(-)-Epigallocatechin sulfate (BioDeep_00000032670)

   

human metabolite Endogenous blood metabolite


代谢物信息卡片


(2S,3S)-8-Hydroxy-3-(sulphooxy)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-6-olic acid

化学式: C15H13O10S- (385.0229)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 85.71%

分子结构信息

SMILES: C1C(C(OC2=C1C=C(C=C2O)O)C3=CC(=C(C(=C3)O)O)O)OS(=O)(=O)[O-]
InChI: InChI=1S/C15H14O10S/c16-8-1-6-4-12(25-26(21,22)23)15(24-14(6)11(19)5-8)7-2-9(17)13(20)10(18)3-7/h1-3,5,12,15-20H,4H2,(H,21,22,23)/p-1/t12-,15-/m0/s1

描述信息

Epigallocatechin sulfate is the sulfated form of epigallocatechin, wherein the sulfate group is attached to the O-3 position. Sulfation is a phase II biotransformation reaction that involves a sulfotransferase enzyme catalyzing the transfer of a sulfo group from a donor cosubstrate, usually 3-phosphoadenosine-5-phosphosulfate (PAPS), to a substrate molecules hydroxyl group (in this case epigallogatechin). Sulfation is involved in a variety of biological processes, including detoxification, hormone regulation, molecular recognition, cell signaling, and viral entry into cells. Epigallocatechin (EGC) is a flavan-3-ol, which are derivatives of flavans that possess a 2-phenyl-3,4-dihydro-2H-chromen-3-ol skeleton. EGC is one of the antioxidant chemicals found in many fruits and teas. This compound possesses an epimer, found notably in green tea, called "gallocatechin" (GC) (PMID: 30917581), with the gallate residue being in an isomeric trans position. Other sources of gallocatechin are bananas, persimmon, and pomegranate. This compound had been shown to have moderate affinity to the human cannabinoid receptor, which may contribute to the health benefits found by consuming green tea.

同义名列表

9 个代谢物同义名

(2S,3S)-8-Hydroxy-3-(sulphooxy)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-6-olic acid; (2S,3S)-8-Hydroxy-3-(sulfooxy)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-6-olic acid; (2S,3S)-8-Hydroxy-3-(sulphooxy)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-6-olate; (2S,3S)-6,8-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl sulfate; (-)-Epigallocatechin sulphuric acid; (-)-Epigallocatechin sulfuric acid; (-)-Epigallocatechin sulphate; (-)-Epigallocatechin sulfate; EACSul



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代谢反应

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1 个相关的物种来源信息

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  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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