tert-Butyl ethyl ether (BioDeep_00000312590)

   

Volatile Flavor Compounds


代谢物信息卡片


tert-Butyl ethyl ether

化学式: C6H14O (102.10445940000001)
中文名称: 乙基叔丁基醚, 叔丁基乙醚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCOC(C)(C)C
InChI: InChI=1S/C6H14O/c1-5-7-6(2,3)4/h5H2,1-4H3

描述信息

同义名列表

3 个代谢物同义名

tert-Butyl ethyl ether; etbe; tert-Butyl ethyl ether



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Henry C G Nicholls, Stephen A Rolfe, Helen E H Mallinson, Markus Hjort, Michael J Spence, Matthijs Bonte, Steven F Thornton. Distribution of ETBE-degrading microorganisms and functional capability in groundwater, and implications for characterising aquifer ETBE biodegradation potential. Environmental science and pollution research international. 2022 Jan; 29(1):1223-1238. doi: 10.1007/s11356-021-15606-7. [PMID: 34350568]
  • S F Thornton, H C G Nicholls, S A Rolfe, H E H Mallinson, M J Spence. Biodegradation and fate of ethyl tert-butyl ether (ETBE) in soil and groundwater: A review. Journal of hazardous materials. 2020 06; 391(?):122046. doi: 10.1016/j.jhazmat.2020.122046. [PMID: 32145642]
  • H C G Nicholls, H E H Mallinson, S A Rolfe, M Hjort, M J Spence, S F Thornton. Influence of contaminant exposure on the development of aerobic ETBE biodegradation potential in microbial communities from a gasoline-impacted aquifer. Journal of hazardous materials. 2020 04; 388(?):122022. doi: 10.1016/j.jhazmat.2020.122022. [PMID: 31962211]
  • Zuquan Weng, Yuhong Shi, Megumi Suda, Yukie Yanagiba, Toshihiro Kawamoto, Tamie Nakajima, Rui-Sheng Wang. Inhalation exposure to low levels of ethyl tertiary butyl ether: Its genetic effects were significantly modified by ALDH2 activity. Environmental and molecular mutagenesis. 2019 03; 60(2):145-153. doi: 10.1002/em.22256. [PMID: 30474146]
  • Susan J Borghoff, Caroline Ring, Marcy I Banton, Teresa L Leavens. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to α2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes. Journal of applied toxicology : JAT. 2017 05; 37(5):621-640. doi: 10.1002/jat.3412. [PMID: 27885692]
  • Laura Campo, Federica Rossella, Rosa Mercadante, Silvia Fustinoni. Exposure to BTEX and Ethers in Petrol Station Attendants and Proposal of Biological Exposure Equivalents for Urinary Benzene and MTBE. The Annals of occupational hygiene. 2016 Apr; 60(3):318-33. doi: 10.1093/annhyg/mev083. [PMID: 26667482]
  • María Balseiro-Romero, Petra S Kidd, Carmen Monterroso. Leachability of volatile fuel compounds from contaminated soils and the effect of plant exudates: A comparison of column and batch leaching tests. Journal of hazardous materials. 2016 Mar; 304(?):481-9. doi: 10.1016/j.jhazmat.2015.11.017. [PMID: 26619047]
  • Keith D Salazar, Christopher J Brinkerhoff, Janice S Lee, Weihsueh A Chiu. Development and application of a rat PBPK model to elucidate kidney and liver effects induced by ETBE and tert-butanol. Toxicology and applied pharmacology. 2015 Nov; 288(3):439-52. doi: 10.1016/j.taap.2015.08.015. [PMID: 26341290]
  • Petra Bombach, Norbert Nägele, Mònica Rosell, Hans H Richnow, Anko Fischer. Evaluation of ethyl tert-butyl ether biodegradation in a contaminated aquifer by compound-specific isotope analysis and in situ microcosms. Journal of hazardous materials. 2015 Apr; 286(?):100-6. doi: 10.1016/j.jhazmat.2014.12.028. [PMID: 25559863]
