719-021-10039-3. [PMID: 35037163] - Lu Yang, Fei Li, Xinyu Cao, Xing Qiao, Changhu Xue, Jie Xu. Stability and bioavailability of protein matrix-encapsulated astaxanthin ester microcapsules.
Journal of the science of food and agriculture.
2022 Mar; 102(5):2144-2152. doi:
10.1002/jsfa.11556. [PMID: 34614199] - Yunlang Liu, Tingting Zhu, Zuoming Xie, Chen Deng, Xiujuan Qi, Rong Hu, Jinglin Wang, Jianyi Chen. Human Exposure to Chlorinated Organophosphate Ester Flame Retardants and Plasticizers in an Industrial Area of Shenzhen, China.
International journal of environmental research and public health.
2022 03; 19(5):. doi:
10.3390/ijerph19053126. [PMID: 35270815] - Xiao-Wei Zhang, Yao-Juan Chu, Yu-Hao Li, Xiu-Juan Li. Matrix compatibility of typical sol-gel solid-phase microextraction coatings in undiluted plasma and whole blood for the analysis of phthalic acid esters.
Analytical and bioanalytical chemistry.
2022 Mar; 414(7):2493-2503. doi:
10.1007/s00216-022-03890-2. [PMID: 35171297] - Zeyu Chen, Shi Qiu, Chichen Zhang, Yu Zhan, Liangren Liu, Yige Bao, Bo Chen, Yunjin Bai, Xiaonan Zheng, Yin Huang, Kun Jin, Ping Han, Qiang Wei. Association of urinary organophosphate esters level with sex steroid hormones levels in adult males: A nationwide study, NHANES 2013-2014.
Andrology.
2022 03; 10(3):567-575. doi:
10.1111/andr.13149. [PMID: 34964561] - Heidi Ledford. Hundreds of COVID trials could provide a deluge of new drugs.
Nature.
2022 03; 603(7899):25-27. doi:
10.1038/d41586-022-00562-0. [PMID: 35233098] - Muyao Xi, Giorgia La Barbera, Jane Nygaard Eriksen, August Pilegaard Prahm, Palle Bekker Jeppesen, Lars Ove Dragsted. Discovery of Urinary Biomarkers of Spinach Consumption Using Untargeted LC-MS Metabolomics in a Human Intervention Trial.
Molecular nutrition & food research.
2022 03; 66(6):e2100260. doi:
10.1002/mnfr.202100260. [PMID: 35072987] - Lan Mo, Guang-Lei Zhao, Xiao-Feng Li, Ning He, Xing-Long Xiao, Hai-Xia Xu, Yi-Gang Yu. Biocatalytical Acyl-Modification of Puerarin: Shape Gut Microbiota Profile and Improve Short Chain Fatty Acids Production in Rats.
Plant foods for human nutrition (Dordrecht, Netherlands).
2022 Mar; 77(1):44-50. doi:
10.1007/s11130-021-00936-1. [PMID: 34822099] - Liqin Hu, Meng Yu, Yaping Li, Ling Liu, Xiang Li, Lulu Song, Youjie Wang, Surong Mei. Association of exposure to organophosphate esters with increased blood pressure in children and adolescents.
Environmental pollution (Barking, Essex : 1987).
2022 Feb; 295(?):118685. doi:
10.1016/j.envpol.2021.118685. [PMID: 34923060] - Xianyu Wang, Elvis D Okoffo, Andrew Pw Banks, Yan Li, Kevin V Thomas, Cassandra Rauert, Lesa L Aylward, Jochen F Mueller. Phthalate esters in face masks and associated inhalation exposure risk.
Journal of hazardous materials.
2022 02; 423(Pt A):127001. doi:
10.1016/j.jhazmat.2021.127001. [PMID: 34479081] - Xinmiao Wang, Kefan Chen, Jin Qiu, Yuanyuan Hu, Fawen Yin, Xiaoyang Liu, Dayong Zhou. Gastrointestinal Distribution of Tyrosol Acyl Esters in Orally Infected Mice and Their Hydrolysis by Lactobacillus Species Isolated from the Feces of Mice.
Journal of agricultural and food chemistry.
2022 Feb; 70(4):1316-1326. doi:
10.1021/acs.jafc.1c07432. [PMID: 35068150] - Mingjing He, Kun Jin, Shi Qiu, Xinyang Liao, Xiaonan Zheng, Zeyu Chen, Jianzhong Ai, Lu Yang, Zhongyuan Jiang, Dan Hu, Qiang Wei. The associations between organophosphate esters and urinary incontinence in the general US population.
