Dimethyl sulfoxide (BioDeep_00000003117)

 

Secondary id: BioDeep_00000405805

human metabolite Volatile Flavor Compounds


代谢物信息卡片


Research ind. corp. brand 1 OF dimethyl sulfoxide

化学式: C2H6OS (78.0139346)
中文名称: 二甲基亚砜
谱图信息: 最多检出来源 Homo sapiens(feces) 0.6%

分子结构信息

SMILES: CS(=O)C
InChI: InChI=1S/C2H6OS/c1-4(2)3/h1-2H3

描述信息

Dimethyl sulfoxide (DMSO) is a key dipolar aprotic solvent. It is less toxic than other members of this class: dimethylformamide, dimethylacetamide, N-methyl-2-pyrrolidone, HMPA. Dimethyl sulfoxide is the chemical compound (CH3)2SO. This colorless liquid is an important "dipolar aprotic solvent." It is readily miscible in a wide range of organic solvents as well as water. It has a distinctive property of penetrating the skin very readily, allowing the handler to taste it. Some describe it as an "oyster-like" taste, others claim it tastes like garlic. DMSO is also employed as a rinsing agent in the electronics industry and, in its deuterated form (DMSO-d6), is a useful solvent in NMR due to its ability to dissolve a wide range of chemical compounds and its minimal interference with the sample signals. In cryobiology DMSO has been used as a cryoprotectant and is still an important constituent of cryoprotectant vitrification mixtures used to preserve organs, tissues, and cell suspensions. It is particularly important in the freezing and long-term storage of embryonic stem cells and hematopoietic stem cell, which are often frozen in a mixture of 10\\% DMSO and 90\\% fetal calf serum. As part of an autologous bone marrow transplant the DMSO is re-infused along with the patients own hematopoietic stem cell. Dimethyl sulfoxide is a by-product of wood pulping. One of the leading suppliers of DMSO is the Gaylord company in the USA. DMSO is frequently used as solvent in a number of chemical reactions. In particular it is an excellent reaction solvent for SN2 alkylations: it is possible to alkylate indoles with very high yields using potassium hydroxide as the base and a similar reaction also occurs with phenols. DMSO can be reacted with methyl iodide to form a sulfoxonium ion which can be reacted with sodium hydride to form a sulfur ylide. The methyl groups of DMSO are somewhat acidic in character (pKa=35) due to the stabilization of the resultant anions by the sulfoxide group.
M - Musculo-skeletal system > M02 - Topical products for joint and muscular pain > M02A - Topical products for joint and muscular pain
Found in broad bean Phaseolus vulgaris, alfalfa Medicago sativa and many other plants. Flavouring agent
G - Genito urinary system and sex hormones > G04 - Urologicals > G04B - Urologicals
D020011 - Protective Agents > D003451 - Cryoprotective Agents
D000975 - Antioxidants > D016166 - Free Radical Scavengers
D020011 - Protective Agents > D000975 - Antioxidants
D012997 - Solvents
Same as: D01043

同义名列表

44 个代谢物同义名

Research ind. corp. brand 1 OF dimethyl sulfoxide; Research ind. corp. brand 2 OF dimethyl sulfoxide; Merckle brand OF dimethyl sulfoxide; Shire brand OF dimethyl sulfoxide; (Methylsulfinyl)methane; Methylsulphinylmethane; Dimethyl sulphur oxide; methanesulfinylmethane; Sulphinylbis(methane); Dimethyl sulfur oxide; Dimethyli sulphoxidum; methylsulfinylmethane; Dimethyli sulfoxidum; Sulphoxide, dimethyl; Sulfinylbis(methane); Dimethyl sulphoxide; Dimethyl sulfoxixde; Sulfoxide, dimethyl; Dimetil sulphoxido; Dimethylsulphoxide; Dimethyl sulpoxide; dimethyl sulfoxide; Dimethylsulphoxyde; Dimethylsulfoxyde; Dimetil sulfoxido; Dimethylsulfoxide; Dimethylsulphoxid; Dimethylsulphinyl; Dimethylsulfoxid; Rheumabene; Sclerosol; rimso 100; Rimso-50; (CH3)2SO; Rimso 50; Dimexide; Dermavet; S(O)Me2; Rimso50; Rimso; Zymso; DMSO; Dimethyl sulfoxide; Dimethyl sulfoxide



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(9)

PlantCyc(0)