  • Arata Saito, Toshiaki Sasaki, Tatuya Kasai, Taku Katagiri, Tomoshi Nishizawa, Tadashi Noguchi, Shigetoshi Aiso, Kasuke Nagano, Shoji Fukushima. Hepatotumorigenicity of ethyl tertiary-butyl ether with 2-year inhalation exposure in F344 rats. Archives of toxicology. 2013 May; 87(5):905-14. doi: 10.1007/s00204-012-0997-x. [PMID: 23389738]
  • Tadashi Noguchi, Tomoyuki Kamigaito, Taku Katagiri, Hitomi Kondou, Kazunori Yamazaki, Shigetoshi Aiso, Tomoshi Nishizawa, Kasuke Nagano, Shoji Fukushima. Lack of micronucleus induction activity of ethyl tertiary-butyl ether in the bone marrow of F344 rats by sub-chronic drinking-water treatment, inhalation exposure, or acute intraperitoneal injection. The Journal of toxicological sciences. 2013; 38(6):913-24. doi: 10.2131/jts.38.913. [PMID: 24213011]
  • Françoise Fayolle-Guichard, Jonathan Durand, Mathilde Cheucle, Mònica Rosell, Rory Julien Michelland, Jean-Philippe Tracol, Françoise Le Roux, Geneviève Grundman, Olivier Atteia, Hans H Richnow, Alain Dumestre, Yves Benoit. Study of an aquifer contaminated by ethyl tert-butyl ether (ETBE): site characterization and on-site bioremediation. Journal of hazardous materials. 2012 Jan; 201-202(?):236-43. doi: 10.1016/j.jhazmat.2011.11.074. [PMID: 22177017]
  • Masaaki Suzuki, Kazunori Yamazaki, Hirokazu Kano, Shigetoshi Aiso, Kasuke Nagano, Shoji Fukushima. No carcinogenicity of ethyl tertiary-butyl ether by 2-year oral administration in rats. The Journal of toxicological sciences. 2012; 37(6):1239-46. doi: 10.2131/jts.37.1239. [PMID: 23208438]
  • Akihiro Hagiwara, Yuko Doi, Norio Imai, Hironao Nakashima, Takahiro Ono, Mayumi Kawabe, Fumio Furukawa, Seiko Tamano, Kasuke Nagano, Shoji Fukushima. Medium-term multi-organ carcinogenesis bioassay of ethyl tertiary-butyl ether in rats. Toxicology. 2011 Nov; 289(2-3):160-6. doi: 10.1016/j.tox.2011.08.007. [PMID: 21864636]
  • Ingrid Elisia, David D Kitts. Quantification of hexanal as an index of lipid oxidation in human milk and association with antioxidant components. Journal of clinical biochemistry and nutrition. 2011 Nov; 49(3):147-52. doi: 10.3164/jcbn.10-142. [PMID: 22128211]
  • Silvia Fustinoni, Federica Rossella, Laura Campo, Rosa Mercadante, Pier Alberto Bertazzi. Urinary BTEX, MTBE and naphthalene as biomarkers to gain environmental exposure profiles of the general population. The Science of the total environment. 2010 Jun; 408(14):2840-9. doi: 10.1016/j.scitotenv.2010.03.017. [PMID: 20417546]
  • Ann de Peyster, Bradley Stanard, Christian Westover. Effect of ETBE on reproductive steroids in male rats and rat Leydig cell cultures. Toxicology letters. 2009 Oct; 190(1):74-80. doi: 10.1016/j.toxlet.2009.06.879. [PMID: 19595749]
  • Noushin Rastkari, Reza Ahmadkhaniha, Masud Yunesian. Single-walled carbon nanotubes as an effective adsorbent in solid-phase microextraction of low level methyl tert-butyl ether, ethyl tert-butyl ether and methyl tert-amyl ether from human urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2009 May; 877(14-15):1568-74. doi: 10.1016/j.jchromb.2009.04.002. [PMID: 19395320]