Environmental science and pollution research international.
2022 Feb; 29(7):10400-10407. doi:
10.1007/s11356-021-14153-5. [PMID: 34523086] - Madeleine M Mank, Leah F Reed, Camille J Walton, Madison L T Barup, Jennifer L Ather, Matthew E Poynter. Therapeutic ketosis decreases methacholine hyperresponsiveness in mouse models of inherent obese asthma.
American journal of physiology. Lung cellular and molecular physiology.
2022 02; 322(2):L243-L257. doi:
10.1152/ajplung.00309.2021. [PMID: 34936508] - Agneta A Runkel, Darja Mazej, Janja Snoj Tratnik, Žiga Tkalec, Tina Kosjek, Milena Horvat. Exposure of men and lactating women to environmental phenols, phthalates, and DINCH.
Chemosphere.
2022 Jan; 286(Pt 3):131858. doi:
10.1016/j.chemosphere.2021.131858. [PMID: 34399256] - Palayakotai R Raghavan. Metadichol®: A Novel Nanolipid Formulation That Inhibits SARS-CoV-2 and a Multitude of Pathological Viruses In Vitro.
BioMed research international.
2022; 2022(?):1558860. doi:
10.1155/2022/1558860. [PMID: 35039793] - K I Avgerinos, R J Mullins, J M Egan, D Kapogiannis. Ketone Ester Effects on Biomarkers of Brain Metabolism and Cognitive Performance in Cognitively Intact Adults ≥ 55 Years Old. A Study Protocol for a Double-Blinded Randomized Controlled Clinical Trial.
The journal of prevention of Alzheimer's disease.
2022 ; 9(1):54-66. doi:
10.14283/jpad.2022.3. [PMID: 35098974] - Ponsiree Jithavech, Piyapan Suwattananuruk, Hasriadi, Chawanphat Muangnoi, Worathat Thitikornpong, Pasarapa Towiwat, Opa Vajragupta, Pornchai Rojsitthisak. Physicochemical investigation of a novel curcumin diethyl γ-aminobutyrate, a carbamate ester prodrug of curcumin with enhanced anti-neuroinflammatory activity.
PloS one.
2022; 17(3):e0265689. doi:
10.1371/journal.pone.0265689. [PMID: 35303012] - Victoria G Klein, Adam G Bond, Conner Craigon, R Scott Lokey, Alessio Ciulli. Amide-to-Ester Substitution as a Strategy for Optimizing PROTAC Permeability and Cellular Activity.
Journal of medicinal chemistry.
2021 12; 64(24):18082-18101. doi:
10.1021/acs.jmedchem.1c01496. [PMID: 34881891] - Minmin Hou, Jianlong Fang, Yali Shi, Song Tang, Haoran Dong, Yuanyuan Liu, Fuchang Deng, John P Giesy, Krystal J Godri Pollitt, Yaqi Cai, Xiaoming Shi. Exposure to organophosphate esters in elderly people: Relationships of OPE body burdens with indoor air and dust concentrations and food consumption.
Environment international.
2021 12; 157(?):106803. doi:
10.1016/j.envint.2021.106803. [PMID: 34365320] - Laura Schioppa, Fanta Fall, Sergio Ortiz, Jacques H Poupaert, Joelle Quetin-Leclercq. A Validated HPLC-PDA-HRMS Method to Investigate the Biological Stability and Metabolism of Antiparasitic Triterpenic Esters.
Molecules (Basel, Switzerland).
2021 Nov; 26(23):. doi:
10.3390/molecules26237154. [PMID: 34885738] - Dapeng Zhang, Elena N Atochina-Vasserman, Devendra S Maurya, Matthew Liu, Qi Xiao, Juncheng Lu, George Lauri, Nathan Ona, Erin K Reagan, Houping Ni, Drew Weissman, Virgil Percec. Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers.
Journal of the American Chemical Society.
2021 11; 143(43):17975-17982. doi:
10.1021/jacs.1c09585. [PMID: 34672554] - Sadia Z Shah, Alan H Bryce. On the Road Back to Normalcy: Following Science Over Noise in SARS-CoV-2.
Mayo Clinic proceedings.
