Phytantriol (BioDeep_00000344718)
代谢物信息卡片
Phytantriol
化学式: C20H42O3 (330.3133782)
中文名称: 植烷三醇 (异构体混合物)
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)CCCC(C)CCCC(C)CCCC(C)(C(CO)O)O
InChI: InChI=1S/C20H42O3/c1-16(2)9-6-10-17(3)11-7-12-18(4)13-8-14-20(5,23)19(22)15-21/h16-19,21-23H,6-15H2,1-5H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Haitao Yu, Brendan Dyett, Nigel Kirby, Xudong Cai, Mohamad El Mohamad, Steven Bozinovski, Calum J Drummond, Jiali Zhai. pH-Dependent Lyotropic Liquid Crystalline Mesophase and Ionization Behavior of Phytantriol-Based Ionizable Lipid Nanoparticles.
Small (Weinheim an der Bergstrasse, Germany).
2024 May; 20(20):e2309200. doi:
10.1002/smll.202309200. [PMID: 38295089] - Mohamad El Mohamad, Qi Han, Andrew J Clulow, Cheng Cao, Aneeqa Safdar, Martina Stenzel, Calum J Drummond, Tamar L Greaves, Jiali Zhai. Regulating the structural polymorphism and protein corona composition of phytantriol-based lipid nanoparticles using choline ionic liquids.
Journal of colloid and interface science.
2024 Mar; 657(?):841-852. doi:
10.1016/j.jcis.2023.12.005. [PMID: 38091907] - Saffron J Bryant, Aaron Elbourne, Tamar L Greaves, Gary Bryant. Phytantriol phase behaviour in choline chloride urea and water mixtures.
Journal of materials chemistry. B.
2023 07; 11(29):6868-6880. doi:
10.1039/d3tb00554b. [PMID: 37403522] - Haitao Yu, Brendan P Dyett, Jiali Zhai, Jamie B Strachan, Calum J Drummond, Charlotte E Conn. Formation of particulate lipid lyotropic liquid crystalline nanocarriers using a microfluidic platform.
Journal of colloid and interface science.
2023 Mar; 634(?):279-289. doi:
10.1016/j.jcis.2022.12.028. [PMID: 36542965] - Khaled M Hosny, Waleed Y Rizg, Eman Alfayez, Samar S Elgebaly, Abdulmohsin J Alamoudi, Raed I Felimban, Hossam H Tayeb, Rayan Y Mushtaq, Awaji Y Safhi, Majed Alharbi, Alshaimaa M Almehmady. Preparation and optimization of aloe ferox gel loaded with Finasteride-Oregano oil nanocubosomes for treatment of alopecia.
Drug delivery.
2022 Dec; 29(1):284-293. doi:
10.1080/10717544.2022.2026534. [PMID: 35019794] - Xiaohan Sun, Joanne D Du, Adrian Hawley, Angel Tan, Ben J Boyd. Magnetically-stimulated transformations in the nanostructure of PEGylated phytantriol-based nanoparticles for on-demand drug release.
Colloids and surfaces. B, Biointerfaces.
2021 Nov; 207(?):112005. doi:
10.1016/j.colsurfb.2021.112005. [PMID: 34339967] - Jakub Jagielski, Łucja Przysiecka, Dorota Flak, Magdalena Diak, Zuzanna Pietralik-Molińska, Maciej Kozak, Stefan Jurga, Grzegorz Nowaczyk. Comprehensive and comparative studies on nanocytotoxicity of glyceryl monooleate- and phytantriol-based lipid liquid crystalline nanoparticles.
Journal of nanobiotechnology.
2021 Jun; 19(1):168. doi:
10.1186/s12951-021-00913-5. [PMID: 34082768] - Elżbieta Jabłonowska, Dorota Matyszewska, Ewa Nazaruk, Marlena Godlewska, Damian Gaweł, Renata Bilewicz. Lipid membranes exposed to dispersions of phytantriol and monoolein cubosomes: Langmuir monolayer and HeLa cell membrane studies.