代谢反应

25 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(23)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(2)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Aline de Souza, Cauê Benito Scarim, Paulo Cesar Cotrim, Fernando Barbosa Junior, Bruno Alves Rocha, Leandro Augusto Calixto, Cristiano Jesus Correia, Gabriel Lima de Barros Araújo, Raimar Löbenberg, Nádia Araci Bou-Chacra, Ana Cristina Breithaupt-Faloppa. Hydroxymethylnitrofurazone lymphatic uptake with nanostructured lipid carrier after oral administration in rats. Nanomedicine (London, England). 2024 02; 19(4):293-301. doi: 10.2217/nnm-2023-0263. [PMID: 38270378]
  • Özlem Sultan Aslantürk. Cytotoxic and genotoxic effects of triphenyl phosphate on root tip cells of Allium cepa L. Toxicology in vitro : an international journal published in association with BIBRA. 2024 Feb; 94(?):105734. doi: 10.1016/j.tiv.2023.105734. [PMID: 37981031]
  • Dan-Yang Shi, Yu Zheng, Qiang-Sheng Guo, Can Gong, Xu Xu, Jian-Ping Gao. Determination of total phenol and six polyphenolic components in the polyphenol extract of Cinnamomi cortex by quantitative nuclear magnetic resonance spectroscopy. Analytical methods : advancing methods and applications. 2023 12; 15(47):6561-6570. doi: 10.1039/d3ay01501g. [PMID: 38009205]
  • Agata Wilczańska, Barbara Sparzak-Stefanowska, Adam Kokotkiewicz, Anna Jesionek, Aleksandra Królicka, Maria Łuczkiewicz, Mirosława Krauze-Baranowska. Biotechnological strategies for controlled accumulation of flavones in hairy root culture of Scutellaria lateriflora L. Scientific reports. 2023 11; 13(1):20422. doi: 10.1038/s41598-023-47757-7. [PMID: 37990031]
  • Javier Stelling-Férez, Santiago López-Miranda, José Antonio Gabaldón, Francisco José Nicolás. Oleanolic Acid Complexation with Cyclodextrins Improves Its Cell Bio-Availability and Biological Activities for Cell Migration. International journal of molecular sciences. 2023 Oct; 24(19):. doi: 10.3390/ijms241914860. [PMID: 37834307]
  • Kaiwen Zhao, Hongqiao Zhu, Xiaomin He, Pengcheng Du, Taiping Liang, Yudong Sun, Zaiping Jing, Jian Zhou. Senkyunolide I ameliorates thoracic aortic aneurysm and dissection in mice via inhibiting the oxidative stress and apoptosis of endothelial cells. Biochimica et biophysica acta. Molecular basis of disease. 2023 10; 1869(7):166819. doi: 10.1016/j.bbadis.2023.166819. [PMID: 37499930]
  • Taehyung Lee, Woorim Yeom, Hoikyung Kim, Larry R Beuchat, Jee-Hoon Ryu. Influence of diluent on antimicrobial activity of cinnamon bark essential oil vapor against Staphylococcus aureus and Salmonella enterica on a laboratory medium and beef jerky. Food microbiology. 2023 Oct; 115(?):104335. doi: 10.1016/j.fm.2023.104335. [PMID: 37567638]
  • Antigoni Margariti, Vasiliki D Papakonstantinou, George M Stamatakis, Constantinos A Demopoulos, Christina Machalia, Evangelia Emmanouilidou, Gregor Schnakenburg, Maria-Christina Nika, Nikolaos S Thomaidis, Athanassios I Philippopoulos. First-Row Transition Metal Complexes Incorporating the 2-(2'-pyridyl)quinoxaline Ligand (pqx), as Potent Inflammatory Mediators: Cytotoxic Properties and Biological Activities against the Platelet-Activating Factor (PAF) and Thrombin. Molecules (Basel, Switzerland). 2023 Oct; 28(19):. doi: 10.3390/molecules28196899. [PMID: 37836742]
  • Bee Chin Tan, Alida Mahyuddin, S Nagarajan M P Sockalingam, Ahmad Shuhud Irfani Zakaria. Preliminary in vitro cytotoxic evaluation of Uncaria gambier (Hunt) Roxb extract as a potential herbal-based pulpotomy medicament. BMC complementary medicine and therapies. 2023 Sep; 23(1):331. doi: 10.1186/s12906-023-04163-w. [PMID: 37730579]
  • Miaomiao Wang, Mingxu Wang, Wei Li, Yameng Liu, Feng Qiu. Single-cell detection of DMSO promoted HL-60 differentiation towards granulocyte based on DC-iDEP for medicine screening. Biotechnology journal. 2023 Aug; ?(?):e2300073. doi: 10.1002/biot.202300073. [PMID: 37640006]
  • H Li, Y Deng, T Wang, K Huang, C Yu, C Chen. [Danshenxinkun B protects human umbilical vein endothelial cells against ox-LDL-induced injury by inhibiting pyroptosis and the NF-κB/NLRP3 pathway]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 2023 Aug; 43(8):1425-1431. doi: 10.12122/j.issn.1673-4254.2023.08.21. [PMID: 37712281]
  • ShengHao Chen, YanLan Liang, YuanYuan Li, Yue Sun, Yang He. Determination of rhein and physcion in rhubarb by microchip capillary electrophoresis in mixed hydro-organic solvent combined with laser-induced fluorescence detection. Journal of separation science. 2023 Jul; ?(?):e2300192. doi: 10.1002/jssc.202300192. [PMID: 37507831]
