Jacaranone (BioDeep_00000293139)
代谢物信息卡片
化学式: C9H10O4 (182.0579)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC(=O)CC1(O)C=CC(=O)C=C1
InChI:
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- V V Pereira, L P Duarte, R R Silva, J A Takahashi. New jacaranone glucoside from Jacaranda oxyphylla leaves.
Natural product research.
2016 Nov; 30(21):2421-8. doi:
10.1080/14786419.2016.1195378
. [PMID: 27295283] - Xiang-Xi Yi, Yong Chen, Wen-Pei Xie, Ming-Ben Xu, Yin-Ning Chen, Cheng-Hai Gao, Ri-Ming Huang. Four new Jacaranone analogs from the fruits of a Beibu Gulf mangrove Avicennia marina.
Marine drugs.
2014 Apr; 12(5):2515-25. doi:
10.3390/md12052515
. [PMID: 24796307] - Thiago R Morais, Paulete Romoff, Oriana A Fávero, Juliana Q Reimão, Walkyria C Lourenço, André G Tempone, Angelica D Hristov, Silvia M Di Santi, João Henrique G Lago, Patricia Sartorelli, Marcelo J P Ferreira. Anti-malarial, anti-trypanosomal, and anti-leishmanial activities of jacaranone isolated from Pentacalia desiderabilis (Vell.) Cuatrec. (Asteraceae).
Parasitology research.
2012 Jan; 110(1):95-101. doi:
10.1007/s00436-011-2454-9
. [PMID: 21614544] - Mariana H Massaoka, Alisson L Matsuo, Carlos R Figueiredo, Camyla F Farias, Natália Girola, Denise C Arruda, Jorge A B Scutti, Paulete Romoff, Oriana A Favero, Marcelo J P Ferreira, João H G Lago, Luiz R Travassos. Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo.
PloS one.
2012; 7(6):e38698. doi:
10.1371/journal.pone.0038698
. [PMID: 22701695] - Jorge Lozada-Lechuga, María Luisa Villarreal, Marc-André Fliniaux, Lamine Bensaddek, Fraçois Mesnard, María del Carmen Gutiérrez, Alexandre Toshirrico Cardoso-Taketa. Isolation of jacaranone, a sedative constituent extracted from the flowers of the Mexican tree Ternstroemia pringlei.
Journal of ethnopharmacology.
2010 Feb; 127(2):551-4. doi:
10.1016/j.jep.2009.11.020
. [PMID: 19951739] - Kirsten A Leiss, Young H Choi, Ibrahim B Abdel-Farid, Robert Verpoorte, Peter G L Klinkhamer. NMR metabolomics of thrips (Frankliniella occidentalis) resistance in Senecio hybrids.
Journal of chemical ecology.
2009 Feb; 35(2):219-29. doi:
10.1007/s10886-008-9586-0
. [PMID: 19169751] - Xiao-Yan Tian, Ying-Hong Wang, Qing-Yun Yang, Shi-Shan Yu, Wei-Shuo Fang. Jacaranone analogs from Senecio scandens.
Journal of Asian natural products research.
2009; 11(1):63-8. doi:
10.1080/10286020802413239
. [PMID: 19177240] - Monica Rosa Loizzo, Rosa Tundis, Giancarlo Antonio Statti, Francesco Menichini. Jacaranone: a cytotoxic constituent from Senecio ambiguus subsp. ambiguus (biv.) DC. against renal adenocarcinoma ACHN and prostate carcinoma LNCaP cells.
Archives of pharmacal research.
2007 Jun; 30(6):701-7. doi:
10.1007/bf02977631
. [PMID: 17679547] - Xiao-Yan Tian, Ying-Hong Wang, Qing-Yun Yang, Xin Liu, Wei-Shuo Fang, Shi-Shan Yu. Jacaranone glycosides from Senecio scandens.
Journal of Asian natural products research.
2006 Jan; 8(1-2):125-32. doi:
10.1080/10286020500530912
. [PMID: 16753793] - M R Loizzo, R Tundis, G A Statti, F Menichini, P J Houghton. In-vitro antiproliferative effects on human tumour cell lines of extracts and jacaranone from Senecio leucanthemifolius Poiret.
The Journal of pharmacy and pharmacology.
2005 Jul; 57(7):897-901. doi:
10.1211/0022357056398
. [PMID: 15969950] - Hanhong Xu, Nanjing Zhang, John E Casida. Insecticides in Chinese medicinal plants: survey leading to jacaranone, a neurotoxicant and glutathione-reactive quinol.
Journal of agricultural and food chemistry.
2003 Apr; 51(9):2544-7. doi:
10.1021/jf021164x
. [PMID: 12696934] - P Torres, C Grande, J Anaya, M Grande. Secondary metabolites from Senecio minutus and Senecio boissieri: a new jacaranone derivative.
Fitoterapia.
2000 Feb; 71(1):91-3. doi:
10.1016/s0367-326x(99)00119-7
. [PMID: 11449483] - J M Pezzuto, C T Che, D D McPherson, J P Zhu, G Topcu, C A Erdelmeier, G A Cordell. DNA as an affinity probe useful in the detection and isolation of biologically active natural products.
Journal of natural products.
1991 Nov; 54(6):1522-30. doi:
10.1021/np50078a006
. [PMID: 1812211] - G T Tan, J M Pezzuto, A D Kinghorn, S H Hughes. Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.
Journal of natural products.
1991 Jan; 54(1):143-54. doi:
10.1021/np50073a012
. [PMID: 1710653]