3-Hydroxyaspartic acid (BioDeep_00000003203)

 

Secondary id: BioDeep_00001869687


代谢物信息卡片


D-Aspartic acid,3-hydroxy-, (3S)-rel-

化学式: C4H7NO5 (149.0324212)
中文名称: (2R,3S)-2-氨基-3-羟基琥珀酸, (2S,3R)-2-氨基-3-羟基琥珀酸, DL-苏-beta-羟基天冬氨酸, 3-羟基天冬氨酸, ERYTHRO-Β-羟基-L-天冬氨酸
谱图信息: 最多检出来源 Viridiplantae(plant) 3.66%

分子结构信息

SMILES: C(C(C(=O)O)O)(C(=O)O)N
InChI: InChI=1S/C4H7NO5/c5-1(3(7)8)2(6)4(9)10/h1-2,6H,5H2,(H,7,8)(H,9,10)

描述信息

A hydroxy-amino acid that is aspartic acid in which one of the methylene hydrogens has been replaced by a hydroxy group.
D018377 - Neurotransmitter Agents > D018846 - Excitatory Amino Acids
KEIO_ID H086

同义名列表

11 个代谢物同义名

D-Aspartic acid,3-hydroxy-, (3S)-rel-; DL-Threo-beta-Hydroxyaspartic Acid; D-Aspartic acid,3-hydroxy-, (3S)-; 3-Hydroxyaspartic acid; 2-amino-3-hydroxy-butanedioic acid; erythro-3-Hydroxy-Ls-aspartic acid; erythro-3-Hydroxy-L-aspartic acid; erythro-3-Hydroxy-Ls-aspartate; (3R)-3-hydroxy-L-aspartic acid; erythro-3-Hydroxy-L-aspartate; threo-b-Hydroxyaspartate



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mingxia Liu, Lixia Chen, Xiangjun Li, Jinghua Meng, Yu Bai, Huwei Liu. Separation and determination of 3-hydroxyaspartate by online concentration capillary electrophoresis/laser-induced fluorescence with microwave-assisted derivatization. Journal of separation science. 2021 Oct; 44(19):3646-3653. doi: 10.1002/jssc.202100398. [PMID: 34350710]
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  • Claudio Frank, Anna Maria Giammarioli, Loredana Falzano, Carla Fiorentini, Stefano Rufini. Glutamate-induced calcium increase in myotubes depends on up-regulation of a sodium-dependent transporter. FEBS letters. 2002 Sep; 527(1-3):269-73. doi: 10.1016/s0014-5793(02)03200-3. [PMID: 12220672]
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  • T S Otis, M P Kavanaugh, C E Jahr. Postsynaptic glutamate transport at the climbing fiber-Purkinje cell synapse. Science (New York, N.Y.). 1997 Sep; 277(5331):1515-8. doi: 10.1126/science.277.5331.1515. [PMID: 9278516]
  • M Demestre, M Boutelle, M Fillenz. Stimulated release of lactate in freely moving rats is dependent on the uptake of glutamate. The Journal of physiology. 1997 Mar; 499 ( Pt 3)(?):825-32. doi: 10.1113/jphysiol.1997.sp021971. [PMID: 9130175]
  • M P Langford, M E Berg, J H Mack, J P Ganley, T C Welbourne. Inhibition of glutamate uptake causes an acute increase in aqueous humor protein. Experimental eye research. 1997 Feb; 64(2):157-65. doi: 10.1006/exer.1996.0180. [PMID: 9176048]
  • T C Welbourne, D Chevalier, X Mu. Glutamate transport modulation of paracellular permeability across LLC-PK1-F+ monolayers. The American journal of physiology. 1996 Nov; 271(5 Pt 1):E889-95. doi: 10.1152/ajpendo.1996.271.5.e889. [PMID: 8944677]
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  • A K Ohlin, G Landes, P Bourdon, C Oppenheimer, R Wydro, J Stenflo. Beta-hydroxyaspartic acid in the first epidermal growth factor-like domain of protein C. Its role in Ca2+ binding and biological activity. The Journal of biological chemistry. 1988 Dec; 263(35):19240-8. doi: . [PMID: 2461936]
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