  • Carolina Victal Garbelotti, Adriana Grandis, Eduardo Crevelin, Marcos Silveira Buckeridge, Luiz Alberto Beraldo de Moraes, Richard John Ward. Glycomic profiling identifies key-structural differences in three arabinoxylan fractions from sugarcane culms. Carbohydrate polymers. 2023 Jun; 310(?):120694. doi: 10.1016/j.carbpol.2023.120694. [PMID: 36925235]
  • Ioanna Poulopoulou, Mark James Horgan, Bianka Siewert, Michaela Siller, Luisa Palmieri, Eftychia Martinidou, Stefan Martens, Pietro Fusani, Veronika Temml, Hermann Stuppner, Matthias Gauly. In vitro evaluation of the effects of methanolic plant extracts on the embryonation rate of Ascaridia galli eggs. Veterinary research communications. 2023 Jun; 47(2):409-419. doi: 10.1007/s11259-022-09958-9. [PMID: 35727416]
  • Lenka Burdejova, Blanka Tobolkova, Martin Polovka, Jarmila Neugebauerova. Differentiation of Medicinal Plants According to Solvents, Processing, Origin, and Season by Means of Multivariate Analysis of Spectroscopic and Liquid Chromatography Data. Molecules (Basel, Switzerland). 2023 May; 28(10):. doi: 10.3390/molecules28104075. [PMID: 37241816]
  • Segun A Aderibigbe, Sunday O Idowu, Ajibola A Olaniyi. Isotonic, aqueous-based media as simple and suitable test media for short-term Haemonchus placei adult worm motility assay. Experimental parasitology. 2023 Mar; 249(?):108516. doi: 10.1016/j.exppara.2023.108516. [PMID: 36967034]
  • B J Sampson, N Tabanca, C T Werle, S J Stringer, D E Wedge, R Moraes. Insecticidal Activity of Jatropha Extracts Against the Azalea Lace Bug, Stephanitis pyrioides (Hemiptera: Tingidae). Journal of economic entomology. 2023 02; 116(1):192-201. doi: 10.1093/jee/toac187. [PMID: 36534944]
  • Wei Huang, Guodong Cao, Chengliang Deng, Yanyan Chen, Tao Wang, Da Chen, Zongwei Cai. Adverse effects of triclosan on kidney in mice: Implication of lipid metabolism disorders. Journal of environmental sciences (China). 2023 Feb; 124(?):481-490. doi: 10.1016/j.jes.2021.11.032. [PMID: 36182156]
  • Chang Yu Kan, Jing Xuan H'ng, Andy Goh, Frederick Smales, Eng Lai Tan, Shiming Zhang, Mallikarjuna Rao Pichika, Abhishek Parolia. Effect of Sustained Systemic Administration of Ginger (Z officinale) Rhizome Extracts on Salivary Flow in Mice. International dental journal. 2023 Feb; 73(1):63-70. doi: 10.1016/j.identj.2022.04.011. [PMID: 35725589]
  • Bruna B Segat, Lucas B Menezes, Rodrigo Cervo, Roberta Cargnelutti, Hugo Tolentino, Alexandra Latini, Adolfo Horn, Christiane Fernandes. Scavenging of reactive species probed by EPR and ex-vivo nanomolar reduction of lipid peroxidation of manganese complexes. Journal of inorganic biochemistry. 2023 02; 239(?):112060. doi: 10.1016/j.jinorgbio.2022.112060. [PMID: 36402588]
  • Yang Yang, Dongjuan Zhang, Minghui Song, Chao Wang, Jiayi Lv, Jie Zhou, Meihan Chen, Lu Ma, Changlin Mei. Macrophages promote heat stress nephropathy in mice via the C3a-C3aR-TNF pathway. Immunobiology. 2023 Jan; 228(2):152337. doi: 10.1016/j.imbio.2023.152337. [PMID: 36689826]
  • Chunsheng Bao, Guge Wuyun Sure, Yufeng Gao. [Mongolian medicine Zhenbao Pill (Eridon Uril) inhibits inflammation and apoptosis in hippocampal neuronal cells of oxyglucose deprived/reoxygenated mice through activation of SIRT1/NF-κB pathway]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 2023 Num; 39(11):1003-1009. doi: . [PMID: 37980552]
  • Muddukrishnaiah Kotakonda, Makesh Marappan, Prabaharan Dharmar, Balasubramaniyan Sakthivel, Prasad Sunnapu. Isolation and Identification of Bioactive Compounds with Antimicrobial Activity from Marine Facultative Anaerobe, Bacillus subtilis. Current pharmaceutical biotechnology. 2023; 24(5):698-707. doi: 10.2174/1389201023666220801090810. [PMID: 35927910]
  • Maham Khan, Tariq Khan, Shahid Wahab, Muhammad Aasim, Tauqir A Sherazi, Muhammad Zahoor, Soon-Il Yun. Solvent based fractional biosynthesis, phytochemical analysis, and biological activity of silver nanoparticles obtained from the extract of Salvia moorcroftiana. PloS one. 2023; 18(10):e0287080. doi: 10.1371/journal.pone.0287080. [PMID: 37883497]
  • Masato Kondoh, Arisa Sano, Izuru Kawamura, Taka-Aki Ishibashi. Total Internal Reflection Raman Spectra of Alamethicin Interacting with Supported Lipid Bilayers at a Silica/Water Interface. The journal of physical chemistry. B. 2022 12; 126(50):10712-10720. doi: 10.1021/acs.jpcb.2c06371. [PMID: 36440848]
  • Iwona Budziak-Wieczorek, Lidia Ślusarczyk, Beata Myśliwa-Kurdziel, Martyna Kurdziel, Monika Srebro-Hooper, Izabela Korona-Glowniak, Mariusz Gagoś, Grzegorz Gładyszewski, Andrzej Stepulak, Dariusz Kluczyk, Arkadiusz Matwijczuk. Spectroscopic characterization and assessment of microbiological potential of 1,3,4-thiadiazole derivative showing ESIPT dual fluorescence enhanced by aggregation effects. Scientific reports. 2022 12; 12(1):22140. doi: 10.1038/s41598-022-26690-1. [PMID: 36550169]