Biochimica et biophysica acta. General subjects.
2021 01; 1865(1):129738. doi:
10.1016/j.bbagen.2020.129738. [PMID: 32956751] - Julia Alvarez-Malmagro, Elżbieta Jablonowska, Ewa Nazaruk, Piotr Szwedziak, Renata Bilewicz. How do lipid nanocarriers - Cubosomes affect electrochemical properties of DMPC bilayers deposited on gold (111) electrodes?.
Bioelectrochemistry (Amsterdam, Netherlands).
2020 Aug; 134(?):107516. doi:
10.1016/j.bioelechem.2020.107516. [PMID: 32222670] - Marco Mendozza, Arianna Balestri, Costanza Montis, Debora Berti. Controlling the Kinetics of an Enzymatic Reaction through Enzyme or Substrate Confinement into Lipid Mesophases with Tunable Structural Parameters.
International journal of molecular sciences.
2020 Jul; 21(14):. doi:
10.3390/ijms21145116. [PMID: 32698376] - Letícia Rodrigues, Fabian Schneider, Xiaohan Zhang, Elin Larsson, Lindon W K Moodie, Hendrik Dietz, Christine M Papadakis, Gerhard Winter, Richard Lundmark, Madlen Hubert. Cellular uptake of self-assembled phytantriol-based hexosomes is independent of major endocytic machineries.
Journal of colloid and interface science.
2019 Oct; 553(?):820-833. doi:
10.1016/j.jcis.2019.06.045. [PMID: 31284226] - Larissa A Maiorova, Svetlana I Erokhina, Michela Pisani, Gianni Barucca, Massimo Marcaccio, Oscar I Koifman, Denis S Salnikov, Olga A Gromova, Paola Astolfi, Valentina Ricci, Victor Erokhin. Encapsulation of vitamin B12 into nanoengineered capsules and soft matter nanosystems for targeted delivery.
Colloids and surfaces. B, Biointerfaces.
2019 Oct; 182(?):110366. doi:
10.1016/j.colsurfb.2019.110366. [PMID: 31351273] - Xiao Liang, Yulin Chen, Li Wu, Abi Maharjan, Balmukunda Regmi, Jiwen Zhang, Shuangying Gui. In situ hexagonal liquid crystal for intra-articular delivery of sinomenine hydrochloride.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2019 Sep; 117(?):108993. doi:
10.1016/j.biopha.2019.108993. [PMID: 31228805] - Angel Tan, Yuen Yi Lam, Olivier Pacot, Adrian Hawley, Ben J Boyd. Probing cell-nanoparticle (cubosome) interactions at the endothelial interface: do tissue dimension and flow matter?.
Biomaterials science.
2019 Aug; 7(8):3460-3470. doi:
10.1039/c9bm00243j. [PMID: 31268062] - Huang Jie, Liu Liu, Gui Shuangying, Wang Xingqi, Hu Rongfeng, Zhang Yong, Tian Chunling, Xia Mengqiu, Chu Xiaoqin. A Novel Phytantriol-Based In Situ Liquid Crystal Gel for Vaginal Delivery.
AAPS PharmSciTech.
2019 May; 20(5):185. doi:
10.1208/s12249-019-1393-0. [PMID: 31062112] - Linda Hong, Yao-Da Dong, Ben J Boyd. Preparation of Nanostructured Lipid Drug Delivery Particles Using Microfluidic Mixing.
Pharmaceutical nanotechnology.
2019; 7(6):484-495. doi:
10.2174/2211738507666191004123545. [PMID: 31584384] - Amin Sadeghpour, Michael Rappolt, Shravasti Misra, Chandrashekhar V Kulkarni. Bile Salts Caught in the Act: From Emulsification to Nanostructural Reorganization of Lipid Self-Assemblies.
Langmuir : the ACS journal of surfaces and colloids.
