(±)-Glycerol 1,2-diacetate (BioDeep_00000034008)
human metabolite Endogenous Volatile Flavor Compounds
代谢物信息卡片
化学式: C7H12O5 (176.06847019999998)
中文名称: 1,2,3-丙三醇,二乙酸酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)OCC(CO)OC(=O)C
InChI: InChI=1S/C7H12O5/c1-5(9)11-4-7(3-8)12-6(2)10/h7-8H,3-4H2,1-2H3
描述信息
(±)-Glycerol 1,2-diacetate is a solvent; used for decaffeinating coffe
Solv.; used for decaffeinating coffee.
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:173246
- PubChem: 66021
- HMDB: HMDB0031712
- foodb: FDB008375
- chemspider: 59412
- CAS: 101364-64-1
- CAS: 102-62-5
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Zu-Guo Zheng, Yin-Yue Xu, Wen-Ping Liu, Yang Zhang, Chong Zhang, Han-Ling Liu, Xiao-Yu Zhang, Run-Zhou Liu, Yi-Ping Zhang, Meng-Ying Shi, Hua Yang, Ping Li. Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis.
Cell metabolism.
2023 01; 35(1):101-117.e11. doi:
10.1016/j.cmet.2022.11.012
. [PMID: 36525963] - Klaudia Sztolsztener, Ewa Harasim-Symbor, Adrian Chabowski, Karolina Konstantynowicz-Nowicka. The influence of dexamethasone on hepatic fatty acids metabolism and transport in human steatotic HepG2 cell line exposed to palmitate.
Biochemical and biophysical research communications.
2021 12; 585(?):132-138. doi:
10.1016/j.bbrc.2021.11.044
. [PMID: 34801933] - Guoyan Li, Wan Jun Lee, Chin Ping Tan, Oi Ming Lai, Yong Wang, Chaoying Qiu. Tailored rigidity of W/O Pickering emulsions using diacylglycerol-based surface-active solid lipid nanoparticles.
Food & function.
2021 Nov; 12(23):11732-11746. doi:
10.1039/d1fo01883c
. [PMID: 34698749] - Andrey B Imbs, Peter V Velansky. Lipidomic profiling reveals biosynthetic relationships between phospholipids and diacylglycerol ethers in the deep-sea soft coral Paragorgia arborea.
Scientific reports.
2021 10; 11(1):21285. doi:
10.1038/s41598-021-00876-5
. [PMID: 34711899] - Shailee Jani, Daniel Da Eira, Ishvinder Hadday, George Bikopoulos, Arta Mohasses, Ricardo A de Pinho, Rolando B Ceddia. Distinct mechanisms involving diacylglycerol, ceramides, and inflammation underlie insulin resistance in oxidative and glycolytic muscles from high fat-fed rats.
Scientific reports.
2021 09; 11(1):19160. doi:
10.1038/s41598-021-98819-7
. [PMID: 34580412] - Chaoying Qiu, Mengting Lei, Wan Jun Lee, Ning Zhang, Yong Wang. Fabrication and characterization of stable oleofoam based on medium-long chain diacylglycerol and β-sitosterol.
Food chemistry.
2021 Jul; 350(?):129275. doi:
10.1016/j.foodchem.2021.129275
. [PMID: 33601090] - Jihyun Hwang, Heeju Jun, Seoye Roh, Seong Jae Lee, Jeong Min Mun, Seung Wook Kim, Min-Yu Chung, In-Hwan Kim, Byung Hee Kim. Preparation of Low-Diacylglycerol Cocoa Butter Equivalents by Hexane Fractionation of Palm Stearin and Shea Butter.
Molecules (Basel, Switzerland).
2021 May; 26(11):. doi:
10.3390/molecules26113231
. [PMID: 34072180] - Gergana Deevska, Patrick P Dotson, Mihail Mitov, D Allan Butterfield, Mariana Nikolova-Karakashian. Onset of Senescence and Steatosis in Hepatocytes as a Consequence of a Shift in the Diacylglycerol/Ceramide Balance at the Plasma Membrane.
Cells.
2021 05; 10(6):. doi:
10.3390/cells10061278
. [PMID: 34064003] - Kun Lyu, Dongyan Zhang, Joongyu Song, Xiruo Li, Rachel J Perry, Varman T Samuel, Gerald I Shulman. Short-term overnutrition induces white adipose tissue insulin resistance through sn-1,2-diacylglycerol/PKCε/insulin receptor Thr1160 phosphorylation.
JCI insight.
2021 02; 6(4):. doi:
10.1172/jci.insight.139946
. [PMID: 33411692] - Chiaki Murakami, Fumio Sakane. Sphingomyelin synthase-related protein generates diacylglycerol via the hydrolysis of glycerophospholipids in the absence of ceramide.
The Journal of biological chemistry.
2021 Jan; 296(?):100454. doi:
10.1016/j.jbc.2021.100454
. [PMID: 33621517] - Abudukadier Abulizi, Daniel F Vatner, Zhang Ye, Yongliang Wang, Joao-Paulo Camporez, Dongyan Zhang, Mario Kahn, Kun Lyu, Alaa Sirwi, Gary W Cline, M Mahmood Hussain, Patricia Aspichueta, Varman T Samuel, Gerald I Shulman. Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice.
Journal of lipid research.
