Endrin (BioDeep_00000003283)
Secondary id: BioDeep_00001028323
human metabolite Endogenous Volatile Flavor Compounds
代谢物信息卡片
化学式: C12H8Cl6O (377.8706298)
中文名称: 狄氏剂, 异狄氏剂
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: ClC1=C(Cl)C2(Cl)C3C4CC(C5OC45)C3C1(Cl)C2(Cl)Cl
InChI: InChI=1S/C12H8Cl6O/c13-8-9(14)11(16)5-3-1-2(6-7(3)19-6)4(5)10(8,15)12(11,17)18/h2-7H,1H2
描述信息
Endrin has been found as a contaminant throughout the environment, including foodstuffs, fish, human milk, etc
Has been found as a contaminant throughout the environment, including foodstuffs, fish, human milk, etc.
同义名列表
31 个代谢物同义名
3,4,5,6,9,9-hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-Dimethanonaph[2,3-b]oxirene, 9ci; 3,4,5,6,13,13-hexachloro-10-oxapentacyclo[6.3.1.1³,⁶.0²,⁷.0⁹,¹¹]tridec-4-ene; hexachloroepoxyoctahydro-endo, endo-Dimethanonaphthalene; hexachloroepoxyoctahydro-endo,endo-Dimethanonaphthalene; hexachloroepoxyoctahydro-endo,endo-Dimethanonapthalene; Experimental insecticide 269; Endrin and metabolites; SD 3419 Illoxol; Endrin mixture; Endrin isomer; Endrin 20 ec; Compound 269; Stardrin 20; Compd. 269; Latka 269; ent 17251; Hexadrin; dieldrin; Stardrin; Endricol; Mendrin; Nendrin; Endrine; Oktanex; OMS 197; Endrex; endrin; EN 57; Endrin; Dieldrin; Dieldrin
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:34696
- KEGG: C13718
- PubChem: 3048
- HMDB: HMDB0031211
- Wikipedia: Endrin
- foodb: FDB003234
- chemspider: 2940
- CAS: 72-20-8
- CAS: 60-57-1
- PMhub: MS000008686
- PubChem: 586307
- NIKKAJI: J236.021G
- KEGG: C18124
- PubChem: 96024341
- KNApSAcK: 81526
- KNApSAcK: 34696
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
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BioMed research international.
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Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
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Marine pollution bulletin.
2014 Sep; 86(1-2):266-273. doi:
10.1016/j.marpolbul.2014.07.007
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Chemosphere.
2011 May; 83(7):891-6. doi:
10.1016/j.chemosphere.2011.02.073
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Obesity (Silver Spring, Md.).
2010 Jul; 18(7):1283-8. doi:
10.1038/oby.2009.419
. [PMID: 19927138] - Luis D Boada, Pedro C Lara, Eva E Alvarez-León, Antonio Losada, Manuel L Zumbado, Jose M Limiñana-Cañal, Rosa Apolinario, Lluis Serra-Majem, Octavio P Luzardo. Serum levels of insulin-like growth factor-I in relation to organochlorine pesticides exposure.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
2007 Dec; 17(6):506-11. doi:
10.1016/j.ghir.2007.05.004
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Gan to kagaku ryoho. Cancer & chemotherapy.
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"
. [PMID: 17212088] - Debasis Bagchi, Jaya Balmoori, Manashi Bagchi, Xumein Ye, Casey B Williams, Sidney J Stohs. Comparative effects of TCDD, endrin, naphthalene and chromium (VI) on oxidative stress and tissue damage in the liver and brain tissues of mice.
Toxicology.
2002 Jun; 175(1-3):73-82. doi:
10.1016/s0300-483x(02)00062-8
. [PMID: 12049837] - E van Wyk, H Bouwman, H van der Bank, G H Verdoorn, D Hofmann. Persistent organochlorine pesticides detected in blood and tissue samples of vultures from different localities in South Africa.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2001 Jul; 129(3):243-64. doi:
10.1016/s1532-0456(01)90201-7
. [PMID: 11461840] - D Bagchi, J Balmoori, M Bagchi, X Ye, C B Williams, S J Stohs. Role of p53 tumor suppressor gene in the toxicity of TCDD, endrin, naphthalene, and chromium (VI) in liver and brain tissues of mice.
