Alginic acid (BioDeep_00000033700)
human metabolite Endogenous
代谢物信息卡片
6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid
化学式: C12H20O12P2 (418.042998)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1(C(C(OC(C1OC2C(C(C(C(O2)C(=O)O)P)O)O)C(=O)O)OP)O)O
InChI: InChI=1S/C12H20O12P2/c13-1-3(15)12(24-26)22-6(9(17)18)5(1)21-11-4(16)2(14)8(25)7(23-11)10(19)20/h1-8,11-16H,25-26H2,(H,17,18)(H,19,20)
描述信息
Alginic acid, also referred to as algin or alginate, is a hydrophilic, anionic polysaccharide that occurs naturally in brown seaweeds (Laminaria sp., Macrocystis sp., Lessonia sp., and others). It is normally present on the cell walls and in the intracellular spaces of these seaweeds (PMID: 30000910). Alginate forms a viscous gel when mixed with water. It is mainly used as a thickener and stabilizer in foods, pharmaceuticals, and cosmetics. It has a unique ability to absorb and conform to small details making it ideal for creating dental impressions, hands, feet or other small-scale items. Alginate is also used as a thickening agent for soups, ice-cream, cosmetics, jellies, drinks and pharmaceutical preparations, including Gaviscon, which is used to inhibit acid reflux (PMID: 2258131, 231639, 4738939, 6483217, 13224336). Alginate is also used as a pharmaceutical ingredient to treat a variety of health conditions including diabetes, cholesterol, obesity, and digestive tract problems (PMID: 27738945, 6355904, 22054948). Its principal function in biomedical applications is as a hydrogel to treat wound healing and in tissue engineering (PMID: 23020277, 1724711, 31841826, 391598, 19235799, 30959985).
同义名列表
40 个代谢物同义名
6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid; 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylate; Poly(mannuronic acid), sodium salt; Polymannuronic-guluronic acid; Alginic acid, potassium salt; Alginic acid, calcium salt; Alginic acid, sodium salt; Alginic acid, barium salt; Alginic acid, copper salt; Calcium alginate, sodium; Alginate, sodium calcium; sodium calcium alginate; Poly(mannuronic acid); Alginate, potassium; Polymannuronic acid; potassium alginate; Alginate, calcium; Alginate, copper; Alginate, sodium; Calcium alginate; Alginate, barium; Sodium alginate; Copper alginate; Barium alginate; Alginic acid; Kalrostat 2; Kalrostat; Levan gum; Alginates; Xantalgin; Kaltostat; Gum levan; Alginate; Vocoloid; Alloid g; Calginat; Kelacid; Norgine; Sazio; e400
数据库引用编号
6 个数据库交叉引用编号
- PubChem: 131704328
- HMDB: HMDB0029940
- DrugBank: DB13518
- Wikipedia: Alginic acid
- MeSH: Alginates
- foodb: FDB001212
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 9606 - Homo sapiens: -
- 590727 - Sargassum fusiforme: 10.1016/J.IJBIOMAC.2014.05.056
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ting Qiang, Jinyu Wang, Lan Jiang, Ke Xiong. Modulation of hyperglycemia by sodium alginate is associated with changes of serum metabolite and gut microbiota in mice.
Carbohydrate polymers.
2022 Sep; 291(?):119359. doi:
10.1016/j.carbpol.2022.119359. [PMID: 35698318] - Shaoyin Peng, Zhenbei Wang, Fei Qi, Chen Li, Mingyao Xu, Zilong Song, Dezhi Sun, Jun Nan. Novel insights into the interaction reactive components and synergistic fouling mechanisms of ultrafiltration by natural organic matter fractions and kaolin.
Environmental research.
2022 Sep; 212(Pt B):113285. doi:
10.1016/j.envres.2022.113285. [PMID: 35483411] - Maolin Li, Yanbo Liu, Yin Liu, Xin Zhang, Dandan Han, Junbo Gong. pH-driven self-assembly of alcohol-free curcumin-loaded zein-propylene glycol alginate complex nanoparticles.
International journal of biological macromolecules.
2022 Jul; 213(?):1057-1067. doi:
10.1016/j.ijbiomac.2022.06.046. [PMID: 35691429] - Kateřina Štěpánková, Kadir Ozaltin, Jana Pelková, Hana Pištěková, Ilkay Karakurt, Simona Káčerová, Marian Lehocky, Petr Humpolicek, Alenka Vesel, Miran Mozetic. Furcellaran Surface Deposition and Its Potential in Biomedical Applications.
International journal of molecular sciences.
2022 Jul; 23(13):. doi:
10.3390/ijms23137439. [PMID: 35806443] - Haojun Ding, Zixuan Wu, Hao Wang, Zijing Zhou, Yaoming Wei, Kai Tao, Xi Xie, Jin Wu. An ultrastretchable, high-performance, and crosstalk-free proximity and pressure bimodal sensor based on ionic hydrogel fibers for human-machine interfaces.
Materials horizons.
2022 07; 9(7):1935-1946. doi:
10.1039/d2mh00281g. [PMID: 35535758] - Samira Aghamiri, Mojtaba Noofeli, Parvaneh Saffarian, Zahra Salehi Najafabadi, Hamid Reza Goudarzi. Investigating preparation and characterisation of diphtheria toxoid-loaded on sodium alginate nanoparticles.
IET nanobiotechnology.
2022 Jul; 16(5):199-209. doi:
10.1049/nbt2.12088. [PMID: 35610737] - Thanh Lan Chu, Garima Tripathi, Myeongki Park, Sang-Ho Bae, Byong-Taek Lee. In-vitro and in-vivo biocompatibility of dECM-alginate as a promising candidate in cell delivery for kidney regeneration.