2018 11; 34(45):13626-13637. doi:
10.1021/acs.langmuir.8b02343. [PMID: 30347980] - Letícia Rodrigues, Konstantinos N Raftopoulos, Signe Tandrup Schmidt, Fabian Schneider, Hendrik Dietz, Thomas Rades, Henrik Franzyk, Anders Elm Pedersen, Christine M Papadakis, Dennis Christensen, Gerhard Winter, Camilla Foged, Madlen Hubert. Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein.
Journal of controlled release : official journal of the Controlled Release Society.
2018 09; 285(?):12-22. doi:
10.1016/j.jconrel.2018.06.028. [PMID: 29964134] - Sanyog Jain, Pooja Yadav, Rajan Swami, Nitin Kumar Swarnakar, Varun Kushwah, Sameer S Katiyar. Lyotropic Liquid Crystalline Nanoparticles of Amphotericin B: Implication of Phytantriol and Glyceryl Monooleate on Bioavailability Enhancement.
AAPS PharmSciTech.
2018 May; 19(4):1699-1711. doi:
10.1208/s12249-018-0986-3. [PMID: 29532426] - Nhiem Tran, Xavier Mulet, Adrian M Hawley, Celesta Fong, Jiali Zhai, Tu C Le, Julian Ratcliffe, Calum J Drummond. Manipulating the Ordered Nanostructure of Self-Assembled Monoolein and Phytantriol Nanoparticles with Unsaturated Fatty Acids.
Langmuir : the ACS journal of surfaces and colloids.
2018 02; 34(8):2764-2773. doi:
10.1021/acs.langmuir.7b03541. [PMID: 29381863] - Joanne D Du, Linda Hong, Angel Tan, Ben J Boyd. Naphthalocyanine as a New Photothermal Actuator for Lipid-Based Drug Delivery Systems.
The journal of physical chemistry. B.
2018 02; 122(5):1766-1770. doi:
10.1021/acs.jpcb.7b12234. [PMID: 29316389] - Sanyog Jain, B Heeralal, Rajan Swami, Nitin K Swarnakar, Varun Kushwah. Improved Oral Bioavailability, Therapeutic Efficacy, and Reduced Toxicity of Tamoxifen-Loaded Liquid Crystalline Nanoparticles.
AAPS PharmSciTech.
2018 Jan; 19(1):460-469. doi:
10.1208/s12249-017-0851-9. [PMID: 28785860] - Xiao-Qin Chu, Jie Huang, Zheng-Guang Li, Qian Li, Jiao-Jiao Cao, Jian-Qin Jiang, Shuang-Ying Gui. On the Structure and Transdermal Profile of Liquid Crystals Based on Phytantriol.
Current drug delivery.
2018; 15(10):1439-1448. doi:
10.2174/1567201815666180910142516. [PMID: 30198435] - Qingtao Liu, Jinming Hu, Michael R Whittaker, Thomas P Davis, Ben J Boyd. Nitric oxide-sensing actuators for modulating structure in lipid-based liquid crystalline drug delivery systems.
Journal of colloid and interface science.
2017 Dec; 508(?):517-524. doi:
10.1016/j.jcis.2017.08.079. [PMID: 28866460] - Abdul Muheem, Faiyaz Shakeel, Musarrat Husain Warsi, Gaurav Kumar Jain, Farhan Jalees Ahmad. A Combinatorial Statistical Design Approach to Optimize the Nanostructured Cubosomal Carrier System for Oral Delivery of Ubidecarenone for Management of Doxorubicin-Induced Cardiotoxicity: In Vitro-In Vivo Investigations.
Journal of pharmaceutical sciences.
2017 10; 106(10):3050-3065. doi:
10.1016/j.xphs.2017.05.026. [PMID: 28552692] - Xuan Shi, Tingting Peng, Ying Huang, Liling Mei, Yukun Gu, Jiayuan Huang, Ke Han, Ge Li, Chunli Hu, Xin Pan, Chuanbin Wu. Comparative studies on glycerol monooleate- and phytantriol-based cubosomes containing oridonin in vitro and in vivo.