Free radical biology & medicine.
2000 Mar; 28(6):895-903. doi:
10.1016/s0891-5849(00)00173-8
. [PMID: 10802220] - T H Wu, T R Rainwater, S G Platt, S T McMurry, T A Anderson. Organochlorine contaminants in Morelet's crocodile (Crocodylus moreletii) eggs from Belize.
Chemosphere.
2000 Mar; 40(6):671-8. doi:
10.1016/s0045-6535(99)00456-7
. [PMID: 10705543] - E A Hassoun, D Bagchi, S J Stohs. TCDD endrin and lindane induced increases in lipid metabolites in maternal sera and amniotic fluids of pregnant C57BL/6J and DBA/2J mice.
Research communications in molecular pathology and pharmacology.
1996 Nov; 94(2):157-69. doi:
NULL
. [PMID: 8987113] - E A Hassoun, S J Stohs. TCDD, endrin and lindane induced oxidative stress in fetal and placental tissues of C57BL/6J and DBA/2J mice.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.
1996 Sep; 115(1):11-8. doi:
10.1016/s0742-8413(96)00116-8
. [PMID: 8983165] - D Bagchi, G Bhattacharya, S J Stohs. In vitro and in vivo induction of heat shock (stress) protein (Hsp) gene expression by selected pesticides.
Toxicology.
1996 Aug; 112(1):57-68. doi:
10.1016/0300-483x(96)03350-1
. [PMID: 8792849] - D Bagchi, M Bagchi, E A Hassoun, S J Stohs. In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides.
Toxicology.
1995 Dec; 104(1-3):129-40. doi:
10.1016/0300-483x(95)03156-a
. [PMID: 8560491] - M Bagchi, S Ghosh, D Bagchi, E Hassoun, S J Stohs. Protective effects of lazaroid U74389F (16-desmethyl tirilazad) on endrin-induced lipid peroxidation and DNA damage in brain and liver and regional distribution of catalase activity in rat brain.
Free radical biology & medicine.
1995 Dec; 19(6):867-72. doi:
10.1016/0891-5849(95)00088-f
. [PMID: 8582661] - D Bagchi, E A Hassoun, M Bagchi, S J Stohs. Protective effects of antioxidants against endrin-induced hepatic lipid peroxidation, DNA damage, and excretion of urinary lipid metabolites.
Free radical biology & medicine.
1993 Aug; 15(2):217-22. doi:
10.1016/0891-5849(93)90062-y
. [PMID: 8375695] - M Bagchi, E Hassoun, P Akubue, D Bagchi, S J Stohs. Comparative effects of endrin on hepatic lipid peroxidation and DNA damage, and nitric oxide production by peritoneal macrophages from C57BL/6J and DBA/2 mice.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.
1993 Jul; 105(3):525-9. doi:
10.1016/0742-8413(93)90096-4
. [PMID: 7900971] - E Hassoun, M Bagchi, D Bagchi, S J Stohs. Comparative studies on lipid peroxidation and DNA-single strand breaks induced by lindane, DDT, chlordane and endrin in rats.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.
1993 Mar; 104(3):427-31. doi:
10.1016/0742-8413(93)90013-b
. [PMID: 7689940] - M Bagchi, E A Hassoun, D Bagchi, S J Stohs. Production of reactive oxygen species by peritoneal macrophages and hepatic mitochondria and microsomes from endrin-treated rats.
Free radical biology & medicine.
1993 Feb; 14(2):149-55. doi:
10.1016/0891-5849(93)90005-f
. [PMID: 8381102] - M Bagchi, S J Stohs. In vitro induction of reactive oxygen species by 2,3,7,8-tetrachlorodibenzo-p-dioxin, endrin, and lindane in rat peritoneal macrophages, and hepatic mitochondria and microsomes.
Free radical biology & medicine.
1993 Jan; 14(1):11-8. doi:
10.1016/0891-5849(93)90504-n
. [PMID: 7681024] - D Bagchi, M Bagchi, E Hassoun, S J Stohs. Endrin-induced urinary excretion of formaldehyde, acetaldehyde, malondialdehyde and acetone in rats.
Toxicology.