International journal of biological macromolecules.
2022 Jun; 211(?):616-625. doi:
10.1016/j.ijbiomac.2022.05.085. [PMID: 35577186] - Lan Huang, Qianhui Zeng, Yudie Zhang, Qing Yin, Xunxian Zhu, Peixi Zhang, Cuifang Wang, Jieqing Liu. Effects of fucoidans and alginates from Sargassum graminifolium on allergic symptoms and intestinal microbiota in mice with OVA-induced food allergy.
Food & function.
2022 Jun; 13(12):6702-6715. doi:
10.1039/d2fo00802e. [PMID: 35660845] - Zhi-Xuan Zhang, Lu Lv, Ai-Hua Shi, Yun-Hao Li, Tian-Ren Wang, Yuan-Hang Guo, Bao-Juan Hu, Xiao-Peng Yan, Jun-Ke Fu, Feng Ma, Hao-Hua Wang, Yi Lv, Yong Zhang. Implementation of sodium alginate-Fe3O4 to localize undiagnosed small pulmonary nodules for surgical management in a preclinical rabbit model.
Scientific reports.
2022 Jun; 12(1):9979. doi:
10.1038/s41598-022-13884-w. [PMID: 35705647] - Chao Zhang, Qi Bao, Huanan Wu, Mingshuai Shao, Xue Wang, Qiyong Xu. Impact of polysaccharide and protein interactions on membrane fouling: Particle deposition and layer formation.
Chemosphere.
2022 Jun; 296(?):134056. doi:
10.1016/j.chemosphere.2022.134056. [PMID: 35192853] - Gopinathan Janarthanan, Jung Hyun Kim, Ingul Kim, Chibum Lee, Eun-Jae Chung, Insup Noh. Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications.
Biofabrication.
2022 05; 14(3):. doi:
10.1088/1758-5090/ac6c4c. [PMID: 35504259] - Philip J Herrod, Brett Doleman, Edward J Hardy, Paul Hardy, Trevor Maloney, John P Williams, Jon N Lund. Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal pilonidal sinus.
The Cochrane database of systematic reviews.
2022 05; 5(?):CD013439. doi:
10.1002/14651858.cd013439.pub2. [PMID: 35593897] - Yingchang Wu, Liu Hong, Xiaofeng Hu, Yunxing Li, Cheng Yang. Efficient Antimicrobial Effect of Alginate-Catechol/Fe2+ Coating on Hydroxyapatite toward Oral Care Application.
ACS applied bio materials.
2022 05; 5(5):2152-2162. doi:
10.1021/acsabm.1c01254. [PMID: 35446545] - Welldone Moyo, Nhamo Chaukura, Machawe M Motsa, Titus A M Msagati, Bhekie B Mamba, Sebastiaan G J Heijman, Thabo T I Nkambule. Modeling the antifouling properties of atomic layer deposition surface-modified ceramic nanofiltration membranes.
Biofouling.
2022 May; 38(5):441-454. doi:
10.1080/08927014.2022.2084613. [PMID: 35686367] - Haiying Cui, Qun Cheng, Changzhu Li, Xiaochen Chen, Lin Lin. Improving packing performance of lily polysaccharide based edible films via combining with sodium alginate and cold plasma treatment.
International journal of biological macromolecules.
2022 May; 206(?):750-758. doi:
10.1016/j.ijbiomac.2022.02.181. [PMID: 35306012] - Raúl Sanz-Horta, Ana Matesanz, José Luis Jorcano, Diego Velasco, Pablo Acedo, Alberto Gallardo, Helmut Reinecke, Carlos Elvira. Preparation and Characterization of Plasma-Derived Fibrin Hydrogels Modified by Alginate di-Aldehyde.
International journal of molecular sciences.
2022 Apr; 23(8):. doi:
10.3390/ijms23084296. [PMID: 35457113] - Bhisham Narayan Singh, Arulkumar Nallakumarasamy, Shivam Sinha, Amit Rastogi, Sarada Prasanna Mallick, Singh Divakar, Pradeep Srivastava. Generation of hybrid tissue engineered construct through embedding autologous chondrocyte loaded platelet rich plasma/alginate based hydrogel in porous scaffold for cartilage regeneration.
International journal of biological macromolecules.
2022 Apr; 203(?):389-405. doi:
10.1016/j.ijbiomac.2022.01.054. [PMID: 35063489] - Itxaso Garcia-Orue, Edorta Santos-Vizcaino, Pello Sanchez, Francisco Borja Gutierrez, Jose Javier Aguirre, Rosa Maria Hernandez, Manoli Igartua. Bioactive and degradable hydrogel based on human platelet-rich plasma fibrin matrix combined with oxidized alginate in a diabetic mice wound healing model.
Materials science & engineering. C, Materials for biological applications.
2022 Apr; 135(?):112695. doi:
10.1016/j.msec.2022.112695. [PMID: 35581070] - Marina Slawinski, Luai R Khoury, Sabita Sharma, Joel Nowitzke, Jennifer H Gutzman, Ionel Popa. Kinetic Method of Producing Pores Inside Protein-Based Biomaterials without Compromising Their Structural Integrity.
ACS biomaterials science & engineering.
2022 03; 8(3):1132-1142. doi:
10.1021/acsbiomaterials.1c01534. [PMID: 35188361] - David Pruß, Harriëtte Oldenhof, Willem F Wolkers, Harald Sieme. Alginate encapsulation of stallion sperm for increasing storage stability.
Animal reproduction science.