  • Yihui Dong, Nir Kampf, Yaelle Schilt, Wei Cao, Uri Raviv, Jacob Klein. Dehydration does not affect lipid-based hydration lubrication. Nanoscale. 2022 Dec; 14(48):18241-18252. doi: 10.1039/d2nr04799c. [PMID: 36468753]
  • Sadettin Demirel. Rosa damascena Miller essential oil relaxes rat trachea via KV channels, KATP channels, and BKCa channels. Prostaglandins & other lipid mediators. 2022 12; 163(?):106673. doi: 10.1016/j.prostaglandins.2022.106673. [PMID: 36115499]
  • Mika Ishigaki, Hirofumi Hitomi, Yukihiro Ozaki, Akira Nishiyama. Exposing intracellular molecular changes during the differentiation of human-induced pluripotent stem cells into erythropoietin-producing cells using Raman spectroscopy and imaging. Scientific reports. 2022 11; 12(1):20454. doi: 10.1038/s41598-022-24725-1. [PMID: 36443362]
  • Mina Sadat Izadi, Farzaneh Eskandari, Fatemeh Binayi, Mina Salimi, Fatemeh Sadat Rashidi, Mehdi Hedayati, Leila Dargahi, Hossein Ghanbarian, Homeira Zardooz. Oxidative and endoplasmic reticulum stress develop adverse metabolic effects due to the high-fat high-fructose diet consumption from birth to young adulthood. Life sciences. 2022 Nov; 309(?):120924. doi: 10.1016/j.lfs.2022.120924. [PMID: 36063978]
  • Yuanyuan Ma, Yelong Ji, Li Xu, Zheng Li, Shengjin Ge. Obesity aggravated hippocampal-dependent cognitive impairment after sleeve gastrectomy in C57/BL6J mice via SIRT1/CREB/BDNF pathway. Experimental brain research. 2022 Nov; 240(11):2897-2906. doi: 10.1007/s00221-022-06465-w. [PMID: 36114835]
  • Nilson Ferreira de Oliveira Neto, Jéssica Fernanda Sena Bonvicini, Gabriela Leite de Souza, Mariana Brentini Santiago, Rodrigo Cássio Sola Veneziani, Sérgio Ricardo Ambrósio, Jairo Kenupp Bastos, Marcelo José Barbosa Silva, Carlos Henrique Gomes Martins, Camilla Christian Gomes Moura, Ana Paula Turrioni. Antibacterial activity of Brazilian red propolis and in vitro evaluation of free radical production. Archives of oral biology. 2022 Nov; 143(?):105520. doi: 10.1016/j.archoralbio.2022.105520. [PMID: 36049430]
  • Yu-Chuen Huang, Chun-Ping Huang, Chin-Ping Lin, Kai-Chien Yang, Yu-Jie Lei, Hao-Pei Wang, Yueh-Hsiung Kuo, Yu-Jen Chen. Naturally Occurring Bicoumarin Compound Daphnoretin Inhibits Growth and Induces Megakaryocytic Differentiation in Human Chronic Myeloid Leukemia Cells. Cells. 2022 10; 11(20):. doi: 10.3390/cells11203252. [PMID: 36291120]
  • Aloke Purkait, Debasish Rana, Argha Banerjee, Dipak Kumar Hazra, Pabitra Kumar Biswas, Ramen Kumar Kole. Selection of green carrier solvent for the effective creation of bio-inspired liquid formulation and anti-fungal potency evaluation. Archives of microbiology. 2022 Oct; 204(11):669. doi: 10.1007/s00203-022-03280-3. [PMID: 36224280]
  • Simon Fabiunke, Christian Fillafer, Matthias F Schneider. Unitary Response of Solvatochromic Dye to Pulse Excitation in Lipid and Cell Membranes. Langmuir : the ACS journal of surfaces and colloids. 2022 10; 38(40):12408-12413. doi: 10.1021/acs.langmuir.2c02261. [PMID: 36154016]
  • Yibo Jin, Yongjuan Zhao, Shukang Ai, Xiujiao Chen, Xiaomin Liu, Hongying Wang, Yunqi Han, Fengwang Ma, Chao Li. Induction of polyploid Malus prunifolia and analysis of its salt tolerance. Tree physiology. 2022 10; 42(10):2100-2115. doi: 10.1093/treephys/tpac053. [PMID: 35532080]
  • A Mujib, Samar Fatima, Moien Qadir Malik. Cryo-derived plants through embryogenesis showed same levels of vinblastine and vincristine (anticancer) in Catharanthus roseus and had normal genome size. Scientific reports. 2022 10; 12(1):16635. doi: 10.1038/s41598-022-20993-z. [PMID: 36198853]
  • María Elena Hergueta-Castillo, Rosalía López-Ruiz, Antonia Garrido Frenich, Roberto Romero-González. Characterization of the composition of plant protection products in different formulation types employing suspect screening and unknown approaches. Journal of the science of food and agriculture. 2022 Oct; 102(13):5995-6004. doi: 10.1002/jsfa.11952. [PMID: 35451129]
  • Gulin Ozdamar Unal, Arif Demirdas, Mustafa Nazıroglu, Ishak Suat Ovey. Agomelatine attenuates calcium signaling and apoptosis via the inhibition of TRPV1 channel in the hippocampal neurons of rats with chronic mild stress depression model. Behavioural brain research. 2022 09; 434(?):114033. doi: 10.1016/j.bbr.2022.114033. [PMID: 35914635]
  • Reda F A Abdelhameed, Shaimaa A Fattah, Eman T Mehanna, Dina M Hal, Sarah M Mosaad, Maged S Abdel-Kader, Amany K Ibrahim, Safwat A Ahmed, Jihan M Badr, Enas E Eltamany. Zygo-Albuside A: New Saponin from Zygophyllum album L. with Significant Antioxidant, Anti-Inflammatory and Antiapoptotic Effects against Methotrexate-Induced Testicular Damage. International journal of molecular sciences. 2022 Sep; 23(18):. doi: 10.3390/ijms231810799. [PMID: 36142712]