1992 Oct; 75(1):81-9. doi:
10.1016/0300-483x(92)90128-2
. [PMID: 1455427] - M Bagchi, E A Hassoun, D Bagchi, S J Stohs. Endrin-induced increases in hepatic lipid peroxidation, membrane microviscosity, and DNA damage in rats.
Archives of environmental contamination and toxicology.
1992 Jul; 23(1):1-5. doi:
10.1007/bf00225988
. [PMID: 1637188] - M A Shara, P H Dickson, D Bagchi, S J Stohs. Excretion of formaldehyde, malondialdehyde, acetaldehyde and acetone in the urine of rats in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin, paraquat, endrin and carbon tetrachloride.
Journal of chromatography.
1992 May; 576(2):221-33. doi:
10.1016/0378-4347(92)80196-w
. [PMID: 1400710] - M Q Hassan, I T Numan, N al-Nasiri, S J Stohs. Endrin-induced histopathological changes and lipid peroxidation in livers and kidneys of rats, mice, guinea pigs and hamsters.
Toxicologic pathology.
1991; 19(2):108-14. doi:
10.1177/019262339101900204
. [PMID: 1771364] - I T Numan, M Q Hassan, S J Stohs. Protective effects of antioxidants against endrin-induced lipid peroxidation, glutathione depletion, and lethality in rats.
Archives of environmental contamination and toxicology.
1990 May; 19(3):302-6. doi:
10.1007/bf01054969
. [PMID: 2353831] - I T Numan, M Q Hassan, S J Stohs. Endrin-induced depletion of glutathione and inhibition of glutathione peroxidase activity in rats.
General pharmacology.
1990; 21(5):625-8. doi:
10.1016/0306-3623(90)91008-f
. [PMID: 2276583] - H W Hogmire, J E Weaver, J L Brooks. Survey for pesticides in wells associated with apple and peach orchards in West Virginia.
Bulletin of environmental contamination and toxicology.
1990 Jan; 44(1):81-6. doi:
10.1007/bf01702365
. [PMID: 2306542] - M P Quick, I C Shaw, P A Manser. A surprising case of endrin poisoning in dogs.
Journal - Forensic Science Society.
1989 Sep; 29(5):331-8. doi:
10.1016/s0015-7368(89)73273-4
. [PMID: 2584949] - R Kummer, N J van Sittert. Field studies on health effects from the application of two organophosphorus insecticide formulations by hand-held ULV to cotton.
Toxicology letters.
1986 Oct; 33(1-3):7-24. doi:
10.1016/0378-4274(86)90067-6
. [PMID: 3022432] - R A Young, H M Mehendale. Effect of endrin and endrin derivatives on hepatobiliary function and carbon tetrachloride-induced hepatotoxicity in male and female rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
1986 Aug; 24(8):863-8. doi:
10.1016/0278-6915(86)90078-5
. [PMID: 3781435] - A Ilahi, N Amin, A S Hashmi, M Nawaz, N Rahman. Incidence of endrin residues in cucumber and its effects on the biological system of rats.
JPMA. The Journal of the Pakistan Medical Association.
1986 Aug; 36(8):209-11. doi:
NULL
. [PMID: 3097344] - P H Ribbens. Mortality study of industrial workers exposed to aldrin, dieldrin and endrin.
International archives of occupational and environmental health.
1985; 56(2):75-9. doi:
10.1007/bf00379378
. [PMID: 4055072] - A M Hilmy, H K Badawi, M B Shabana. Physiological mechanism of toxic action of DDT and endrin in two euryhaline freshwater fishes, Anguilla vulgaris and Mugil cephalus.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.
1983; 76(1):173-9. doi:
10.1016/0742-8413(83)90060-9
. [PMID: 6139246] - H Singh, T P Singh. Short-term effect of two pesticides on the survival, ovarian 32P uptake and gonadotrophic potency in a freshwater catfish, Heteropneustes fossilis (Blouch).
The Journal of endocrinology.
1980 May; 85(2):193-9. doi:
10.1677/joe.0.0850193
. [PMID: 7400707] - M K Baldwin, D H Hutson. Analysis of human urine for a metabolite of endrin by chemical oxidation and gas-liquid chromatography as an indicator of exposure to endrin.