2020 12; 61(12):1565-1576. doi:
10.1194/jlr.ra119000586
. [PMID: 32907986] - Kun Lyu, Ye Zhang, Dongyan Zhang, Mario Kahn, Kasper W Ter Horst, Marcos R S Rodrigues, Rafael C Gaspar, Sandro M Hirabara, Panu K Luukkonen, Seohyuk Lee, Sanjay Bhanot, Jesse Rinehart, Niels Blume, Morten Grønbech Rasch, Mireille J Serlie, Jonathan S Bogan, Gary W Cline, Varman T Samuel, Gerald I Shulman. A Membrane-Bound Diacylglycerol Species Induces PKCϵ-Mediated Hepatic Insulin Resistance.
Cell metabolism.
2020 10; 32(4):654-664.e5. doi:
10.1016/j.cmet.2020.08.001
. [PMID: 32882164] - Antonietta Fazio, Eric Owusu Obeng, Isabella Rusciano, Maria Vittoria Marvi, Matteo Zoli, Sara Mongiorgi, Giulia Ramazzotti, Matilde Yung Follo, James A McCubrey, Lucio Cocco, Lucia Manzoli, Stefano Ratti. Subcellular Localization Relevance and Cancer-Associated Mechanisms of Diacylglycerol Kinases.
International journal of molecular sciences.
2020 Jul; 21(15):. doi:
10.3390/ijms21155297
. [PMID: 32722576] - Han Lu, Tingting Guo, Yawei Fan, Zeyuan Deng, Ting Luo, Hongyan Li. Effects of diacylglycerol and triacylglycerol from peanut oil and coconut oil on lipid metabolism in mice.
Journal of food science.
2020 Jun; 85(6):1907-1914. doi:
10.1111/1750-3841.15159
. [PMID: 32421231] - Katarzyna Kolczynska, Angel Loza-Valdes, Izabela Hawro, Grzegorz Sumara. Diacylglycerol-evoked activation of PKC and PKD isoforms in regulation of glucose and lipid metabolism: a review.
Lipids in health and disease.
2020 May; 19(1):113. doi:
10.1186/s12944-020-01286-8
. [PMID: 32466765] - Mengting Lei, Ning Zhang, Wan Jun Lee, Chin Ping Tan, Oi Ming Lai, Yong Wang, Chaoying Qiu. Non-aqueous foams formed by whipping diacylglycerol stabilized oleogel.
Food chemistry.
2020 May; 312(?):126047. doi:
10.1016/j.foodchem.2019.126047
. [PMID: 31884300] - Milena Schuhmacher, Andreas T Grasskamp, Pavel Barahtjan, Nicolai Wagner, Benoit Lombardot, Jan S Schuhmacher, Pia Sala, Annett Lohmann, Ian Henry, Andrej Shevchenko, Ünal Coskun, Alexander M Walter, André Nadler. Live-cell lipid biochemistry reveals a role of diacylglycerol side-chain composition for cellular lipid dynamics and protein affinities.
Proceedings of the National Academy of Sciences of the United States of America.
2020 04; 117(14):7729-7738. doi:
10.1073/pnas.1912684117
. [PMID: 32213584] - Hyeon-Jun Chang, Jeung-Hee Lee. Emulsification and oxidation stabilities of DAG-rich algae oil-in-water emulsions prepared with the selected emulsifiers.
Journal of the science of food and agriculture.
2020 Jan; 100(1):287-294. doi:
10.1002/jsfa.10037
. [PMID: 31525263] - Jian Xie, Sung-Wan An, Xin Jin, Yuan Gui, Chou-Long Huang. Munc13 mediates klotho-inhibitable diacylglycerol-stimulated exocytotic insertion of pre-docked TRPC6 vesicles.
PloS one.
2020; 15(3):e0229799. doi:
10.1371/journal.pone.0229799
. [PMID: 32134975] - Peter Gajdoš, Jaroslav Hambalko, Jean-Marc Nicaud, Milan Čertík. Overexpression of diacylglycerol acetyltransferase from Euonymus europaeus in Yarrowia lipolytica leads to the production of single-cell oil enriched with 3-acetyl-1,2-diacylglycerols.
Yeast (Chichester, England).
2020 01; 37(1):141-147. doi:
10.1002/yea.3442
. [PMID: 31509617] - Marijana Popović Hadžija, Zdravko Siketić, Mirko Hadžija, Marko Barac, Iva Bogdanović Radović. Study of the diacylglycerol composition in the liver and serum of mice with prediabetes and diabetes using MeV TOF-SIMS.
Diabetes research and clinical practice.
2020 Jan; 159(?):107986. doi:
10.1016/j.diabres.2019.107986
. [PMID: 31866525] - Xiao-Hong Yu, Yuanheng Cai, Jin Chai, Jorg Schwender, John Shanklin. Expression of a Lychee PHOSPHATIDYLCHOLINE:DIACYLGLYCEROL CHOLINEPHOSPHOTRANSFERASE with an Escherichia coli CYCLOPROPANE SYNTHASE Enhances Cyclopropane Fatty Acid Accumulation in Camelina Seeds.
Plant physiology.
2019 07; 180(3):1351-1361. doi:
10.1104/pp.19.00396
. [PMID: 31123096] - Shu Yuan, Sang-Chul Kim, Xianjun Deng, Yueyun Hong, Xuemin Wang. Diacylglycerol kinase and associated lipid mediators modulate rice root architecture.
The New phytologist.