  • Darren M Soanes, Intikhab Alam, Mike Cornell, Han Min Wong, Cornelia Hedeler, Norman W Paton, Magnus Rattray, Simon J Hubbard, Stephen G Oliver, Nicholas J Talbot. Comparative genome analysis of filamentous fungi reveals gene family expansions associated with fungal pathogenesis. PloS one. 2008 Jun; 3(6):e2300. doi: 10.1371/journal.pone.0002300. [PMID: 18523684]
  • Douglas McGregor. Ethyl tertiary-butyl ether: a toxicological review. Critical reviews in toxicology. 2007 May; 37(4):287-312. doi: 10.1080/10408440601177723. [PMID: 17453936]
  • Licia Scibetta, Laura Campo, Rosa Mercadante, Vito Foà, Silvia Fustinoni. Determination of low level methyl tert-butyl ether, ethyl tert-butyl ether and methyl tert-amyl ether in human urine by HS-SPME gas chromatography/mass spectrometry. Analytica chimica acta. 2007 Jan; 581(1):53-62. doi: 10.1016/j.aca.2006.07.083. [PMID: 17386425]
  • W Dekant, U Bernauer, E Rosner, A Amberg. Biotransformation of MTBE, ETBE, and TAME after inhalation or ingestion in rats and humans. Research report (Health Effects Institute). 2001 May; ?(102):29-71; discussion 95. doi: NULL. [PMID: 11504147]
  • A Amberg, E Rosner, W Dekant. Biotransformation and kinetics of excretion of ethyl tert-butyl ether in rats and humans. Toxicological sciences : an official journal of the Society of Toxicology. 2000 Feb; 53(2):194-201. doi: 10.1093/toxsci/53.2.194. [PMID: 10696767]
  • A Nihlén, G Johanson. Physiologically based toxicokinetic modeling of inhaled ethyl tertiary-butyl ether in humans. Toxicological sciences : an official journal of the Society of Toxicology. 1999 Oct; 51(2):184-94. doi: 10.1093/toxsci/51.2.184. [PMID: 10543020]
  • M A Medinsky, D C Wolf, R C Cattley, B Wong, D B Janszen, G M Farris, G A Wright, J A Bond. Effects of a thirteen-week inhalation exposure to ethyl tertiary butyl ether on fischer-344 rats and CD-1 mice. Toxicological sciences : an official journal of the Society of Toxicology. 1999 Sep; 51(1):108-18. doi: 10.1093/toxsci/51.1.108. [PMID: 10496682]
  • A Nihlén, A Löf, G Johanson. Controlled ethyl tert-butyl ether (ETBE) exposure of male volunteers. I. Toxicokinetics. Toxicological sciences : an official journal of the Society of Toxicology. 1998 Nov; 46(1):1-10. doi: 10.1006/toxs.1998.2516. [PMID: 9928663]
  • U Bernauer, A Amberg, D Scheutzow, W Dekant. Biotransformation of 12C- and 2-13C-labeled methyl tert-butyl ether, ethyl tert-butyl ether, and tert-butyl alcohol in rats: identification of metabolites in urine by 13C nuclear magnetic resonance and gas chromatography/mass spectrometry. Chemical research in toxicology. 1998 Jun; 11(6):651-8. doi: 10.1021/tx970215v. [PMID: 9625733]
  • G Johanson, A Nihlén, A Löf. Toxicokinetics and acute effects of MTBE and ETBE in male volunteers. Toxicology letters. 1995 Dec; 82-83(?):713-8. doi: 10.1016/0378-4274(95)03589-3. [PMID: 8597131]
  • A Nihlen, A Lof, G Johanson. Liquid/air partition coefficients of methyl and ethyl T-butyl ethers, T-amyl methyl ether, and T-butyl alcohol. Journal of exposure analysis and environmental epidemiology. 1995 Oct; 5(4):573-82. doi: ". [PMID: 8938250]