The Analyst.
1980 Jan; 105(1246):60-5. doi:
10.1039/an9800500060
. [PMID: 7386890] - S K Sharma, L D Chaturvedi, K V Sastry. Acute endrin toxicity on oxidases of Ophiocephalus punctatus (Bloch).
Bulletin of environmental contamination and toxicology.
1979 Sep; 23(1-2):153-7. doi:
10.1007/bf01769934
. [PMID: 497419] - M D Reuber. Carcinogenicity of endrin.
The Science of the total environment.
1979 Jun; 72(2):101-35. doi:
10.1016/0048-9697(79)90112-8
. [PMID: 382353] - K V Sastry, S K Sharma. Endrin toxicosis on few enzymes in liver and kidney of Channa punctatus (Bloch).
Bulletin of environmental contamination and toxicology.
1979 May; 22(1-2):4-8. doi:
10.1007/bf02026898
. [PMID: 223699] - S K Sharma, K V Sastry. Alteration in enzymes activities in liver and kidney of Channa punctatus exposed to endrin.
Bulletin of environmental contamination and toxicology.
1979 May; 22(1-2):17-20. doi:
10.1007/bf02026900
. [PMID: 223697] - K V Sastry, S K Sharma. In vivo effect of endrin on three phosphatases in kidney and liver of the fish Ophiocephalus punctatus.
Bulletin of environmental contamination and toxicology.
1979 Jan; 21(1-2):185-9. doi:
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. [PMID: 221062] - A F Afifi, M E Abdulla. Effect of spraying developed shoot system with insecticide 'endrin' on rhizosphere mycoflora of both okra and lupins.
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite naturwissenschaftliche Abteilung: Mikrobiologie der Landwirtschaft der Technologie und des Umweltschutzes.
1979; 134(7):587-93. doi:
10.1016/s0323-6056(79)80107-x
. [PMID: 549396] - K V Sastry, S K Sharma. The effect of in vivo exposure of endrin on the activities of acid, alkaline and glucose-6-phosphatases in liver and kidney of Ophiocephalus (Channa) punctatus.
Bulletin of environmental contamination and toxicology.
1978 Oct; 20(4):456-60. doi:
10.1007/bf01683549
. [PMID: 214192] - S S Pawar, M S Kachole. Hepatic and renal microsomal electron transport reactions in endrin treated female guinea pigs.
Bulletin of environmental contamination and toxicology.
1978 Aug; 20(2):199-205. doi:
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Environmental research.
1978 Jul; 16(1-3):373-82. doi:
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Bulletin of environmental contamination and toxicology.
1977 Sep; 18(3):355-60. doi:
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Journal of agricultural and food chemistry.
1977 Mar; 25(2):393-8. doi:
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Bulletin of environmental contamination and toxicology.
1976 Sep; 16(3):253-60. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
1976 Jul; 6(7):425-9. doi:
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Journal - Association of Official Analytical Chemists.
1976 Jan; 59(1):224-5. doi:
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. [PMID: 2580] - V J Petrella, J P Fox, R E Webb. Endrin metabolism in endrin-susceptible and -resistant strains of pine mice.
Toxicology and applied pharmacology.
1975 Nov; 34(2):283-91. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
1975 Nov; 5(11):697-714. doi:
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Journal - Association of Official Analytical Chemists.
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Xenobiotica; the fate of foreign compounds in biological systems.
1975 Aug; 5(8):485-500. doi:
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The Journal of pharmacology and experimental therapeutics.
1974 Jan; 188(1):265-76. doi:
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. [PMID: 4358438] - S Kacew, R L Singhal. The influence of p,p'-DDT, alpha-chlordane, heptachlor and endrin on hepatic and renal carbohydrate metabolism and cyclic AMP-adenyl cyclase system.
Life sciences.
1973 Nov; 13(10):1363-71. doi:
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DTW. Deutsche tierarztliche Wochenschrift.
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. [PMID: 4113379] - D A REINS, D D HOLMES, L B HINSHAW. ACUTE AND CHRONIC EFFECTS OF THE INSECTICIDE ENDRIN ON RENAL FUNCTION AND RENAL HEMODYNAMICS.
Canadian journal of physiology and pharmacology.
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