11-Hydroxyeicosatetraenoate glyceryl ester (BioDeep_00000032695)

   

human metabolite Endogenous


代谢物信息卡片


1,3-Dihydroxypropan-2-yl (5Z,8Z,11S,12E,14Z)-11-hydroxyicosa-5,8,12,14-tetraenoic acid

化学式: C23H38O5 (394.2719098)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCC=CC=CC(CC=CCC=CCCCC(=O)OC(CO)CO)O
InChI: InChI=1S/C23H38O5/c1-2-3-4-5-7-10-13-16-21(26)17-14-11-8-6-9-12-15-18-23(27)28-22(19-24)20-25/h6-7,9-11,13-14,16,21-22,24-26H,2-5,8,12,15,17-20H2,1H3/b9-6-,10-7-,14-11-,16-13+/t21-/m1/s1

描述信息

11(R)-HETE is produced from arachidonic acid by both COX-1 and COX-2 (cyclooxygenases). Using a model of intestinal epithelial cells that express the COX-2 permanently, 11(R)-HETE is produced upon stimulation. However, 11(R)-HETE is not detected in intact cells. Endothelial cells release several factors which influence vascular tone, leukocyte function and platelet aggregation; 11(R)-HETE is one of these factors. (PMID: 15964853, 8555273) [HMDB]
11(R)-HETE is produced from arachidonic acid by both COX-1 and COX-2 (cyclooxygenases). Using a model of intestinal epithelial cells that express the COX-2 permanently, 11(R)-HETE is produced upon stimulation. However, 11(R)-HETE is not detected in intact cells. Endothelial cells release several factors which influence vascular tone, leukocyte function and platelet aggregation; 11(R)-HETE is one of these factors. (PMID: 15964853, 8555273).

同义名列表

8 个代谢物同义名

1,3-Dihydroxypropan-2-yl (5Z,8Z,11S,12E,14Z)-11-hydroxyicosa-5,8,12,14-tetraenoic acid; 1,3-dihydroxypropan-2-yl (5Z,8Z,11S,12E,14Z)-11-hydroxyicosa-5,8,12,14-tetraenoate; (11S)-Hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl-2-glyceryl ester; (5Z,8Z,12E,14Z)-11S-Hydroxyeicosatetraenoyl-2-glyceryl ester; 2-[(11S)-Hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-glycerol; 11-Hydroxyeicosatetraenoic acid glyceryl ester; 11-Hydroxyeicosatetraenoate glyceryl ester; 11-HETE-g



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

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INOH(0)

PlantCyc(0)

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1 个相关的物种来源信息

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