2022 Mar; 238(?):106945. doi:
10.1016/j.anireprosci.2022.106945. [PMID: 35184023] - Ying Wang, Tanushree Karmakar, Nilanjan Ghosh, Souvik Basak, Nanda Gopal Sahoo. Targeting mangiferin loaded N-succinyl chitosan-alginate grafted nanoparticles against atherosclerosis - A case study against diabetes mediated hyperlipidemia in rat.
Food chemistry.
2022 Feb; 370(?):131376. doi:
10.1016/j.foodchem.2021.131376. [PMID: 34662793] - Munazza Tamkeen Fatima, Zeyaul Islam, Ejaj Ahmad, Mehboob Hoque, Marriam Yamin. Plasma Bead Entrapped Liposomes as a Potential Drug Delivery System to Combat Fungal Infections.
Molecules (Basel, Switzerland).
2022 Feb; 27(3):. doi:
10.3390/molecules27031105. [PMID: 35164370] - Nihal S Elbialy, Samia F Aboushoushah, Noha Mohamed. Bioinspired synthesis of protein/polysaccharide-decorated folate as a nanocarrier of curcumin to potentiate cancer therapy.
International journal of pharmaceutics.
2022 Feb; 613(?):121420. doi:
10.1016/j.ijpharm.2021.121420. [PMID: 34958897] - Ling Tang, Yi-Hong Chen, Qiong Wang, Xiao-Hui Wang, Qing-Xi Wu, Zhi-Feng Ding. Microencapsulation of functional ovalbumin and bovine serum albumin with polylysine-alginate complex for sustained protein vehicle's development.
Food chemistry.
2022 Jan; 368(?):130902. doi:
10.1016/j.foodchem.2021.130902. [PMID: 34438176] - Saki Maruyama, Yukiko Segawa, Hiroko Hashimoto, Saori Kitamura, Mariko Kimura, Tomoko Osera, Nobutaka Kurihara. Role of alginate in the mechanism by which brown seaweed Saccharina japonica intake alleviates an increase in blood pressure in 2-kidney, 1-clip renovascular hypertensive rats.
Clinical and experimental hypertension (New York, N.Y. : 1993).
2022 Jan; 44(1):72-82. doi:
10.1080/10641963.2021.1991943. [PMID: 34724868] - Vijayaraj Surendran, Narahari N Palei. Formulation and Characterization of Rutin Loaded Chitosan-alginate Nanoparticles: Antidiabetic and Cytotoxicity Studies.
Current drug delivery.
2022; 19(3):379-394. doi:
10.2174/1567201818666211005090656. [PMID: 34636298] - Maha R Gaafar, Salwa T El-Mansoury, Maha M Eissa, Thanaa I Shalaby, Layla K Younis, Hoda A Rashed. Effect of alginate nanoparticles on the immunogenicity of excretory-secretory antigens against acute toxoplasmosis in murine model.
Acta tropica.
2022 Jan; 225(?):106215. doi:
10.1016/j.actatropica.2021.106215. [PMID: 34687647] - Chuang Xu, Meihua Qiao, Xingchen Huo, Zhiwei Liao, Jianguo Su. An Oral Microencapsulated Vaccine Loaded by Sodium Alginate Effectively Enhances Protection Against GCRV Infection in Grass Carp (Ctenopharyngodon idella).
Frontiers in immunology.
2022; 13(?):848958. doi:
10.3389/fimmu.2022.848958. [PMID: 35401526] - Eman M Saleh, Germine M Hamdy, Rasha E Hassan. Neuroprotective effect of sodium alginate against chromium-induced brain damage in rats.
PloS one.
2022; 17(4):e0266898. doi:
10.1371/journal.pone.0266898. [PMID: 35421180] - Ying Yao Chia, T Malathi Theverajah, Yatimah Alias, Sook Mei Khor. Three-dimensional porous calcium alginate fluorescence bead-based immunoassay for highly sensitive early diagnosis of breast cancer.
Analytical and bioanalytical chemistry.
2022 Jan; 414(3):1359-1373. doi:
10.1007/s00216-021-03758-x. [PMID: 34839383] - Yubing Zhang, Song Qin, Yipeng Song, Jingyi Yuan, Shanliang Hu, Min Chen, Lili Li. Alginate Oligosaccharide Alleviated Cisplatin-Induced Kidney Oxidative Stress via Lactobacillus Genus-FAHFAs-Nrf2 Axis in Mice.
Frontiers in immunology.
2022; 13(?):857242. doi:
10.3389/fimmu.2022.857242. [PMID: 35432359] - Shruti Gupta, Upasana Gautam, Shaily Susheilia, Baneet Bansal, Radha Uppal, Radhika Srinivasan. Sodium Alginate versus Plasma Thrombin Cell Blocks in Diagnostic Cytopathology: A Comparative Analysis.
Acta cytologica.
2022; 66(1):72-78. doi:
10.1159/000519336. [PMID: 34718240] - Batoul Alallam, May Kyaw Oo, Wisam Nabeel Ibrahim, Abd Almonem Doolaanea. 3D culture of cancer cells in alginate hydrogel beads as an effective technique for emergency cell storage and transportation in the pandemic era.
Journal of cellular and molecular medicine.
2022 01; 26(1):235-238. doi:
10.1111/jcmm.17078. [PMID: 34873828] - Shan Wang, Wenjing Feng, Jianya Liu, Xufu Wang, Lina Zhong, Chengxiu Lv, Meiping Feng, Nina An, Yongjun Mao. Alginate oligosaccharide alleviates senile osteoporosis via the RANKL-RANK pathway in D-galactose-induced C57BL/6J mice.
Chemical biology & drug design.
