apigenin-7-D-glucoside (BioDeep_00000344577)
代谢物信息卡片
apigenin-7-D-glucoside
化学式: C21H24O9 (420.14202539999997)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: OCC1OC(Oc2cc(O)c3c(c2)OC(c2ccc(O)cc2)CC3)C(O)C(O)C1O
InChI:
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xuerong Zhao, Zhuoya Wang, Guanlin Wu, Lianhong Yin, Lina Xu, Ning Wang, Jinyong Peng. Apigenin-7-glucoside-loaded nanoparticle alleviates intestinal ischemia-reperfusion by ATF3/SLC7A11-mediated ferroptosis.
Journal of controlled release : official journal of the Controlled Release Society.
2024 Jan; 366(?):182-193. doi:
10.1016/j.jconrel.2023.12.038. [PMID: 38145659] - Tawakaltu Abdulrasheed-Adeleke, Bashir Lawal, Eyuwa Ignatius Agwupuye, Yucheng Kuo, Amarachi Mary Eni, Okwukwe Faith Ekoh, Halimat Yusuf Lukman, Amos S Onikanni, Femi Olawale, Sani Saidu, Yunusa O Ibrahim, Maliha Abdullah Saleh Al Ghamdi, Sarah S Aggad, Abdulrahman A Alsayegh, Nada H Aljarba, Gaber El-Saber Batiha, Alexander T H Wu, Hsu-Shan Huang. Apigetrin-enriched Pulmeria alba extract prevents assault of STZ on pancreatic β-cells and neuronal oxidative stress with concomitant attenuation of tissue damage and suppression of inflammation in the brain of diabetic rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Mar; 162(?):114582. doi:
10.1016/j.biopha.2023.114582. [PMID: 36989727] - Miao-Miao Liu, Run-Hui Ma, Zhi-Jing Ni, Kiran Thakur, Carlos L Cespedes-Acuña, Li Jiang, Zhao-Jun Wei. Apigenin 7-O-glucoside promotes cell apoptosis through the PTEN/PI3K/AKT pathway and inhibits cell migration in cervical cancer HeLa cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2020 Dec; 146(?):111843. doi:
10.1016/j.fct.2020.111843. [PMID: 33152472] - Wei Wang, Ru-Feng Yue, Zhen Jin, Li-Min He, Rong Shen, Dan Du, You-Zhi Tang. Efficiency comparison of apigenin-7-O-glucoside and trolox in antioxidative stress and anti-inflammatory properties.
The Journal of pharmacy and pharmacology.
2020 Nov; 72(11):1645-1656. doi:
10.1111/jphp.13347. [PMID: 32743812] - Ewa Witkowska-Banaszczak, Violetta Krajka-Kuźniak, Katarzyna Papierska. The effect of luteolin 7-glucoside, apigenin 7-glucoside and Succisa pratensis extracts on NF-κB activation and α-amylase activity in HepG2 cells.
Acta biochimica Polonica.
2020 Mar; 67(1):41-47. doi:
10.18388/abp.2020_2894. [PMID: 32129972] - Perihan Koysu, Nusret Genc, Mahfuz Elmastas, Huseyin Aksit, Ramazan Erenler. Isolation, identification of secondary metabolites from Salvia absconditiflora and evaluation of their antioxidative properties.
Natural product research.
2019 Dec; 33(24):3592-3595. doi:
10.1080/14786419.2018.1488700. [PMID: 30445824] - Beligh Mechri, Meriem Tekaya, Mohamed Hammami, Hechmi Chehab. Root verbascoside and oleuropein are potential indicators of drought resistance in olive trees (Olea europaea L.).
Plant physiology and biochemistry : PPB.
2019 Aug; 141(?):407-414. doi:
10.1016/j.plaphy.2019.06.024. [PMID: 31228797] - Xinqiao Zhan, Qingwen Shen, Jie Chen, Pei Yang, Xuemin Wang, Yueyun Hong. Rice sulfoquinovosyltransferase SQD2.1 mediates flavonoid glycosylation and enhances tolerance to osmotic stress.
Plant, cell & environment.
2019 07; 42(7):2215-2230. doi:
10.1111/pce.13554. [PMID: 30942482] - M Villalva, L Jaime, D Villanueva-Bermejo, B Lara, T Fornari, G Reglero, S Santoyo. Supercritical anti-solvent fractionation for improving antioxidant and anti-inflammatory activities of an Achillea millefolium L. extract.
Food research international (Ottawa, Ont.).
2019 01; 115(?):128-134. doi:
10.1016/j.foodres.2018.08.027. [PMID: 30599924] - Fatma Hadrich, Sami Sayadi. Apigetrin inhibits adipogenesis in 3T3-L1 cells by downregulating PPARγ and CEBP-α.
Lipids in health and disease.
