2,4-Di-tert-butylphenol (BioDeep_00000033111)

 

Secondary id: BioDeep_00000270985

human metabolite PANOMIX_OTCML-2023 Endogenous Industrial Pollutants


代谢物信息卡片


1-Hydroxy-2,4-di-tert-butylbenzene

  化学式: C14H22O (206.1671)
中文名称: 2,4-二叔丁基苯酚, 2,4-二叔丁基酚
  谱图信息: 最多检出来源 Viridiplantae(plant) 70.36%

Reviewed

Last reviewed on 2024-09-14.

Cite this Page

2,4-Di-tert-butylphenol. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/2,4-di-tert-butylphenol (retrieved 2025-05-04) (BioDeep RN: BioDeep_00000033111). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC(C)(C)C1=CC(=C(C=C1)O)C(C)(C)C
InChI: InChI=1S/C14H22O/c1-13(2,3)10-7-8-12(15)11(9-10)14(4,5)6/h7-9,15H,1-6H3


描述信息

2,4-Di-tert-butylphenol, also known as 2,4-DTBP, belongs to the class of organic compounds known as phenylpropanes. These are organic compounds containing a phenylpropane moiety. 2,4-Di-tert-butylphenol is an extremely weak basic (essentially neutral) compound (based on its pKa). 2,4-Di-tert-butylphenol is a synthetic phenolic antioxidant (SPA). SPAs are a family of chemicals used widely in foods, polymers, and cosmetics as radical trapping agents to slow down degradation due to oxidation. Given their widespread use, human exposure is unavoidable and there is public concern regarding environmental contamination by these chemicals. 2,4-Di-tert-butylphenol was detected at extremely high concentrations in human urine (PMID: 31265952).
2,4-Di-tert-butylphenol is an endogenous metabolite.
2,4-Di-tert-butylphenol is an endogenous metabolite.

同义名列表

65 个代谢物同义名

1-Hydroxy-2,4-di-tert-butylbenzene; 2,4-Bis(1,1-dimethylethyl)-phenol; 2,4-Bis(1,1-dimethylethyl)phenol; 2,4-Di-tert-butylhydroxybenzene; 2,4-Bis(tert-butyl)phenol; 2,4-Di-tert-butyl-phenol; 2,4-Di-tert-butylphenol; 2,4-Tert-butylphenol; 2,4-Di-t-butylphenol; 2,4-DTBP; DBP; UGW; UNII-FOB94G6HZT; variabilone; 2,4-DtBP; WLN: 1X1&1&R BQ CX1&1&1; 2,4-Di-tert-butylphenol; ,4-Di-tert-butylphenol; (2S)-N-[(1S)-2-[[(1S)-2-[[(1S)-2-[[(1S)-2-[[2-[[(1S)-1-[[(1S)-4-amino-1-[(2S)-2-[(2-amino-2-oxo-ethyl)carbamoyl]pyrrolidine-1-carbonyl]-4-oxo-butyl]carbamoyl]-3-methyl-butyl]amino]-2-oxo-ethyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]amino]-1-(hydro; 1-Hydroxy-2, 4-di-tert-butylbenzene; 1Hydroxy2,4ditertbutylbenzene; 1ST8731; 1ST8731-1000; 2,4-Bis(1,1'-dimethylethyl)phenol; 2,4-di-t-butyl-phenol; 2,4-di-tert-butyl phenol; 2,4-Di-tert-butylphenol (Standard); 2,4-Di-tert-butylphenol 100 microg/mL in Acetonitrile; 2,4-Di-tert-butylphenol Solution in Acetonitrile, 1000?g/mL; 2,4-Di-tert-butylphenol Solution in Acetonitrile, 1000mug/mL; 2,4-Di-tert-butylphenol, 99%; 2,4-Di-tert.-butylphenol; 2,4-di-tert.butylphenol; 2,4-di-tertbutyl phenol; 2,4-di-tertbutylphenol; 2,4-di~{tert}-butylphenol; 2,4-ditert-butyl phenol; 2,4-ditert-butyl-phenol; 2,4-ditert-butylphenol; 2,4-Ditert-butylphenol (ACD/Name 4.0); 2,4-ditertbutylphenol; 2,4-ditertiary-butyl phenol; 2,4-ditertiarybutylphenol; 2,4Bis(1,1dimethylethyl)phenol; 2,4Bis(1,1dimetiletil)fenolo; 2,4Bis(tertbutyl)phenol; 2,4di-tert-butylphenol; 2,4Ditertbutylhydroxybenzene; 4-(2-methylbutan-2-yl)-2-(prop-2-en-1-yl)phenol; AGIDOL 10; Antioxidant No 33; Antioxidant No. 33; CAS-96-76-4; FOB94G6HZT; Phenol, 2,4-bis(1,1-dimethylethyl)-; Phenol, 2,4-di-tert-butyl-; Phenol, 2,4-di(1,1-dimethylethyl)-; Phenol, 2,4bis(1,1dimethylethyl); Phenol, 2,4di(1,1dimethylethyl); Phenol, 2,4ditertbutyl; Phenol,2,4-Bis(1,1-dimethylethyl); Phenol,4-bis(1,1-dimethylethyl)-; Phenol,4-di-tert-butyl-; Tox21_202320; Tox21_300114