2019 07; 223(1):261-276. doi:
10.1111/nph.15801
. [PMID: 30887532] - Sławomir Grycel, Adam R Markowski, Hady Razak Hady, Piotr Zabielski, Iwona Kojta, Monika Imierska, Jan Górski, Agnieszka U Blachnio-Zabielska. Metformin treatment affects adipocytokine secretion and lipid composition in adipose tissues of diet-induced insulin-resistant rats.
Nutrition (Burbank, Los Angeles County, Calif.).
2019 Jul; 63-64(?):126-133. doi:
10.1016/j.nut.2019.01.019
. [PMID: 30959381] - Peter Reinink, Michael N T Souter, Tan-Yun Cheng, Tamara van Gorkom, Stefanie Lenz, Joanna Kubler-Kielb, Klemen Strle, Kristin Kremer, Steven F T Thijsen, Allen C Steere, Dale I Godfrey, Daniel G Pellicci, D Branch Moody, Ildiko Van Rhijn. CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells.
European journal of immunology.
2019 05; 49(5):737-746. doi:
10.1002/eji.201847949
. [PMID: 30854633] - Kevin Jeanne Dit Fouque, Cesar E Ramirez, Russell L Lewis, Jeremy P Koelmel, Timothy J Garrett, Richard A Yost, Francisco Fernandez-Lima. Effective Liquid Chromatography-Trapped Ion Mobility Spectrometry-Mass Spectrometry Separation of Isomeric Lipid Species.
Analytical chemistry.
2019 04; 91(8):5021-5027. doi:
10.1021/acs.analchem.8b04979
. [PMID: 30896930] - Mariana Cooke, Victoria Casado-Medrano, Jihyae Ann, Jeewoo Lee, Peter M Blumberg, Martin C Abba, Marcelo G Kazanietz. Differential Regulation of Gene Expression in Lung Cancer Cells by Diacyglycerol-Lactones and a Phorbol Ester Via Selective Activation of Protein Kinase C Isozymes.
Scientific reports.
2019 04; 9(1):6041. doi:
10.1038/s41598-019-42581-4
. [PMID: 30988374] - Ditte Søgaard, Marcin Baranowski, Steen Larsen, Michael Taulo Lund, Cathrine Munk Scheuer, Carina Vestergaard Abildskov, Sofie Greve Dideriksen, Flemming Dela, Jørn Wulff Helge. Muscle-Saturated Bioactive Lipids Are Increased with Aging and Influenced by High-Intensity Interval Training.
International journal of molecular sciences.
2019 Mar; 20(5):. doi:
10.3390/ijms20051240
. [PMID: 30871020] - Kristin Möbius, Sina Kazemi, Peter Güntert, Andreas Jakob, Alexander Heckel, Johanna Becker-Baldus, Clemens Glaubitz. Global response of diacylglycerol kinase towards substrate binding observed by 2D and 3D MAS NMR.
Scientific reports.
2019 03; 9(1):3995. doi:
10.1038/s41598-019-40264-8
. [PMID: 30850624] - Hervé Moine, Nicolas Vitale. Of local translation control and lipid signaling in neurons.
Advances in biological regulation.
2019 01; 71(?):194-205. doi:
10.1016/j.jbior.2018.09.005
. [PMID: 30262213] - Qianqian Ma, Sandra B Gabelli, Daniel M Raben. Diacylglycerol kinases: Relationship to other lipid kinases.
Advances in biological regulation.
2019 01; 71(?):104-110. doi:
10.1016/j.jbior.2018.09.014
. [PMID: 30348515] - Tomoyuki Nakano, Satoshi Ogasawara, Toshiaki Tanaka, Yasukazu Hozumi, Atsumi Yamaki, Fumio Sakane, Yasuhito Shirai, Takuro Nakamura, Miyuki Yanaka, Shinji Yamada, Mika K Kaneko, Yukinari Kato, Kaoru Goto. DgMab-6: Antihuman DGKγ Monoclonal Antibody for Immunocytochemistry.
Monoclonal antibodies in immunodiagnosis and immunotherapy.
2018 Nov; 37(5):229-232. doi:
10.1089/mab.2018.0026
. [PMID: 30362931] - Merete B Munk, Daniel M E Munk, Frida Gustavsson, Jens Risbo. Using Ethylcellulose to Structure Oil Droplets in Ice Cream Made with High Oleic Sunflower Oil.
Journal of food science.
2018 Oct; 83(10):2520-2526. doi:
10.1111/1750-3841.14296
. [PMID: 30192011] - Karen Weber, Cecilia Casali, Virginia Gaveglio, Susana Pasquaré, Emanuel Morel Gómez, Leandro Parra, Luciana Erjavec, Cecilia Perazzo, María C Fernández Tome. TAG synthesis and storage under osmotic stress. A requirement for preserving membrane homeostasis in renal cells.
Biochimica et biophysica acta. Molecular and cell biology of lipids.
2018 09; 1863(9):1108-1120. doi:
10.1016/j.bbalip.2018.06.012
. [PMID: 29908368] - Pamela J McFie, Shanna L Banman, Scot J Stone. Diacylglycerol acyltransferase-2 contains a c-terminal sequence that interacts with lipid droplets.
Biochimica et biophysica acta. Molecular and cell biology of lipids.
2018 09; 1863(9):1068-1081. doi:
10.1016/j.bbalip.2018.06.008
. [PMID: 29902571] - Claudia Oellig, Klara Brändle, Wolfgang Schwack. Characterization of E 471 food emulsifiers by high-performance thin-layer chromatography-fluorescence detection.
Journal of chromatography. A.