2018 Apr; 17(1):95. doi:
10.1186/s12944-018-0738-0. [PMID: 29695233] - Xinqiao Zhan, Qingwen Shen, Xuemin Wang, Yueyun Hong. The Sulfoquinovosyltransferase-like Enzyme SQD2.2 is Involved in Flavonoid Glycosylation, Regulating Sugar Metabolism and Seed Setting in Rice.
Scientific reports.
2017 07; 7(1):4685. doi:
10.1038/s41598-017-04002-2. [PMID: 28680100] - Minjuan Bian, Yong Zhang, Xiaoye Du, Jing Xu, Jingang Cui, Jiangping Gu, Weiliang Zhu, Teng Zhang, Yu Chen. Apigenin-7-diglucuronide protects retinas against bright light-induced photoreceptor degeneration through the inhibition of retinal oxidative stress and inflammation.
Brain research.
2017 05; 1663(?):141-150. doi:
10.1016/j.brainres.2017.03.019. [PMID: 28336272] - Lucas B Bolzon, Joicy S Dos Santos, Denise B Silva, Eduardo J Crevelin, Luiz A B Moraes, Norberto P Lopes, Marilda D Assis. Apigenin-7-O-glucoside oxidation catalyzed by P450-bioinspired systems.
Journal of inorganic biochemistry.
2017 05; 170(?):117-124. doi:
10.1016/j.jinorgbio.2017.02.016. [PMID: 28236787] - Yanrong Zhu, Shouyin Di, Wei Hu, Yingda Feng, Qing Zhou, Bing Gong, Xinlong Tang, Juntian Liu, Wei Zhang, Miaomiao Xi, Lin Jiang, Chao Guo, Jingyi Cao, Chongxi Fan, Zhiqiang Ma, Yang Yang, Aidong Wen. A new flavonoid glycoside (APG) isolated from Clematis tangutica attenuates myocardial ischemia/reperfusion injury via activating PKCε signaling.
Biochimica et biophysica acta. Molecular basis of disease.
2017 03; 1863(3):701-711. doi:
10.1016/j.bbadis.2016.12.013. [PMID: 28024940] - Etil Guzelmeric, Petar Ristivojević, Irena Vovk, Dušanka Milojković-Opsenica, Erdem Yesilada. Quality assessment of marketed chamomile tea products by a validated HPTLC method combined with multivariate analysis.
Journal of pharmaceutical and biomedical analysis.
2017 Jan; 132(?):35-45. doi:
10.1016/j.jpba.2016.09.030. [PMID: 27693951] - Hye-Sun Lim, Ohn-Soon Kim, Bu-Yeo Kim, Soo-Jin Jeong. Apigetrin from Scutellaria baicalensis Georgi Inhibits Neuroinflammation in BV-2 Microglia and Exerts Neuroprotective Effect in HT22 Hippocampal Cells.
Journal of medicinal food.
2016 Nov; 19(11):1032-1040. doi:
10.1089/jmf.2016.0074. [PMID: 27845861] - Bo Liu, Yu-Zhen Xie, Xiao-Xiu Li, Ying-Ying Sun, Fang Xu, Teng-Fei Ji. [Chemical constituents of Myripnois dioica].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2016 Sep; 41(17):3260-3264. doi:
10.4268/cjcmm20161723. [PMID: 28920380] - Malek Besbes Hlila, Habib Mosbah, Nahla Zanina, Aymen Ben Nejma, Hichem Ben Jannet, Mahjoub Aouni, Boulbaba Selmi. Characterisation of phenolic antioxidants in Scabiosa arenaria flowers by LC-ESI-MS/MS and NMR.
The Journal of pharmacy and pharmacology.
2016 Jul; 68(7):932-40. doi:
10.1111/jphp.12561. [PMID: 27230582] - Nouha Nasr-Bouzaiene, Aicha Sassi, Ahmed Bedoui, Mounira Krifa, Leila Chekir-Ghedira, Kamel Ghedira. Immunomodulatory and cellular antioxidant activities of pure compounds from Teucrium ramosissimum Desf.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.
2016 Jun; 37(6):7703-12. doi:
10.1007/s13277-015-4635-0. [PMID: 26692099] - Medine Gulluce, Furkan Orhan, Derya Yanmis, Tulin Arasoglu, Zuhal Guvenalp, Lutfiye Omur Demirezer. Isolation of a flavonoid, apigenin 7-O-glucoside, from Mentha longifolia (L.) Hudson subspecies longifolia and its genotoxic potency.
Toxicology and industrial health.
2015 Sep; 31(9):831-40. doi:
10.1177/0748233713475511. [PMID: 23377117] - Mihyang Kim, Jaekwan Lee, Jaehong Han. Deglycosylation of isoflavone C-glycosides by newly isolated human intestinal bacteria.
Journal of the science of food and agriculture.