Pharmaceutical development and technology.
2017 May; 22(3):322-329. doi:
10.3109/10837450.2015.1121496. [PMID: 26670780] - Letícia Rodrigues, Konstantinos Kyriakos, Fabian Schneider, Hendrik Dietz, Gerhard Winter, Christine M Papadakis, Madlen Hubert. Characterization of Lipid-Based Hexosomes as Versatile Vaccine Carriers.
Molecular pharmaceutics.
2016 11; 13(11):3945-3954. doi:
10.1021/acs.molpharmaceut.6b00716. [PMID: 27607892] - F S Poletto, F S Lima, D Lundberg, T Nylander, W Loh. Tailoring the internal structure of liquid crystalline nanoparticles responsive to fungal lipases: A potential platform for sustained drug release.
Colloids and surfaces. B, Biointerfaces.
2016 Nov; 147(?):210-216. doi:
10.1016/j.colsurfb.2016.08.003. [PMID: 27518452] - Mohammad Younus, Richard N Prentice, Andrew N Clarkson, Ben J Boyd, Shakila B Rizwan. Incorporation of an Endogenous Neuromodulatory Lipid, Oleoylethanolamide, into Cubosomes: Nanostructural Characterization.
Langmuir : the ACS journal of surfaces and colloids.
2016 09; 32(35):8942-50. doi:
10.1021/acs.langmuir.6b02395. [PMID: 27524261] - Anna C Pham, Linda Hong, Oliver Montagnat, Cameron J Nowell, Tri-Hung Nguyen, Ben J Boyd. In Vivo Formation of Cubic Phase in Situ after Oral Administration of Cubic Phase Precursor Formulation Provides Long Duration Gastric Retention and Absorption for Poorly Water-Soluble Drugs.
Molecular pharmaceutics.
2016 Jan; 13(1):280-6. doi:
10.1021/acs.molpharmaceut.5b00784. [PMID: 26567591] - Anna C Pham, Tri-Hung Nguyen, Cameron J Nowell, Bim Graham, Ben J Boyd. Examining the gastrointestinal transit of lipid-based liquid crystalline systems using whole-animal imaging.
Drug delivery and translational research.
2015 Dec; 5(6):566-74. doi:
10.1007/s13346-015-0253-z. [PMID: 26328930] - Nicole B Bisset, Ben J Boyd, Yao-Da Dong. Tailoring liquid crystalline lipid nanomaterials for controlled release of macromolecules.
International journal of pharmaceutics.
2015 Nov; 495(1):241-248. doi:
10.1016/j.ijpharm.2015.08.072. [PMID: 26319637] - Jiali Zhai, Tracey M Hinton, Lynne J Waddington, Celesta Fong, Nhiem Tran, Xavier Mulet, Calum J Drummond, Benjamin W Muir. Lipid-PEG conjugates sterically stabilize and reduce the toxicity of phytantriol-based lyotropic liquid crystalline nanoparticles.
Langmuir : the ACS journal of surfaces and colloids.
2015 Oct; 31(39):10871-80. doi:
10.1021/acs.langmuir.5b02797. [PMID: 26362479] - Do-Hoon Kim, Sora Lim, Jongwon Shim, Ji Eun Song, Jong Soo Chang, Kyeong Sik Jin, Eun Chul Cho. A Simple Evaporation Method for Large-Scale Production of Liquid Crystalline Lipid Nanoparticles with Various Internal Structures.
ACS applied materials & interfaces.
2015 Sep; 7(36):20438-46. doi:
10.1021/acsami.5b06413. [PMID: 26305487] - Adam M Squires, Samina Akbar, Marissa E Tousley, Yekaterina Rokhlenko, Jonathan P Singer, Chinedum O Osuji. Experimental Evidence for Proposed Transformation Pathway from the Inverse Hexagonal to Inverse Diamond Cubic Phase from Oriented Lipid Samples.
