ZINC100006452 (BioDeep_00000298388)
代谢物信息卡片
ZINC100006452
化学式: C26H21N3O3 (423.1583)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: O=c1c(Cc2ccc(O)cc2)nc2c(Cc3ccccc3)[nH]c(-c3ccc(O)cc3)cn1-2
InChI:
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Lei Wang, Ziyan Liu, Sivasai Balivada, Tej Shrestha, Stefan Bossmann, Marla Pyle, Loretta Pappan, Jishu Shi, Deryl Troyer. Interleukin-1β and transforming growth factor-β cooperate to induce neurosphere formation and increase tumorigenicity of adherent LN-229 glioma cells.
Stem cell research & therapy.
2012 Feb; 3(1):5. doi:
10.1186/scrt96. [PMID: 22330721] - Takamitsu Kurusu, Daisuke Nishikawa, Yukari Yamazaki, Mariko Gotoh, Masataka Nakano, Haruyasu Hamada, Takuya Yamanaka, Kazuko Iida, Yuko Nakagawa, Hikaru Saji, Kazuo Shinozaki, Hidetoshi Iida, Kazuyuki Kuchitsu. Plasma membrane protein OsMCA1 is involved in regulation of hypo-osmotic shock-induced Ca2+ influx and modulates generation of reactive oxygen species in cultured rice cells.
BMC plant biology.
2012 Jan; 12(?):11. doi:
10.1186/1471-2229-12-11. [PMID: 22264357] - Meritxell Canals, Danny J Scholten, Sabrina de Munnik, Mitchell K L Han, Martine J Smit, Rob Leurs. Ubiquitination of CXCR7 controls receptor trafficking.
PloS one.
2012; 7(3):e34192. doi:
10.1371/journal.pone.0034192. [PMID: 22457824] - Yongqiang Zhang, Sabina Muend, Rajini Rao. Dysregulation of ion homeostasis by antifungal agents.
Frontiers in microbiology.
2012; 3(?):133. doi:
10.3389/fmicb.2012.00133. [PMID: 22493595] - Hai-Yin Li, Xue-Ming Zheng, Mei-Xia Che, Hong-Yu Hu. A redox-sensitive luciferase assay for determining the localization and topology of endoplasmic reticulum proteins.
PloS one.
2012; 7(4):e35628. doi:
10.1371/journal.pone.0035628. [PMID: 22530060] - Venkateswara R Chintapalli, Selim Terhzaz, Jing Wang, Mohammed Al Bratty, David G Watson, Pawel Herzyk, Shireen A Davies, Julian A T Dow. Functional correlates of positional and gender-specific renal asymmetry in Drosophila.
PloS one.
2012; 7(4):e32577. doi:
10.1371/journal.pone.0032577. [PMID: 22496733] - Shawn E Lupold, Tamara Johnson, Wasim H Chowdhury, Ronald Rodriguez. A real time Metridia luciferase based non-invasive reporter assay of mammalian cell viability and cytotoxicity via the β-actin promoter and enhancer.
PloS one.
2012; 7(5):e36535. doi:
10.1371/journal.pone.0036535. [PMID: 22590558] - Adnan Zubair, Peter D Burbelo, Ludovic G Vincent, Michael J Iadarola, Paul D Smith, Nicole Y Morgan. Microfluidic LIPS for serum antibody detection: demonstration of a rapid test for HSV-2 infection.
Biomedical microdevices.
2011 Dec; 13(6):1053-62. doi:
10.1007/s10544-011-9575-x. [PMID: 21826483] - Ulrike Binder, Mojca Bencina, Andrea Eigentler, Vera Meyer, Florentine Marx. The Aspergillus giganteus antifungal protein AFPNN5353 activates the cell wall integrity pathway and perturbs calcium homeostasis.
BMC microbiology.
2011 Sep; 11(?):209. doi:
10.1186/1471-2180-11-209. [PMID: 21943024] - Martin Schäfer, Christine Fischer, Stefan Meldau, Eileen Seebald, Ralf Oelmüller, Ian T Baldwin. Lipase activity in insect oral secretions mediates defense responses in Arabidopsis.
Plant physiology.