2018 Jul; 1558(?):69-76. doi:
10.1016/j.chroma.2018.05.010
. [PMID: 29752044] - Sarah Ouahoud, Mitchell D Fiet, Fernando Martínez-Montañés, Christer S Ejsing, Oliver Kuss, Michael Roden, Daniel F Markgraf. Lipid droplet consumption is functionally coupled to vacuole homeostasis independent of lipophagy.
Journal of cell science.
2018 06; 131(11):. doi:
10.1242/jcs.213876
. [PMID: 29678904] - Mariana Cooke, Xiaoling Zhou, Victoria Casado-Medrano, Cynthia Lopez-Haber, Martin J Baker, Rachana Garg, Jihyae Ann, Jeewoo Lee, Peter M Blumberg, Marcelo G Kazanietz. Characterization of AJH-836, a diacylglycerol-lactone with selectivity for novel PKC isozymes.
The Journal of biological chemistry.
2018 06; 293(22):8330-8341. doi:
10.1074/jbc.ra117.000235
. [PMID: 29636415] - Xiao-Long Hu, Xiao-Mei Yu, Hong-Ying Chen, Wei-Qi Li. Turnover of Glycerolipid Metabolite Pool and Seed Viability.
International journal of molecular sciences.
2018 May; 19(5):. doi:
10.3390/ijms19051417
. [PMID: 29747431] - Xiao-Hong Yu, Rebecca E Cahoon, Patrick J Horn, Hai Shi, Richa R Prakash, Yuanheng Cai, Maegan Hearney, Kent D Chapman, Edgar B Cahoon, Jorg Schwender, John Shanklin. Identification of bottlenecks in the accumulation of cyclic fatty acids in camelina seed oil.
Plant biotechnology journal.
2018 04; 16(4):926-938. doi:
10.1111/pbi.12839
. [PMID: 28929610] - Vineet Choudhary, Gonen Golani, Amit S Joshi, Stéphanie Cottier, Roger Schneiter, William A Prinz, Michael M Kozlov. Architecture of Lipid Droplets in Endoplasmic Reticulum Is Determined by Phospholipid Intrinsic Curvature.
Current biology : CB.
2018 03; 28(6):915-926.e9. doi:
10.1016/j.cub.2018.02.020
. [PMID: 29526591] - Ricardo Martín, José Javier Ferrero, Andrea Collado-Alsina, Carolina Aguado, Rafael Luján, Magdalena Torres, José Sánchez-Prieto. Bidirectional modulation of glutamatergic synaptic transmission by metabotropic glutamate type 7 receptors at Schaffer collateral-CA1 hippocampal synapses.
The Journal of physiology.
2018 03; 596(5):921-940. doi:
10.1113/jp275371
. [PMID: 29280494] - Tongcheng Xu, Jianpeng Li, Jiayong Zou, Bin Qiu, Wei Liu, Xinying Lin, Duo Li, Zhenhua Liu, Fangling Du. Rat Small Intestinal Mucosal Epithelial Cells Absorb Dietary 1,3-Diacylglycerol Via Phosphatidic Acid Pathways.
Lipids.
2018 03; 53(3):335-344. doi:
10.1002/lipd.12030
. [PMID: 29701264] - Patrick Rockenfeller, Martin Smolnig, Jutta Diessl, Mina Bashir, Vera Schmiedhofer, Oskar Knittelfelder, Julia Ring, Joakim Franz, Ines Foessl, Muhammad J Khan, René Rost, Wolfgang F Graier, Guido Kroemer, Andreas Zimmermann, Didac Carmona-Gutierrez, Tobias Eisenberg, Sabrina Büttner, Stephan J Sigrist, Ronald P Kühnlein, Sepp D Kohlwein, Campbell W Gourlay, Frank Madeo. Diacylglycerol triggers Rim101 pathway-dependent necrosis in yeast: a model for lipotoxicity.
Cell death and differentiation.
2018 03; 25(4):767-783. doi:
10.1038/s41418-017-0014-2
. [PMID: 29230001] - Leigh Perreault, Sean A Newsom, Allison Strauss, Anna Kerege, Darcy E Kahn, Kathleen A Harrison, Janet K Snell-Bergeon, Travis Nemkov, Angelo D'Alessandro, Matthew R Jackman, Paul S MacLean, Bryan C Bergman. Intracellular localization of diacylglycerols and sphingolipids influences insulin sensitivity and mitochondrial function in human skeletal muscle.
JCI insight.
2018 02; 3(3):. doi:
10.1172/jci.insight.96805
. [PMID: 29415895] - Fumio Sakane, Satoru Mizuno, Daisuke Takahashi, Hiromichi Sakai. Where do substrates of diacylglycerol kinases come from? Diacylglycerol kinases utilize diacylglycerol species supplied from phosphatidylinositol turnover-independent pathways.
Advances in biological regulation.
2018 01; 67(?):101-108. doi:
10.1016/j.jbior.2017.09.003
. [PMID: 28918129] - Nils G Løvsletten, Siril S Bakke, Eili T Kase, D Margriet Ouwens, G Hege Thoresen, Arild C Rustan. Increased triacylglycerol - Fatty acid substrate cycling in human skeletal muscle cells exposed to eicosapentaenoic acid.
PloS one.