Langmuir : the ACS journal of surfaces and colloids.
2015 Jul; 31(28):7707-11. doi:
10.1021/acs.langmuir.5b01676. [PMID: 26146884] - Qingtao Liu, Jinfeng Wang, Yao-Da Dong, Ben J Boyd. Using a selective cadmium-binding peplipid to create responsive liquid crystalline nanomaterials.
Journal of colloid and interface science.
2015 Jul; 449(?):122-9. doi:
10.1016/j.jcis.2014.11.063. [PMID: 25554088] - Intan Diana Mat Azmi, Linping Wu, Peter Popp Wibroe, Christa Nilsson, Jesper Østergaard, Stefan Stürup, Bente Gammelgaard, Arto Urtti, Seyed Moein Moghimi, Anan Yaghmur. Modulatory effect of human plasma on the internal nanostructure and size characteristics of liquid-crystalline nanocarriers.
Langmuir : the ACS journal of surfaces and colloids.
2015 May; 31(18):5042-9. doi:
10.1021/acs.langmuir.5b00830. [PMID: 25884233] - Josephine Y T Chong, Xavier Mulet, Daniel J Keddie, Lynne Waddington, Stephen T Mudie, Ben J Boyd, Calum J Drummond. Novel steric stabilizers for lyotropic liquid crystalline nanoparticles: PEGylated-phytanyl copolymers.
Langmuir : the ACS journal of surfaces and colloids.
2015 Mar; 31(9):2615-29. doi:
10.1021/la501471z. [PMID: 25068381] - Yi-Lynn Liang, Charlotte E Conn, Calum J Drummond, Connie Darmanin. Uptake of the butyrate receptors, GPR41 and GPR43, in lipidic bicontinuous cubic phases suitable for in meso crystallization.
Journal of colloid and interface science.
2015 Mar; 441(?):78-84. doi:
10.1016/j.jcis.2014.11.006. [PMID: 25490566] - Jiali Zhai, Judith A Scoble, Nan Li, George Lovrecz, Lynne J Waddington, Nhiem Tran, Benjamin W Muir, Gregory Coia, Nigel Kirby, Calum J Drummond, Xavier Mulet. Epidermal growth factor receptor-targeted lipid nanoparticles retain self-assembled nanostructures and provide high specificity.
Nanoscale.
2015 Feb; 7(7):2905-13. doi:
10.1039/c4nr05200e. [PMID: 25516406] - Meng Bu, Jingling Tang, Yinghui Wei, Yanhui Sun, Xinyu Wang, Linhua Wu, Hongzhuo Liu. Enhanced bioavailability of nerve growth factor with phytantriol lipid-based crystalline nanoparticles in cochlea.
International journal of nanomedicine.
2015; 10(?):6879-89. doi:
10.2147/ijn.s82944. [PMID: 26604754] - Wye-Khay Fong, Tracey L Hanley, Benjamin Thierry, Adam Tilley, Nigel Kirby, Lynne J Waddington, Ben J Boyd. Understanding the photothermal heating effect in non-lamellar liquid crystalline systems, and the design of new mixed lipid systems for photothermal on-demand drug delivery.
Physical chemistry chemical physics : PCCP.
2014 Dec; 16(45):24936-53. doi:
10.1039/c4cp03635b. [PMID: 25325902] - Joanne D Du, Qingtao Liu, Stefan Salentinig, Tri-Hung Nguyen, Ben J Boyd. A novel approach to enhance the mucoadhesion of lipid drug nanocarriers for improved drug delivery to the buccal mucosa.
International journal of pharmaceutics.
2014 Aug; 471(1-2):358-65. doi:
10.1016/j.ijpharm.2014.05.044. [PMID: 24879939] - Nicole Bye, Oliver E Hutt, Tracey M Hinton, Durga P Acharya, Lynne J Waddington, Bradford A Moffat, David K Wright, Hong X Wang, Xavier Mulet, Benjamin W Muir. Nitroxide-loaded hexosomes provide MRI contrast in vivo.
