2,4-Dibromo-1-(4-bromophenoxy)benzene (BioDeep_00000035350)

   

human metabolite


代谢物信息卡片


2,4-dibromo-1-(4-Bromophenoxy)benzene, 9ci

化学式: C12H7Br3O (403.80469519999997)
中文名称: 2,4,4-三溴联苯醚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: BrC1=CC=C(OC2=CC=C(Br)C=C2Br)C=C1
InChI: InChI=1S/C12H7Br3O/c13-8-1-4-10(5-2-8)16-12-6-3-9(14)7-11(12)15/h1-7H

描述信息

2,4-Dibromo-1-(4-bromophenoxy)benzene is classified as a Food Contaminant (code WG) in the DFC.
Classified as a Food Contaminant (code WG) in the DFC

同义名列表

14 个代谢物同义名

2,4-dibromo-1-(4-Bromophenoxy)benzene, 9ci; 2,4-Dibromo-1-(4-bromophenoxy)benzene; 2,4,4-Tribrominated diphenyl ether; 2,4,4-Tribromodiphenyl ether; 2,2,4-Tribromodiphenyl ether; 244-Tribromodiphenylether; Tribromodiphenyl ether 28; BDE No 28 solution; 2,4,4-TriBDE; PBDE-28; PBDE 28; BDE 28; BDE-28; BDE28