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Yongmeng Yang, Chen Yan, Aifeng Li, Jiangbing Qiu, Wenhui Yan, Hui Dang. Effects of the plastic additive 2,4-di-tert-butylphenol on intestinal microbiota of zebrafish. Journal of hazardous materials. 2024 May; 469(?):133987. doi: 10.1016/j.jhazmat.2024.133987. [PMID: 38461668]
  • Shujie Ma, Han Zhao, Sijia Liu, Ci Tian, Ming Gao, Yizhen Wang, Jingao Dong, Lihui Zhang. 2,4-Di-tert-butylphenol and 7-hydroxy-3-(2-methylpropyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione: two natural products from Serratia marcescens Ha1 and their herbicidal activities. Pest management science. 2024 Mar; 80(3):1016-1025. doi: 10.1002/ps.7833. [PMID: 37831548]
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  • Pragya Paramita Pal, Ahil Sajeli Begum, S Ameer Basha, Hiroshi Araya, Yoshinori Fujimoto. New natural pro-inflammatory cytokines (TNF-α, IL-6 and IL-1β) and iNOS inhibitors identified from Penicillium polonicum through in vitro and in vivo studies. International immunopharmacology. 2023 Apr; 117(?):109940. doi: 10.1016/j.intimp.2023.109940. [PMID: 37012863]
  • Pragya Paramita Pal, Sajeli A Begum, Ameer S Basha, Hiroshi Araya, Yoshinori Fujimoto. A New Lignan (Polonilignan) and Inhibitors of Nitric Oxide Production from Penicillium polonicum, an Endophytic Fungi of Piper nigrum. Chemistry & biodiversity. 2023 Mar; 20(3):e202200840. doi: 10.1002/cbdv.202200840. [PMID: 36662670]
  • Xiao-Min Ren, Richard C Chang, Yikai Huang, Angélica Amorim Amato, Coralie Carivenc, Marina Grimaldi, Yun Kuo, Patrick Balaguer, William Bourguet, Bruce Blumberg. 2,4-Di-tert-butylphenol Induces Adipogenesis in Human Mesenchymal Stem Cells by Activating Retinoid X Receptors. Endocrinology. 2023 02; 164(4):. doi: 10.1210/endocr/bqad021. [PMID: 36750942]
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  • Runzeng Liu, Scott A Mabury. Unexpectedly high concentrations of 2,4-di-tert-butylphenol in human urine. Environmental pollution (Barking, Essex : 1987). 2019 Sep; 252(Pt B):1423-1428. doi: 10.1016/j.envpol.2019.06.077. [PMID: 31265952]
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  • Soo Jung Choi, Jae Kyeom Kim, Hye Kyung Kim, Keith Harris, Chang-Ju Kim, Gwi Gun Park, Cheung-Seog Park, Dong-Hoon Shin. 2,4-Di-tert-butylphenol from sweet potato protects against oxidative stress in PC12 cells and in mice. Journal of medicinal food. 2013 Nov; 16(11):977-83. doi: 10.1089/jmf.2012.2739. [PMID: 24074359]
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