Isobutyramide (BioDeep_00000308481)

   

Volatile Flavor Compounds


代谢物信息卡片


Isobutyramide

化学式: C4H9NO (87.0684104)
中文名称: 异丁酰胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)C(=N)O
InChI: InChI=1S/C4H9NO/c1-3(2)4(5)6/h3H,1-2H3,(H2,5,6)

描述信息

D000970 - Antineoplastic Agents

同义名列表

2 个代谢物同义名

Isobutyramide; Isobutyramide



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Vincent Fiegel, Sebastien Harlepp, Sylvie Begin-Colin, Dominique Begin, Damien Mertz. Design of Protein-Coated Carbon Nanotubes Loaded with Hydrophobic Drugs through Sacrificial Templating of Mesoporous Silica Shells. Chemistry (Weinheim an der Bergstrasse, Germany). 2018 Mar; 24(18):4662-4670. doi: 10.1002/chem.201705845. [PMID: 29369435]
  • Damien Mertz, Jiwei Cui, Yan Yan, Glyn Devlin, Christophe Chaubaroux, Alexandre Dochter, Roxane Alles, Philippe Lavalle, Jean Claude Voegel, Anton Blencowe, Pascal Auffinger, Frank Caruso. Protein capsules assembled via isobutyramide grafts: sequential growth, biofunctionalization, and cellular uptake. ACS nano. 2012 Sep; 6(9):7584-94. doi: 10.1021/nn302024t. [PMID: 22950440]
  • Vikas Sharma, Jente Boonen, Nagendra S Chauhan, Mayank Thakur, Bart De Spiegeleer, V K Dixit. Spilanthes acmella ethanolic flower extract: LC-MS alkylamide profiling and its effects on sexual behavior in male rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2011 Oct; 18(13):1161-9. doi: 10.1016/j.phymed.2011.06.001. [PMID: 21757328]
  • Kenji Kono, Etsuo Murakami, Yuki Hiranaka, Eiji Yuba, Chie Kojima, Atsushi Harada, Kazuo Sakurai. Thermosensitive molecular assemblies from poly(amidoamine) dendron-based lipids. Angewandte Chemie (International ed. in English). 2011 Jul; 50(28):6332-6. doi: 10.1002/anie.201101007. [PMID: 21598367]
  • Alexander W Schüttelkopf, Ludovic Gros, David E Blair, Julie A Frearson, Daan M F van Aalten, Ian H Gilbert. Acetazolamide-based fungal chitinase inhibitors. Bioorganic & medicinal chemistry. 2010 Dec; 18(23):8334-40. doi: 10.1016/j.bmc.2010.09.062. [PMID: 21044846]
  • J Boonen, B Baert, C Burvenich, P Blondeel, S De Saeger, B De Spiegeleer. LC-MS profiling of N-alkylamides in Spilanthes acmella extract and the transmucosal behaviour of its main bio-active spilanthol. Journal of pharmaceutical and biomedical analysis. 2010 Nov; 53(3):243-9. doi: 10.1016/j.jpba.2010.02.010. [PMID: 20227845]
  • Kelly C Albin, Christopher T Simons. Psychophysical evaluation of a sanshool derivative (alkylamide) and the elucidation of mechanisms subserving tingle. PloS one. 2010 Mar; 5(3):e9520. doi: 10.1371/journal.pone.0009520. [PMID: 20209090]
  • Amira M K Abouelella, Yasser E Shahein, Sameh S Tawfik, Ahmed M Zahran. Phytotherapeutic effects of Echinacea purpurea in gamma-irradiated mice. Journal of veterinary science. 2007 Dec; 8(4):341-51. doi: 10.4142/jvs.2007.8.4.341. [PMID: 17993747]
  • Nadja B Cech, Maqueita S Eleazer, Lawresa T Shoffner, Mark R Crosswhite, Amanda C Davis, Ashley M Mortenson. High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts. Journal of chromatography. A. 2006 Jan; 1103(2):219-28. doi: 10.1016/j.chroma.2005.11.008. [PMID: 16298376]
  • P Morazzoni, A Cristoni, F Di Pierro, C Avanzini, D Ravarino, S Stornello, M Zucca, T Musso. In vitro and in vivo immune stimulating effects of a new standardized Echinacea angustifolia root extract (Polinacea). Fitoterapia. 2005 Jul; 76(5):401-11. doi: 10.1016/j.fitote.2005.02.001. [PMID: 15949903]
  • Christopher M Ranger, Rudolph E K Winter, George E Rottinghaus, Elaine A Backus, David W Johnson. Mass spectral characterization of fatty acid amides from alfalfa trichomes and their deterrence against the potato leafhopper. Phytochemistry. 2005 Mar; 66(5):529-41. doi: 10.1016/j.phytochem.2005.01.012. [PMID: 15721945]
