lychnopholide (BioDeep_00000316523)

   

natural product


代谢物信息卡片


lychnopholide

化学式: C20H22O6 (358.1416)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(natural_products) 100%

分子结构信息

SMILES: C/C(C(O1)=C2)=C/[C@@H](OC(C3=C)=O)[C@H]3[C@@H](OC(/C(C)=C\C)=O)C[C@]1(C)C2=O
InChI: InChI=1S/C20H22O6/c1-6-10(2)18(22)25-15-9-20(5)16(21)8-13(26-20)11(3)7-14-17(15)12(4)19(23)24-14/h6-8,14-15,17H,4,9H2,1-3,5H3/b10-6-,11-7-/t14-,15+,17+,20-/m1/s1

描述信息

同义名列表

1 个代谢物同义名

lychnopholide



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Ana Catharina Fernandes Pereira Ferreira Bernardes, Rafaela Cunha Matosinhos, Marcela Carolina de Paula Michel Araújo, Camila Helena Barros, Rodrigo Dian de Oliveira Aguiar Soares, Daniela Caldeira Costa, Daniela Sachs, Dênia Antunes Saúde-Guimarães. Sesquiterpene lactones from Lychnophora species: Antinociceptive, anti-inflammatory, and antioxidant pathways to treat acute gout. Journal of ethnopharmacology. 2021 Apr; 269(?):113738. doi: 10.1016/j.jep.2020.113738. [PMID: 33359866]
  • Clarice Izumi, Helen Julie Laure, Nayara Gonçalves Barbosa, Carolina Hassibe Thomé, Germano Aguiar Ferreira, João Paulo Barreto Sousa, Norberto Peporine Lopes, José César Rosa. Sequesterpene Lactones Isolated from a Brazilian Cerrado Plant (Eremanthus spp.) as Anti-Proliferative Compounds, Characterized by Functional and Proteomic Analysis, are Candidates for New Therapeutics in Glioblastoma. International journal of molecular sciences. 2020 07; 21(13):. doi: 10.3390/ijms21134713. [PMID: 32630308]
  • Yulin Ren, Esperanza J Carcache de Blanco, James R Fuchs, Djaja D Soejarto, Joanna E Burdette, Steven M Swanson, A Douglas Kinghorn. Potential Anticancer Agents Characterized from Selected Tropical Plants. Journal of natural products. 2019 03; 82(3):657-679. doi: 10.1021/acs.jnatprod.9b00018. [PMID: 30830783]
  • Renata Tupinambá Branquinho, Gwenaelle Pound-Lana, Matheus Marques Milagre, Dênia Antunes Saúde-Guimarães, José Mário Carneiro Vilela, Margareth Spangler Andrade, Marta de Lana, Vanessa Carla Furtado Mosqueira. Increased Body Exposure to New Anti-Trypanosomal Through Nanoencapsulation. Scientific reports. 2017 08; 7(1):8429. doi: 10.1038/s41598-017-08469-x. [PMID: 28814794]
  • Larissa Lachi-Silva, João Paulo Barreto Sousa, Maiara Camotti Montanha, Sherwin K B Sy, João Luis Callegari Lopes, Denise Brentan Silva, Norberto Peporine Lopes, Andréa Diniz, Elza Kimura. Rapid and efficient method for the quantification of lychnopholide in rat plasma by liquid chromatography-tandem mass spectrometry for pharmacokinetic application. Biomedical chromatography : BMC. 2016 Jul; 30(7):1092-1096. doi: 10.1002/bmc.3654. [PMID: 26577838]
  • Larissa Lachi-Silva, Sherwin K B Sy, Alexander Voelkner, João Paulo Barreto de Sousa, João Luis C Lopes, Denise B Silva, Norberto P Lopes, Elza Kimura, Hartmut Derendorf, Andrea Diniz. Simultaneous Characterization of Intravenous and Oral Pharmacokinetics of Lychnopholide in Rats by Transit Compartment Model. Planta medica. 2015 Aug; 81(12-13):1121-7. doi: 10.1055/s-0035-1546214. [PMID: 26218336]
  • Fernanda C Ferrari, Leidiane C Ferreira, Maíra R Souza, Andrea Grabe-Guimarães, Carmen A Paula, Simone A Rezende, Dênia A Saúde-Guimarães. Anti-inflammatory sesquiterpene lactones from Lychnophora trichocarpha Spreng. (Brazilian Arnica). Phytotherapy research : PTR. 2013 Mar; 27(3):384-9. doi: 10.1002/ptr.4736. [PMID: 22619042]