2011 Jul; 156(3):1520-34. doi:
10.1104/pp.111.173567. [PMID: 21546453] - Carlotta Giorgi, Anna Romagnoli, Chiara Agnoletto, Leda Bergamelli, Giovanni Sorrentino, Marisa Brini, Tullio Pozzan, Jacopo Meldolesi, Paolo Pinton, Rosario Rizzuto. Translocation of signalling proteins to the plasma membrane revealed by a new bioluminescent procedure.
BMC cell biology.
2011 Jun; 12(?):27. doi:
10.1186/1471-2121-12-27. [PMID: 21658234] - Andrew W Browne, Jennifer L Leddon, Mark A Currier, Jon P Williams, Jason S Frischer, Margaret H Collins, Chong H Ahn, Timothy P Cripe. Cancer screening by systemic administration of a gene delivery vector encoding tumor-selective secretable biomarker expression.
PloS one.
2011 May; 6(5):e19530. doi:
10.1371/journal.pone.0019530. [PMID: 21589655] - Laura Mezzanotte, Ivo Que, Eric Kaijzel, Bruce Branchini, Aldo Roda, Clemens Löwik. Sensitive dual color in vivo bioluminescence imaging using a new red codon optimized firefly luciferase and a green click beetle luciferase.
PloS one.
2011 Apr; 6(4):e19277. doi:
10.1371/journal.pone.0019277. [PMID: 21544210] - Donatella Pietrella, Letizia Angiolella, Elisabetta Vavala, Anna Rachini, Francesca Mondello, Rino Ragno, Francesco Bistoni, Anna Vecchiarelli. Beneficial effect of Mentha suaveolens essential oil in the treatment of vaginal candidiasis assessed by real-time monitoring of infection.
BMC complementary and alternative medicine.
2011 Feb; 11(?):18. doi:
10.1186/1472-6882-11-18. [PMID: 21356078] - Tien-Hung Lan, Sudhakiranmayi Kuravi, Nevin A Lambert. Internalization dissociates β2-adrenergic receptors.
PloS one.
2011 Feb; 6(2):e17361. doi:
10.1371/journal.pone.0017361. [PMID: 21364942] - Jian-Feng Li, Jenifer Bush, Yan Xiong, Lei Li, Matthew McCormack. Large-scale protein-protein interaction analysis in Arabidopsis mesophyll protoplasts by split firefly luciferase complementation.
PloS one.
2011; 6(11):e27364. doi:
10.1371/journal.pone.0027364. [PMID: 22096563] - Peter D Burbelo, Kathryn H Ching, Frank Esper, Michael J Iadarola, Eric Delwart, W Ian Lipkin, Amit Kapoor. Serological studies confirm the novel astrovirus HMOAstV-C as a highly prevalent human infectious agent.
PloS one.
2011; 6(8):e22576. doi:
10.1371/journal.pone.0022576. [PMID: 21829634] - Mario Bortolozzi, Marisa Brini, Nick Parkinson, Giulia Crispino, Pietro Scimemi, Romolo Daniele De Siati, Francesca Di Leva, Andrew Parker, Saida Ortolano, Edoardo Arslan, Steve D Brown, Ernesto Carafoli, Fabio Mammano. The novel PMCA2 pump mutation Tommy impairs cytosolic calcium clearance in hair cells and links to deafness in mice.
The Journal of biological chemistry.
2010 Nov; 285(48):37693-703. doi:
10.1074/jbc.m110.170092. [PMID: 20826782] - Peter D Burbelo, Nitin Seam, Sandra Groot, Kathryn H Ching, Brian L Han, G Umberto Meduri, Michael J Iadarola, Anthony F Suffredini. Rapid induction of autoantibodies during ARDS and septic shock.
Journal of translational medicine.
2010 Oct; 8(?):97. doi:
10.1186/1479-5876-8-97. [PMID: 20946647] - Takashi Kadono, Daniel Tran, Rafik Errakhi, Takuya Hiramatsu, Patrice Meimoun, Joël Briand, Mari Iwaya-Inoue, Tomonori Kawano, François Bouteau. Increased anion channel activity is an unavoidable event in ozone-induced programmed cell death.
PloS one.