2018; 13(11):e0208048. doi:
10.1371/journal.pone.0208048
. [PMID: 30496314] - Sébastien Pellaud, Alexandre Bory, Valentin Chabert, Joëlle Romanens, Laurie Chaisse-Leal, Anh Vu Doan, Lucas Frey, Andrea Gust, Katharina M Fromm, Laurent Mène-Saffrané. WRINKLED1 and ACYL-COA:DIACYLGLYCEROL ACYLTRANSFERASE1 regulate tocochromanol metabolism in Arabidopsis.
The New phytologist.
2018 Jan; 217(1):245-260. doi:
10.1111/nph.14856
. [PMID: 29105089] - Boubacar Benziane, Melissa L Borg, Robby Z Tom, Isabelle Riedl, Julie Massart, Marie Björnholm, Marc Gilbert, Alexander V Chibalin, Juleen R Zierath. DGKζ deficiency protects against peripheral insulin resistance and improves energy metabolism.
Journal of lipid research.
2017 12; 58(12):2324-2333. doi:
10.1194/jlr.m079723
. [PMID: 29066466] - Tam N T Tran, Jennifer Shelton, Susan Brown, Timothy P Durrett. Membrane topology and identification of key residues of EaDAcT, a plant MBOAT with unusual substrate specificity.
The Plant journal : for cell and molecular biology.
2017 Oct; 92(1):82-94. doi:
10.1111/tpj.13636
. [PMID: 28715115] - Shinichiro Saito, Atsuko Mori, Noriko Osaki, Yoshihisa Katsuragi. Diacylglycerol Enhances the Effects of Alpha-Linolenic Acid Against Visceral Fat: A Double-Blind Randomized Controlled Trial.
Obesity (Silver Spring, Md.).
2017 10; 25(10):1667-1675. doi:
10.1002/oby.21938
. [PMID: 28851088] - Nami Ohashi, Ryosuke Kobayashi, Wataru Nomura, Takuya Kobayakawa, Agnes Czikora, Brienna K Herold, Nancy E Lewin, Peter M Blumberg, Hirokazu Tamamura. Synthesis and Evaluation of Dimeric Derivatives of Diacylglycerol-Lactones as Protein Kinase C Ligands.
Bioconjugate chemistry.
2017 08; 28(8):2135-2144. doi:
10.1021/acs.bioconjchem.7b00299
. [PMID: 28671468] - Richard M Epand. Features of the Phosphatidylinositol Cycle and its Role in Signal Transduction.
The Journal of membrane biology.
2017 08; 250(4):353-366. doi:
10.1007/s00232-016-9909-y
. [PMID: 27278236] - Joop E M Vermeer, Ringo van Wijk, Joachim Goedhart, Niko Geldner, Joanne Chory, Theodorus W J Gadella, Teun Munnik. In Vivo Imaging of Diacylglycerol at the Cytoplasmic Leaflet of Plant Membranes.
Plant & cell physiology.
2017 Jul; 58(7):1196-1207. doi:
10.1093/pcp/pcx012
. [PMID: 28158855] - Zhengping Ma, Joelle M Onorato, Luping Chen, David W Nelson, Chi-Liang Eric Yen, Dong Cheng. Synthesis of neutral ether lipid monoalkyl-diacylglycerol by lipid acyltransferases.
Journal of lipid research.
2017 06; 58(6):1091-1099. doi:
10.1194/jlr.m073445
. [PMID: 28420705] - Ali Akoumi, Taha Haffar, Maria Mousterji, Robert Scott Kiss, Nicolas Bousette. Palmitate mediated diacylglycerol accumulation causes endoplasmic reticulum stress, Plin2 degradation, and cell death in H9C2 cardiomyoblasts.
Experimental cell research.
2017 05; 354(2):85-94. doi:
10.1016/j.yexcr.2017.03.032
. [PMID: 28336294] - Takuya Mori, Hiroshi Honda, Shunsuke Ishii, Yoshitaka Koga, Fumiaki Okahara, Shintaro Onishi, Taisuke Kawamoto, Akira Shimotoyodome. Effect of α-linolenic acid-rich diacylglycerol oil on protein kinase C activation in the rat digestive tract and lingual mucosa.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2017 May; 103(?):168-173. doi:
10.1016/j.fct.2017.02.033
. [PMID: 28242340] - Wenyu Yang, Geliang Wang, Jia Li, Philip D Bates, Xuemin Wang, Doug K Allen. Phospholipase Dζ Enhances Diacylglycerol Flux into Triacylglycerol.
Plant physiology.
2017 May; 174(1):110-123. doi:
10.1104/pp.17.00026
. [PMID: 28325849] - Jorge Dinamarca, Orly Levitan, G Kenchappa Kumaraswamy, Desmond S Lun, Paul G Falkowski. Overexpression of a diacylglycerol acyltransferase gene in Phaeodactylum tricornutum directs carbon towards lipid biosynthesis.
Journal of phycology.
2017 04; 53(2):405-414. doi:
10.1111/jpy.12513
. [PMID: 28078675] - Gergana M Deevska, Patrick P Dotson, Alexander A Karakashian, Giorgis Isaac, Mark Wrona, Samuel B Kelly, Alfred H Merrill, Mariana N Nikolova-Karakashian. Novel Interconnections in Lipid Metabolism Revealed by Overexpression of Sphingomyelin Synthase-1.
The Journal of biological chemistry.
2017 03; 292(12):5110-5122. doi:
10.1074/jbc.m116.751602
. [PMID: 28087695] - Steven M Ryckbosch, Paul A Wender, Vijay S Pande. Molecular dynamics simulations reveal ligand-controlled positioning of a peripheral protein complex in membranes.