2022 01; 99(1):46-55. doi:
10.1111/cbdd.13904. [PMID: 34145772] - Kelly C Freudenberger Catanzaro, Kevin K Lahmers, Irving C Allen, Thomas J Inzana. Alginate microencapsulation of an attenuated O-antigen mutant of Francisella tularensis LVS as a model for a vaccine delivery vehicle.
PloS one.
2022; 17(3):e0259807. doi:
10.1371/journal.pone.0259807. [PMID: 35275912] - Daniel Massana Roquero, Oleh Smutok, Ali Othman, Artem Melman, Evgeny Katz. 'Smart' Delivery of Monoclonal Antibodies from a Magnetic Responsive Microgel Nanocomposite.
ACS applied bio materials.
2021 12; 4(12):8487-8497. doi:
10.1021/acsabm.1c00994. [PMID: 35005932] - Victória Soares Soeiro, Ricardo Silva-Carvalho, Daniela Martins, Pier Parpot, Denise Grotto, Marco Vinicius Chaud, Francisco Miguel Portela da Gama, Angela Faustino Jozala. Alginate-amphotericin B nanocomplexes covered by nanocrystals from bacterial cellulose: physico-chemical characterization and in vitro toxicity.
Scientific reports.
2021 12; 11(1):23944. doi:
10.1038/s41598-021-03264-1. [PMID: 34907234] - Davoodbasha MubarakAli, Minho Lee, Muhammed Allipara Manzoor, Sang-Yul Lee, Jung-Wan Kim. Production of Oligoalginate via Solution Plasma Process and Its Capability of Biological Growth Enhancement.
Applied biochemistry and biotechnology.
2021 Dec; 193(12):4097-4112. doi:
10.1007/s12010-021-03640-7. [PMID: 34449041] - Jihyun Kim, Shwe Phyu Hlaing, Juho Lee, Aruzhan Saparbayeva, Sangsik Kim, Dong Soo Hwang, Eun Hee Lee, In-Soo Yoon, Hwayoung Yun, Min-Soo Kim, Hyung Ryong Moon, Yunjin Jung, Jin-Wook Yoo. Exfoliated bentonite/alginate nanocomposite hydrogel enhances intestinal delivery of probiotics by resistance to gastric pH and on-demand disintegration.
Carbohydrate polymers.
2021 Nov; 272(?):118462. doi:
10.1016/j.carbpol.2021.118462. [PMID: 34420722] - Wenwen Qu, Xuesong Xiang, Cheng Li, Xue Yu, Yajie Li, Qingbin Xing, Yongye Sun. [Effects of intervention of sodium alginate on intakes of foods and macronutrients and situation of serum amino acids in healthy male youths].
Wei sheng yan jiu = Journal of hygiene research.
2021 Nov; 50(6):926-937. doi:
10.19813/j.cnki.weishengyanjiu.2021.06.009. [PMID: 34949318] - Vida Rahmani, Rand Elshereef, Heather Sheardown. Property modelling of lysozyme-crosslinker-alginate complexes using latent variable methods.
Journal of biomedical materials research. Part A.
2021 11; 109(11):2225-2236. doi:
10.1002/jbm.a.37207. [PMID: 33964114] - Tanya Levingstone, Badriah Ali, Cathal Kearney, Nicholas Dunne. Hydroxyapatite sonosensitization of ultrasound-triggered, thermally responsive hydrogels: An on-demand delivery system for bone repair applications.
Journal of biomedical materials research. Part B, Applied biomaterials.
2021 10; 109(10):1622-1633. doi:
10.1002/jbm.b.34820. [PMID: 33600064] - Lara Nigro, Rosa Freitas, Daniela Maggioni, Hady Hamza, Francesca Coppola, Giuseppe Protano, Camilla Della Torre. Coating with polysaccharides influences the surface charge of cerium oxide nanoparticles and their effects to Mytilus galloprovincialis.
NanoImpact.
2021 10; 24(?):100362. doi:
10.1016/j.impact.2021.100362. [PMID: 35559821] - Zhen-Lian Han, Meng Chen, Xiao-Dan Fu, Min Yang, Maria Hrmova, Yuan-Hui Zhao, Hai-Jin Mou. Potassium Alginate Oligosaccharides Alter Gut Microbiota, and Have Potential to Prevent the Development of Hypertension and Heart Failure in Spontaneously Hypertensive Rats.
International journal of molecular sciences.
2021 Sep; 22(18):. doi:
10.3390/ijms22189823. [PMID: 34575987] - Suk-Kyu Koh, Jong-Woo Jeong, Seo-In Choi, Rae Man Kim, Tae-Sung Koo, Kwan Hyung Cho, Kyoung-Won Seo. Pharmacokinetics and diuretic effect of furosemide after single intravenous, oral tablet, and newly developed oral disintegrating film administration in healthy beagle dogs.
BMC veterinary research.
2021 Sep; 17(1):295. doi:
10.1186/s12917-021-02998-4. [PMID: 34488750] - Ning Gao, Mei Li, Liangfei Tian, Avinash J Patil, B V V S Pavan Kumar, Stephen Mann. Chemical-mediated translocation in protocell-based microactuators.
Nature chemistry.
2021 09; 13(9):868-879. doi:
10.1038/s41557-021-00728-9. [PMID: 34168327] - Ji Ji, Guang Chen, Zitong Liu, Lili Li, Jiugang Yuan, Ping Wang, Bo Xu, Xuerong Fan. Preparation of PEG-modified wool keratin/sodium alginate porous scaffolds with elasticity recovery and good biocompatibility.
Journal of biomedical materials research. Part B, Applied biomaterials.
