Thiacremonone (BioDeep_00000034967)

   

human metabolite natural product


代谢物信息卡片


2,4-dihydroxy-2,5-dimethyl-2,3-dihydrothiophen-3-one

化学式: C6H8O3S (160.0194138)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(C(=O)C(S1)(C)O)O
InChI: InChI=1S/C6H8O3S/c1-3-4(7)5(8)6(2,9)10-3/h7,9H,1-2H3

描述信息

Thiacremonone is formed in the Maillard reaction of HHZ66-M and 4-Hydroxy-2,5-dimethyl-3(2H)-furanone FWS46-CFormed in the Maillard reaction of HHZ66-M and 4-Hydroxy-2,5-dimethyl-3(2H)-furanone FWS46-C

同义名列表

4 个代谢物同义名

2,4-dihydroxy-2,5-dimethyl-2,3-dihydrothiophen-3-one; 2,4-Dihydroxy-2,5-dimethyl-3(2H)-thiophenone, 9ci; 2,4-dihydroxy-2,5-dimethylthiophen-3-one; Thiacremonone



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hyung-Mun Yun, Peng Jin, Kyung-Ran Park, JaeRyun Hwang, Heon-Sang Jeong, Eun-Cheol Kim, Jea-Kyung Jung, Ki-Wan Oh, Bang Yeon Hwang, Sang Bae Han, Jin Tae Hong. Thiacremonone Potentiates Anti-Oxidant Effects to Improve Memory Dysfunction in an APP/PS1 Transgenic Mice Model. Molecular neurobiology. 2016 May; 53(4):2409-20. doi: 10.1007/s12035-015-9208-0. [PMID: 26008621]
  • Miran Jo, Hyung-Mun Yun, Kyung-Ran Park, Mi Hee Park, Dong Hun Lee, Seung Hee Cho, Hwan-Soo Yoo, Yong-Moon Lee, Heon Sang Jeong, Youngsoo Kim, Jae Kyung Jung, Bang Yeon Hwang, Mi Kyeong Lee, Nam Doo Kim, Sang Bae Han, Jin Tae Hong. Anti-cancer effect of thiacremonone through down regulation of peroxiredoxin 6. PloS one. 2014; 9(3):e91508. doi: 10.1371/journal.pone.0091508. [PMID: 24618722]
  • Eun Jin Kim, Dong Hun Lee, Hee Jong Kim, So Jung Lee, Jung Ok Ban, Min Chul Cho, Heon Sang Jeong, Young Yang, Jin Tae Hong, Do Young Yoon. Thiacremonone, a sulfur compound isolated from garlic, attenuates lipid accumulation partially mediated via AMPK activation in 3T3-L1 adipocytes. The Journal of nutritional biochemistry. 2012 Dec; 23(12):1552-8. doi: 10.1016/j.jnutbio.2011.10.008. [PMID: 22405697]
  • Jung Ok Ban, Dong Hun Lee, Eun Jin Kim, Jeong Woo Kang, Man Sub Kim, Min Chul Cho, Heon Sang Jeong, Jong Wan Kim, Young Yang, Jin Tae Hong, Do Young Yoon. Antiobesity effects of a sulfur compound thiacremonone mediated via down-regulation of serum triglyceride and glucose levels and lipid accumulation in the liver of db/db mice. Phytotherapy research : PTR. 2012 Sep; 26(9):1265-71. doi: 10.1002/ptr.3729. [PMID: 22228551]
  • Jung Ok Ban, Ju Hoon Oh, Tae Myoung Kim, Dae Joong Kim, Heon-Sang Jeong, Sang Bae Han, Jin Tae Hong. Anti-inflammatory and arthritic effects of thiacremonone, a novel sulfur compound isolated from garlic via inhibition of NF-kappaB. Arthritis research & therapy. 2009; 11(5):R145. doi: 10.1186/ar2819. [PMID: 19788760]
  • Jung Ok Ban, Dong Yeon Yuk, Koan Sik Woo, Tae Myoung Kim, Ung Soo Lee, Heon-Sang Jeong, Dae Joong Kim, Yeun Bok Chung, Bang Yeon Hwang, Ki Wan Oh, Jin Tae Hong. Inhibition of cell growth and induction of apoptosis via inactivation of NF-kappaB by a sulfurcompound isolated from garlic in human colon cancer cells. Journal of pharmacological sciences. 2007 Aug; 104(4):374-83. doi: 10.1254/jphs.fp0070789. [PMID: 17721042]