Nature communications.
2017 02; 8(1):6. doi:
10.1038/s41467-016-0015-8
. [PMID: 28232750] - Doris Höglinger, André Nadler, Per Haberkant, Joanna Kirkpatrick, Martina Schifferer, Frank Stein, Sebastian Hauke, Forbes D Porter, Carsten Schultz. Trifunctional lipid probes for comprehensive studies of single lipid species in living cells.
Proceedings of the National Academy of Sciences of the United States of America.
2017 02; 114(7):1566-1571. doi:
10.1073/pnas.1611096114
. [PMID: 28154130] - Kankana Das, Mahua Ghosh. Structured DAG oil ameliorates renal injury in streptozotocin-induced diabetic rats through inhibition of NF-κB and activation of Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2017 Feb; 100(?):225-238. doi:
10.1016/j.fct.2016.12.033
. [PMID: 28025123] - Maxwell A Ruby, Julie Massart, Devon M Hunerdosse, Milena Schönke, Jorge C Correia, Sharon M Louie, Jorge L Ruas, Erik Näslund, Daniel K Nomura, Juleen R Zierath. Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance.
Cell reports.
2017 01; 18(3):636-646. doi:
10.1016/j.celrep.2016.12.070
. [PMID: 28099843] - Daniel M Raben, Casey N Barber. Phosphatidic acid and neurotransmission.
Advances in biological regulation.
2017 Jan; 63(?):15-21. doi:
10.1016/j.jbior.2016.09.004
. [PMID: 27671966] - Wilhelm Stoffel, Ina Hammels, Bitta Jenke, Erika Binczek, Inga Schmidt-Soltau, Susanne Brodesser, Astrid Schauss, Julia Etich, Juliane Heilig, Frank Zaucke. Neutral sphingomyelinase (SMPD3) deficiency disrupts the Golgi secretory pathway and causes growth inhibition.
Cell death & disease.
2016 11; 7(11):e2488. doi:
10.1038/cddis.2016.385
. [PMID: 27882938] - Annette Karen Serup, Thomas Junker Alsted, Andreas Børsting Jordy, Peter Schjerling, Cecilia Holm, Bente Kiens. Partial Disruption of Lipolysis Increases Postexercise Insulin Sensitivity in Skeletal Muscle Despite Accumulation of DAG.
Diabetes.
2016 10; 65(10):2932-42. doi:
10.2337/db16-0655
. [PMID: 27489310] - Jung-Ah Shin, Mi-Young Lee, Ki-Teak Lee. Oxidation Stability of O/W Emulsion Prepared with Linolenic Acid Enriched Diacylglycerol.
Journal of food science.
2016 Oct; 81(10):C2373-C2380. doi:
10.1111/1750-3841.13421
. [PMID: 27627797] - James Allen Frank, Dmytro A Yushchenko, David J Hodson, Noa Lipstein, Jatin Nagpal, Guy A Rutter, Jeong-Seop Rhee, Alexander Gottschalk, Nils Brose, Carsten Schultz, Dirk Trauner. Photoswitchable diacylglycerols enable optical control of protein kinase C.
Nature chemical biology.
2016 09; 12(9):755-62. doi:
10.1038/nchembio.2141
. [PMID: 27454932] - Karen E Anderson, Veronique Juvin, Jonathan Clark, Len R Stephens, Phillip T Hawkins. Investigating the effect of arachidonate supplementation on the phosphoinositide content of MCF10a breast epithelial cells.
Advances in biological regulation.
2016 09; 62(?):18-24. doi:
10.1016/j.jbior.2015.11.002
. [PMID: 26639089] - Virginia L Gaveglio, Ana C Pascual, Norma M Giusto, Susana J Pasquaré. Age-related changes in retinoic, docosahexaenoic and arachidonic acid modulation in nuclear lipid metabolism.
Archives of biochemistry and biophysics.
2016 08; 604(?):121-7. doi:
10.1016/j.abb.2016.06.017
. [PMID: 27355428] - Po-Lin Yang, Tzu-Han Hsu, Chao-Wen Wang, Rey-Huei Chen. Lipid droplets maintain lipid homeostasis during anaphase for efficient cell separation in budding yeast.
Molecular biology of the cell.
2016 08; 27(15):2368-80. doi:
10.1091/mbc.e16-02-0106
. [PMID: 27307588] - Joanna Nizioł, Krzysztof Ossoliński, Tadeusz Ossoliński, Anna Ossolińska, Vincent Bonifay, Justyna Sekuła, Zygmunt Dobrowolski, Jan Sunner, Iwona Beech, Tomasz Ruman. Surface-Transfer Mass Spectrometry Imaging of Renal Tissue on Gold Nanoparticle Enhanced Target.
Analytical chemistry.
2016 07; 88(14):7365-71. doi:
10.1021/acs.analchem.6b01859
. [PMID: 27329270] - Anne Wuttke, Qian Yu, Anders Tengholm. Autocrine Signaling Underlies Fast Repetitive Plasma Membrane Translocation of Conventional and Novel Protein Kinase C Isoforms in β Cells.
The Journal of biological chemistry.
2016 07; 291(29):14986-95. doi:
10.1074/jbc.m115.698456
. [PMID: 27226533] - Yayuan Xu, Xiaoqing Zhao, Qiang Wang, Zhen Peng, Cao Dong. Thermal profiles, crystallization behaviors and microstructure of diacylglycerol-enriched palm oil blends with diacylglycerol-enriched palm olein.