2021 09; 109(9):1303-1312. doi:
10.1002/jbm.b.34791. [PMID: 33421269] - Chao Zou, Ling Huang, Donghui Li, Yu Ma, Yixiang Liu, Yanbo Wang, Min-Jie Cao, Guang-Ming Liu, Lechang Sun. Assembling cyanidin-3-O-glucoside by using low-viscosity alginate to improve its in vitro bioaccessibility and in vivo bioavailability.
Food chemistry.
2021 Sep; 355(?):129681. doi:
10.1016/j.foodchem.2021.129681. [PMID: 33799247] - Ángel Serrano-Aroca, María Ferrandis-Montesinos, Ruibing Wang. Antiviral Properties of Alginate-Based Biomaterials: Promising Antiviral Agents against SARS-CoV-2.
ACS applied bio materials.
2021 08; 4(8):5897-5907. doi:
10.1021/acsabm.1c00523. [PMID: 35006918] - Thomas Geuens, Floor A A Ruiter, Anika Schumacher, Francis L C Morgan, Timo Rademakers, Loes E Wiersma, Cathelijne W van den Berg, Ton J Rabelink, Matthew B Baker, Vanessa L S LaPointe. Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition.
Biomaterials.
2021 08; 275(?):120976. doi:
10.1016/j.biomaterials.2021.120976. [PMID: 34198162] - Mina Popović, Marijana Stojanović, Zlate Veličković, Ana Kovačević, Radmila Miljković, Nemanja Mirković, Aleksandar Marinković. Characterization of potential probiotic strain, L. reuteri B2, and its microencapsulation using alginate-based biopolymers.
International journal of biological macromolecules.
2021 Jul; 183(?):423-434. doi:
10.1016/j.ijbiomac.2021.04.177. [PMID: 33932415] - Shadpour Mallakpour, Elham Azadi, Chaudhery Mustansar Hussain. Chitosan, alginate, hyaluronic acid, gums, and β-glucan as potent adjuvants and vaccine delivery systems for viral threats including SARS-CoV-2: A review.
International journal of biological macromolecules.
2021 Jul; 182(?):1931-1940. doi:
10.1016/j.ijbiomac.2021.05.155. [PMID: 34048834] - Daojiu Zhang, Shaoyu Wang, Mingchun Wang, Zijian Wu, Steve W Cui, Hao Wang, Biao Wang. Stability and bioaccessibility improvement of capsorubin using bovine serum albumin-dextran-gallic acid and sodium alginate.
International journal of biological macromolecules.
2021 Jul; 182(?):1362-1370. doi:
10.1016/j.ijbiomac.2021.05.033. [PMID: 33965493] - Lilia Gutierrez, Teresa Lechuga, Xelhua Marcos, Perla García-Guzmán, Carlos Gutrierrez, Hector Sumano. Comparative bioavailability of enrofloxacin in dogs when concealed in noncommercial morsels, either as tablet or as enrofloxacin-alginate dried beads.
Journal of veterinary pharmacology and therapeutics.
2021 Jul; 44(4):522-532. doi:
10.1111/jvp.12925. [PMID: 33112449] - Juan Huang, Jinli Huang, Yao Li, Yilu Wang, Fahe Wang, Xia Qiu, Xvliang Liu, Huajun Li. Sodium Alginate Modulates Immunity, Intestinal Mucosal Barrier Function, and Gut Microbiota in Cyclophosphamide-Induced Immunosuppressed BALB/c Mice.
Journal of agricultural and food chemistry.
2021 Jun; 69(25):7064-7073. doi:
10.1021/acs.jafc.1c02294. [PMID: 34152142] - Hiraku Onishi, Osamu Sakata. Preparation and evaluation of fast-dissolving films of etilefrine hydrochloride for practical buccal dosing.
Pharmaceutical development and technology.
2021 Jun; 26(5):610-616. doi:
10.1080/10837450.2021.1904260. [PMID: 33736577] - Julius Sundermann, Sarah Oehmichen, Steffen Sydow, Laura Burmeister, Bastian Quaas, Robert Hänsch, Ursula Rinas, Andrea Hoffmann, Henning Menzel, Heike Bunjes. Varying the sustained release of BMP-2 from chitosan nanogel-functionalized polycaprolactone fiber mats by different polycaprolactone surface modifications.
Journal of biomedical materials research. Part A.
2021 05; 109(5):600-614. doi:
10.1002/jbm.a.37045. [PMID: 32608183] - Thomas Distler, Christian Polley, Fukun Shi, Dominik Schneidereit, Mark D Ashton, Oliver Friedrich, Jürgen F Kolb, John G Hardy, Rainer Detsch, Hermann Seitz, Aldo R Boccaccini. Electrically Conductive and 3D-Printable Oxidized Alginate-Gelatin Polypyrrole:PSS Hydrogels for Tissue Engineering.
Advanced healthcare materials.
2021 05; 10(9):e2001876. doi:
10.1002/adhm.202001876. [PMID: 33711199] - Żaneta Król-Kilińska, Dominika Kulig, Ihar Yelkin, Anna Zimoch-Korzycka, Łukasz Bobak, Andrzej Jarmoluk. The Effect of Using Micro-Clustered Water as a Polymer Medium.
International journal of molecular sciences.
2021 Apr; 22(9):. doi:
10.3390/ijms22094730. [PMID: 33946988] - Rebecca Marie Dewhurst, Elisa Molinari, John A Sayer. Cell preservation methods and its application to studying rare disease.
Molecular and cellular probes.