2021 11; 96(11):2736-2742. doi:
10.1016/j.mayocp.2021.09.011. [PMID: 34736604] - Yun Tao, Liqin Hu, Ling Liu, Meng Yu, Yaping Li, Xiang Li, Wenyu Liu, Dan Luo, Adrian Covaci, Wei Xia, Shunqing Xu, Yuanyuan Li, Surong Mei. Prenatal exposure to organophosphate esters and neonatal thyroid-stimulating hormone levels: A birth cohort study in Wuhan, China.
Environment international.
2021 11; 156(?):106640. doi:
10.1016/j.envint.2021.106640. [PMID: 34015666] - Matthew Mahoney, Vishnu C Damalanka, Michael A Tartell, Dong Hee Chung, André Luiz Lourenço, Dustin Pwee, Anne E Mayer Bridwell, Markus Hoffmann, Jorine Voss, Partha Karmakar, Nurit P Azouz, Andrea M Klingler, Paul W Rothlauf, Cassandra E Thompson, Melody Lee, Lidija Klampfer, Christina L Stallings, Marc E Rothenberg, Stefan Pöhlmann, Sean P J Whelan, Anthony J O'Donoghue, Charles S Craik, James W Janetka. A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells.
Proceedings of the National Academy of Sciences of the United States of America.
2021 10; 118(43):. doi:
10.1073/pnas.2108728118. [PMID: 34635581] - Fabio Arena, Anna Rita Daniela Coda, Valentina Meschini, Roberto Verzicco, Arcangelo Liso. Droplets generated from toilets during urination as a possible vehicle of carbapenem-resistant Klebsiella pneumoniae.
Antimicrobial resistance and infection control.
2021 10; 10(1):149. doi:
10.1186/s13756-021-01023-5. [PMID: 34670621] - Azita H Talasaz, Parham Sadeghipour, Maryam Aghakouchakzadeh, Isaac Dreyfus, Hessam Kakavand, Hamid Ariannejad, Aakriti Gupta, Mahesh V Madhavan, Benjamin W Van Tassell, David Jimenez, Manuel Monreal, Muthiah Vaduganathan, John Fanikos, Dave L Dixon, Gregory Piazza, Sahil A Parikh, Deepak L Bhatt, Gregory Y H Lip, Gregg W Stone, Harlan M Krumholz, Peter Libby, Samuel Z Goldhaber, Behnood Bikdeli. Investigating Lipid-Modulating Agents for Prevention or Treatment of COVID-19: JACC State-of-the-Art Review.
Journal of the American College of Cardiology.
2021 10; 78(16):1635-1654. doi:
10.1016/j.jacc.2021.08.021. [PMID: 34649702] - Ko Sato, Hideki Hayashi, Yoshitaka Shimotai, Mutsuo Yamaya, Seiji Hongo, Kazuyoshi Kawakami, Yoko Matsuzaki, Hidekazu Nishimura. TMPRSS2 Activates Hemagglutinin-Esterase Glycoprotein of Influenza C Virus.
Journal of virology.
2021 10; 95(21):e0129621. doi:
10.1128/jvi.01296-21. [PMID: 34406864] - Alex J B Kreutzberger, Anwesha Sanyal, Ravi Ojha, Jesse D Pyle, Olli Vapalahti, Giuseppe Balistreri, Tom Kirchhausen. Synergistic Block of SARS-CoV-2 Infection by Combined Drug Inhibition of the Host Entry Factors PIKfyve Kinase and TMPRSS2 Protease.
Journal of virology.
2021 10; 95(21):e0097521. doi:
10.1128/jvi.00975-21. [PMID: 34406858] - Patrice E Fort, Thekkelnaycke M Rajendiran, Tanu Soni, Jaeman Byun, Yang Shan, Helen C Looker, Robert G Nelson, Matthias Kretzler, George Michailidis, Jerome E Roger, Thomas W Gardner, Steven F Abcouwer, Subramaniam Pennathur, Farsad Afshinnia. Diminished retinal complex lipid synthesis and impaired fatty acid β-oxidation associated with human diabetic retinopathy.
JCI insight.
2021 10; 6(19):. doi:
10.1172/jci.insight.152109. [PMID: 34437304] - Ryota Hosomi, Anna Matsudo, Koki Sugimoto, Takaki Shimono, Seiji Kanda, Toshimasa Nishiyama, Munehiro Yoshida, Kenji Fukunaga. Dietary Eicosapentaenoic Acid and Docosahexaenoic Acid Ethyl Esters Influence the Gut Microbiota and Bacterial Metabolites in Rats.