Langmuir : the ACS journal of surfaces and colloids.
2014 Jul; 30(29):8898-906. doi:
10.1021/la5007296. [PMID: 24979524] - Christa Nilsson, Jesper Østergaard, Susan Weng Larsen, Claus Larsen, Arto Urtti, Anan Yaghmur. PEGylation of phytantriol-based lyotropic liquid crystalline particles--the effect of lipid composition, PEG chain length, and temperature on the internal nanostructure.
Langmuir : the ACS journal of surfaces and colloids.
2014 Jun; 30(22):6398-407. doi:
10.1021/la501411w. [PMID: 24833115] - Wye Khay Fong, Stefan Salentinig, Clive A Prestidge, Raffaele Mezzenga, Adrian Hawley, Ben J Boyd. Generation of geometrically ordered lipid-based liquid-crystalline nanoparticles using biologically relevant enzymatic processing.
Langmuir : the ACS journal of surfaces and colloids.
2014 May; 30(19):5373-7. doi:
10.1021/la5003447. [PMID: 24783947] - Qingtao Liu, Yao-Da Dong, Tracey L Hanley, Ben J Boyd. Sensitivity of nanostructure in charged cubosomes to phase changes triggered by ionic species in solution.
Langmuir : the ACS journal of surfaces and colloids.
2013 Nov; 29(46):14265-73. doi:
10.1021/la402426y. [PMID: 24111826] - Kristian J Tangso, Wye-Khay Fong, Tamim Darwish, Nigel Kirby, Ben J Boyd, Tracey L Hanley. Novel spiropyran amphiphiles and their application as light-responsive liquid crystalline components.
The journal of physical chemistry. B.
2013 Sep; 117(35):10203-10. doi:
10.1021/jp403840m. [PMID: 23909814] - Wye-Khay Fong, Tracey L Hanley, Benjamin Thierry, Nigel Kirby, Lynne J Waddington, Ben J Boyd. Controlling the nanostructure of gold nanorod-lyotropic liquid-crystalline hybrid materials using near-infrared laser irradiation.
Langmuir : the ACS journal of surfaces and colloids.
2012 Oct; 28(40):14450-60. doi:
10.1021/la302901q. [PMID: 22970861] - Christa Nilsson, Katarina Edwards, Jonny Eriksson, Susan Weng Larsen, Jesper Østergaard, Claus Larsen, Arto Urtti, Anan Yaghmur. Characterization of oil-free and oil-loaded liquid-crystalline particles stabilized by negatively charged stabilizer citrem.
Langmuir : the ACS journal of surfaces and colloids.
2012 Aug; 28(32):11755-66. doi:
10.1021/la3021244. [PMID: 22831645] - Benjamin W Muir, Durga P Acharya, Danielle F Kennedy, Xavier Mulet, Richard A Evans, Suzanne M Pereira, Kim L Wark, Ben J Boyd, Tri-Hung Nguyen, Tracey M Hinton, Lynne J Waddington, Nigel Kirby, David K Wright, Hong X Wang, Gary F Egan, Bradford A Moffat. Metal-free and MRI visible theranostic lyotropic liquid crystal nitroxide-based nanoparticles.
Biomaterials.
2012 Mar; 33(9):2723-33. doi:
10.1016/j.biomaterials.2011.12.018. [PMID: 22209558] - Jiali Zhai, Lynne Waddington, Tim J Wooster, Marie-Isabel Aguilar, Ben J Boyd. Revisiting β-casein as a stabilizer for lipid liquid crystalline nanostructured particles.
Langmuir : the ACS journal of surfaces and colloids.
2011 Dec; 27(24):14757-66. doi:
10.1021/la203061f. [PMID: 22026367] - Stephanie Phan, Wye-Khay Fong, Nigel Kirby, Tracey Hanley, Ben J Boyd. Evaluating the link between self-assembled mesophase structure and drug release.