2021 04; 56(?):101694. doi:
10.1016/j.mcp.2021.101694. [PMID: 33429040] - A Said Ismail, Gregory R Goodwin, J Rafael Castrejon-Pita, Alastair J Noyce, Helena S Azevedo. A novel capsule-based smell test fabricated via coaxial dripping.
Journal of the Royal Society, Interface.
2021 04; 18(177):20210039. doi:
10.1098/rsif.2021.0039. [PMID: 33906383] - Qiu Huang, Fukun He, Jiafei Yu, Jing Zhang, Xiangyun Du, Qing Li, Gefei Wang, Ziyi Yu, Su Chen. Microfluidic spinning-induced heterotypic bead-on-string fibers for dual-cargo release and wound healing.
Journal of materials chemistry. B.
2021 03; 9(11):2727-2735. doi:
10.1039/d0tb02305a. [PMID: 33683250] - Deepa Thomas, Neethu Mathew, Megha S Nath. Starch modified alginate nanoparticles for drug delivery application.
International journal of biological macromolecules.
2021 Mar; 173(?):277-284. doi:
10.1016/j.ijbiomac.2020.12.227. [PMID: 33453259] - Katarzyna Szurkowska, Paulina Kazimierczak, Joanna Kolmas. Mg,Si-Co-Substituted Hydroxyapatite/Alginate Composite Beads Loaded with Raloxifene for Potential Use in Bone Tissue Regeneration.
International journal of molecular sciences.
2021 Mar; 22(6):. doi:
10.3390/ijms22062933. [PMID: 33805785] - Suji Ryu, Seungyeop Park, Ha Yeon Lee, Hyungjun Lee, Cheong-Weon Cho, Jong-Suep Baek. Biodegradable Nanoparticles-Loaded PLGA Microcapsule for the Enhanced Encapsulation Efficiency and Controlled Release of Hydrophilic Drug.
International journal of molecular sciences.
2021 Mar; 22(6):. doi:
10.3390/ijms22062792. [PMID: 33801871] - Rania Taymour, David Kilian, Tilman Ahlfeld, Michael Gelinsky, Anja Lode. 3D bioprinting of hepatocytes: core-shell structured co-cultures with fibroblasts for enhanced functionality.
Scientific reports.
2021 03; 11(1):5130. doi:
10.1038/s41598-021-84384-6. [PMID: 33664366] - Fayyaz Ahamed, Mark Van Criekinge, Zhen J Wang, John Kurhanewicz, Peder Larson, Renuka Sriram. Modeling hyperpolarized lactate signal dynamics in cells, patient-derived tissue slice cultures and murine models.
NMR in biomedicine.
2021 03; 34(3):e4467. doi:
10.1002/nbm.4467. [PMID: 33415771] - Yumei Pu, Shiqi Hu, Yongfeng Chen, Qian Zhang, Chengwan Xia, Han Deng, Yuxin Wang, Qingang Hu. Thymoquinone loaded calcium alginate and polyvinyl alcohol carrier inhibits the 7,12-dimethylbenz[a]anthracene-induced hamster oral cancer via the down-regulation of PI3K/AKT/mTOR signaling pathways.
Environmental toxicology.
2021 Mar; 36(3):339-351. doi:
10.1002/tox.23040. [PMID: 33068063] - Chung-Yi Lee, Adhimoorthy Prasannan, Varghese Lincy, Subash Vetri Selvi, Shen Ming Chen, Po-Da Hong. Highly exfoliated functionalized MoS2 with sodium alginate-polydopamine conjugates for electrochemical sensing of cardio-selective β-blocker by voltammetric methods.
Mikrochimica acta.
2021 03; 188(3):103. doi:
10.1007/s00604-021-04717-0. [PMID: 33646401] - Li Ji, Fenglun Zhang, Liwei Zhu, Jianxin Jiang. An in-situ fabrication of bamboo bacterial cellulose/sodium alginate nanocomposite hydrogels as carrier materials for controlled protein drug delivery.
International journal of biological macromolecules.
2021 Feb; 170(?):459-468. doi:
10.1016/j.ijbiomac.2020.12.139. [PMID: 33359254] - Veeresh Toragall, Vallikanan Baskaran. Chitosan-sodium alginate-fatty acid nanocarrier system: Lutein bioavailability, absorption pharmacokinetics in diabetic rat and protection of retinal cells against H2O2 induced oxidative stress in vitro.
Carbohydrate polymers.
2021 Feb; 254(?):117409. doi:
10.1016/j.carbpol.2020.117409. [PMID: 33357895] - Fan Lu, Yeling Yang, Yucheng Liu, Fubing Wang, Xinghu Ji, Zhike He. Point-of-care testing (POCT) of patients with a high concentration of uric acid by using alginate hydrogel microspheres embedded with CdZnTeS QDs and urate oxidase (Alg@QDs-UOx MSs).
The Analyst.
2021 Feb; 146(3):949-955. doi:
10.1039/d0an02029j. [PMID: 33245089] - Truc Cong Ho, Jin-Seok Park, Sung-Yeoul Kim, Hoyeol Lee, Ju-Sop Lim, Shin-Jun Kim, Mi-Hee Choi, Seung Yun Nam, Byung-Soo Chun. Influences of Molecular Weights on Physicochemical and Biological Properties of Collagen-Alginate Scaffolds.
Marine drugs.
2021 Feb; 19(2):. doi:
10.3390/md19020085. [PMID: 33540717] - Ali Salari, Kambiz Roshanaei, Bahram Rasoulian, Javad Khalili Fard. Carvacrol loaded beta cyclodextrin-alginate-chitosan based nanoflowers attenuates renal toxicity induced by malathion and parathion: A comparative toxicity.
