PIP2(18:0/16:2(9Z,12Z)) (BioDeep_00000031242)
human metabolite Endogenous
代谢物信息卡片
化学式: C43H81O19P3 (994.4584666)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OC1C(C(C(C(C1O)OP(=O)(O)O)OP(=O)(O)O)O)O)OC(=O)CCCCCCCC=CCC=CCCC
InChI: InChI=1S/C43H81O19P3/c1-3-5-7-9-11-13-15-17-18-20-21-23-25-27-29-31-36(44)57-33-35(59-37(45)32-30-28-26-24-22-19-16-14-12-10-8-6-4-2)34-58-65(55,56)62-41-38(46)39(47)42(60-63(49,50)51)43(40(41)48)61-64(52,53)54/h8,10,14,16,35,38-43,46-48H,3-7,9,11-13,15,17-34H2,1-2H3,(H,55,56)(H2,49,50,51)(H2,52,53,54)/t35-,38?,39?,40?,41+,42?,43+/m1/s1
描述信息
PIP2(18:0/16:2(9Z,12Z)) is a phosphatidylinositol bisphosphate. Phosphatidylinositol bisphosphates are acidic (anionic) phospholipids that consist of a phosphatidic acid backbone, linked via the phosphate group to a bisphosphorylated inositol (hexahydroxycyclohexane). Phosphatidylinositol bisphosphates are generated from phosphatidylinositols which are phosphorylated by a number of different kinases that place the phosphate moiety on positions 4 and 5 of the inositol ring, although position 3 can also be phosphorylated. Phosphatidylinositols bisphosphates can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. Fatty acids containing 18 and 20 carbons are the most common. PIP2(18:0/16:2(9Z,12Z)), in particular, consists of one chain of stearic acid at the C-1 position and one chain of (9Z,12Z-hexadecadienoate) at the C-2 position. The stearic acid moiety is derived from animal fats, coco butter and sesame oil, while the (9Z,12Z-hexadecadienoate) moiety is derived from fish oils. The most important phosphatidylinositol bisphosphate in both quantitative and biological terms is phosphatidylinositol 4,5-bisphosphate. Phosphatidylinositol and the phosphatidylinositol phosphates are the main source of diacylglycerols that serve as signaling molecules, via the action of phospholipase C enzymes. Phosphatidylinositols phosphates are usually present at low levels only in tissues, typically at about 1 to 3\\% of the concentration of phosphatidylinositol. [HMDB]
PIP2(18:0/16:2(9Z,12Z)) is a phosphatidylinositol bisphosphate. Phosphatidylinositol bisphosphates are acidic (anionic) phospholipids that consist of a phosphatidic acid backbone, linked via the phosphate group to a bisphosphorylated inositol (hexahydroxycyclohexane). Phosphatidylinositol bisphosphates are generated from phosphatidylinositols which are phosphorylated by a number of different kinases that place the phosphate moiety on positions 4 and 5 of the inositol ring, although position 3 can also be phosphorylated. Phosphatidylinositols bisphosphates can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. Fatty acids containing 18 and 20 carbons are the most common. PIP2(18:0/16:2(9Z,12Z)), in particular, consists of one chain of stearic acid at the C-1 position and one chain of (9Z,12Z-hexadecadienoate) at the C-2 position. The stearic acid moiety is derived from animal fats, coco butter and sesame oil, while the (9Z,12Z-hexadecadienoate) moiety is derived from fish oils. The most important phosphatidylinositol bisphosphate in both quantitative and biological terms is phosphatidylinositol 4,5-bisphosphate. Phosphatidylinositol and the phosphatidylinositol phosphates are the main source of diacylglycerols that serve as signaling molecules, via the action of phospholipase C enzymes. Phosphatidylinositols phosphates are usually present at low levels only in tissues, typically at about 1 to 3\\% of the concentration of phosphatidylinositol.
同义名列表
20 个代谢物同义名
{[(4S,6S)-4-({[(2R)-2-[(9Z,12Z)-hexadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)-2,3,5-trihydroxy-6-(phosphonooxy)cyclohexyl]oxy}phosphonic acid; [(4S,6S)-4-{[(2R)-2-[(9Z,12Z)-hexadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propoxy(hydroxy)phosphoryl]oxy}-2,3,5-trihydroxy-6-(phosphonooxy)cyclohexyl]oxyphosphonic acid; {[(1S,3S)-3-({[(2R)-2-[(9Z,12Z)-hexadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)-2,4,5-trihydroxy-6-(phosphonooxy)cyclohexyl]oxy}phosphonate; 1-Octadecanoyl-2-(9Z,12Z-hexadecadienoate)-sn-glycero-3-phospho-(1-myo-inositol-3,4-bisphosphate); 1-Stearoyl-2-(9Z,12Z-hexadecadienoate)-sn-glycero-3-phosphoinositol-bisphosphate; 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate; Phosphatidylinositol diphosphate(18:0/16:2W4); Phosphatidylinositol diphosphate(18:0/16:2n4); 1-Octadecanoyl-2-(9Z,12Z-hexadecadienoic acid; Phosphatidylinositol diphosphate(18:0/16:2); 1-Stearoyl-2-(9Z,12Z-hexadecadienoic acid; 1-Octadecanoyl-2-(9Z,12Z-hexadecadienoate; Phosphatidylinositol diphosphate(34:2); 1-Stearoyl-2-(9Z,12Z-hexadecadienoate; PIP2[3,4](18:0/16:2(9Z,12Z)); PIP2(18:0/16:2(9Z,12Z)); PIP2(18:0/16:2W4); PIP2(18:0/16:2n4); PIP2(18:0/16:2); PIP2(34:2)
数据库引用编号
6 个数据库交叉引用编号
- KEGG: C00626
- PubChem: 53480252
- HMDB: HMDB0010061
- MetaCyc: Phosphatidylinositols
- foodb: FDB027244
- chemspider: 24767938
分类词条
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1 个相关的物种来源信息
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