2015 Jul; 95(9):1925-31. doi:
10.1002/jsfa.6900. [PMID: 25199800] - Imen Samet, Myra O Villareal, Hideko Motojima, Junkyu Han, Sami Sayadi, Hiroko Isoda. Olive leaf components apigenin 7-glucoside and luteolin 7-glucoside direct human hematopoietic stem cell differentiation towards erythroid lineage.
Differentiation; research in biological diversity.
2015 Jun; 89(5):146-55. doi:
10.1016/j.diff.2015.07.001. [PMID: 26299581] - Qiang Wei, Xiao-ying Ji, Fei Xu, Qian-rong Li, Hao Yin. [Chemical Constituents from Leaves of Hibiscus syriacus and Their α-Glucosidase Inhibitory Activities].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2015 May; 38(5):975-9. doi:
. [PMID: 26767290] - Etil Guzelmeric, Irena Vovk, Erdem Yesilada. Development and validation of an HPTLC method for apigenin 7-O-glucoside in chamomile flowers and its application for fingerprint discrimination of chamomile-like materials.
Journal of pharmaceutical and biomedical analysis.
2015 Mar; 107(?):108-18. doi:
10.1016/j.jpba.2014.12.021. [PMID: 25575175] - Gülcan Ozkan, Mehmet Musa Ozcan. Some phenolic compounds of extracts obtained from Origanum species growing in Turkey.
Environmental monitoring and assessment.
2014 Aug; 186(8):4947-57. doi:
10.1007/s10661-014-3750-5. [PMID: 24691738] - Hui-Peng Song, Hui Zhang, Yu Fu, Hua-yan Mo, Mu Zhang, Jun Chen, Ping Li. Screening for selective inhibitors of xanthine oxidase from Flos Chrysanthemum using ultrafiltration LC-MS combined with enzyme channel blocking.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2014 Jun; 961(?):56-61. doi:
10.1016/j.jchromb.2014.05.001. [PMID: 24861872] - Dinesh Kumar, Zulfiqar Ali Bhat. Apigenin 7-glucoside from Stachys tibetica Vatke and its anxiolytic effect in rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2014 Jun; 21(7):1010-4. doi:
10.1016/j.phymed.2013.12.001. [PMID: 24462214] - Yan-Xia Yang, Fu-Lin Yan, Xiang Wang. [Chemical constituents from Punica granatum flowers].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2014 May; 37(5):804-7. doi:
. [PMID: 25335287] - Eri Nakazaki, Soninkhishig Tsolmon, Junkyu Han, Hiroko Isoda. Proteomic study of granulocytic differentiation induced by apigenin 7-glucoside in human promyelocytic leukemia HL-60 cells.
European journal of nutrition.
2013 Feb; 52(1):25-35. doi:
10.1007/s00394-011-0282-4. [PMID: 22113421] - Zaixing Chen, Xixiang Ying, Shu Meng, Xu Zhu, Hong Jiang, Qishen Cao, Lin Wang, Fanhao Meng. LC determination of luteolin-7-O-β-D-glucoside and apigenin-7-O-β-D-glucoside in rat plasma after administration of Humulus scandens extract and its application to pharmacokinetic studies.
Natural product research.
2012; 26(6):530-9. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2011 Dec; 49(12):3328-35. doi:
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Journal of food science.
2011 Nov; 76(9):T212-7. doi:
10.1111/j.1750-3841.2011.02405.x. [PMID: 22416730] - Shan Qin, Xuesen Wen. [Simultaneous determination of 6 active components in Chrysanthemum morifolium by HPLC].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2011 Jun; 36(11):1474-7. doi:
10.4268/cjcmm20111115. [PMID: 22779181] - Mostafa Hojati, Seyed Ali Mohammad Modarres-Sanavy, Faezeh Ghanati, Mehdi Panahi. Hexaconazole induces antioxidant protection and apigenin-7-glucoside accumulation in Matricaria chamomilla plants subjected to drought stress.
Journal of plant physiology.
2011 May; 168(8):782-91. doi:
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Archives of pharmacal research.
2011 May; 34(5):741-6. doi:
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Bulletin of experimental biology and medicine.
2011 Apr; 150(6):714-7. doi:
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2010 Jan; 33(1):58-60. doi:
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Annals of botany.
2009 Oct; 104(5):853-61. doi:
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The Journal of nutrition.
2009 Jun; 139(6):1095-102. doi:
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Journal of natural medicines.
2008 Apr; 62(2):247-8. doi:
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2008 Mar; 33(5):526-30. doi:
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Journal of agricultural and food chemistry.
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Journal of ethnopharmacology.
2007 Sep; 113(2):312-7. doi:
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2006 Nov; 31(21):1772-5. doi:
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Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2005 Dec; 125(12):1005-8. doi:
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Biomedical and environmental sciences : BES.
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Phytochemical analysis : PCA.
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