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Aqeel Ahmad, Iqra Shahzadi, Samavia Mubeen, Nasim Ahmad Yasin, Waheed Akram, Waheed Ullah Khan, Tingquan Wu. Karrikinolide alleviates BDE-28, heat and Cd stressors in Brassica alboglabra by correlating and modulating biochemical attributes, antioxidative machinery and osmoregulators. Ecotoxicology and environmental safety. 2021 Apr; 213(?):112047. doi: 10.1016/j.ecoenv.2021.112047. [PMID: 33601172]
  • Yijing Chen, Aiqin Zhang, Huixiang Li, Yu Peng, Xinyu Lou, Minghui Liu, Jicheng Hu, Chen Liu, Baokai Wei, Jun Jin. Concentrations and distributions of polybrominated diphenyl ethers (PBDEs) in surface soils and tree bark in Inner Mongolia, northern China, and the risks posed to humans. Chemosphere. 2020 May; 247(?):125950. doi: 10.1016/j.chemosphere.2020.125950. [PMID: 31978667]
  • Huang Huang, Andreas Sjodin, Yingtai Chen, Xin Ni, Shuangge Ma, Herbert Yu, Mary H Ward, Robert Udelsman, Jennifer Rusiecki, Yawei Zhang. Polybrominated Diphenyl Ethers, Polybrominated Biphenyls, and Risk of Papillary Thyroid Cancer: A Nested Case-Control Study. American journal of epidemiology. 2020 02; 189(2):120-132. doi: 10.1093/aje/kwz229. [PMID: 31742588]
  • Henry Matovu, Mika Sillanpää, Patrick Ssebugere. Polybrominated diphenyl ethers in mothers' breast milk and associated health risk to nursing infants in Uganda. The Science of the total environment. 2019 Nov; 692(?):1106-1115. doi: 10.1016/j.scitotenv.2019.07.335. [PMID: 31539942]
  • Yumei Huang, Muting Yan, Huayue Nie, Wenjing Wang, Jun Wang. Persistent halogenated organic pollutants in follicular fluid of women undergoing in vitro fertilization from China: Occurrence, congener profiles, and possible sources. Environmental pollution (Barking, Essex : 1987). 2019 Jan; 244(?):1-8. doi: 10.1016/j.envpol.2018.09.134. [PMID: 30317085]
  • Hongkai Zhu, Hongwen Sun, Yiming Yao, Zhiwei Gan, Yu Wang, Kurunthachalam Kannan. Legacy and alternative brominated flame retardants in outdoor dust and pine needles in mainland China: Spatial trends, dust-plant partitioning and human exposure. Environmental pollution (Barking, Essex : 1987). 2018 Dec; 243(Pt A):758-765. doi: 10.1016/j.envpol.2018.08.097. [PMID: 30228060]
  • Emily Parry, Ami R Zota, June-Soo Park, Tracey J Woodruff. Polybrominated diphenyl ethers (PBDEs) and hydroxylated PBDE metabolites (OH-PBDEs): A six-year temporal trend in Northern California pregnant women. Chemosphere. 2018 Mar; 195(?):777-783. doi: 10.1016/j.chemosphere.2017.12.065. [PMID: 29289024]
  • Jing-Xin Wang, Lian-Jun Bao, Pei Luo, Lei Shi, Charles S Wong, Eddy Y Zeng. Intake, distribution, and metabolism of decabromodiphenyl ether and its main metabolites in chickens and implications for human dietary exposure. Environmental pollution (Barking, Essex : 1987). 2017 Dec; 231(Pt 1):795-801. doi: 10.1016/j.envpol.2017.08.084. [PMID: 28865385]
  • Satori A Marchitti, Suzanne E Fenton, Pauline Mendola, John F Kenneke, Erin P Hines. Polybrominated Diphenyl Ethers in Human Milk and Serum from the U.S. EPA MAMA Study: Modeled Predictions of Infant Exposure and Considerations for Risk Assessment. Environmental health perspectives. 2017 04; 125(4):706-713. doi: 10.1289/ehp332. [PMID: 27405099]
  • Patricia López, Marc Tienstra, Arjen Lommen, Hans G J Mol. Validation of an automated screening method for persistent organic contaminants in fats and oils by GC×GC-ToFMS. Food chemistry. 2016 Nov; 211(?):645-53. doi: 10.1016/j.foodchem.2016.05.041. [PMID: 27283679]
  • Mihua Shao, Ping Tao, Man Wang, Hongliang Jia, Yi-Fan Li. Trophic magnification of polybrominated diphenyl ethers in the marine food web from coastal area of Bohai Bay, North China. Environmental pollution (Barking, Essex : 1987). 2016 Jun; 213(?):379-385. doi: 10.1016/j.envpol.2016.02.034. [PMID: 26942685]
  • Honglin Huang, Sen Wang, Jitao Lv, Xuehui Xu, Shuzhen Zhang. Influences of artificial root exudate components on the behaviors of BDE-28 and BDE-47 in soils: desorption, availability, and biodegradation. Environmental science and pollution research international. 2016 Apr; 23(8):7702-11. doi: 10.1007/s11356-015-6025-y. [PMID: 26743650]
  • Long Xu, Xia Huo, Yuling Zhang, Weiqiu Li, Jianqing Zhang, Xijin Xu. Polybrominated diphenyl ethers in human placenta associated with neonatal physiological development at a typical e-waste recycling area in China. Environmental pollution (Barking, Essex : 1987). 2015 Jan; 196(?):414-22. doi: 10.1016/j.envpol.2014.11.002. [PMID: 25468211]
  • Anna Brudzińska-Kosior, Grzegorz Kosior, Jana Klánová, Lenka Vaňková, Petr Kukučka, Mária Chropeňová, Aleksandra Samecka-Cymerman, Krzysztof Kolon, Lucyna Mróz, Alexander J Kempers. Polybrominated diphenyl ethers (PBDEs) in herbaceous Centaurium erythraea affected by various sources of environmental pollution. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. 2015; 50(13):1369-75. doi: 10.1080/10934529.2015.1064282. [PMID: 26259715]
  • Shirley Poon, Michael G Wade, Katarina Aleksa, Dorothea F K Rawn, Amanda Carnevale, Dean W Gaertner, Amy Sadler, François Breton, Gideon Koren, Sheila R Ernest, Claudia Lalancette, Bernard Robaire, Barbara F Hales, Cynthia G Goodyer. Hair as a biomarker of systemic exposure to polybrominated diphenyl ethers. Environmental science & technology. 2014 Dec; 48(24):14650-8. doi: 10.1021/es502789h. [PMID: 25387207]