2010 Oct; 5(10):e13373. doi:
10.1371/journal.pone.0013373. [PMID: 20967217] - Kiwamu Tanaka, Sarah J Swanson, Simon Gilroy, Gary Stacey. Extracellular nucleotides elicit cytosolic free calcium oscillations in Arabidopsis.
Plant physiology.
2010 Oct; 154(2):705-19. doi:
10.1104/pp.110.162503. [PMID: 20671112] - Maha M Hammad, Denis J Dupré. Chaperones contribute to G protein coupled receptor oligomerization, but do not participate in assembly of the G protein with the receptor signaling complex.
Journal of molecular signaling.
2010 Sep; 5(?):16. doi:
10.1186/1750-2187-5-16. [PMID: 20868491] - Frank Boellmann, Russell S Thomas. The identification of protein kinase C iota as a regulator of the Mammalian heat shock response using functional genomic screens.
PloS one.
2010 Jul; 5(7):e11850. doi:
10.1371/journal.pone.0011850. [PMID: 20686607] - Euiheon Chung, Hiroshi Yamashita, Patrick Au, Bakhos A Tannous, Dai Fukumura, Rakesh K Jain. Secreted Gaussia luciferase as a biomarker for monitoring tumor progression and treatment response of systemic metastases.
PloS one.
2009 Dec; 4(12):e8316. doi:
10.1371/journal.pone.0008316. [PMID: 20016816] - Roberto Moscatiello, Sara Alberghini, Andrea Squartini, Paola Mariani, Lorella Navazio. Evidence for calcium-mediated perception of plant symbiotic signals in aequorin-expressing Mesorhizobium loti.
BMC microbiology.
2009 Sep; 9(?):206. doi:
10.1186/1471-2180-9-206. [PMID: 19775463] - Kathryn Luker, Mudit Gupta, Gary Luker. Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7.
BioTechniques.
2009 Jul; 47(1):625-32. doi:
10.2144/000113126. [PMID: 19594447] - Jian-Feng Li, Eunsook Park, Albrecht G von Arnim, Andreas Nebenführ. The FAST technique: a simplified Agrobacterium-based transformation method for transient gene expression analysis in seedlings of Arabidopsis and other plant species.
Plant methods.
2009 May; 5(?):6. doi:
10.1186/1746-4811-5-6. [PMID: 19457242] - Tomoko Kagenishi, Ken Yokawa, Masaki Kuse, Minoru Isobe, François Bouteau, Tomonori Kawano. Prevention of copper-induced calcium influx and cell death by prion-derived peptide in suspension-cultured tobacco cells.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2009 May; 64(5-6):411-7. doi:
10.1515/znc-2009-5-619. [PMID: 19678548] - Alexander Pazur, Valentina Rassadina. Transient effect of weak electromagnetic fields on calcium ion concentration in Arabidopsis thaliana.
BMC plant biology.
2009 Apr; 9(?):47. doi:
10.1186/1471-2229-9-47. [PMID: 19405943] - Livia Saleh, Christoph Plieth. Fingerprinting antioxidative activities in plants.
Plant methods.
2009 Jan; 5(?):2. doi:
10.1186/1746-4811-5-2. [PMID: 19171044] - Sarah L Spiden, Mario Bortolozzi, Francesca Di Leva, Martin Hrabé de Angelis, Helmut Fuchs, Dmitry Lim, Saida Ortolano, Neil J Ingham, Marisa Brini, Ernesto Carafoli, Fabio Mammano, Karen P Steel. The novel mouse mutation Oblivion inactivates the PMCA2 pump and causes progressive hearing loss.
PLoS genetics.
2008 Oct; 4(10):e1000238. doi:
10.1371/journal.pgen.1000238. [PMID: 18974863] - Jongchan Woo, Albrecht G von Arnim. Mutational optimization of the coelenterazine-dependent luciferase from Renilla.
Plant methods.
2008 Sep; 4(?):23. doi:
10.1186/1746-4811-4-23. [PMID: 18826616] - Ning Shao, Ralph Bock. A codon-optimized luciferase from Gaussia princeps facilitates the in vivo monitoring of gene expression in the model alga Chlamydomonas reinhardtii.