Journal of oleo science.
2021 Oct; 70(10):1469-1480. doi:
10.5650/jos.ess21189. [PMID: 34497184] - Heather B Patisaul, Mamta Behl, Linda S Birnbaum, Arlene Blum, Miriam L Diamond, Seth Rojello Fernández, Helena T Hogberg, Carol F Kwiatkowski, Jamie D Page, Anna Soehl, Heather M Stapleton. Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers.
Environmental health perspectives.
2021 10; 129(10):105001. doi:
10.1289/ehp9285. [PMID: 34612677] - Yawen Yu, Liangxiao Wang, Junping Han, Aiping Wang, Liuxiang Chu, Xinran Xi, Ronglin Kan, Chunjie Sha, Kaoxiang Sun. Synthesis and Characterization of a Series of Temozolomide Esters and Its Anti-glioma Study.
Journal of pharmaceutical sciences.
2021 10; 110(10):3431-3438. doi:
10.1016/j.xphs.2021.06.025. [PMID: 34147518] - Lambert K Sørensen, Jørgen B Hasselstrøm, Jesper D Gunst, Ole S Søgaard, Mads Kjolby. Determination of camostat and its metabolites in human plasma - Preservation of samples and quantification by a validated UHPLC-MS/MS method.
Clinical biochemistry.
2021 Oct; 96(?):56-62. doi:
10.1016/j.clinbiochem.2021.07.007. [PMID: 34252447] - Yaxin Liu, Shuai Gong, Langjie Ye, Jianhua Li, Chunsheng Liu, Da Chen, Mingliang Fang, Robert J Letcher, Guanyong Su. Organophosphate (OP) diesters and a review of sources, chemical properties, environmental occurrence, adverse effects, and future directions.
Environment international.
2021 10; 155(?):106691. doi:
10.1016/j.envint.2021.106691. [PMID: 34146766] - Ewa Młodzińska-Michta, Weronika Korzeniowska. Gamma-oryzanol as an example of a complex of phytosterol esters and ferulic acid with broad biological activity.
Postepy biochemii.
2021 09; 67(3):205-211. doi:
10.18388/pb.2021_391. [PMID: 34894391] - Amand F Schmidt, Nicholas B Hunt, Maria Gordillo-Marañón, Pimphen Charoen, Fotios Drenos, Mika Kivimaki, Deborah A Lawlor, Claudia Giambartolomei, Olia Papacosta, Nishi Chaturvedi, Joshua C Bis, Christopher J O'Donnell, Goya Wannamethee, Andrew Wong, Jackie F Price, Alun D Hughes, Tom R Gaunt, Nora Franceschini, Dennis O Mook-Kanamori, Magdalena Zwierzyna, Reecha Sofat, Aroon D Hingorani, Chris Finan. Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease.
Nature communications.
2021 09; 12(1):5640. doi:
10.1038/s41467-021-25703-3. [PMID: 34561430] - Arun K Ghosh, Dana Shahabi, Monika Yadav, Satish Kovela, Brandon J Anson, Emma K Lendy, Connie Bonham, Devika Sirohi, Carlos A Brito-Sierra, Shin-Ichiro Hattori, Richard Kuhn, Hiroaki Mitsuya, Andrew D Mesecar. Chloropyridinyl Esters of Nonsteroidal Anti-Inflammatory Agents and Related Derivatives as Potent SARS-CoV-2 3CL Protease Inhibitors.
Molecules (Basel, Switzerland).
2021 Sep; 26(19):. doi:
10.3390/molecules26195782. [PMID: 34641337] - Xin Wang, Qingqing Zhu, Chunyang Liao, Guibin Jiang. Human internal exposure to organophosphate esters: A short review of urinary monitoring on the basis of biological metabolism research.
Journal of hazardous materials.
2021 09; 418(?):126279. doi:
10.1016/j.jhazmat.2021.126279. [PMID: 34329041] - Wei-Hsiang Chang, Samuel Herianto, Ching-Chang Lee, Hsin Hung, Hsiu-Ling Chen. The effects of phthalate ester exposure on human health: A review.
The Science of the total environment.
