4-Hydroxyphenyl-2-propionic acid (BioDeep_00000003395)

 

Secondary id: BioDeep_00001868761

human metabolite blood metabolite


Metabolite Card


4-Hydroxy-α-methylbenzeneacetic acid

  Formula: C9H10O3 (166.063)
Chinese Names: 2-(4-羟苯基)丙酸
  Spectrum Hits: Top Source Homo sapiens(plant) 7.04%

Molecular Structure

SMILES: CC(C(=O)O)c1ccc(O)cc1
InChI: InChI=1S/C9H10O3/c1-6(9(11)12)7-2-4-8(10)5-3-7/h2-6,10H,1H3,(H,11,12)


Description

4-Hydroxyphenyl-2-propionic acid belongs to the class of organic compounds known as phenylpropanoic acids. Phenylpropanoic acids are compounds with a structure containing a benzene ring conjugated to a propanoic acid. 4-Hydroxyphenyl-2-propionic acid has been detected in multiple biofluids, such as urine and blood (PMID: 20428313). Within the cell, 4-hydroxyphenyl-2-propionic acid is primarily located in the cytoplasm.
A polyphenol metabolite detected in biological fluids [PhenolExplorer]
KEIO_ID H099

Synonyms

30 synonym names

4-Hydroxy-α-methylbenzeneacetic acid; 2-(p-Hydroxyphenyl)-propionic acid; 2-(4-hydroxyphenyl)propanoic acid; Methyl 4-hydroxyphenylacetic acid; 2-(4-hydroxyphenyl)propionic acid; 4-Hydroxyphenyl-2-propionic acid; 2-(4-Hydroxyphenyl)propionate; 4-Hydroxyphenyl-2-propionate; 4-Hydroxyhydratropic acid; 4-hydroxyhydratropate; 2-HPPA CPD; (2RS)-2-(4-Hydroxyphenyl)propionic acid, >=95.0% (qNMR); 2-(4-Hydroxy-phenyl)-propionic acid; 2-(4-hydroxyphenyl)- propionic acid; 2-(4-Hydroxyphenyl)propionic acid, (+/-)-; 2-(4-Hydroxyphenyl)propionicAcid; 2-(4'-Hydroxyphenyl)-propionic acid; 4-HYDROXY-.ALPHA.-METHYLBENZENEACETIC ACID; 4-HYDROXY-ALPHA-METHYLBENZENEACETIC ACID; 4-hydroxy-alpha-methylphenylacetic acid; 4-hydroxyphenyl propanoic acid; 55FH3476SI; BENZENEACETIC ACID, 4-HYDROXY-.ALPHA.-METHYL-; BENZENEACETIC ACID, 4-HYDROXY-ALPHA-METHYL-; Benzeneacetic acid,4-hydroxy-a-methyl-; InChI=1/C9H10O3/c1-6(9(11)12)7-2-4-8(10)5-3-7/h2-6,10H,1H3,(H,11,12); Methyl-4-hydroxyphenylacetic acid; P-HYDROXY HYDRATROPIC ACID; UNII-55FH3476SI; ZHMMPVANGNPCBW-UHFFFAOYSA-



Cross Reference

19 cross reference id

Classification Terms

Related Pathways

Reactome(0)

BioCyc(0)

PlantCyc(0)

Biological Process

0 related biological process reactions.

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 organism taxonomy source information

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



Literature Reference

  • Jin-Lan Wang, Dan Lv, Xiao-Yan Liang, Ming Zhao, Shu-Jun Zhang. [Study on chemical constituents of the Ixeris chinensis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2011 Nov; 34(11):1706-8. doi: . [PMID: 22506392]
  • Junfang Wu, Wenxin Xu, Zhenping Ming, Huifen Dong, Huiru Tang, Yulan Wang. Metabolic changes reveal the development of schistosomiasis in mice. PLoS neglected tropical diseases. 2010 Aug; 4(8):. doi: 10.1371/journal.pntd.0000807. [PMID: 20824219]
  • Annett Braune, Ronald Maul, Nils Helge Schebb, Sabine E Kulling, Michael Blaut. The red clover isoflavone irilone is largely resistant to degradation by the human gut microbiota. Molecular nutrition & food research. 2010 Jul; 54(7):929-38. doi: 10.1002/mnfr.200900233. [PMID: 19998384]
  • Michael Blaut, Lilian Schoefer, Annett Braune. Transformation of flavonoids by intestinal microorganisms. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2003 Mar; 73(2):79-87. doi: 10.1024/0300-9831.73.2.79. [PMID: 12747214]