Hydroxytriamterene sulfate (BioDeep_00000330772)

   


代谢物信息卡片


p-hydroxy triamterene sulfate

化学式: C12H11N7O4S (349.05932060000004)
中文名称: 4-羟基-2,4,7-三氨基-6-苯基蝶啶磺酸钠盐
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1C2=NC3=C(N=C(N=C3N=C2N)N)N)OS(=O)(=O)O
InChI: InChI=1S/C12H11N7O4S/c13-9-7(5-1-3-6(4-2-5)23-24(20,21)22)16-8-10(14)18-12(15)19-11(8)17-9/h1-4H,(H,20,21,22)(H6,13,14,15,17,18,19)

描述信息

同义名列表

2 个代谢物同义名

p-hydroxy triamterene sulfate; Hydroxytriamterene sulfate



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

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Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Stephen C Pelly, Sameshnee Govender, Manuel A Fernandes, Hans-Günther Schmalz, Charles B de Koning. Stereoselective syntheses of the 2-Isopropenyl-2,3-dihydrobenzofuran nucleus: potential chiral building blocks for the syntheses of tremetone, hydroxytremetone, and rotenone. The Journal of organic chemistry. 2007 Apr; 72(8):2857-64. doi: 10.1021/jo062447h. [PMID: 17375958]
  • Christian Horstkötter, Susan Kober, Hildegard Spahn-Langguth, Ernst Mutschler, Gottfried Blaschke. Determination of triamterene and its main metabolite hydroxytriamterene sulfate in human urine by capillary electrophoresis using ultraviolet absorbance and laser-induced fluorescence detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2002 Mar; 769(1):107-17. doi: 10.1016/s1570-0232(02)00002-8. [PMID: 11936683]
  • W Möhrke, H Knauf, E Mutschler. Pharmacokinetics and pharmacodynamics of triamterene and hydrochlorothiazide and their combination in healthy volunteers. International journal of clinical pharmacology and therapeutics. 1997 Oct; 35(10):447-52. doi: NULL. [PMID: 9352394]
  • K D Völger. [Animal experimental and human pharmacologic studies with phase-II metabolites of triamterene]. Arzneimittel-Forschung. 1991 May; 41(5):499-506. doi: NULL. [PMID: 1898420]
  • M R Muirhead, A A Somogyi, C Lloyd, F Bochner. Deconjugation of p-hydroxytriamterene sulphate in the rat. Xenobiotica; the fate of foreign compounds in biological systems. 1989 Jun; 19(6):655-60. doi: 10.3109/00498258909042302. [PMID: 2763574]
  • M T Dao, J P Villeneuve. Kinetics and dynamics of triamterene at steady-state in patients with cirrhosis. Clinical and investigative medicine. Medecine clinique et experimentale. 1988 Feb; 11(1):6-9. doi: NULL. [PMID: 3365882]
  • R L Williams, M D Thornhill, R A Upton, C Blume, T S Clark, E Lin, L Z Benet. Absorption and disposition of two combination formulations of hydrochlorothiazide and triamterene: influence of age and renal function. Clinical pharmacology and therapeutics. 1986 Aug; 40(2):226-32. doi: 10.1038/clpt.1986.167. [PMID: 3731685]
  • F Sörgel, B Ettinger, L Z Benet. The true composition of kidney stones passed during triamterene therapy. The Journal of urology. 1985 Nov; 134(5):871-3. doi: 10.1016/s0022-5347(17)47497-0. [PMID: 4057369]
  • B Ettinger. Excretion of triamterene and its metabolite in triamterene stone patients. Journal of clinical pharmacology. 1985 Jul; 25(5):365-8. doi: 10.1002/j.1552-4604.1985.tb02856.x. [PMID: 4031113]
  • E Mutschler, H J Gilfrich, H Knauf, W Möhrke, K D Völger. Pharmacokinetics of triamterene. Clinical and experimental hypertension. Part A, Theory and practice. 1983; 5(2):249-69. doi: 10.3109/10641968309048825. [PMID: 6831748]
  • D J White, G H Nancollas. Triamterene and renal stone formation. The Journal of urology. 1982 Mar; 127(3):593-7. doi: 10.1016/s0022-5347(17)53919-1. [PMID: 7062445]
  • G Leilich, H Knauf, E Mutschler, K D Völger. Influence of triamterene and hydroxytriamterene sulfuric acid ester on diuresis and saluresis in rats after oral and intravenous application. Arzneimittel-Forschung. 1980; 30(6):949-53. doi: NULL. [PMID: 7191270]