Riccardin D (BioDeep_00000323738)
代谢物信息卡片
化学式: C28H24O4 (424.1675)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: Oc1ccc2cc1Oc1ccc(cc1)CCc1cccc(O)c1-c1ccc(cc1O)CC2
InChI:
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Hong-Zhuo Shi, Wen-Qiang Chang, Ming Zhang, Hong-Xiang Lou. Two natural molecules preferentially inhibit azole-resistant Candida albicans with MDR1 hyperactivation.
Chinese journal of natural medicines.
2019 Mar; 17(3):209-217. doi:
10.1016/s1875-5364(19)30023-8
. [PMID: 30910057] - Huiping Liu, Guoning Li, Bin Zhang, Deqing Sun, Jing Wu, Fang Chen, Feng Kong, Yun Luan, Wen Jiang, Rongmei Wang, Xia Xue. Suppression of the NF‑κB signaling pathway in colon cancer cells by the natural compound Riccardin D from Dumortierahirsute.
Molecular medicine reports.
2018 04; 17(4):5837-5843. doi:
10.3892/mmr.2018.8617
. [PMID: 29484409] - Yoshinori Asakawa, Agnieszka Ludwiczuk. Chemical Constituents of Bryophytes: Structures and Biological Activity.
Journal of natural products.
2018 03; 81(3):641-660. doi:
10.1021/acs.jnatprod.6b01046
. [PMID: 29019405] - X Ling, J Xing, J-Z Zhang, W-F Chen, X Zan, F-Y Du, X-X Li, H Yao, H-X Lou. The absorption, distribution, metabolism and excretion of Riccardin D in rats.
Drug research.
2013 Mar; 63(3):159-64. doi:
10.1055/s-0033-1334895
. [PMID: 23430703] - Xia Xue, De-Fu Sun, Cui-Cui Sun, Hui-Ping Liu, Bin Yue, Cui-Rong Zhao, Hong-Xiang Lou, Xian-Jun Qu. Inhibitory effect of riccardin D on growth of human non-small cell lung cancer: in vitro and in vivo studies.
Lung cancer (Amsterdam, Netherlands).
2012 Jun; 76(3):300-8. doi:
10.1016/j.lungcan.2011.12.013
. [PMID: 22261315] - Xia Xue, Xian-Jun Qu, Zu-Hua Gao, Cui-Cui Sun, Hui-Ping Liu, Cui-Rong Zhao, Yan-Na Cheng, Hong-Xiang Lou. Riccardin D, a novel macrocyclic bisbibenzyl, induces apoptosis of human leukemia cells by targeting DNA topoisomerase II.
Investigational new drugs.
2012 Feb; 30(1):212-22. doi:
10.1007/s10637-010-9554-8
. [PMID: 20924640] - Hui-Ping Liu, Zu-Hua Gao, Shu-Xiang Cui, De-Fu Sun, Yan Wang, Cui-Rong Zhao, Hong-Xiang Lou, Xian-Jun Qu. Inhibition of intestinal adenoma formation in APC(Min/+) mice by Riccardin D, a natural product derived from liverwort plant Dumortiera hirsuta.
PloS one.
2012; 7(3):e33243. doi:
10.1371/journal.pone.0033243
. [PMID: 22432006] - Cui-cui Sun, Yu-sheng Zhang, Xia Xue, Yan-na Cheng, Hui-ping Liu, Cui-rong Zhao, Hong-xiang Lou, Xian-jun Qu. Inhibition of angiogenesis involves in anticancer activity of riccardin D, a macrocyclic bisbibenzyl, in human lung carcinoma.
European journal of pharmacology.
2011 Sep; 667(1-3):136-43. doi:
10.1016/j.ejphar.2011.06.013
. [PMID: 21704029]