Protosappanin B (BioDeep_00000332214)
Main id: BioDeep_00000230898
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C16H16O6 (304.0946836)
中文名称: 巴西苏木素, 分析对照品
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C2=CC(=C(C=C2C3=C(C=C(C=C3)O)OCC1(CO)O)O)O
InChI: InChI=1S/C16H16O6/c17-7-16(21)6-9-3-13(19)14(20)5-12(9)11-2-1-10(18)4-15(11)22-8-16/h1-5,17-21H,6-8H2
描述信息
Protosappanin B is a phenolic compound extracted from Caesalpinia sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2].
Protosappanin B is a phenolic compound extracted from Caesalpinia sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2].
同义名列表
2 个代谢物同义名
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代谢反应
0 个相关的代谢反应过程信息。
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BioCyc(0)
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Plant Reactome(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xiaodan Zheng, Jingqiu Chen, Nanquan Rao, Chun Yang, Juan Liu, Jun Zhang, Yanhong Li. The Effect of an Extract of Sappanwood, Protosappanin A and Protosappanin B on Osteogenesis in Periodontitis.
Frontiers in bioscience (Landmark edition).
2023 08; 28(8):172. doi:
10.31083/j.fbl2808172. [PMID: 37664926] - Yueting Li, Wensha Meng, Li Yuan, Li Jiang, Zuying Zhou, Mingyan Chi, Zipeng Gong, Xue Ma, Yong Huang, Lin Zheng. Identification of Protosappanoside D from Caesalpinia decapetala and Evaluation of Its Pharmacokinetic, Metabolism and Pharmacological Activity.
Molecules (Basel, Switzerland).
2022 Sep; 27(18):. doi:
10.3390/molecules27186090. [PMID: 36144821] - Wei-Ying Chen, Guang-Yan Liang, Zuo-Liang Zheng, Yun-Shan Wu, Fang-Fang Xu, Bo Liu, De-An Guo. UPLC-ESI-Q-TOF/MS Based Metabolic Profiling of Protosappanin B in Rat Plasma, Bile, Feces, Urine and Intestinal Bacteria Samples.
Current drug metabolism.
2021; 22(6):491-499. doi:
10.2174/1389200222666210219123846. [PMID: 33605854] - Wei-Ying Chen, Xian-Zhen Zhou, Li-Lan Wu, Yun-Shan Wu, Shu-Mei Wang, Bo Liu, De-An Guo. A UPLC/MS/MS method for determination of protosappanin B in rat plasma and its application of a pharmacokinetic and bioavailability study.
Biomedical chromatography : BMC.
2017 Jul; 31(7):. doi:
10.1002/bmc.3919. [PMID: 27976417] - Xihua Yang, Liansheng Ren, Shengwan Zhang, Lili Zhao, Jing Wang. Antitumor Effects of Purified Protosappanin B Extracted From Lignum Sappan.
Integrative cancer therapies.
2016 Mar; 15(1):87-95. doi:
10.1177/1534735415588929. [PMID: 26036624]