Quinoline-3-carboxamide (BioDeep_00000332377)
代谢物信息卡片
化学式: C10H8N2O (172.06365979999998)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C2C(=C1)C=C(C=N2)C(=O)N
InChI: InChI=1S/C10H8N2O/c11-10(13)8-5-7-3-1-2-4-9(7)12-6-8/h1-6H,(H2,11,13)
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Juliana Draibe, Ruth J Pepper, Alan D Salama. Treatment with Quinoline-3-carboxamide does not successfully prevent immune-mediated glomerulonephritis in mice.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia.
2016 Nov; 36(6):687-693. doi:
10.1016/j.nefro.2016.03.012. [PMID: 27174662] - Alexandru Schiopu, Ovidiu S Cotoi. S100A8 and S100A9: DAMPs at the crossroads between innate immunity, traditional risk factors, and cardiovascular disease.
Mediators of inflammation.
2013; 2013(?):828354. doi:
10.1155/2013/828354. [PMID: 24453429] - Karin Jennbacken, Karin Welén, Anders Olsson, Bengt Axelsson, Marie Törngren, Jan-Erik Damber, Tomas Leanderson. Inhibition of metastasis in a castration resistant prostate cancer model by the quinoline-3-carboxamide tasquinimod (ABR-215050).
The Prostate.
2012 Jun; 72(8):913-24. doi:
10.1002/pros.21495. [PMID: 22287276] - Anders A Bengtsson, Gunnar Sturfelt, Christian Lood, Lars Rönnblom, Ronald F van Vollenhoven, Bengt Axelsson, Birgitta Sparre, Helén Tuvesson, Marie Wallén Ohman, Tomas Leanderson. Pharmacokinetics, tolerability, and preliminary efficacy of paquinimod (ABR-215757), a new quinoline-3-carboxamide derivative: studies in lupus-prone mice and a multicenter, randomized, double-blind, placebo-controlled, repeat-dose, dose-ranging study in patients with systemic lupus erythematosus.
Arthritis and rheumatism.
2012 May; 64(5):1579-88. doi:
10.1002/art.33493. [PMID: 22131101] - Christian Lood, Martin Stenström, Helena Tydén, Birgitta Gullstrand, Eva Källberg, Tomas Leanderson, Lennart Truedsson, Gunnar Sturfelt, Fredrik Ivars, Anders A Bengtsson. Protein synthesis of the pro-inflammatory S100A8/A9 complex in plasmacytoid dendritic cells and cell surface S100A8/A9 on leukocyte subpopulations in systemic lupus erythematosus.
Arthritis research & therapy.
2011 Apr; 13(2):R60. doi:
10.1186/ar3314. [PMID: 21492422] - Susan L Dalrymple, Robin E Becker, John T Isaacs. The quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts.
The Prostate.
2007 May; 67(7):790-7. doi:
10.1002/pros.20573. [PMID: 17373719]