International journal of pharmaceutics.
2011 Dec; 421(1):176-82. doi:
10.1016/j.ijpharm.2011.09.022. [PMID: 21963475] - S B Rizwan, D Assmus, A Boehnke, T Hanley, B J Boyd, T Rades, S Hook. Preparation of phytantriol cubosomes by solvent precursor dilution for the delivery of protein vaccines.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2011 Sep; 79(1):15-22. doi:
10.1016/j.ejpb.2010.12.034. [PMID: 21237267] - Tri-Hung Nguyen, Tracey Hanley, Christopher J H Porter, Ben J Boyd. Nanostructured liquid crystalline particles provide long duration sustained-release effect for a poorly water soluble drug after oral administration.
Journal of controlled release : official journal of the Controlled Release Society.
2011 Jul; 153(2):180-6. doi:
10.1016/j.jconrel.2011.03.033. [PMID: 21497623] - Yao-Da Dong, Ian Larson, Timothy J Barnes, Clive A Prestidge, Ben J Boyd. Adsorption of nonlamellar nanostructured liquid-crystalline particles to biorelevant surfaces for improved delivery of bioactive compounds.
ACS applied materials & interfaces.
2011 May; 3(5):1771-80. doi:
10.1021/am2003069. [PMID: 21506614] - Adam Tilley, Yao-Da Dong, Heinz Amenitsch, Michael Rappolt, Ben J Boyd. Transfer of lipid and phase reorganisation in self-assembled liquid crystal nanostructured particles based on phytantriol.
Physical chemistry chemical physics : PCCP.
2011 Feb; 13(8):3026-32. doi:
10.1039/c0cp01724h. [PMID: 21240427] - Hsin-Hui Shen, Jonathan G Crowston, Florian Huber, Simon Saubern, Keith M McLean, Patrick G Hartley. The influence of dipalmitoyl phosphatidylserine on phase behaviour of and cellular response to lyotropic liquid crystalline dispersions.
Biomaterials.
2010 Dec; 31(36):9473-81. doi:
10.1016/j.biomaterials.2010.08.030. [PMID: 20880581] - Tri-Hung Nguyen, Tracey Hanley, Christopher J H Porter, Ian Larson, Ben J Boyd. Phytantriol and glyceryl monooleate cubic liquid crystalline phases as sustained-release oral drug delivery systems for poorly water-soluble drugs II. In-vivo evaluation.
The Journal of pharmacy and pharmacology.
2010 Jul; 62(7):856-65. doi:
10.1211/jpp.62.07.0006. [PMID: 20636873] - Tri-Hung Nguyen, Tracey Hanley, Christopher J H Porter, Ian Larson, Ben J Boyd. Phytantriol and glyceryl monooleate cubic liquid crystalline phases as sustained-release oral drug delivery systems for poorly water soluble drugs I. Phase behaviour in physiologically-relevant media.
The Journal of pharmacy and pharmacology.
2010 Jul; 62(7):844-55. doi:
10.1211/jpp.62.06.0005. [PMID: 20636872] - Fátima O Costa-Balogh, Emma Sparr, João José Simões Sousa, Alberto Canelas Pais. Drug release from lipid liquid crystalline phases: relation with phase behavior.
Drug development and industrial pharmacy.
2010 Apr; 36(4):470-81. doi:
10.3109/03639040903261997. [PMID: 19848561] - S B Rizwan, T Hanley, B J Boyd, T Rades, S Hook. Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: Characterisation, swelling and release kinetics.
Journal of pharmaceutical sciences.
2009 Nov; 98(11):4191-204. doi:
10.1002/jps.21724. [PMID: 19340889] - Wye-Khay Fong, Tracey Hanley, Ben J Boyd. Stimuli responsive liquid crystals provide 'on-demand' drug delivery in vitro and in vivo.
Journal of controlled release : official journal of the Controlled Release Society.