  • Dian-Ping Yang, Ying Zhang, Pei-Min Lin, An-Qiong Mao, Qing Liu. [Analgesic effect and mechanism of electroacupuncture on SNI rats based on microglia-BDNF-neuron signal]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. 2022 Sep; 42(9):1029-36. doi: 10.13703/j.0255-2930.20210617-0004. [PMID: 36075600]
  • Yi-Ping Li, Ting-Ting Qiang, Ke-Yan Wang, Xiao-Long Wang. Shexiang Baoxin Pill Regulates Intimal Hyperplasia, Migration, and Apoptosis after Platelet-Derived Growth Factor-BB-Stimulation of Vascular Smooth Muscle Cells via miR-451. Chinese journal of integrative medicine. 2022 Sep; 28(9):785-793. doi: 10.1007/s11655-022-2891-6. [PMID: 35840853]
  • Elizabeth A Tanner, Melody A Gary, Stephan Michalik, Asheal A Davis, Brian K McFarlin. Optimized Curcumin, Pomegranate Extract, and Methylsulfonylmethane Reduce Acute, Systemic Inflammatory Response to a Half-marathon Race. Alternative therapies in health and medicine. 2022 Sep; 28(6):72-81. doi: . [PMID: 32619204]
  • Makoto Ogata, Mao Sakamoto, Noriko Yamauchi, Masato Nakazawa, Ami Koizumi, Remi Anazawa, Kenichi Kurumada, Kazuya I P J Hidari, Hiroyuki Kono. Optimization of the conditions for the immobilization of glycopolypeptides on hydrophobic silica particulates and simple purification of lectin using glycopolypeptide-immobilized particulates. Carbohydrate research. 2022 Sep; 519(?):108624. doi: 10.1016/j.carres.2022.108624. [PMID: 35749901]
  • Xin Wu, Patrick Wang, William Lewis, Yun-Bao Jiang, Philip A Gale. Measuring anion binding at biomembrane interfaces. Nature communications. 2022 08; 13(1):4623. doi: 10.1038/s41467-022-32403-z. [PMID: 35941124]
  • Monika A Roy, Charlotte K Gridley, Sida Li, Yeonhwa Park, Alicia R Timme-Laragy. Nrf2a dependent and independent effects of early life exposure to 3,3'-dichlorobiphenyl (PCB-11) in zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 2022 Aug; 249(?):106219. doi: 10.1016/j.aquatox.2022.106219. [PMID: 35700651]
  • Naifu Jin, Yueqiao Liu, Xinzi Wang, Kai Yang, Dayi Zhang, Aizhong Ding. In-vitro toxicity assessment of Eucalyptus robusta Smith extracts via whole-cell bioreporter. Ecotoxicology and environmental safety. 2022 Jul; 240(?):113704. doi: 10.1016/j.ecoenv.2022.113704. [PMID: 35653968]
  • Míria Benetati Delgado Bertéli, Cassia Renata Pinheiro, Biane Oliveira Philadelpho, Deborah Murowaniecki Otero, Camila Duarte Ferreira Ribeiro, Carolina Oliveira de Souza, Ederlan de Souza Ferreira, Suelen Pereira Ruiz, Juliana Silveira do Valle, Giani Andrea Linde, Nelson Barros Colauto. Long-term cryopreservation of Lentinus crinitus strains by wheat grain technique. Journal of microbiological methods. 2022 07; 198(?):106491. doi: 10.1016/j.mimet.2022.106491. [PMID: 35588992]
  • Diego Agustín Abelleyra Lastoria, Nicholas Raison, Abdullatif Aydin, Shamim Khan, Prokar Dasgupta, Kamran Ahmed. Comparing surgical interventions for interstitial cystitis: A systematic review. Lower urinary tract symptoms. 2022 Jul; 14(4):218-241. doi: 10.1111/luts.12441. [PMID: 35393778]
  • Rong Li, Wenqiang Zhu, Piaopiao Huang, Chen Ding, Yaxin Tang, Ping'an Lian, Xiansheng Huang. Olanzapine causes non-alcoholic fatty liver disease via inhibiting the secretion of apolipoprotein A5. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. 2022 Jun; 47(6):730-738. doi: 10.11817/j.issn.1672-7347.2022.210269. [PMID: 35837772]
  • Samilla Alves Sobral, Carolina Magri Ferraz, Rômulo Inácio Lopes Souza, Luanderson Mendes Queiroz, Natália Reinó, Otavio Luiz Fidelis Junior, Fernando Luiz Tobias, José Antônio Lima Correia, Jackson Victor Araújo, Vinicius Ribeiro Longo Vilela, Filippe Elias Freitas Soares, Fabio Ribeiro Braga. Association between Duddingtonia flagrans, dimethylsulfoxide and ivermectin for the control of Rhabditis spp. in cattle. Tropical animal health and production. 2022 Jun; 54(4):198. doi: 10.1007/s11250-022-03197-5. [PMID: 35666291]
  • Mahira Mehanović, Tamara Ćetković, Maida Hadžić, Jasmina Čakar, Sanja Ćavar Zeljković, Sanin Haverić, Anja Haverić. Genotoxic and cytotoxic assessment of two endemic Lamiaceae species from Bosnia and Herzegovina. Natural product research. 2022 Jun; 36(11):2888-2892. doi: 10.1080/14786419.2021.1925275. [PMID: 34018885]
  • M H Blank, G A Novaes, J D A Losano, S S Sant'Anna, S E M Vieira, K F Grego, R J G Pereira. Insights on sperm assays and cryopreservation in six Neotropical pit vipers. Cryobiology. 2022 06; 106(?):55-65. doi: 10.1016/j.cryobiol.2022.04.003. [PMID: 35443195]
  • X F Hong, L Li, Z X Yang, J Yan. [Paeoniflorin improves myocardial injury via inhibition of Src/VE-cadherin pathway in septic rats]. Zhonghua nei ke za zhi. 2022 Jun; 61(6):652-658. doi: 10.3760/cma.j.cn112138-20210811-00545. [PMID: 35673745]
