calphostin C (BioDeep_00000305450)
代谢物信息卡片
calphostin C
化学式: C44H38O14 (790.2261448)
中文名称: 卡弗他丁C
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(CC1=C2C3=C(C(=C(C4=C3C(=C5C2=C(C(=O)C=C5OC)C(=C1OC)O)C(=CC4=O)OC)O)OC)CC(C)OC(=O)OC6=CC=C(C=C6)O)OC(=O)C7=CC=CC=C7
InChI: InChI=1S/C44H38O14/c1-20(56-43(50)22-10-8-7-9-11-22)16-25-31-32-26(17-21(2)57-44(51)58-24-14-12-23(45)13-15-24)42(55-6)40(49)34-28(47)19-30(53-4)36(38(32)34)35-29(52-3)18-27(46)33(37(31)35)39(48)41(25)54-5/h7-15,18-21,45,48-49H,16-17H2,1-6H3
数据库引用编号
6 个数据库交叉引用编号
- PubChem: 2533
- ChEMBL: CHEMBL261214
- CAS: 924657-57-8
- CAS: 121263-19-2
- PMhub: MS000087327
- PMhub: MS000072064
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Julliana F Sant'Anna, Vanessa S Baldez, Natalie A Razuck-Garrão, Thiago Lemos, Bruno L Diaz, Marcelo Einicker-Lamas. Lysophosphatidic acid (LPA) as a modulator of plasma membrane Ca2+-ATPase from basolateral membranes of kidney proximal tubules.
Journal of physiology and biochemistry.
2021 May; 77(2):321-329. doi:
10.1007/s13105-021-00800-5. [PMID: 33704695] - Andrea Gerbino, Roberta De Zio, Daniela Russo, Luigi Milella, Serena Milano, Giuseppe Procino, Michael Pusch, Maria Svelto, Monica Carmosino. Role of PKC in the Regulation of the Human Kidney Chloride Channel ClC-Ka.
Scientific reports.
2020 06; 10(1):10268. doi:
10.1038/s41598-020-67219-8. [PMID: 32581267] - Ricardo Martín, José Javier Ferrero, Andrea Collado-Alsina, Carolina Aguado, Rafael Luján, Magdalena Torres, José Sánchez-Prieto. Bidirectional modulation of glutamatergic synaptic transmission by metabotropic glutamate type 7 receptors at Schaffer collateral-CA1 hippocampal synapses.
The Journal of physiology.
2018 03; 596(5):921-940. doi:
10.1113/jp275371. [PMID: 29280494] - Lucienne S Lara, Camille R T Bourgeois, Samir S El-Dahr, Minolfa C Prieto. Bradykinin/B2 receptor activation regulates renin in M-1 cells via protein kinase C and nitric oxide.
Physiological reports.
2017 Apr; 5(7):. doi:
10.14814/phy2.13211. [PMID: 28373410] - Gerard G Robins, Geoffrey I Sandle. Liddle-Mutation of the β-Subunit, but not the γ-Subunit, Attenuates Protein Kinase C-Mediated Inhibition of Human Epithelial Sodium Channels (hENaC).
The Journal of membrane biology.
2016 06; 249(3):271-9. doi:
10.1007/s00232-015-9866-x. [PMID: 26759146] - Elizabeth Portugal Velloso, Renata Lúcia Pimentel, Janaína F Braga, Antônio Carlos Vieira Cabral, Zilma Silveira N Reis, Michael Bader, Robson Augusto S Santos, Gerd Wallukat. Identification of a Novel Agonist-Like Autoantibody in Preeclamptic Patients.
American journal of hypertension.
2016 Mar; 29(3):405-12. doi:
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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
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American journal of nephrology.
2014; 39(5):436-48. doi:
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Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.
2013 Jun; 34(3):1759-66. doi:
10.1007/s13277-013-0714-2. [PMID: 23526078] - A Radhika, P R Sudhakaran. Upregulation of macrophage-specific functions by oxidized LDL: lysosomal degradation-dependent and -independent pathways.
Molecular and cellular biochemistry.
2013 Jan; 372(1-2):181-90. doi:
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American journal of physiology. Renal physiology.
2012 Mar; 302(6):F679-87. doi:
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Developmental and comparative immunology.
2012 Jan; 36(1):216-21. doi:
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The Journal of biological chemistry.
2011 Sep; 286(37):32045-53. doi:
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British journal of pharmacology.
2011 Jun; 163(4):857-75. doi:
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The FEBS journal.
2010 May; 277(10):2318-28. doi:
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American journal of physiology. Renal physiology.
2009 Oct; 297(4):F904-15. doi:
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2009 Sep; 110(5):1422-32. doi:
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Investigative ophthalmology & visual science.
2009 Feb; 50(2):614-20. doi:
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International journal of cancer.
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Journal of cellular physiology.
2008 Jul; 216(1):221-33. doi:
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American journal of physiology. Heart and circulatory physiology.
2008 Apr; 294(4):H1933-8. doi:
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Experimental parasitology.
2007 Aug; 116(4):419-26. doi:
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Proceedings of the National Academy of Sciences of the United States of America.