2009 May; 135(3):218-26. doi:
10.1016/j.jconrel.2009.01.009. [PMID: 19331865] - Pauline Vandoolaeghe, Justas Barauskas, Markus Johnsson, Fredrïk Tiberg, Tommy Nylander. Interaction between lamellar (vesicles) and nonlamellar lipid liquid-crystalline nanoparticles as studied by time-resolved small-angle X-ray diffraction.
Langmuir : the ACS journal of surfaces and colloids.
2009 Apr; 25(7):3999-4008. doi:
10.1021/la802768q. [PMID: 19714888] - Aurelia W Dong, Carlos Pascual-Izarra, Steven J Pas, Anita J Hill, Ben J Boyd, Calum J Drummond. Positron annihilation lifetime spectroscopy (PALS) as a characterization technique for nanostructured self-assembled amphiphile systems.
The journal of physical chemistry. B.
2009 Jan; 113(1):84-91. doi:
10.1021/jp805280r. [PMID: 19086790] - Kathy W Y Lee, Tri-Hung Nguyen, Tracey Hanley, Ben J Boyd. Nanostructure of liquid crystalline matrix determines in vitro sustained release and in vivo oral absorption kinetics for hydrophilic model drugs.
International journal of pharmaceutics.
2009 Jan; 365(1-2):190-9. doi:
10.1016/j.ijpharm.2008.08.022. [PMID: 18790030] - Johanna Bender, Carl Simonsson, Maria Smedh, Sven Engström, Marica B Ericson. Lipid cubic phases in topical drug delivery: visualization of skin distribution using two-photon microscopy.
Journal of controlled release : official journal of the Controlled Release Society.
2008 Aug; 129(3):163-9. doi:
10.1016/j.jconrel.2008.04.020. [PMID: 18538886] - Audrius Misiūnas, Zita Talaikyte, Gediminas Niaura, Valdemaras Razumas, Tommy Nylander. Thermomyces lanuginosus lipase in the liquid-crystalline phases of aqueous phytantriol: X-ray diffraction and vibrational spectroscopic studies.
Biophysical chemistry.
2008 May; 134(3):144-56. doi:
10.1016/j.bpc.2008.02.002. [PMID: 18329781] - Pia Wadsten-Hindrichsen, Johanna Bender, Johan Unga, Sven Engström. Aqueous self-assembly of phytantriol in ternary systems: effect of monoolein, distearoylphosphatidylglycerol and three water-miscible solvents.
Journal of colloid and interface science.
2007 Nov; 315(2):701-13. doi:
10.1016/j.jcis.2007.07.011. [PMID: 17655855] - Anastasios Polyzos, Malcolm R Alderton, Raymond M Dawson, Patrick G Hartley. Biofunctionalized surfactant mesophases as polyvalent inhibitors of cholera toxin.
Bioconjugate chemistry.
2007 Sep; 18(5):1442-9. doi:
10.1021/bc0700640. [PMID: 17715991] - S B Rizwan, Y-D Dong, B J Boyd, T Rades, S Hook. Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM).
Micron (Oxford, England : 1993).
2007; 38(5):478-85. doi:
10.1016/j.micron.2006.08.003. [PMID: 17011783] - Yao-Da Dong, Ian Larson, Tracey Hanley, Ben J Boyd. Bulk and dispersed aqueous phase behavior of phytantriol: effect of vitamin E acetate and F127 polymer on liquid crystal nanostructure.
Langmuir : the ACS journal of surfaces and colloids.
2006 Nov; 22(23):9512-8. doi:
10.1021/la061706v. [PMID: 17073473] - Audrius Misiūnas, Gediminas Niaura, Zita Talaikyte, Olegas Eicher-Lorka, Valdemaras Razumas. Infrared and Raman bands of phytantriol as markers of hydrogen bonding and interchain interaction.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2005 Dec; 62(4-5):945-57. doi:
10.1016/j.saa.2005.03.024. [PMID: 15961342]