2021 Sep; 786(?):147371. doi:
10.1016/j.scitotenv.2021.147371. [PMID: 33965815] - Gaohui Sun, Yaqun Sui, Yang Zhou, Junlin Ya, Cai Yuan, Longguang Jiang, Mingdong Huang. Structural Basis of Covalent Inhibitory Mechanism of TMPRSS2-Related Serine Proteases by Camostat.
Journal of virology.
2021 09; 95(19):e0086121. doi:
10.1128/jvi.00861-21. [PMID: 34160253] - Junsaku Kitagawa, Hayato Arai, Hiroyuki Iida, Jiro Mukai, Kenji Furukawa, Seitaro Ohtsu, Susumu Nakade, Tomohiro Hikima, Miwa Haranaka, Naoto Uemura. A phase I study of high dose camostat mesylate in healthy adults provides a rationale to repurpose the TMPRSS2 inhibitor for the treatment of COVID-19.
Clinical and translational science.
2021 09; 14(5):1967-1976. doi:
10.1111/cts.13052. [PMID: 33982445] - J Fernández-Arribas, T Moreno, R Bartrolí, E Eljarrat. COVID-19 face masks: A new source of human and environmental exposure to organophosphate esters.
Environment international.
2021 09; 154(?):106654. doi:
10.1016/j.envint.2021.106654. [PMID: 34051653] - Guido Linari, Francesco Dondi, Sofia Segatore, Kateryna Vasylyeva, Nikolina Linta, Marco Pietra, Rodolfo O Leal, Federico Fracassi. Evaluation of 1,2-O-dilauryl-rac-glycero glutaric acid-(6'-methylresorufin) ester (DGGR) and 1,2-diglyceride lipase assays in dogs with naturally occurring hypercortisolism.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.
2021 Sep; 33(5):817-824. doi:
10.1177/10406387211021345. [PMID: 34078197] - Giehae Choi, Alexander P Keil, David B Richardson, Julie L Daniels, Kate Hoffman, Gro D Villanger, Amrit K Sakhi, Cathrine Thomsen, Ted Reichborn-Kjennerud, Heidi Aase, Stephanie M Engel. Pregnancy exposure to organophosphate esters and the risk of attention-deficit hyperactivity disorder in the Norwegian mother, father and child cohort study.
Environment international.
2021 09; 154(?):106549. doi:
10.1016/j.envint.2021.106549. [PMID: 33910116] - Hao-Hao Shi, Ying Guo, Li-Pin Chen, Cheng-Cheng Wang, Qing-Rong Huang, Chang-Hu Xue, Yu-Ming Wang, Tian-Tian Zhang. Docosahexaenoic Acid-Acylated Astaxanthin Esters Exhibit Superior Renal Protective Effect to Recombination of Astaxanthin with DHA via Alleviating Oxidative Stress Coupled with Apoptosis in Vancomycin-Treated Mice with Nephrotoxicity.
Marine drugs.
2021 Aug; 19(9):. doi:
10.3390/md19090499. [PMID: 34564161] - Yujie Wang, Ming Yang, Fushun Wang, Xueping Chen, Minghong Wu, Jing Ma. Organophosphate Esters in Indoor Environment and Metabolites in Human Urine Collected from a Shanghai University.
International journal of environmental research and public health.
2021 08; 18(17):. doi:
10.3390/ijerph18179212. [PMID: 34501802] - Kun Li, David K Meyerholz, Jennifer A Bartlett, Paul B McCray. The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19.
mBio.
2021 08; 12(4):e0097021. doi:
10.1128/mbio.00970-21. [PMID: 34340553] - Sarah Halford, Susan Wan, Ilaria Dragoni, Julie Silvester, Bobojon Nazarov, Daniel Anthony, Suzie Anthony, Emma Ladds, John Norrie, Kevin Dhaliwal. SPIKE-1: A Randomised Phase II/III trial in a community setting, assessing use of camostat in reducing the clinical progression of COVID-19 by blocking SARS-CoV-2 Spike protein-initiated membrane fusion.
Trials.
2021 Aug; 22(1):550. doi:
10.1186/s13063-021-05461-9. [PMID: 34412682] - Giehae Choi, Alexander P Keil, Gro D Villanger, David B Richardson, Julie L Daniels, Kate Hoffman, Amrit K Sakhi, Cathrine Thomsen, Amy H Herring, Samantha S M Drover, Rachel Nethery, Heidi Aase, Stephanie M Engel. Pregnancy exposure to common-detect organophosphate esters and phthalates and maternal thyroid function.