2007 May; 104(18):7516-21. doi:
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2007 Feb; 192(2):389-94. doi:
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Investigative ophthalmology & visual science.
2006 Sep; 47(9):3989-4000. doi:
10.1167/iovs.06-0253. [PMID: 16936115] - Zahra Faghiri, Nicolas G Bazan. Selective relocalization and proteasomal downregulation of PKCalpha induced by platelet-activating factor in retinal pigment epithelium.
Investigative ophthalmology & visual science.
2006 Jan; 47(1):397-404. doi:
10.1167/iovs.05-0290. [PMID: 16384990] - Chiaki Tanifuji, Yusuke Suzuki, Wong Mu Geot, Satoshi Horikoshi, Takeshi Sugaya, Marta Ruiz-Ortega, Jesus Egido, Yasuhiko Tomino. Reactive oxygen species-mediated signaling pathways in angiotensin II-induced MCP-1 expression of proximal tubular cells.
Antioxidants & redox signaling.
2005 Sep; 7(9-10):1261-8. doi:
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Free radical biology & medicine.
2005 Aug; 39(4):444-52. doi:
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2005 May; 280(20):19757-67. doi:
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2005 Apr; 9(2):387-97. doi:
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Arteriosclerosis, thrombosis, and vascular biology.
2005 Feb; 25(2):341-7. doi:
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Molecular and cellular endocrinology.
2004 Sep; 224(1-2):11-20. doi:
10.1016/j.mce.2004.07.005. [PMID: 15353176] - Yih-Wen Chen, Mark L Lang, William F Wade. Protein kinase C-alpha and -delta are required for FcalphaR (CD89) trafficking to MHC class II compartments and FcalphaR-mediated antigen presentation.
Traffic (Copenhagen, Denmark).
2004 Aug; 5(8):577-94. doi:
10.1111/j.1600-0854.2004.00202.x. [PMID: 15260828] - Daniela A Eisinger, Rüdiger Schulz. Extracellular signal-regulated kinase/mitogen-activated protein kinases block internalization of delta-opioid receptors.
The Journal of pharmacology and experimental therapeutics.
2004 May; 309(2):776-85. doi:
10.1124/jpet.103.061788. [PMID: 14742744] - C L Chik, B Li, E Karpinski, A K Ho. Ceramide inhibits L-type calcium channel currents in GH3 cells.
Molecular and cellular endocrinology.
2004 Apr; 218(1-2):175-83. doi:
10.1016/j.mce.2003.10.048. [PMID: 15130522] - Shih-Horng Huang, Wung-Jing Shen, Hui-Lin Yeo, Seu-Mei Wang. Signaling pathway of magnolol-stimulated lipolysis in sterol ester-loaded 3T3-L1 preadipocyes.
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2004 Apr; 91(5):1021-9. doi:
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The Journal of biological chemistry.
2004 Feb; 279(8):7112-8. doi:
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Journal of molecular endocrinology.
2004 Feb; 32(1):87-98. doi:
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Breast cancer research and treatment.
2003 Nov; 82(2):125-41. doi:
10.1023/b:brea.0000003969.21267.81. [PMID: 14692656] - Ji-Cheon Jeong, Sung-Koo Kang, Cheol-Ho Youn, Chang-Whan Jeong, Hyung-Min Kim, Young-Choon Lee, Young-Chae Chang, Cheorl-Ho Kim. Inhibition of Drynariae Rhizoma extracts on bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts.
International immunopharmacology.
2003 Nov; 3(12):1685-97. doi:
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Regulatory peptides.
2003 Oct; 115(3):195-201. doi:
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2003 Jul; 217(3):483-9. doi:
10.1007/s00425-003-1011-x. [PMID: 14520575] - DaoHong Lin, Hyacinth Sterling, Kenneth M Lerea, Gerhard Giebisch, Wen-Hui Wang. Protein kinase C (PKC)-induced phosphorylation of ROMK1 is essential for the surface expression of ROMK1 channels.
The Journal of biological chemistry.
2002 Nov; 277(46):44278-84. doi:
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Biochemistry.
2002 Oct; 41(41):12562-7. doi:
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European journal of pharmacology.
2002 Sep; 452(1):57-66. doi:
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Experimental hematology.
2002 Sep; 30(9):990-1000. doi:
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Biochemical and biophysical research communications.
2002 Jan; 290(1):488-93. doi:
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Blood pressure.
2002; 11(6):345-51. doi:
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American journal of physiology. Renal physiology.
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2001 Dec; 276(51):47993-9. doi:
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Arteriosclerosis, thrombosis, and vascular biology.
2001 Sep; 21(9):1408-13. doi:
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International journal of cancer.
2001 Sep; 93(6):848-54. doi:
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Toxicology and applied pharmacology.
2001 Jul; 174(1):69-77. doi:
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2001 Jun; 40(22):6589-97. doi:
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American journal of physiology. Cell physiology.
2001 Apr; 280(4):C920-8. doi:
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Journal of periodontal research.
2001 Apr; 36(2):80-7. doi:
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British journal of haematology.
2001 Mar; 112(3):697-705. doi:
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Biochemistry.
2001 Feb; 40(8):2640-6. doi:
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2001 Feb; 42(2):249-57. doi:
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