  • Cameron V Fili, Ling Lin, Jonathan Chapman, David Hamilton, Charles R Yates. Methylsulfonylmethane and Sesame Seed Oil Improve Dyslipidemia and Modulate Polyunsaturated Fatty Acid Metabolism in Two Mouse Models of Diabetes. Journal of medicinal food. 2022 Jun; 25(6):607-617. doi: 10.1089/jmf.2021.0196. [PMID: 35708633]
  • Anaïs Biclot, Geert R B Huys, Rodrigo Bacigalupe, Kevin D'hoe, Doris Vandeputte, Gwen Falony, Raul Y Tito, Jeroen Raes. Effect of cryopreservation medium conditions on growth and isolation of gut anaerobes from human faecal samples. Microbiome. 2022 05; 10(1):80. doi: 10.1186/s40168-022-01267-2. [PMID: 35644616]
  • Min Zhao, Qiaoqiao Chang, Hua Yang, Min Wang, Yongfeng Liu, Na Lv, Qiang Lei, Hongen Wei. Epothilone D Modulates Autism-like Behaviors in the BTBR Mouse Model of Autism Spectrum Disorder. Neuroscience. 2022 05; 490(?):171-181. doi: 10.1016/j.neuroscience.2022.02.025. [PMID: 35227832]
  • Haiyang Cui, Markus Vedder, Lingling Zhang, Karl-Erich Jaeger, Ulrich Schwaneberg, Mehdi D Davari. Polar Substitutions on the Surface of a Lipase Substantially Improve Tolerance in Organic Solvents. ChemSusChem. 2022 May; 15(9):e202102551. doi: 10.1002/cssc.202102551. [PMID: 35007408]
  • Jonathan A Sreter, Thomas L Foxall, Krisztina Varga. Intracellular and Extracellular Antifreeze Protein Significantly Improves Mammalian Cell Cryopreservation. Biomolecules. 2022 05; 12(5):. doi: 10.3390/biom12050669. [PMID: 35625597]
  • Azra Bozcaarmutlu, Canan Sapmaz, Ömer Bozdoğan, Aysel Kükner, Leyla Kılınç, Salih Tunç Kaya, Oğulcan Talat Özarslan, Didem Ekşioğlu. The effect of co-administration of berberine, resveratrol, and glibenclamide on xenobiotic metabolizing enzyme activities in diabetic rat liver. Drug and chemical toxicology. 2022 May; 45(3):990-998. doi: 10.1080/01480545.2020.1802475. [PMID: 32762264]
  • C Martinaud, H H R Sugier, O Javaudin, N Burin des Roziers, S Bégué. In vitro characteristics of cryopreserved platelet concentrates reconstituted by fresh frozen or lyophilized plasma. Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine. 2022 May; 29(2):118-123. doi: 10.1016/j.tracli.2022.01.003. [PMID: 35032661]
  • Chris J Malajczuk, Sławomir S Stachura, James O Hendry, Ricardo L Mancera. Redefining the Molecular Interplay between Dimethyl Sulfoxide, Lipid Bilayers, and Dehydration. The journal of physical chemistry. B. 2022 04; 126(13):2513-2529. doi: 10.1021/acs.jpcb.2c00353. [PMID: 35344357]
  • Nicoleta-Luminita Dumitrescu, Madalina Icriverzi, Anca Bonciu, Paula Florian, Antoniu Moldovan, Anca Roseanu, Laurentiu Rusen, Valentina Dinca, Florin Grama. New Poly(N-isopropylacrylamide-butylacrylate) Copolymer Biointerfaces and Their Characteristic Influence on Cell Behavior In Vitro. International journal of molecular sciences. 2022 Apr; 23(7):. doi: 10.3390/ijms23073988. [PMID: 35409347]
  • S Hasan Radhi, S A Kamal, N Mohammed Sahi, H J Hussein. Assessment of Antibacterial Efficacy of Callistemon viminalis (Sol. ex Gaertn.) G. Don against Some Isolates Obtained from Urinary Tract Infections. Archives of Razi Institute. 2022 Apr; 77(2):891-897. doi: 10.22092/ari.2022.357125.1981. [PMID: 36284981]
  • Carly Young, Nicole Ravida, Michael Rochford, Frank Mazzotti, Michelle Curtis, Barbara Durrant. Sperm cryopreservation in the Burmese python Python bivittatus as a model for endangered snakes. Reproduction, fertility, and development. 2022 Mar; 34(5):401-409. doi: 10.1071/rd21023. [PMID: 34412771]
  • Ryota Imura, Atsuko Nakanishi Ozeki, Nanako Shida, Mika Kobayashi, Hiroyuki Ida, Youichiro Wada, Nobuyoshi Akimitsu, Yoshitaka Kumakura. Radiolabeling of PSMA-617 with 89Zr: A novel use of DMSO to improve radiochemical yield and preliminary small-animal PET results. Nuclear medicine and biology. 2022 Mar; 106-107(?):21-28. doi: 10.1016/j.nucmedbio.2021.12.003. [PMID: 34998216]
  • Richa Kaushal, Suria Jahan, Chelsea McGregor, Nicolas Pineault. Dimethyl sulfoxide-free cryopreservation solutions for hematopoietic stem cell grafts. Cytotherapy. 2022 03; 24(3):272-281. doi: 10.1016/j.jcyt.2021.09.002. [PMID: 34654640]
  • Jin Wang, Xiaodi Shi, Minghao Xiong, Wen-Song Tan, Haibo Cai. Trehalose glycopolymers for cryopreservation of tissue-engineered constructs. Cryobiology. 2022 02; 104(?):47-55. doi: 10.1016/j.cryobiol.2021.11.004. [PMID: 34800528]
  • Grzegorz Bartosz, Natalia Pieńkowska, Izabela Sadowska-Bartosz. Dosing metric in cellular experiments: The mol/cell metric has its limitations. Toxicology in vitro : an international journal published in association with BIBRA. 2022 Feb; 78(?):105272. doi: 10.1016/j.tiv.2021.105272. [PMID: 34740775]
  • Adel Saberivand, Seddigheh Pashapour, Amirhessam Eskafi Noghani, Zahra Namvar. Synergistic effect of royal jelly in combination with glycerol and dimethyl sulfoxide on cryoprotection of Romanov ram sperm. Cryobiology. 2022 02; 104(?):87-97. doi: 10.1016/j.cryobiol.2021.05.006. [PMID: 34077710]