Food chemistry.
2016 Jul; 202(?):364-72. doi:
10.1016/j.foodchem.2016.01.102
. [PMID: 26920306] - Ricardos Tabet, Enora Moutin, Jérôme A J Becker, Dimitri Heintz, Laetitia Fouillen, Eric Flatter, Wojciech Krężel, Violaine Alunni, Pascale Koebel, Doulaye Dembélé, Flora Tassone, Barbara Bardoni, Jean-Louis Mandel, Nicolas Vitale, Dominique Muller, Julie Le Merrer, Hervé Moine. Fragile X Mental Retardation Protein (FMRP) controls diacylglycerol kinase activity in neurons.
Proceedings of the National Academy of Sciences of the United States of America.
2016 06; 113(26):E3619-28. doi:
10.1073/pnas.1522631113
. [PMID: 27233938] - Greg M Kowalski, Steven Hamley, Ahrathy Selathurai, Joachim Kloehn, David P De Souza, Sean O'Callaghan, Brunda Nijagal, Dedreia L Tull, Malcolm J McConville, Clinton R Bruce. Reversing diet-induced metabolic dysregulation by diet switching leads to altered hepatic de novo lipogenesis and glycerolipid synthesis.
Scientific reports.
2016 06; 6(?):27541. doi:
10.1038/srep27541
. [PMID: 27273128] - Roman A Sidorov, Vasily P Pchelkin, Anatoly V Zhukov, Vladimir D Tsydendambaev. Positional-Species Composition of Diacylglycerol Acetates from Mature Euonymus Seeds.
Chemistry & biodiversity.
2016 Jun; 13(6):789-97. doi:
10.1002/cbdv.201500269
. [PMID: 27151557] - Yueyun Hong, Jian Zhao, Liang Guo, Sang-Chul Kim, Xianjun Deng, Geliang Wang, Gaoyang Zhang, Maoyin Li, Xuemin Wang. Plant phospholipases D and C and their diverse functions in stress responses.
Progress in lipid research.
2016 04; 62(?):55-74. doi:
10.1016/j.plipres.2016.01.002
. [PMID: 26783886] - Jin Liu, Danxiang Han, Kangsup Yoon, Qiang Hu, Yantao Li. Characterization of type 2 diacylglycerol acyltransferases in Chlamydomonas reinhardtii reveals their distinct substrate specificities and functions in triacylglycerol biosynthesis.
The Plant journal : for cell and molecular biology.
2016 Apr; 86(1):3-19. doi:
10.1111/tpj.13143
. [PMID: 26919811] - Violeta B Popov, Francois R Jornayvaz, Emin O Akgul, Shoichi Kanda, Michael J Jurczak, Dongyan Zhang, Abulizi Abudukadier, Sachin K Majumdar, Blas Guigni, Kitt Falk Petersen, Vara Prasad Manchem, Sanjay Bhanot, Gerald I Shulman, Varman T Samuel. Second-generation antisense oligonucleotides against β-catenin protect mice against diet-induced hepatic steatosis and hepatic and peripheral insulin resistance.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2016 Mar; 30(3):1207-17. doi:
10.1096/fj.15-271999
. [PMID: 26644352] - Jin F Qi, Cai H Jia, Jung A Shin, Jeong M Woo, Xiang Y Wang, Jong T Park, Soon T Hong, K-T Lee. Effect of Acylglycerol Composition and Fatty Acyl Chain Length on Lipid Digestion in pH-Stat Digestion Model and Simulated In Vitro Digestion Model.
Journal of food science.
2016 Feb; 81(2):C317-23. doi:
10.1111/1750-3841.13196
. [PMID: 26720174] - Jia-Yu Ke, Rachel M Cole, Essam M Hamad, Yung-Hsuan Hsiao, Bradley M Cotten, Kimerly A Powell, Martha A Belury. Citrus flavonoid, naringenin, increases locomotor activity and reduces diacylglycerol accumulation in skeletal muscle of obese ovariectomized mice.
Molecular nutrition & food research.
2016 Feb; 60(2):313-24. doi:
10.1002/mnfr.201500379
. [PMID: 26573879] - Daisuke Ogasawara, Hui Deng, Andreu Viader, Marc P Baggelaar, Arjen Breman, Hans den Dulk, Adrianus M C H van den Nieuwendijk, Adriann M C H van den Nieuwendijk, Marjolein Soethoudt, Tom van der Wel, Juan Zhou, Herman S Overkleeft, Manuel Sanchez-Alavez, Simone Mori, Simone Mo, William Nguyen, Bruno Conti, Xiaojie Liu, Yao Chen, Qing-Song Liu, Benjamin F Cravatt, Mario van der Stelt. Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition.
Proceedings of the National Academy of Sciences of the United States of America.
2016 Jan; 113(1):26-33. doi:
10.1073/pnas.1522364112
. [PMID: 26668358] - Zoltan Machaty. Signal transduction in mammalian oocytes during fertilization.
Cell and tissue research.
2016 Jan; 363(1):169-183. doi:
10.1007/s00441-015-2291-8
. [PMID: 26453398] - Taha Haffar, Ali Akoumi, Nicolas Bousette. Lipotoxic Palmitate Impairs the Rate of β-Oxidation and Citric Acid Cycle Flux in Rat Neonatal Cardiomyocytes.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2016; 40(5):969-981. doi:
10.1159/000453154
. [PMID: 27941349] - Nami Yamanaka, Shinichiro Saito, Noriko Osaki, Sakura Kamei, Haruo Nakamura, Yoshihisa Katsuragi. Alpha-Linolenic Acid-Enriched Diacylglycerol Oil Suppresses the Postprandial Serum Triglyceride Level-A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.