The Science of the total environment.
2021 Aug; 782(?):146709. doi:
10.1016/j.scitotenv.2021.146709. [PMID: 33839654] - Teruhiko Mizumoto, Yutaka Kakizoe, Terumasa Nakagawa, Yasunobu Iwata, Yoshikazu Miyasato, Kohei Uchimura, Masataka Adachi, Qinyuan Deng, Manabu Hayata, Jun Morinaga, Taku Miyoshi, Yuichiro Izumi, Takashige Kuwabara, Yoshiki Sakai, Kimio Tomita, Kenichiro Kitamura, Masashi Mukoyama. A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats.
Journal of pharmacological sciences.
2021 Aug; 146(4):192-199. doi:
10.1016/j.jphs.2021.04.003. [PMID: 34116732] - Qitong Xie, Qingxia Guan, Liangzhong Li, Xiongfei Pan, Cheuk-Lam Ho, Xiaotu Liu, Sen Hou, Da Chen. Exposure of children and mothers to organophosphate esters: Prediction by house dust and silicone wristbands.
Environmental pollution (Barking, Essex : 1987).
2021 Aug; 282(?):117011. doi:
10.1016/j.envpol.2021.117011. [PMID: 33823314] - Markus Hoffmann, Heike Hofmann-Winkler, Nadine Krüger, Amy Kempf, Inga Nehlmeier, Luise Graichen, Prerna Arora, Anzhalika Sidarovich, Anna-Sophie Moldenhauer, Martin S Winkler, Sebastian Schulz, Hans-Martin Jäck, Metodi V Stankov, Georg M N Behrens, Stefan Pöhlmann. SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination.
Cell reports.
2021 07; 36(3):109415. doi:
10.1016/j.celrep.2021.109415. [PMID: 34270919] - Justin J Miller, Ishaan T Shah, Jayda Hatten, Yasaman Barekatain, Elizabeth A Mueller, Ahmed M Moustafa, Rachel L Edwards, Cynthia S Dowd, Geoffrey C Hoops, R Jeremy Johnson, Paul J Planet, Florian L Muller, Joseph M Jez, Audrey R Odom John. Structure-guided microbial targeting of antistaphylococcal prodrugs.
eLife.
2021 07; 10(?):. doi:
10.7554/elife.66657. [PMID: 34279224] - Manatchanok Kongdin, Bancha Mahong, Sang-Kyu Lee, Su-Hyeon Shim, Jong-Seong Jeon, James R Ketudat Cairns. Action of Multiple Rice β-Glucosidases on Abscisic Acid Glucose Ester.
International journal of molecular sciences.
2021 Jul; 22(14):. doi:
10.3390/ijms22147593. [PMID: 34299210] - Anne Huppertsberg, Leonard Kaps, Zifu Zhong, Sascha Schmitt, Judith Stickdorn, Kim Deswarte, Francis Combes, Christian Czysch, Jana De Vrieze, Sabah Kasmi, Niklas Choteschovsky, Adrian Klefenz, Carolina Medina-Montano, Pia Winterwerber, Chaojian Chen, Matthias Bros, Stefan Lienenklaus, Niek N Sanders, Kaloian Koynov, Detlef Schuppan, Bart N Lambrecht, Sunil A David, Bruno G De Geest, Lutz Nuhn. Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-like Receptor 7/8 Agonistic Immune Modulators.
Journal of the American Chemical Society.
2021 07; 143(26):9872-9883. doi:
10.1021/jacs.1c03772. [PMID: 34166595] - Wanlin Guo, Jiayin Zhang, Zhihan Sun, William H Orem, Calin A Tatu, Niko S Radulović, Dragan Milovanović, Nikola M Pavlović, Wan Chan. Analysis of Polycyclic Aromatic Hydrocarbons and Phthalate Esters in Soil and Food Grains from the Balkan Peninsula: Implication on DNA Adduct Formation by Aristolochic Acid I and Balkan Endemic Nephropathy.
Environmental science & technology.
2021 07; 55(13):9024-9032. doi:
10.1021/acs.est.1c00648. [PMID: 34125507] - Emília Valente, Bernard Testa, Luís Constantino. Activation of benzoate model prodrugs by mycobacteria. Comparison with mammalian plasma and liver hydrolysis.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2021 Jul; 162(?):105831. doi:
10.1016/j.ejps.2021.105831. [PMID: 33839258]