  • Shinichiro F Ichise, Takaki Koide. Synthetic Collagen-like Polymer That Undergoes a Sol-Gel Transition Triggered by O-N Acyl Migration at Physiological pH. International journal of molecular sciences. 2022 Jan; 23(3):. doi: 10.3390/ijms23031584. [PMID: 35163505]
  • Kevin F O'Connell. Cryopreservation of C. elegans and Other Nematodes with Dimethyl Sulfoxide and Trehalose. Methods in molecular biology (Clifton, N.J.). 2022; 2468(?):43-49. doi: 10.1007/978-1-0716-2181-3_3. [PMID: 35320559]
  • Tingyao Zhao, Xinting Wang, Qian Liu, Tianshu Yang, Huiyan Qu, Hua Zhou. Ginsenoside Rd Promotes Cardiac Repair After Myocardial Infarction by Modulating Monocytes/Macrophages Subsets Conversion. Drug design, development and therapy. 2022; 16(?):2767-2782. doi: 10.2147/dddt.s377624. [PMID: 36033133]
  • Abdul S Ansari, Mubarik Hussain, Sadi Rehan Khan, Ayesha Badar, Barkha Khilwani, Nirmal Kumar Lohiya. Studies on biochemical, oxidative and genotoxicity alterations following vas blockage with reversible inhibition of sperm under guidance and reversal in rats. Indian journal of pharmacology. 2022 Jan; 54(1):33-40. doi: 10.4103/ijp.ijp_557_20. [PMID: 35343205]
  • Rimanshee Arya, Vishal Prashar, Mukesh Kumar. Evaluating Stability and Activity of SARS-CoV-2 PLpro for High-throughput Screening of Inhibitors. Molecular biotechnology. 2022 Jan; 64(1):1-8. doi: 10.1007/s12033-021-00383-y. [PMID: 34420183]
  • Yueming Guo, Pengpeng Li, Zongliang Wang, Peibiao Zhang, Xiaodong Wu. Sustained Delivery of Methylsulfonylmethane from Biodegradable Scaffolds Enhances Efficient Bone Regeneration. International journal of nanomedicine. 2022; 17(?):4829-4842. doi: 10.2147/ijn.s377036. [PMID: 36246935]
  • Aasia Kalsoom, Awais Altaf, Muhammad Ashraf, Muhammad Muddassir Ali, Saira Aftab, Huma Sattar, Muhammad Sajjad, Amjad Islam Aqib, Tahir Maqbool. In Vitro Evaluation of Cytotoxic Potential of Caladium lindenii Extracts on Human Hepatocarcinoma HepG2 and Normal HEK293T Cell Lines. BioMed research international. 2022; 2022(?):1279961. doi: 10.1155/2022/1279961. [PMID: 36193312]
  • Grace Massiah, Giuseppe De Palma, Antonio Negri, Fabio Mele, Donato Loisi, Angelo Virgilio Paradiso, Cosmo Maurizio Ressa. Cryopreservation of adipose tissue with and without cryoprotective agent addition for breast lipofilling: A cytological and histological study. Cryobiology. 2021 12; 103(?):141-146. doi: 10.1016/j.cryobiol.2021.07.016. [PMID: 34333035]
  • Da-Yeon Lee, Chan-Yang Lee, Jin-Na Shin, Jeong-Ho Oh, Soon-Mi Shim. Impact of soy lecithin, zinc oxide, and methylsulfonylmethane, as excipient ingredients, on the bioaccessibility and intestinal transport of branched-chain amino acids from animal and plant protein mixtures. Food & function. 2021 Nov; 12(22):11399-11407. doi: 10.1039/d1fo01712h. [PMID: 34673869]
  • Renata Gilfanova, Andrea Callegari, Adam Childs, Gaomai Yang, Miranda Luarca, Alan G Gutierrez, Karla I Medina, Justin Mai, Alvin Hui, Mark Kline, Xiaoxi Wei, Philip J Norris, Marcus O Muench. A bioinspired and chemically defined alternative to dimethyl sulfoxide for the cryopreservation of human hematopoietic stem cells. Bone marrow transplantation. 2021 11; 56(11):2644-2650. doi: 10.1038/s41409-021-01368-w. [PMID: 34155359]
  • Chin-Yi Cheng, Hui-Chi Huang, Shung-Te Kao, Yu-Chen Lee. Angelica sinensis extract promotes neuronal survival by enhancing p38 MAPK-mediated hippocampal neurogenesis and dendritic growth in the chronic phase of transient global cerebral ischemia in rats. Journal of ethnopharmacology. 2021 Oct; 278(?):114301. doi: 10.1016/j.jep.2021.114301. [PMID: 34090910]
  • Dorothy Priyanka Dorairaj, Ya-Fan Lin, Jebiti Haribabu, Theetharappan Murugan, Manmath Narwane, Ramasamy Karvembu, Mallanpillai Ananthakrishnan Neelakantan, Chai-Lin Kao, Chien-Chih Chiu, Sodio C N Hsu. Binding mode transformation and biological activity on the Ru(II)-DMSO complexes bearing heterocyclic pyrazolyl ligands. Journal of inorganic biochemistry. 2021 10; 223(?):111545. doi: 10.1016/j.jinorgbio.2021.111545. [PMID: 34303108]
  • C G Lucas, B K Redel, P R Chen, L D Spate, R S Prather, K D Wells. Effects of RAD51-stimulatory compound 1 (RS-1) and its vehicle, DMSO, on pig embryo culture. Reproductive toxicology (Elmsford, N.Y.). 2021 10; 105(?):44-52. doi: 10.1016/j.reprotox.2021.08.002. [PMID: 34407461]
  • Liting Ye, Ruifang Ye, Fengxian Hu, Guozhu Wang. Combination of atmospheric and room temperature plasma (ARTP) mutagenesis, genome shuffling and dimethyl sulfoxide (DMSO) feeding to improve FK506 production in Streptomyces tsukubaensis. Biotechnology letters. 2021 Sep; 43(9):1809-1820. doi: 10.1007/s10529-021-03154-6. [PMID: 34160747]