Pesticide biochemistry and physiology.
2021 Feb; 172(?):104747. doi:
10.1016/j.pestbp.2020.104747. [PMID: 33518056] - Taskeen Niaz, Anwesha Sarkar, Alan Mackie, Muhammad Imran. Impact of albumin corona on mucoadhesion and antimicrobial activity of carvacrol loaded chitosan nano-delivery systems under simulated gastro-intestinal conditions.
International journal of biological macromolecules.
2021 Feb; 169(?):171-182. doi:
10.1016/j.ijbiomac.2020.12.085. [PMID: 33340623] - Fa-Quan Zhao, Gui-Fang Wang, Dong Xu, Hai-Yun Zhang, Yuan-Lu Cui, Qiang-Song Wang. Glycyrrhizin mediated liver-targeted alginate nanogels delivers quercetin to relieve acute liver failure.
International journal of biological macromolecules.
2021 Jan; 168(?):93-104. doi:
10.1016/j.ijbiomac.2020.11.204. [PMID: 33278444] - M Marounek, Z Volek, T Taubner, M Czauderna. Metabolic Effects of a Hydrophobic Alginate Derivative and Tetrahydrolipstatin in Rats Fed a Diet Supplemented with Palm Fat and Cholesterol.
Folia biologica.
2021; 67(4):143-149. doi:
. [PMID: 35151239] - Maimuna Majimbi, Emily Brook, Peter Galettis, Edward Eden, Hani Al-Salami, Armin Mooranian, Hesham Al-Sallami, Virginie Lam, John C L Mamo, Ryusuke Takechi. Sodium alginate microencapsulation improves the short-term oral bioavailability of cannabidiol when administered with deoxycholic acid.
PloS one.
2021; 16(6):e0243858. doi:
10.1371/journal.pone.0243858. [PMID: 34138862] - Jiuxin Qu, Zhao Cai, Yumei Liu, Xiangke Duan, Shuhong Han, Jihong Liu, Yuao Zhu, Zhaofang Jiang, Yingdan Zhang, Chao Zhuo, Yang Liu, Yingxia Liu, Lei Liu, Liang Yang. Persistent Bacterial Coinfection of a COVID-19 Patient Caused by a Genetically Adapted Pseudomonas aeruginosa Chronic Colonizer.
Frontiers in cellular and infection microbiology.
2021; 11(?):641920. doi:
10.3389/fcimb.2021.641920. [PMID: 33816347] - Mahtab Haghighat, Alireza Iranbakhsh, Javad Baharara, Mostafa Ebadi, Fattah Sotoodehnejadnematalahi. Effect of β-carotene on the differentiation potential of ciliary epithelium-derived MSCs isolated from mouse eyes on alginate-based scaffolds.
Experimental eye research.
2021 01; 202(?):108346. doi:
10.1016/j.exer.2020.108346. [PMID: 33147471] - Mohammad A A Al-Najjar, Tamara Athamneh, Reem AbuTayeh, Iman Basheti, Claudia Leopold, Pavel Gurikov, Irina Smirnova. Evaluation of the orally administered calcium alginate aerogel on the changes of gut microbiota and hepatic and renal function of Wistar rats.
PloS one.
2021; 16(4):e0247633. doi:
10.1371/journal.pone.0247633. [PMID: 33909615] - Abbas Rami, Fatemeh Kazemi-Lomedasht, Ali Mirjalili, Mojtaba Noofeli, Fereshteh Shahcheraghi, Naser M Dounighi. Outer Membrane Vesicles of Bordetella pertussis Encapsulated into Sodium Alginate Nanoparticles as Novel Vaccine Delivery System.
Current pharmaceutical design.
2021; 27(42):4341-4354. doi:
10.2174/1381612827666210907154715. [PMID: 34493192] - Pinyapach Dungkokkruad, Shunsuke Tomita, Youhei Hiromori, Keishi Ishida, Daisuke Matsumaru, Kyoko Mekada, Hisamitsu Nagase, Keiichi Tanaka, Tsuyoshi Nakanishi. Alginate-coated activated charcoal enhances fecal excretion of 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice, with fewer side effects than uncoated one.
The Journal of toxicological sciences.
2021; 46(8):379-389. doi:
10.2131/jts.46.379. [PMID: 34334559] - Hui Pan, Wenjing Feng, Ming Chen, Hong Luan, Yi Hu, Xiaoyue Zheng, Shan Wang, Yongjun Mao. Alginate Oligosaccharide Ameliorates D-Galactose-Induced Kidney Aging in Mice through Activation of the Nrf2 Signaling Pathway.
BioMed research international.
2021; 2021(?):6623328. doi:
10.1155/2021/6623328. [PMID: 33506023] - Mattia Pasqua, Ulysse Pereira, Claire de Lartigue, Jonathan Nicolas, Pascale Vigneron, Quentin Dermigny, Cécile Legallais. Preclinical characterization of alginate-poly-L-lysine encapsulated HepaRG for extracorporeal liver supply.
Biotechnology and bioengineering.
2021 01; 118(1):453-464. doi:
10.1002/bit.27583. [PMID: 32997339] - Mou Zhou, Fang Lin, Wendan Li, Linying Shi, Yanhui Li, Guiqiu Shan. Development of nanosilver doped carboxymethyl chitosan-polyamideamine alginate composite dressing for wound treatment.
International journal of biological macromolecules.
2021 Jan; 166(?):1335-1351. doi:
10.1016/j.ijbiomac.2020.11.014. [PMID: 33171183] - E M Mahmoud, M Sayed, Abeer M El-Kady, Hamada Elsayed, S M Naga. In vitro and in vivo study of naturally derived alginate/hydroxyapatite bio composite scaffolds.