  • Rong Tsao, Chris H Marvin, A Bruce Broadbent, Martina Friesen, Wayne R Allen, Brian D McGarvey. Evidence for an isobutylamide associated with host-plant resistance to western flower thrips, Frankliniella occidentalis, in chrysanthemum. Journal of chemical ecology. 2005 Jan; 31(1):103-10. doi: 10.1007/s10886-005-0977-1. [PMID: 15839483]
  • Rong Tsao, Athula B Attygalle, Frank C Schroeder, Chris H Marvin, Brian D McGarvey. Isobutylamides of unsaturated fatty acids from Chrysanthemum morifolium associated with host-plant resistance against the western flower thrips. Journal of natural products. 2003 Sep; 66(9):1229-31. doi: 10.1021/np0301745. [PMID: 14510603]
  • Marcus A McFerren, Daniel Cordova, Eloy Rodriguez, James J Rauh. In vitro neuropharmacological evaluation of piperovatine, an isobutylamide from Piper piscatorum (Piperaceae). Journal of ethnopharmacology. 2002 Dec; 83(3):201-7. doi: 10.1016/s0378-8741(02)00224-6. [PMID: 12426087]
  • Roberto Gotti, Jessica Fiori, Mohammad Hudaib, Vanni Cavrini. Separation of alkamides from Echinacea purpurea extracts by cyclodextrin-modified micellar electrokinetic chromatography. Electrophoresis. 2002 Sep; 23(17):3084-92. doi: 10.1002/1522-2683(200209)23:17<3084::aid-elps3084>3.0.co;2-0. [PMID: 12207319]
  • J Zhang, X Zhang, P Chen. Isobutyramide activates transcription of human fetal gamma- and murine embryonic epsilon(y)-globin genes. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih. 2001 Dec; 16(4):187-93. doi: NULL. [PMID: 12903753]
  • E Lukaszewicz. Effects of semen filtration and dilution rate on morphology and fertility of frozen gander spermatozoa. Theriogenology. 2001 Jun; 55(9):1819-29. doi: 10.1016/s0093-691x(01)00524-6. [PMID: 11414487]
  • C Lans, T Harper, K Georges, E Bridgewater. Medicinal and ethnoveterinary remedies of hunters in Trinidad. BMC complementary and alternative medicine. 2001; 1(?):10. doi: 10.1186/1472-6882-1-10. [PMID: 11737880]
  • M J Haas, K Pun, D Reinacher, N C Wong, A D Mooradian. Effects of ketoacidosis on rat apolipoprotein A1 gene expression: a link with acidosis but not with ketones. Journal of molecular endocrinology. 2000 Aug; 25(1):129-39. doi: 10.1677/jme.0.0250129. [PMID: 10915225]
  • M D Cappellini, G Graziadei, L Ciceri, A Comino, P Bianchi, M Pomati, G Fiorelli. Butyrate trials. Annals of the New York Academy of Sciences. 1998 Jun; 850(?):110-9. doi: 10.1111/j.1749-6632.1998.tb10468.x. [PMID: 9668533]
  • M E Gleave, N Sato, M Sadar, V Yago, N Bruchovsky, L Sullivan. Butyrate analogue, isobutyramide, inhibits tumor growth and time to androgen-independent progression in the human prostate LNCaP tumor model. Journal of cellular biochemistry. 1998 Jun; 69(3):271-81. doi: 10.1002/(sici)1097-4644(19980601)69:3<271::aid-jcb5>3.0.co;2-o. [PMID: 9581866]
  • L R Brettman, P R Chaturvedi. Pharmacokinetics and safety of single oral doses of VX-366 (isobutyramide) in healthy volunteers. Journal of clinical pharmacology. 1996 Jul; 36(7):617-22. doi: 10.1002/j.1552-4604.1996.tb04226.x. [PMID: 8844444]
  • S P Perrine, G H Dover, P Daftari, C T Walsh, Y Jin, A Mays, D V Faller. Isobutyramide, an orally bioavailable butyrate analogue, stimulates fetal globin gene expression in vitro and in vivo. British journal of haematology. 1994 Nov; 88(3):555-61. doi: 10.1111/j.1365-2141.1994.tb05073.x. [PMID: 7529533]
  • S P Perrine, N F Olivieri, D V Faller, E P Vichinsky, G J Dover, G D Ginder. Butyrate derivatives. New agents for stimulating fetal globin production in the beta-globin disorders. The American journal of pediatric hematology/oncology. 1994 Feb; 16(1):67-71. doi: NULL. [PMID: 7508690]
  • S P Perrine, D V Faller. Butyrate-induced reactivation of the fetal globin genes: a molecular treatment for the beta-hemoglobinopathies. Experientia. 1993 Feb; 49(2):133-7. doi: 10.1007/bf01989417. [PMID: 7680003]