  • Juliana C Ferreira, Samar Fadl, Metehan Ilter, Hanife Pekel, Rachid Rezgui, Ozge Sensoy, Wael M Rabeh. Dimethyl sulfoxide reduces the stability but enhances catalytic activity of the main SARS-CoV-2 protease 3CLpro. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2021 08; 35(8):e21774. doi: 10.1096/fj.202100994. [PMID: 34324734]
  • Wen-Qian Zhu, Ning-Ning Cai, Yu Jiang, Rui Yang, Jian-Zhong Shi, Chun-Ling Zhu, Bo-Yang Zhang, Bo Tang, Xue-Ming Zhang. Survivable potential of germ cells after trehalose cryopreservation of bovine testicular tissues. Cryobiology. 2021 08; 101(?):105-114. doi: 10.1016/j.cryobiol.2021.05.001. [PMID: 33989617]
  • Gilles Coppieters, Koen Deventer, Peter Van Eenoo, Péter Judák. Combining direct urinary injection with automated filtration and nanoflow LC-MS for the confirmatory analysis of doping-relevant small peptide hormones. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2021 Aug; 1179(?):122842. doi: 10.1016/j.jchromb.2021.122842. [PMID: 34216910]
  • Tania García-Martínez, Teresa Mogas, Steven F Mullen, Iris Martínez-Rodero, Ramila E Gulieva, Adam Z Higgins. Effect of cryoprotectant concentration on bovine oocyte permeability and comparison of two membrane permeability modelling approaches. Scientific reports. 2021 07; 11(1):15387. doi: 10.1038/s41598-021-94884-0. [PMID: 34321576]
  • Dayamín Martínez Brito, Patrizia Leogrande, Cristiana Colamonici, Davide Curcio, Francesco Botre, Xavier de la Torre. Arimistane: Degradation product or metabolite of 7-oxo-DHEA?. Drug testing and analysis. 2021 Jul; 13(7):1430-1439. doi: 10.1002/dta.3036. [PMID: 33783974]
  • E Tuten Sevim, S Arat. Combining dimethyl sulphoxide (DMSO) with different cryoprotectants ensures better cartilage cell cryopreservation. Cryo letters. 2021 Jul; 42(4):220-226. doi: NULL. [PMID: 35363841]
  • Hilal Alkis, Elif Demir, Mehmet Resit Taysi, Suleyman Sagir, Seyithan Taysi. Effects of Nigella sativa oil and thymoquinone on radiation-induced oxidative stress in kidney tissue of rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Jul; 139(?):111540. doi: 10.1016/j.biopha.2021.111540. [PMID: 33831837]
  • I V Arutyunyan, E Yu Kananykhina, A V Elchaninov, T Kh Fatkhudinov. Influence of Sucrose on the Efficiency of Cryopreservation of Human Umbilical Cord-Derived Multipotent Stromal Cells with the Use of Various Penetrating Cryoprotectants. Bulletin of experimental biology and medicine. 2021 May; 171(1):150-155. doi: 10.1007/s10517-021-05187-3. [PMID: 34050836]
  • X Liu, S Robbins, J Eyles, T Fedorova, S Virk, L A Deveza, A J McLachlan, D J Hunter. Efficacy and safety of a supplement combination on hand pain among people with symptomatic hand osteoarthritis an internet-based, randomised clinical trial the RADIANT study. Osteoarthritis and cartilage. 2021 05; 29(5):667-677. doi: 10.1016/j.joca.2021.01.011. [PMID: 33617972]
  • Marc-Sebastian F Straka, Noha Abdullah Al-Otaibi, Philip D Whitfield, Mary K Doherty, Bruno F E Matarèse, Nigel K H Slater, Hassan Rahmoune. Disaccahrides-Based Cryo-Formulant Effect on Modulating Phospho/Mitochondrial Lipids and Biological Profiles of Human Leukaemia Cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2021 Apr; 55(2):206-221. doi: 10.33594/000000360. [PMID: 33914444]
  • Qin Tong, Weichun Wu, Jianghong Hu, Junhao Wang, Ke Li, Bin Dong, Bo Song. Dimethyl Sulfoxide-Free and Water-Soluble Fluorescent Probe for Detection of Bovine Serum Albumin Prepared by Ionic Co-assembly of Amphiphiles. Langmuir : the ACS journal of surfaces and colloids. 2021 04; 37(15):4532-4539. doi: 10.1021/acs.langmuir.1c00072. [PMID: 33823595]
  • Karine Grigoryan, Ashkhen Zatikyan, Hasmik Shilajyan. Effect of monovalent ions on the thermal stability of bovine serum albumin in dimethylsulfoxide aqueous solutions. Spectroscopic approach. Journal of biomolecular structure & dynamics. 2021 04; 39(6):2284-2288. doi: 10.1080/07391102.2020.1743759. [PMID: 32178588]
  • Vance G Nielsen. Platinoid effects on human plasmatic coagulation kinetics: a viscoelastic analysis. Journal of thrombosis and thrombolysis. 2021 Apr; 51(3):577-583. doi: 10.1007/s11239-020-02373-4. [PMID: 33389608]
  • Yuanyong Yao, Shixue Chen, Hu Li. An Improved System to Evaluate Superoxide-Scavenging Effects of Bioflavonoids. ChemistryOpen. 2021 04; 10(4):503-514. doi: 10.1002/open.202100013. [PMID: 33908702]
  • Thi Thanh Hanh Nguyen, Jong-Hyun Jung, Min-Kyu Kim, Sangyong Lim, Jae-Myoung Choi, Byoungsang Chung, Do-Won Kim, Doman Kim. The Inhibitory Effects of Plant Derivate Polyphenols on the Main Protease of SARS Coronavirus 2 and Their Structure-Activity Relationship. Molecules (Basel, Switzerland). 2021 Mar; 26(7):. doi: 10.3390/molecules26071924. [PMID: 33808054]