Current genetics.
2008 Jun; 53(6):381-8. doi:
10.1007/s00294-008-0189-7. [PMID: 18408930] - Suresh Gopalan, Frederick M Ausubel. A metasystem of framework model organisms to study emergence of new host-microbe adaptations.
PloS one.
2008; 3(12):e3891. doi:
10.1371/journal.pone.0003891. [PMID: 19066631] - Noriko Yokoyama, Dezhong Yin, Craig C Malbon. Abundance, complexation, and trafficking of Wnt/beta-catenin signaling elements in response to Wnt3a.
Journal of molecular signaling.
2007 Oct; 2(?):11. doi:
10.1186/1750-2187-2-11. [PMID: 17961224] - Jutta Walstab, Sandra Combrink, Michael Brüss, Manfred Göthert, Beate Niesler, Heinz Bönisch. Aequorin luminescence-based assay for 5-hydroxytryptamine (serotonin) type 3 receptor characterization.
Analytical biochemistry.
2007 Sep; 368(2):185-92. doi:
10.1016/j.ab.2007.06.007. [PMID: 17617370] - Qin Huang, Victor Acha, Raylon Yow, Erik Schneider, Dhiraj K Sardar, Peter J Hornsby. Bioluminescence measurements in mice using a skin window.
Journal of biomedical optics.
2007 Sep; 12(5):054012. doi:
10.1117/1.2795567. [PMID: 17994900] - Christian E Badr, Jeffrey W Hewett, Xandra O Breakefield, Bakhos A Tannous. A highly sensitive assay for monitoring the secretory pathway and ER stress.
PloS one.
2007 Jun; 2(6):e571. doi:
10.1371/journal.pone.0000571. [PMID: 17593970] - Camilla Luccardini, Aleksey Yakovlev, Stéphane Gaillard, Marcel van 't Hoff, Alicia Piera Alberola, Jean-Maurice Mallet, Wolfgang J Parak, Anne Feltz, Martin Oheim. Getting across the plasma membrane and beyond: intracellular uses of colloidal semiconductor nanocrystals.
Journal of biomedicine & biotechnology.
2007; 2007(7):68963. doi:
10.1155/2007/68963. [PMID: 18273411] - Maya Otto-Duessel, Vazgen Khankaldyyan, Ignacio Gonzalez-Gomez, Michael C Jensen, Walter E Laug, Michael Rosol. In vivo testing of Renilla luciferase substrate analogs in an orthotopic murine model of human glioblastoma.
Molecular imaging.
2006 Apr; 5(2):57-64. doi:
NULL. [PMID: 16954019] - M L N Dubuisson, J-F Rees, J Marchand-Brynaert. Coelenterazine (marine bioluminescent substrate): a source of inspiration for the discovery of novel antioxidants.
Drug development and industrial pharmacy.
2005 Oct; 31(9):827-49. doi:
10.1080/03639040500271803. [PMID: 16305995] - Markus Fuhrmann, Amparo Hausherr, Lars Ferbitz, Thomas Schödl, Markus Heitzer, Peter Hegemann. Monitoring dynamic expression of nuclear genes in Chlamydomonas reinhardtii by using a synthetic luciferase reporter gene.
Plant molecular biology.
2004 Aug; 55(6):869-81. doi:
10.1007/s11103-004-2150-6. [PMID: 15604722] - S Bhaumik, X Z Lewis, S S Gambhir. Optical imaging of Renilla luciferase, synthetic Renilla luciferase, and firefly luciferase reporter gene expression in living mice.
Journal of biomedical optics.
2004 May; 9(3):578-86. doi:
10.1117/1.1647546. [PMID: 15189096] - Bertrand de Wergifosse, Marlène Dubuisson, Jacqueline Marchand-Brynaert, André Trouet, Jean-François Rees. Coelenterazine: a two-stage antioxidant in lipid micelles.
Free radical biology & medicine.
2004 Feb; 36(3):278-87. doi:
10.1016/j.freeradbiomed.2003.11.008. [PMID: 15036347] - Peter J K Knight, Thomas A Grigliatti. Chimeric G proteins extend the range of insect cell-based functional assays for human G protein-coupled receptors.