Journal of nutritional science and vitaminology.
2016; 62(6):402-408. doi:
10.3177/jnsv.62.402
. [PMID: 28202845] - Angela M Smith, Jesse S Harrison, Christopher D Grube, Austin E F Sheppe, Nahoko Sahara, Ryohei Ishii, Osamu Nureki, Hervé Roy. tRNA-dependent alanylation of diacylglycerol and phosphatidylglycerol in Corynebacterium glutamicum.
Molecular microbiology.
2015 Nov; 98(4):681-93. doi:
10.1111/mmi.13150
. [PMID: 26235234] - Tianyi Yuan, Lin Liu, Yongdeng Zhang, Lisi Wei, Shiqun Zhao, Xiaolu Zheng, Xiaoshuai Huang, Jerome Boulanger, Charles Gueudry, Jingze Lu, Lihan Xie, Wen Du, Weijian Zong, Lu Yang, Jean Salamero, Yanmei Liu, Liangyi Chen. Diacylglycerol Guides the Hopping of Clathrin-Coated Pits along Microtubules for Exo-Endocytosis Coupling.
Developmental cell.
2015 Oct; 35(1):120-30. doi:
10.1016/j.devcel.2015.09.004
. [PMID: 26439397] - Zhao Long, Mouming Zhao, Ning Liu, Daolin Liu, Dongxiao Sun-Waterhouse, Qiangzhong Zhao. Physicochemical properties of peanut oil-based diacylglycerol and their derived oil-in-water emulsions stabilized by sodium caseinate.
Food chemistry.
2015 Oct; 184(?):105-13. doi:
10.1016/j.foodchem.2015.03.052
. [PMID: 25872432] - Amarjeet Singh, Nikita Bhatnagar, Amita Pandey, Girdhar K Pandey. Plant phospholipase C family: Regulation and functional role in lipid signaling.
Cell calcium.
2015 Aug; 58(2):139-46. doi:
10.1016/j.ceca.2015.04.003
. [PMID: 25933832] - Han Seok Choi, Su Jin Park, Zang Hee Lee, Sung-Kil Lim. The Effects of a High Fat Diet Containing Diacylglycerol on Bone in C57BL/6J Mice.
Yonsei medical journal.
2015 Jul; 56(4):951-60. doi:
10.3349/ymj.2015.56.4.951
. [PMID: 26069116] - Bradley J Stith. Phospholipase C and D regulation of Src, calcium release and membrane fusion during Xenopus laevis development.
Developmental biology.
2015 May; 401(2):188-205. doi:
10.1016/j.ydbio.2015.02.020
. [PMID: 25748412] - Ahrathy Selathurai, Greg M Kowalski, Micah L Burch, Patricio Sepulveda, Steve Risis, Robert S Lee-Young, Severine Lamon, Peter J Meikle, Amanda J Genders, Sean L McGee, Matthew J Watt, Aaron P Russell, Matthew Frank, Suzanne Jackowski, Mark A Febbraio, Clinton R Bruce. The CDP-Ethanolamine Pathway Regulates Skeletal Muscle Diacylglycerol Content and Mitochondrial Biogenesis without Altering Insulin Sensitivity.
Cell metabolism.
2015 May; 21(5):718-30. doi:
10.1016/j.cmet.2015.04.001
. [PMID: 25955207] - Jin F Qi, Xiang Y Wang, Jung-Ah Shin, Young-Hwa Lee, Young-Seok Jang, Jeung Hee Lee, Soon-Taek Hong, Ki-Teak Lee. Relative oxidative stability of diacylglycerol and triacylglycerol oils.
Journal of food science.
2015 Mar; 80(3):C510-4. doi:
10.1111/1750-3841.12792
. [PMID: 25678328] - Jihyae Ann, Suyoung Yoon, Jisoo Baek, Da Hye Kim, Nancy E Lewin, Colin S Hill, Peter M Blumberg, Jeewoo Lee. Design and synthesis of protein kinase C epsilon selective diacylglycerol lactones (DAG-lactones).
European journal of medicinal chemistry.
2015 Jan; 90(?):332-41. doi:
10.1016/j.ejmech.2014.11.025
. [PMID: 25437619] - Přemysl Pejchar, Jan Martinec. Aluminum ions alter the function of non-specific phospholipase C through the changes in plasma membrane physical properties.
Plant signaling & behavior.
2015; 10(6):e1031938. doi:
10.1080/15592324.2015.1031938
. [PMID: 26024014] - Loay Kh M Hassouneh. [DIACYLGLYCEROL ACCUMULATION IMPAIRS SHORT-TERM ACTIVATION OF PHOSPHOLIPASE D BY THYROXINE IN THE LIVER CELLS].
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994).
2015; 61(2):73-9. doi:
10.15407/fz61.02.073
. [PMID: 26387163] - Wei-Juan Tan, Shi Xiao, Qin-Fang Chen. Potential role of salicylic acid in modulating diacylglycerol homeostasis in response to freezing temperatures in Arabidopsis.
Plant signaling & behavior.
2015; 10(11):e1082698. doi:
10.1080/15592324.2015.1082698
. [PMID: 26340231]