International journal of biological macromolecules.
2020 Dec; 165(Pt A):1346-1360. doi:
10.1016/j.ijbiomac.2020.10.014. [PMID: 33038401] - Vahid Lohrasbi, Milad Abdi, Arezoo Asadi, Mahdi Rohani, Maryam Esghaei, Malihe Talebi, Nour Amirmozafari. The effect of improved formulation of chitosan-alginate microcapsules of Bifidobacteria on serum lipid profiles in mice.
Microbial pathogenesis.
2020 Dec; 149(?):104585. doi:
10.1016/j.micpath.2020.104585. [PMID: 33075520] - Elena De Angelis, Stefano Grolli, Roberta Saleri, Virna Conti, Melania Andrani, Martina Berardi, Valeria Cavalli, Benedetta Passeri, Francesca Ravanetti, Paolo Borghetti. Platelet lysate reduces the chondrocyte dedifferentiation during in vitro expansion: Implications for cartilage tissue engineering.
Research in veterinary science.
2020 Dec; 133(?):98-105. doi:
10.1016/j.rvsc.2020.08.017. [PMID: 32961475] - Noha Nafee, Abd El Rahman Ameen, Osama Y Abdallah. Patient-Friendly, Olfactory-Targeted, Stimuli-Responsive Hydrogels for Cerebral Degenerative Disorders Ensured > 400\% Brain Targeting Efficiency in Rats.
AAPS PharmSciTech.
2020 Nov; 22(1):6. doi:
10.1208/s12249-020-01872-0. [PMID: 33222021] - Veeresh Toragall, Naveen Jayapala, Muthukumar S P, Baskaran Vallikanan. Biodegradable chitosan-sodium alginate-oleic acid nanocarrier promotes bioavailability and target delivery of lutein in rat model with no toxicity.
Food chemistry.
2020 Nov; 330(?):127195. doi:
10.1016/j.foodchem.2020.127195. [PMID: 32585586] - Osamu Sakata, Hiraku Onishi. Preparation of orally fast-dissolving tablets of etilefrine hydrochloride to achieve efficient absorption.
Pharmaceutical development and technology.
2020 Nov; 25(9):1162-1167. doi:
10.1080/10837450.2020.1794000. [PMID: 32644855] - Le Xu, Jian Che, Yongping Xu, Yan Chen, Yuan Li, Bilal Murtaza, Lili Wang, Meixia Zhang, Xiaoyu Li. Oral administration of microencapsulated egg yolk immunoglobulin (IgY) in turbot (Scophthalmus maximus) to combat against Edwardsiella tarda 2CDM001 infections.
Fish & shellfish immunology.
2020 Nov; 106(?):609-620. doi:
10.1016/j.fsi.2020.08.024. [PMID: 32795594] - Lars Christophersen, Franziska Angelika Schwartz, Christian Johann Lerche, Trine Svanekjær, Kasper Nørskov Kragh, Anne Sofie Laulund, Kim Thomsen, Kaj-Åge Henneberg, Thomas Sams, Niels Høiby, Claus Moser. In vivo demonstration of Pseudomonas aeruginosa biofilms as independent pharmacological microcompartments.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.
2020 11; 19(6):996-1003. doi:
10.1016/j.jcf.2020.01.009. [PMID: 32067957] - Ovidiu Tița, Maria Adelina Constantinescu, Mihaela Adriana Tița, Cecilia Georgescu. Use of Yoghurt Enhanced with Volatile Plant Oils Encapsulated in Sodium Alginate to Increase the Human Body's Immunity in the Present Fight Against Stress.
International journal of environmental research and public health.
2020 10; 17(20):. doi:
10.3390/ijerph17207588. [PMID: 33086508] - R Jose Varghese, Sundararajan Parani, V R Remya, Rodney Maluleke, Sabu Thomas, Oluwatobi S Oluwafemi. Sodium alginate passivated CuInS2/ZnS QDs encapsulated in the mesoporous channels of amine modified SBA 15 with excellent photostability and biocompatibility.
International journal of biological macromolecules.
2020 Oct; 161(?):1470-1476. doi:
10.1016/j.ijbiomac.2020.07.240. [PMID: 32745549] - Werner E G Müller, Emad Tolba, Shunfeng Wang, Meik Neufurth, Ingo Lieberwirth, Maximilian Ackermann, Heinz C Schröder, Xiaohong Wang. Nanoparticle-directed and ionically forced polyphosphate coacervation: a versatile and reversible core-shell system for drug delivery.
Scientific reports.
2020 10; 10(1):17147. doi:
10.1038/s41598-020-73100-5. [PMID: 33051468] - Yaya Li, Christoph Rehbock, Milen Nachev, Jacqueline Stamm, Bernd Sures, Andreas Blaeser, Stephan Barcikowski. Matrix-specific mechanism of Fe ion release from laser-generated 3D-printable nanoparticle-polymer composites and their protein adsorption properties.
Nanotechnology.
2020 Oct; 31(40):405703. doi:
10.1088/1361-6528/ab94da. [PMID: 32434157] - Tessa R Flood, Stefano Montanari, Marley Wicks, Jack Blanchard, Holly Sharp, Lee Taylor, Matthew R Kuennen, Ben J Lee. Addition of pectin-alginate to a carbohydrate beverage does not maintain gastrointestinal barrier function during exercise in hot-humid conditions better than carbohydrate ingestion alone.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.
2020 Oct; 45(10):1145-1155. doi:
10.1139/apnm-2020-0118. [PMID: 32365303]