Journal of receptor and signal transduction research.
2004; 24(4):241-56. doi:
10.1081/rrs-200035217. [PMID: 15648445] - Hui Zhao, Timothy C Doyle, Ronald J Wong, Yuan Cao, David K Stevenson, David Piwnica-Worms, Christopher H Contag. Characterization of coelenterazine analogs for measurements of Renilla luciferase activity in live cells and living animals.
Molecular imaging.
2004 Jan; 3(1):43-54. doi:
10.1162/15353500200403181. [PMID: 15142411] - Asami Kaihara, Yasutoshi Kawai, Moritoshi Sato, Takeaki Ozawa, Yoshio Umezawa. Locating a protein-protein interaction in living cells via split Renilla luciferase complementation.
Analytical chemistry.
2003 Aug; 75(16):4176-81. doi:
10.1021/ac0300800. [PMID: 14632132] - T Issad, N Boute, S Boubekeur, D Lacasa, K Pernet. Looking for an insulin pill? Use the BRET methodology!.
Diabetes & metabolism.
2003 Apr; 29(2 Pt 1):111-7. doi:
10.1016/s1262-3636(07)70016-2. [PMID: 12746630] - Wei-Gen Li, Lynn L Stoll, James B Rice, Shao-Ping Xu, Francis J Miller, Papri Chatterjee, Ling Hu, Larry W Oberley, Arthur A Spector, Neal L Weintraub. Activation of NAD(P)H oxidase by lipid hydroperoxides: mechanism of oxidant-mediated smooth muscle cytotoxicity.
Free radical biology & medicine.
2003 Apr; 34(7):937-46. doi:
10.1016/s0891-5849(03)00032-7. [PMID: 12654483] - Axelle Arrault, Marlène Dubuisson, Sonia Gharbi, Cécile Marchand, Tony Verbeuren, Alain Rupin, Alex Cordi, Eliete Bouskela, Jean-François Rees, Jacqueline Marchand-Brynaert. Protective effect of imidazolopyrazinone antioxidants on ischemia/reperfusion injury.
Bioorganic & medicinal chemistry letters.
2003 Feb; 13(4):653-6. doi:
10.1016/s0960-894x(02)01049-1. [PMID: 12639551] - Maggi Burton, Catherine De Tollenaere, Jean-François Cavalier, Cécile Marchand, Frédérique Dussart, Jacqueline Marchand-Brynaert, Jean-François Rees. Synthesis, structure-activity relationship and in vitro evaluation of coelenterazine and coelenteramine derivatives as inhibitors of lipid peroxidation.
Free radical research.
2003 Feb; 37(2):145-58. doi:
10.1080/1071576021000036443. [PMID: 12653203] - Bernadette J Janssens, Jacqueline Marchand-Brynaert, Jean-François Rees. Protection of peroxide-treated fish erythrocytes by coelenterazine and coelenteramine.
Free radical research.
2002 Sep; 36(9):967-74. doi:
10.1080/107157621000006608. [PMID: 12448822] - Marc R Knight. Signal transduction leading to low-temperature tolerance in Arabidopsis thaliana.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
2002 Jul; 357(1423):871-5. doi:
10.1098/rstb.2002.1096. [PMID: 12171650] - Christoph Plieth, Anthony J Trewavas. Reorientation of seedlings in the earth's gravitational field induces cytosolic calcium transients.
Plant physiology.
2002 Jun; 129(2):786-96. doi:
10.1104/pp.011007. [PMID: 12068119] - T Furuichi, I C Mori, K Takahashi, S Muto. Sugar-induced increase in cytosolic Ca(2+) in Arabidopsis thaliana whole plants.
Plant & cell physiology.
2001 Oct; 42(10):1149-55. doi:
10.1093/pcp/pce150. [PMID: 11673631] - M L Dubuisson, B De Wergifosse, P Kremers, J Marchand-Brynaert, A Trouet, J F Rees. Protection against nitrofurantoin-induced oxidative stress by coelenterazine analogues and their oxidation products in rat hepatocytes.
Free radical research.
2001 Mar; 34(3):285-96. doi:
10.1080/10715760100300251. [PMID: 11264902]