  • Nerina B Lana, Paula Berton, Adrian Covaci, Néstor F Ciocco, Esteban Barrera-Oro, Adrián Atencio, Jorgelina C Altamirano. Fingerprint of persistent organic pollutants in tissues of Antarctic notothenioid fish. The Science of the total environment. 2014 Nov; 499(?):89-98. doi: 10.1016/j.scitotenv.2014.08.033. [PMID: 25173865]
  • Jing Zheng, Ke-Hui Chen, Xiao-Jun Luo, Xiao Yan, Chun-Tao He, Yun-Jiang Yu, Guo-Cheng Hu, Xiao-Wu Peng, Ming-Zhong Ren, Zhong-Yi Yang, Bi-Xian Mai. Polybrominated Diphenyl Ethers (PBDEs) in paired human hair and serum from e-waste recycling workers: source apportionment of hair PBDEs and relationship between hair and serum. Environmental science & technology. 2014; 48(1):791-6. doi: 10.1021/es4044402. [PMID: 24320081]
  • Xiaowei Wang, Beidou Xi, Shouliang Huo, Lin Deng, Hongwei Pan, Xunfeng Xia, Jingtian Zhang, Yuqing Ren, Hongliang Liu. Polybrominated diphenyl ethers occurrence in major inflowing rivers of Lake Chaohu (China): characteristics, potential sources and inputs to lake. Chemosphere. 2013 Nov; 93(8):1624-31. doi: 10.1016/j.chemosphere.2013.08.024. [PMID: 24025535]
  • Yaxian Zhao, Xianli Ruan, Yuanyuan Li, Minchan Yan, Zhanfen Qin. Polybrominated diphenyl ethers (PBDEs) in aborted human fetuses and placental transfer during the first trimester of pregnancy. Environmental science & technology. 2013 Jun; 47(11):5939-46. doi: 10.1021/es305349x. [PMID: 23621775]
  • Miao Yu, Jiyan Liu, Thanh Wang, Jianteng Sun, Runzeng Liu, Guibin Jiang. Metabolites of 2,4,4'-tribrominated diphenyl ether (BDE-28) in pumpkin after in vivo and in vitro exposure. Environmental science & technology. 2013; 47(23):13494-501. doi: 10.1021/es404144p. [PMID: 24191731]
  • K Jakobsson, J Fång, M Athanasiadou, A Rignell-Hydbom, A Bergman. Polybrominated diphenyl ethers in maternal serum, umbilical cord serum, colostrum and mature breast milk. Insights from a pilot study and the literature. Environment international. 2012 Oct; 47(?):121-30. doi: 10.1016/j.envint.2012.05.006. [PMID: 22819984]
  • Paula I Johnson, Larisa Altshul, Daniel W Cramer, Stacey A Missmer, Russ Hauser, John D Meeker. Serum and follicular fluid concentrations of polybrominated diphenyl ethers and in-vitro fertilization outcome. Environment international. 2012 Sep; 45(?):9-14. doi: 10.1016/j.envint.2012.04.004. [PMID: 22572111]
  • Shengtao Ma, Zhiqiang Yu, Xiaolan Zhang, Guofa Ren, Ping'an Peng, Guoying Sheng, Jiamo Fu. Levels and congener profiles of polybrominated diphenyl ethers (PBDEs) in breast milk from Shanghai: implication for exposure route of higher brominated BDEs. Environment international. 2012 Jul; 42(?):72-7. doi: 10.1016/j.envint.2011.04.006. [PMID: 21550663]
  • Kyung Ho Kim, Diptiman D Bose, Atefeh Ghogha, Joyce Riehl, Rui Zhang, Christopher D Barnhart, Pamela J Lein, Isaac N Pessah. Para- and ortho-substitutions are key determinants of polybrominated diphenyl ether activity toward ryanodine receptors and neurotoxicity. Environmental health perspectives. 2011 Apr; 119(4):519-26. doi: 10.1289/ehp.1002728. [PMID: 21106467]
  • Jenny Rattfelt Nyholm, Anna Norman, Leif Norrgren, Peter Haglund, Patrik L Andersson. Maternal transfer of brominated flame retardants in zebrafish (Danio rerio). Chemosphere. 2008 Sep; 73(2):203-8. doi: 10.1016/j.chemosphere.2008.04.033. [PMID: 18514256]
  • Said Kinani, Stéphane Bouchonnet, Janine Abjean, Christian Campargue. Determination of polybromodiphenyl ethers (PBDEs) in milk cream by gas chromatography-mass spectrometry. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2008 Aug; 25(8):1007-14. doi: 10.1080/02652030701881843. [PMID: 18608499]
  • Katharina Maria Main, Hannu Kiviranta, Helena Eeva Virtanen, Erno Sundqvist, Jouni Tapio Tuomisto, Jouko Tuomisto, Terttu Vartiainen, Niels Erik Skakkebaek, Jorma Toppari. Flame retardants in placenta and breast milk and cryptorchidism in newborn boys. Environmental health perspectives. 2007 Oct; 115(10):1519-26. doi: 10.1289/ehp.9924. [PMID: 17938745]
  • Timo Hamers, Jorke H Kamstra, Edwin Sonneveld, Albertinka J Murk, Monique H A Kester, Patrik L Andersson, Juliette Legler, Abraham Brouwer. In vitro profiling of the endocrine-disrupting potency of brominated flame retardants. Toxicological sciences : an official journal of the Society of Toxicology. 2006 Jul; 92(1):157-73. doi: 10.1093/toxsci/kfj187. [PMID: 16601080]
  • Jae-Won Choi, T Susumu Fujimaki, Kimiyoshi Kitamura, Shunji Hashimoto, Hiroyasu Ito, Noriyuki Suzuki, Shin-ichi Sakai, Masatoshi Morita. Polybrominated dibenzo-p-dioxins, dibenzofurans, and diphenyl ethers in Japanese human adipose tissue. Environmental science & technology. 2003 Mar; 37(5):817-21. doi: 10.1021/es0258780. [PMID: 12666907]
  • Cathrine Thomsen, Elsa Lundanes, Georg Becher. Brominated flame retardants in archived serum samples from Norway: a study on temporal trends and the role of age. Environmental science & technology. 2002 Apr; 36(7):1414-8. doi: 10.1021/es0102282. [PMID: 11999045]
  • C Thomsen, E Lundanes, G Becher. Brominated flame retardants in plasma samples from three different occupational groups in Norway. Journal of environmental monitoring : JEM. 2001 Aug; 3(4):366-70. doi: 10.1039/b104304h. [PMID: 11523435]